|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Early palliative care for patients with metastatic non-small-cell lung cancer显示文摘Comments This landmark article demonstrates that integration of early palliative care with standard oncologic practice shortly after diagnosis may improve quality of life,mood,and overall survival for adults with advanced non-small-cell lung cancer(NSCLC).If validated,these findings could support a paradigm shift in the care of adults with metastatic NSCLC and possibly patients with other tumor types characterized by short survival and high symptom burden. | Temel JS Greer JA Muzikansky A Gallagher ER Admane S Jackson VA Dahlin CM Blinderman CD Jacobsen J Pirl WF Billings JA Lynch TJ | 2010 | 中国肺癌杂志2010，13，9： | 165 |
| 2 | 成人、儿童及孕妇特发性血小板减少性紫癜诊治指南显示文摘特发性血小板减少性紫癜(ITP)是一种自体免疫性疾病,以持续性血小板减少为特征(血小板<150×109/L).其发病机理是自身抗体与血小板抗原结合导致它们在未成熟时即被网状内皮系统,特别是在脾脏中被破坏引起血小板减少. | Provan D Newland A Norfolk D Bolton-Maggs P Lilleyman J Greer I May A Murphy M Ouwehand W Watson S 李振宇 徐开林 | 2004 | 国外医学(输血及血液学分册)2004，27，4： | 25 |
| 3 | Clinical outcomes of isolated renal failure compared to other forms of organ failure in patients with severe acute pancreatitis显示文摘AIM To assess differences in clinical outcomes of isolated renal failure(RF) compared to other forms of organ failure(OF) in patients with severe acute pancreatitis(SAP).METHODS Using a prospectively maintained database of patients with acute pancreatitis admitted to a tertiary medical center between 2003 and 2016, those with evidence of persistent OF were classified to renal, respiratory, cardiovascular, or multi-organ(2 or more organs). Data regarding demographics, comorbidities, etiology of acute pancreatitis, and clinical outcomes were prospectively recorded. Differences in clinical outcomes after development of isolated RF in comparison to other forms of OF were determined using independent t and Mann-Whitney U tests for continues variables, and χ~2 test for discrete variables.RESULTS Among 500 patients with acute pancreatitis, 111 patients developed persistent OF: mean age was 54 years, and 75(67.6%) were male. Forty-three patients had isolated OF: 17(15.3%) renal, 25(21.6%) respiratory, and 1(0.9%) patient with cardiovascular failure. No differences in demographics, etiology of acute pancreatitis, systemic inflammatory response syndrome scores, or development of pancreatic necrosis were seen between patients with isolated RF vs isolated respiratory failure. Patients with isolated RF were less likely to require nutritional support(76.5% vs 96%, P = 0.001), ICU admission(58.8% vs 100%, P = 0.001), and had shorter mean ICU stay(2.4 d vs 15.7 d, P < 0.001), compared to isolated respiratory failure. None of the patients with isolated RF or isolated respiratory failure died.CONCLUSION Among patients with SAP per the Revised Atlanta Classification, approximately 15% develop isolated RF. This subgroup seems to have a less protracted clinical course compared to other forms of OF. Isolated RF might be weighed less than isolated respiratory failure in risk predictive modeling of acute pancreatitis. | Amir Gougol Mohannad Dugum Anwar Dudekula Phil Greer Adam Slivka David C Whitcomb Dhiraj Yadav Georgios I Papachristou | 2017 | World Journal of Gastroenterology2017，23，29： | 20 |
