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| 1 | ROC曲线中最佳工作点的选择显示文摘 | 陈卫中 潘晓平 宋兴勃 倪宗瓒 | 2006 | 中国卫生统计2006，23，2： | 95 |
| 2 | GPS PPP技术用于滑坡监测的试验与结果分析显示文摘为了研究全球定位系统(GPS)精密单点定位(PPP)技术用于滑坡等地质灾害监测时可能达到的精度和可靠性等问题,结合某类滑坡的大型物理模型试验,在滑坡体上布设了若干GPS监测点进行连续实时动态监测,利用PPP技术对该滑坡从稳定、开始滑动直至产生破坏的全过程监测数据进行了处理与分析,并与GPS单历元差分定位、载波相位实时差分定位技术监测结果进行了对比。结果表明:GPS PPP技术监测结果的内符合精度约为10 mm,外符合精度约为40 mm,且GPS PPP技术具有一些差分GPS无法比拟的优势,如无需基准站支持、作业成本低、效率高、可直接获取监测点在国际地球参考框架下的绝对坐标等。该技术完全可用于滑坡等地质灾害的实时动态监测和预警。 | 王利 张勤 黄观文 涂锐 张双成 | 2014 | 岩土力学2014，35，7： | 31 |
| 3 | ON THE EXISTENCE OF POSITIVE SOLUTIONS TO SECOND ORDER PERIODIC BVPS显示文摘The existence of positive solutions to second-order periodic BVPs-u'+Mu =j(t, u),t(0) = u(2π),u’(0) = '(2π) and u'+ Mu = I(t, u), u(0) = u(2π), u’(0) = u’(2π)is proved by a simple appliCation of a Fixed point Theorem in cones due to Krasnoselskii. | 蒋达清 | 1998 | Acta Mathematica Scientia1998，18，S1： | 28 |
| 4 | Third-order point contact approach for five-axis sculptured surface machining using non-ball-end tools (Ⅰ): Third-order approximation of tool envelope surface显示文摘In this paper, the geometric properties of a pair of line contact surfaces are investigated. Then, based on the observation that the cutter envelope surface contacts with the cutter surface and design surface along the characteristic curve and cutter contact (CC) path, respectively, a mathematical model describing the third-order approximation of the cutter envelope surface according to just one given cutter location (CL) is developed. It is shown that at the CC point both the normal curvature of the normal section of the cutter envelope surface and its derivative with respect to the arc length of the normal section can be determined by those of the cutter surface and design surface. This model characterizes the intrinsic relationship among the cutter surface, cutter envelope surface and design surface in the neighborhood of the CC point, and yields the mathematical foundation for optimally approximating the cutter envelope surface to the design surface by adjusting the cutter location. | ZHU LiMin1, DING Han2 & XIONG YouLun2 1 State Key Laboratory of Mechanical System and Vibration, Shanghai Jiao Tong University, Shanghai 200240, China 2 State Key Laboratory of Digital Manufacturing Equipment and Technology, Huazhong University of Science and Technology, Wuhan 430074, China | 2010 | Science China(Technological Sciences)2010，53，7： | 25 |
| 5 | Third-order point contact approach for five-axis sculptured surface machining using non-ball-end tools(II): Tool positioning strategy显示文摘Based on the mathematical model describing the third-order approximation of the cutter envelope surface according to one given cutter location(CL),a tool positioning strategy is proposed for efficiently machining free-form surfaces with non-ball-end cutters.The optimal CL is obtained by adjusting the inclination and tilt angles of the cutter until its envelope surface and the design surface have the third-order contact at the cutter contact(CC)point,which results in a wide machining strip.The strategy can handle the constraints of machine joint angle limits,global collision avoidance and tool path smoothness in a nature way,and can be applied to general rotary cutters and complex surfaces.Numerical examples demonstrate that the third-order point contact approach can improve the machining strip width greatly as compared with the recently reported second-order one. | ZHU LiMin 1 ,DING Han 2 &XIONG YouLun 2 1State Key Laboratory of Mechanical System and Vibration,Shanghai Jiao Tong University,Shanghai 200240,China 2State Key Laboratory of Digital Manufacturing Equipment and Technology,Huazhong University of Science and Technology,Wuhan 430074, China | 2010 | Science China(Technological Sciences)2010，53，8： | 23 |
| 6 | 平均学分绩点计算方法比较与选择显示文摘目前我国大学普遍实行学分制。学分制是以选课为基础,以学分为单位计算学生的学习量,以平均学分绩点(General Point Average,即GPA)为尺度衡量学生的学业成绩的一种教学管理制度。分析和比较不同大学学分制管理工作的实际情况,我们发现,不同大学选课和课程学分计算的差异不大,比如采用计算机信息系统选课、大约16个学时计1个学分等,但是,在平均学分绩点的计算方法及结果使用方面,则存在明显的差异。 | 刘卫萍 | 2008 | 当代教育论坛(学科教育研究)2008，，7： | 21 |
