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| 1 | Determinants of Blood and Body Fluid Exposure in a Large Teaching Hospital: Hazards of the In- termittent Intravenous Procedure 显示文摘 | Yassi A McGill M | 1991 | Am J Infect Control1991，19，3： | 1 |
| 2 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 3 | Efficacy and cost effectiveness of a needleless intravenous access system 显示文摘 | Yassi A Mcgill M Khokhar J | 1995 | AJIC1995，23，2： | 1 |
| 4 | Work-relatedness of low back pain in nursing personnel:a systematic review显示文摘 | Yassi A Lockhart K | 2013 | International Journal of Occupational and Environmental Health2013，19，3： | 1 |
| 5 | Determinants of Blood and Body Fluid Exposure ina Large Teaching Hospital : Hazards of the Intermittent IntravenousProcedure显示文摘 | Yassi A McGill M | 1991 | Am J Infect Control1991，19，3： | 1 |
| 6 | Evaluation of a violence risk assessment system (the Alert System) for reducing violence in an acute hospital: a before and after study显示文摘 | Kling R N Yassi A Smailes E | 2011 | Int J Nurs Stud2011，48，53： | 1 |
| 7 | Developing Ecosystem Health Indicators in Centro Habana: a Community-based Approach 显示文摘 | Spiegel JM Bonet M Yassi A | 2001 | Ecosystem Health2001，7，1： | 1 |
| 8 | The Epidemiology of Back Injuries in Nurses at a Large Canadian Tertiary Care Hos- pital: Implications for Prevention显示文摘 | Yassi A Khokhar J Tate R | 1995 | Occup Med1995，45，4： | 1 |
| 9 | Allergic eye reaction to pho- tocopier chemicals 显示文摘 | Yassi A Warrington R J | 1988 | Journal of Occupational and Environmental Medicine1988，30，5： | 1 |
| 10 | Allergic eye reaction tophotocopier chemicals显示文摘 | Yassi A Warrington RJ | 1988 | J Occup Med1988，30，5： | 1 |
| 11 | Determants of tuberculin reactivity among health care workers:interpretation of positivity following BCG vaccination 显示文摘 | Mchay A kraut A Murdzak C Yassi A | 1999 | Can J Infect Dies1999，10，： | 1 |
| 12 | Applying an ecosystem approach to the determinants of health in centro habana显示文摘 | Yassi A Mas P Bonet M | 1999 | Ecosystem Health1999，5，： | 1 |
| 13 | Work- related museuloskeletal disorders 显示文摘 | Yassi A | 2000 | Curr Opin Rheumatol2000，12，4： | 1 |
| 14 | The epidemiology of back injuries in nurses at a large Canadian tertiary care hospital:Implications for prevention显示文摘 | Yassi A Khokhar J Tare R | 1995 | Occup Med(lond)1995，45，4： | 1 |
| 15 | Developing Ecosystem Health Indicators in Centro Habana:A Co mmunity-based Approach显示文摘 | Spiegel J M Bonet M Yassi A | 2001 | Ecosystem Health2001，7，1： | 1 |
| 16 | Stakeholder, Evidence - based approach 显示文摘 | A Yassi D Moore J Mark Fitz Gerald Research Gaps IN Protecting Healthcare Workers From SARS and Other respiratory Pathogens= An interdisciplinary multi - | 2005 | JOEM2005，47，1： | 1 |
| 17 | Modelling gastrointestinal bioelectric activity 显示文摘 | Pullan A Cheng L Yassi R | 2004 | Prog Biophys Mol Bio2004，85，23： | 1 |
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