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2篇 您的检索式:作者名="A.Maidment"
    题名 作者 年代 出处 被引量
1数字乳腺X线摄影和中心组合断层投照对乳腺密度百分比的估算显示文摘目的评价临床数字乳腺X线摄影与中心组合数字乳腺断层(DBT)投照成像估算乳腺密度百分比(PD)读片者间和同一读片者内的一致性。材料与方法本研究经学术委员会通过并符合健康医疗保险要求,所有病人均签署知情同意书。对39例女性(31~80岁.平均年龄51岁)的匿名数字乳腺x线摄影和中心DBT投照行乳腺PD估算。P.R.Bakic A.K.Carton D.Kontos C.Zhang A.B.Troxel A.Maidment 秦乃姗 2009国际医学放射学杂志2009,32,5:9
2Quantitative and structural analysis of isotopically labelled natural crosslinks in type I skin collagen using LC-HRMS and SANS显示文摘Collagen structure in biological tissues imparts its intrinsic physical properties by the formation of several covalent crosslinks.For the first time,two major crosslinks in the skin dihydroxylysinonorleucine(HLNL)and histidinohydroxymerodesmosine(HHMD),were isotopically labelled and then analysed by liquid-chromatography high-resolution accurate-mass mass spectrometry(LC-HRMS)and small-angle neutron scattering(SANS).The isotopic labelling followed by LC-HRMS confirmed the presence of one imino group in both HLNL and HHMD,making them more susceptible to degrade at low pH.The structural changes in collagen due to extreme changes in the pH and chrome tanning were highlighted by the SANS contrast variation between isotopic labelled and unlabelled crosslinks.This provided a better understanding of the interaction of natural crosslinks with the chromium sulphate in collagen suggesting that the development of a benign crosslinking method can help retain the intrinsic physical properties of the leather.This analytical method can also be applied to study artificial crosslinking in other collagenous tissues for biomedical applications.Yi Zhang Rafea Naffa Christopher J.Garvey Catherine A.Maidment Sujay Prabakar 2019Journal of Leather Science and Engineering2019,1,1:0
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