| 7 | Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21显示文摘Background:Epidermal growth factor receptor(EGFR) mutations,including a known exon 19 deletion(19 del) and exon 21 L858 R point mutation(L858R mutation),are strong predictors of the response to EGFR tyrosine kinase inhibitor(EGFR-TKI) treatment in lung adenocarcinoma.However,whether patients carrying EGFR 19 del and L858 R mutations exhibit different responsiveness to EGFR-TKls and what are the potential mechanism for this difference remain controversial.This study aimed to investigate the clinical outcomes of EGFR-TKI treatment in patients with EGFR 19 del and L858 R mutations and explore the genetic heterogeneity of tumors with the two mutation subtypes.Methods:Of 1127 patients with advanced lung adenocarcinoma harboring EGFR 19 del or L858 R mutations,532 received EGFR-TKI treatment and were included in this study.EGFR 19 del and L858 R mutations were detected by using denaturing high-performance liquid chromatography(DHPLC).T790 M mutation,which is a common resistant mutation on exon 20 of EGFR,was detected by amplification refractory mutation system(ARMS).Next-generation sequencing(NGS) was used to explore the genetic heterogeneity of tumors with EGFR 19 del and L858 R mutations.Results:Of the 532 patients,319(60.0%) had EGFR 19 del,and 213(40.0%) had L858 R mutations.The patients with EGFR 19 del presented a significantly higher overall response rate(ORR) for EGFR-TKI treatment(55.2%vs.43.7%,P = 0.017) and had a longer progression-free survival(PFS) after first-line EGFR-TKI treatment(14.4 vs.11.4 months,P = 0.034) compared with those with L858 R mutations.However,no statistically significant difference in overall survival(OS) was observed between the two groups of patients.T790 M mutation status was analyzed in 88 patients before EGFR-TKI treatment and 134 after EGFR-TKI treatment,and there was no significant difference in the co-existence of T790 M mutation with EGFR 19 del and L858 R mutations before EGFR-TKI treatment(5.6%vs.8.8%,P = 0.554)or after treatment(24.4%vs.35.4%,P = 0.176).In addition,24 patients with EGFR 19 del and 19 with L858 R mutations were analyzed by NGS,and no significant difference in the presence of multiple somatic mutations was observed between the two genotypes.Conclusions:Patients with EGFR 19 del exhibit longer PFS and higher ORR compared with those with L858 R mutations.Whether the heterogeneity of tumors with EGFR 19 del and L858 R mutations contribute to a therapeutic response difference needs further investigation. | Jiang-Yong Yu Si-Fan Yu Shu-Hang Wang Hua Bai Jun Zhao Tong-Tong An Jian-Chun Duan Jie Wang | 2016 | Chinese Journal of Cancer2016，35，4： | 19 |
| 8 | Influence of obstacle disturbance in a duct on explosion characteristics of coal gas显示文摘In combination with experimental research,numerical simulation is performed to investigate the influence law of the obstacles in a duct on the explosion flame of premixed coal gas and air. The numerical method uses upwind WENO scheme and two-step chemical reaction model. The interaction mechanism is addressed between the compression wave from reflection on the right end of the duct and flame propagation. The reflected wave is found to result in the decrease of flame velocity. On this basis,we analyze the mechanism of the obstacles on flame as well as the law of flow field variation thus caused. The results suggest that,due to the obstacles,deflagration wave is repeatedly reflected,combustible gas mixture is fully compressed,temperature and pressure rise,chemical reaction speed increases,and hence flame intensity is strengthened. At the same time,a tripe point forms as a result of wall reflection of the deflagration wave from the obstacles and furthermore local flame speed increases. As the triple point propagates forward,the flame speed gradually decreases due to dissipation of energy. These conclusions provide a valuable theoretical foundation for the prediction of explosion field,prevention of fire and explosion and effective control of the com-bustion speed and flame propagation speed in detonation propulsion. | WANG Cheng1,MA TianBao1 & LU Jie2 1 State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology,Beijing 100081,China 2 Taiyuan Gas Company,Taiyuan 030024,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，2： | 16 |
| 9 | Finite element method based on combination of 'saddle point' variational formulations显示文摘A modified mixed/hybrid finite element method, which is no longer required to satisfy the Babuska-Brezzi condition, is referred to as a stabilized method Based on the duality of vanational principles in solid mechanics, a new type of stabilized method, called the combinatorially stabilized mixed/hybrid finite element method, is presented by weight-averaging both the primal and the dual 'saddle-point' schemes. Through a general analysis of stability and convergence under an abstract framework, it is shown that for the methods only an inf-sup inequality much weaker than Babuska-Brezzi condition needs to be satisfied. As a concrete application, it is concluded that the combinatorially stabilized Raviart and Thomas mixed methods permit the C -elements to replace the H(div; Ω)-elements. | 周天孝 | 1997 | Science China(Technological Sciences)1997，40，3： | 16 |