| 4 | 伴有脑肿胀的大脑和小脑梗死的管理推荐意见美国心脏协会/美国卒中协会对医疗专业人员的声明显示文摘背景和目的关于缺血性卒中后脑肿胀患者的最佳管理方案,仍有许多尚未确定的问题。需要制定相关指南来指导如何处理这种严重并发症,如何提供最佳的综合性神经科和内科治疗,以及在患者病情恶化时如何与面临外科干预复杂决策的家属进行良好的沟通。本科学声明为大脑或小脑半球缺血性卒中伴脑肿胀的患者提供了早期的管理方案。方法写作组利用系统文献综述,参考公开发表的临床和流行病学研究、发病率和死亡率报告、临床与公共卫生指南、权威声明、个人文件以及专家意见,对现有证据进行总结并指出与当前知识水平的差距。写作组通过对MEDLINE、EMBASE和Web of Science数据库进行医学文献计算机检索(最后检索时间为2013年3月,研究对象为成年人)回顾最相关的文献。在美国心脏协会(American Heart Association,ARIA)框架背景下对证据进行组织,根据AHA/美国心脏病学学会基金会以及AHA卒中委员会的证据强度分级方案进行分类。这份声明经过AHA内部的广泛同行评议。结果已有适用于由缺血性梗死引起的半球(累及整个大脑中动脉供血区或更大范围)和小脑(累及小脑后下动脉或小脑上动脉供血区)肿胀的临床标准。幕上半球缺血性卒中伴脑肿胀发生恶化的临床表现包括新发意识障碍或意识障碍加重、脑性上睑下垂以及瞳孔大小变化。在小脑梗死伴肿胀患者中,意识水平下降是脑干受压的结果,因此可能出现早期角膜反射丧失和瞳孔缩小。应制定标准化定义以促进多中心和基于人群的发病率、患病率、危险因素和转归研究。脑肿胀高危患者的识别应包括临床和神经影像学资料。如果大面积卒中患者有必要进入全面复苏状态,则需要收入具备神经监护功能的病房。这些患者最好被收入由技术熟练和经验丰富的医生(如神经重症监护医生或神经血管科医生)负责的重症监护室或卒中单元。综合性医疗管理包括气道管理和机械通气、血压控制、液体管理以及血糖和体温控制。在幕上半球缺血性卒中伴肿胀患者中,不需行常规颅内压监测或脑脊液引流,但神经功能继续恶化的患者应考虑行去骨瓣减压和硬脑膜切开术。去骨瓣减压术在≥60岁的患者中的疗效尚不确定。在神经功能恶化的小脑卒中伴肿胀患者中,应行枕骨下颅骨切除和硬脑膜切开术。当应用脑室造瘘术缓解小脑梗死后梗阻性脑积水时,应同时行枕骨下颅骨切除术以防小脑向上移位导致的病情恶化。幕上半球梗死伴肿胀患者可获得令人满意的转归,但即使行去骨瓣减压术,仍有1/3的患者会遗留严重残疾和完全生活依赖。多数小脑梗死患者在术后能获得可接受的功能转归。结论大脑和小脑梗死伴肿胀是需要立即给予专业神经重症监护、并常需要进行神经外科干预的危重情况。去骨瓣减压术是很多患者的必然治疗选择,经过选择的患者能从中受益匪浅,尽管他们可能会遗留残疾,但仍可生活自理。 | Eelco F. M. Wijdicks Kevin N. Sheth Bob S. Carter David M. Greer Scott E. Kasner W. Taylor Kimberly Stefan Schwab Eric E. Smith Rafael J. Tamargo Max Wintermark 王玉琴 牛牧 柯开富 | 2014 | 国际脑血管病杂志2014，22，4： | 11 |
| 5 | Significant association between ABO blood group and pancreatic cancer显示文摘AIM:To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS:Using the University of Pittsburgh's clinicalpancreatic cancer registry,the blood donor database from our local blood bank (Central Blood Bank),and the blood product recipient database from the regional transfusion service (Centralized Transfusion Service) in Pittsburgh,Pennsylvania,we identified 274 pancreatic cancer patients with previously determined serological ABO blood group information.The ABO blood group frequency was compared between these patients and 708842 individual,community-based blood donors who had made donations to Pittsburgh's Central Blood Bank between 1979 and 2009.RESULTS:The frequency of blood group A was statistically significantly higher amongst pancreatic cancer patients compared to its frequency amongst the regional blood donors [47.63% vs 39.10%,odds ratio (OR)=1.43,P=0.004].Conversely,the frequency of blood group O was significantly lower amongst pancreatic cancer patients relative to the community blood donors (32.12% vs 43.99%,OR=0.60,P=0.00007).There were limited blood group B (n=38) and AB (n=17) pancreatic cancer patients;the overall P trend value comparing patient to donor blood groups was 0.001.CONCLUSION:The ABO blood group is associated with pancreatic cancer risk.Future studies should examine the mechanism linking pancreatic cancer risk to ABO blood group. | Julia B Greer Mark H Yazer Jay S Raval M Michael Barmada Randall E Brand David C Whitcomb | 2010 | World Journal of Gastroenterology2010，16，44： | 10 |
