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A simple,water-soluble,Fe^(3+)-selective fluorescent probe and its application in bioimaging

查看全文 作  者:Xiao-Hang [1]Yang;Shu [1]Li;Zhi-Shu [1]Tang;Xi-Di [2]Yu;Tin [2]Huang;Yong [2,3]Gao 高影响力作者 机构地区:[1]Medical Technology Department.Shaanxi College of Traditional Chinese Medicine;[2]College of Chemistry and Chemical Engineering,Fujian Normal University;[3]State Key Laboratory of Fine Chemicals,Dalian University of Technology高影响力机构 出  处:《Chinese Chemical Letters》索引2015年第26卷第1期,共4页高影响力期刊 基  金:supported by Natural Science Foundation of Fujian Province(No.2013H0019);the Science Foundation of Education Department of Fujian Province(No.JA11064);the Open Foundation of the State Key Laboratory of Fine Chemicals(No.KF1307);the Open Foundation of Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecular Chemistry 摘  要:A simple,water-soluble,Fe^(3+)-selective fluorescent probe,derived from rhodamine B,was synthesized and characterized.The probe exhibits a fluorescence response toward Fe^(3+) with acceptable sensitivity and selectivity and even facilitates visual or naked-eye detection of Fe^(3+).The experiment results show that the response of the probe to Fe^(3+) is pH-independent over a wide range of 4.0-10.0.In addition,fluorescence microscopic imaging experiments have proven that the probe is cell permeable and can be used for monitoring intracellular Fe^(3+) in living cells. 关 键 词:Fluorescent probe Ferric ion Aqueous solution Fluorescent imaging
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