| 6 | Association between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population:Role of serine protease inhibitor Kazal 1type and alcohol显示文摘AIM: To test the hypothesis that calcium sensing receptor (CASR) polymorphisms are associated with chronic pancreatitis (CP), and to determine whether serine protease inhibitor Kazal 1type (SPINK1) N34S oralcohol are necessary co-factors in its etiology. METHODS: Initially, 115 subjects with pancreatitis and 66 controls were evaluated, of whom 57 patients and 21 controls were predetermined to carry the high-risk SPINK1 N34S polymorphism. We sequenced CASR gene exons 2, 3, 4, 5 and 7, areas containing the majority of reported polymorphisms and novel mutations. Based on the initial results, we added 223 patients and 239 controls to analyze three common nonsynonymous single nucleotide polymorphisms (SNPs) in exon 7 (A986S, R990G, and Q1011E). RESULTS: The CASR exon 7 R990G polymorphism was signifi cantly associated with CP (OR, 2.01; 95% CI, 1.12-3.59; P = 0.015). The association between CASR R990G and CP was stronger in subjects who reported moderate or heavy alcohol consumption (OR, 3.12; 95% CI, 1.14-9.13; P = 0.018). There was no association between the various CASR genotypes and SPINK1 N34S in pancreatitis. None of the novel CASR polymorphisms reported from Germany and India was detected. CONCLUSION: Our United States-based study confirmed an association of CASR and CP and for the first time demonstrated that CASR R990G is a signifi cant risk factor for CP. We also conclude that the risk of CP with CASR R990G is increased in subjects with moderate to heavy alcohol consumption. | Venkata Muddana Janette Lamb Julia B Greer Beth Elinoff Robert H Hawes Peter B Cotton Michelle A Anderson Randall E Brand Adam Slivka David C Whitcomb | 2008 | World Journal of Gastroenterology2008，14，28： | 7 |
| 7 | 环境信息公开的实践及启示显示文摘国内外环境信息公开现状
20世纪90年代初,特别是联合国环发大会以来,可持续发展成为国际社会环境与发展领域的一个主流。受其影响,环境保护在世界范围内出现了重要发展机会:强调扩大公众参与,倡导企业与公众采取环境保护的自觉行动,倡导政府和企业在环境保护方面建立伙伴关系。 | 王华 Linda Greer 蔺梓馨 | 2008 | 世界环境2008，，5： | 4 |
| 8 | 非传统晶体生长的早期观察显示文摘晶体早期生长的研究揭示,在某些体系中,晶体生长可能并不遵循传统路径.借由某些聚合物或生物分子的帮助,无机晶体的前驱体或纳米晶体在生长初期有可能聚集为无序的大块颗粒.这些聚集体表面晶化形成高结晶度高密度的外壳,随后完成从表面到核心的晶化过程.此逆向晶体生长机理在一些诸如沸石、钙钛矿、金属和金属氧化物等无机化合物体系中均已被发现,在其他材料体系里也将得到验证.认识这一新的晶体生长路径将给予我们更多的自由度来实现晶体形态控制,也有助于我们对于许多天然矿物形成机制的理解.本文简要回顾了最近本领域研究中一些典型逆向晶体生长的例子. | GREER Heather F 于丰娇 周午纵 | 2012 | 中国科学:化学2012，42，1： | 3 |
| 9 | Early stages of non-classic crystal growth显示文摘Investigation of early stages of crystal growth revealed that crystal growth in some systems may not follow the classic route.In the early stages of inorganic crystal growth,precursor molecules and/or nanocrystallites may aggregate into large and disordered particles with the assistance of some polymers or biomolecules.Surface crystallization of these aggregates would then take place to form shells with high crystallinity and density,followed by an extension of the crystallization from surface to core.This so-called reversed crystal growth mechanism has been found in crystallization of several inorganic compounds including zeolites,perovskites,metals and metal oxides,and will be identified in more material systems.The establishment of this new crystal growth route gave us more freedom to control the morphology of crystals and to understand the formation mechanism of many natural minerals.This article gives a brief review of the recent research in this field by featuring some typical examples of the reversed crystal growth. | GREER Heather F. | 2011 | Science China Chemistry2011，54，12： | 3 |
| 10 | Mutation of C. elegans demethylase spr-5 extends transgenerational longevity显示文摘象长寿那样的复杂 organismal 性质能被非基因的因素越过代播送。这里,我们表明 C 的那删除。elegans histone H3 离氨酸 4 dimethyl (H3K4me2 ) demethylase, spr-5,在 lifespan 引起 trans 辈份的增加。我们识别一个修改染色质的网络,它调整这 lifespan 扩展。我们进一步证明这 trans 辈份的 lifespan 延期依赖于包含类固醇 dafachronic 酸的一条神经质的发信号小径,原子受体 DAF-12 的使活跃之物。这些调查结果建议 demethylase SPR-5 的损失引起 H3K4me2 表明小径的已知的调整 lifespan 的 mis 规定和激活,导致 trans 辈份的 lifespan 扩展。 | Eric Lieberman Greer Ben Becker Christian Latza Adam Antebi Yang Shi | 2016 | Cell Research2016，26，2： | 3 |
| 11 | 温度对猕猴桃(Actinidia delicisa)光抑制及复原的影响显示文摘 | Greer,HD 欧阳龙 | 1989 | 农业科技译丛(湖南)1989，，4： | 2 |
| 12 | Deformation of plastically compressible hardening-softening-hardening solids显示文摘Motivated by a model of the response of vertically aligned carbon nanotube (VACNT) pillars in uniaxial compression, we consider the deformation of a class of compressible elastic-viscoplastic solids with a hardening-softening-hardening variation of flow strength with plastic strain. In previous work (Hutchens et al. 2011) a constitutive relation was presented and used to model the response of VACNT pillars in axisymmetric compression. Subsequently, it was found that due to a programming error the constitutive relation presented in the paper (Hutchens et al. 2011) was not the one actually implemented. In particular, the plastic flow rule actually used did not satisfy plastic normality. Here, we present the constitutive formulation actually implemented in the previous work (Hutchens et al. 2011). Dynamic, finite deformation, finite element calculations are carried out for uniaxial compression, uniaxial tension and for indentation of a 'half-space' by a conical indenter tip. A sequential buckling-like deformation mode is found in com- pression when there is plastic non-normality and hardening-softening-hardening. The same material characterization gives rise to a Lüders band-like deformation mode in ten- sion. When there is a deformation mode with a sharp front along mesh boundaries, the overall stress-strain response contains high frequency oscillations that are a mesh artifact. The responses of non-softening solids are also analyzed and their overall stress-strain behavior and deformationmodes are compared with those of hardening-softening- hardening solids. We find that indentation with a sharp in- denter tip gives a qualitatively equivalent response for hardening and hardening-softening-hardening solids. | A. Needleman S. B. Hutchens N. Mohan J. R. Greer | 2012 | Acta Mechanica Sinica2012，28，4： | 2 |
| 13 | Cold-temperature deformation of nano-sized tungsten and niobium as revealed by in-situ nano-mechanical experiments显示文摘We constructed and developed an in-situ cryogenic nanomechanical system to study small-scale mechanical behavior of materials at low temperatures.Uniaxial compression of two body-centered-cubic(bcc)metals,Nb and W,with diameters between400 and 1300 nm,was studied at room temperature and at 165 K.Experiments were conducted inside of a Scanning Electron Microscope(SEM)equipped with a nanomechanical module,with simultaneous cooling of sample and diamond tip.Stress-strain data at 165 K exhibited higher yield strengths and more extensive strain bursts on average,as compared to those at 298 K.We discuss these differences in the framework of nano-sized plasticity and intrinsic lattice resistance.Dislocation dynamics simulations with surface-controlled dislocation multiplication were used to gain insight into size and temperature effects on deformation of nano-sized bcc metals. | LEE Seok-Woo CHENG YinTong RYU Ill GREER Julia R. | 2014 | Science China(Technological Sciences)2014，57，4： | 2 |
| 14 | 成人脑死亡判定的循证医学指南更新--美国神经病学会质量标准分会报告显示文摘目的就如下问题对美国神经病学会1995年脑死亡判定实践标准进行更新:①符合脑死亡临床判定标准的患者神经功能能恢复吗?②确定患者神经功能永久性停止的恰当观察时间是多长?③有时可能观察到脑死亡患者的复合肢体运动,这是否错误地提示仍然保留脑功能?④何种技术手段判断呼吸停止是相对安全的?⑤是否存在新的辅助检测能准确判断患者脑死亡?方法系统回顾MEDLINE及EMBASE数据库1996年1月—2009年5月收录的文献,其研究仅限于成年人(≥18岁)。结果及建议对成年人,按照美国神经病学会于1995年确定的脑死亡判定实践标准,目前尚无判定为脑死亡患者出现神经功能恢复的报告。脑死亡患者可以存在复合的自发运动及假阳性触发呼吸机。目前还无足够的证据用以确定神经功能不可逆性停止的最短观察时间。通过氧扩散来确定呼吸停止是安全的,但目前还无足够证据确定呼吸停止检测技术的相对安全性。目前还无足够的证据确定新型辅助检测能否准确判断患者全脑功能已经停止。 | Wijdicks EFM Varelas PN Gronseth GS Greer DM 王宁(译) 何福亮(译) | 2010 | 中国脑血管病杂志2010，7，9： | 2 |
| 15 | Regulation of adiposity by dietary calcium显示文摘 | ZEMEL M B SHI H GREER B | 2000 | FASEB Journal2000，14，： | 2 |
| 16 | The effect of unethical behavior on trust in a buyer–supplier relationship: The mediating role of psychological contract violation显示文摘 | James A. Hill Stephanie Eckerd Darryl Wilson Bertie Greer | 2008 | Journal of Operations Management2008，，4： | 2 |
| 17 | Lactic acid inhibition of the growth of spoilage bacteria and cold tolerant pathogens on pork 显示文摘 | GREER G G DILTS B D | 1995 | Int J Food Microb1995，25，： | 1 |
| 18 | Feeding the premature infant in the 20th Century显示文摘 | Greer FR | 2001 | J Nutr2001，131，2： | 1 |
| 19 | Autopathogenic T Helper Cell Type 1 (Thl) and Protective Th2 Clones Differ in Their Recognition of the Autoantigenic Peptide of Myelin Proteolipid Protein 显示文摘 | Mercy PD Lindsay BN Greer JM | 1997 | J Exp Med1997，186，6： | 1 |
| 20 | The generic relationships of the scincid liz- ard genus Leiolopisma and its relatives 显示文摘 | GREER A E | 1974 | Australian Journal of Zoology Supplemental Series1974，22，31： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员