| 10 | 多媒体课件设计制作模式研究显示文摘研究多媒体课件制作的基本模式,对于指导教师制作课件,进行信息化教学具有重要意义。应在实践经验的基础上,针对课件实际设计过程中遇到的主要问题,构建立足于需求分析基础之上的问题解决式课件设计制作的生命周期模型,分析课件设计制作的主要环节,即需求分析、教学模式选择、总体结构设计、完善和体验。 | 聂钢 韩静静 | 2005 | 教育探索2005，，1： | 15 |
| 11 | 连续性业务系统中容灾备份系统的建设显示文摘对于业务连续性要求较高的系统,采用容灾系统实现数据保护和信息系统业务连续性保护已显得越来越重要。文章介绍了杭州市劳动信息系统的业务连续性特点以及建设容灾备份系统的背景;提出了容灾备份系统建设的具体目标;通过对当前有关容灾备份系统建设的技术分析,提出了杭州市劳动信息系统容灾备份系统建设方案;分析了方案的局限性,并对系统进一步发挥作用提出了建议。 | 陈开艺 | 2007 | 计算机时代2007，，11： | 15 |
| 12 | Hierarchy modeling of subsurface palaeochannel reservoir architecture显示文摘The studies on fluvial reservoir architecture are mainly aimed at outcrop and modern deposition,but rarely at the subsurface reservoir,so there are few effective methods to predict the distribution of subsurface reservoir architectures. In this paper,taking the meandering river reservoir of Guantao formation Gudao Oilfield,Jiyang depression,Baohai Gulf Basin,East China as an example,the archi-tectural modeling method of complex meandering belt reservoir is proposed,that is hierarchy con-straint,pattern fitting and multi-dimensional interaction. Architectures of meandering river reservoir can be divided into three hierarchies: meandering channel sandbody,point bar and lateral accretion body. Different hierarchies of the quantitative architecture pattern are fitted to subsurface well data (including dynamic monitoring data) in different hierarchies through one-dimensional hole,2D profiles and plane and 3D space,which are verified by each other. And then 3D model in different hierarchies is established. At the same time,the quantificational relationship between width of active river and the scale of point bar is set up,and the scale of lateral accretion sand body and shale beddings is con-firmed with horizontal well data. The study not only has significant meaning on the development of geology,but also can improve the oilfield exploitation greatly. | WU ShengHe1,YUE DaLi1,LIU JianMin2,SHU QingLin2,FAN Zheng1,3 & LI YuPeng1 1 Earth Sciences and Geoinformatics School,China University of Petroleum,Beijing 102249,China 2 SINOPEC Shengli Oilfield Co. Ltd.,Dongying 257000,China 3 Beijing Telon High-tech Corporation,Beijing 100085,China | 2008 | Science China Earth Sciences2008，51，S2： | 15 |
| 13 | Boundary value problems of discrete generalized Emden-Fowler equation显示文摘By using the critical point theory, some sufficient conditions for the existence of the solutions to the boundary value problems of a discrete generalized Emden-Fowler equation are obtained. In a special case, a sharp condition is obtained for the existence of the boundary value problems of the above equation. For a linear case, by the discrete variational theory, a necessary and sufficient condition for the existence, uniqueness and multiplicity of the solutions is also established. | YU Jianshe GUO Zhiming | 2006 | Science China Mathematics2006，49，10： | 14 |
| 14 | 对润滑油降凝剂的认识显示文摘 | 邓广勇 包冬梅 刘红辉 李纯录 | 2010 | 润滑油2010，25，6： | 14 |
| 15 | A SCALED CENTRAL PATH FOR LINEAR PROGRAMMING显示文摘Interior point methods are very efficient methods for solving large scale linear programming problems. The central path plays a very important role in interior point methods. In this paper we propose a new central path, which scales the variables. Thus it has the advantage of forcing the path to have roughly the same distance from each active constraint boundary near the solution. | Ya-xiang Yuan (State Key Laboratory of Scientific and Engineering Computing, Institute of Computational Mathematics and Scientific/Engineering Computing Chinese Academy of Sciences, Beijing 100080, China) | 2001 | Journal of Computational Mathematics2001，19，1： | 14 |
| 16 | Existence,uniqueness and stability of C^m solutions of iterative functional equations显示文摘In this paper we discuss a relatively general kind of iterative functional equation G( x, f( x),… , fn(x)) = 0 (for all x∈J), where J is a connected closed subset of the real number axis R, G∈ Cm( Jn+1, R), and n≥2. Using the method of approximating fixed points by small shift of maps, choosing suitable metrics on functional spaces and finding a relation between uniqueness and stability of fixed points of maps of general spaces, we prove the existence, uniqueness and stability of Cm solutions of the above equation for any integer m≥0 under relatively weak conditions, and generalize related results in reference in different aspects. | 麦结华 刘新和 | 2000 | Science China Mathematics2000，43，9： | 14 |
| 17 | 浮针治疗慢性咳嗽20例显示文摘慢性咳嗽的病因很多,常常是患者来门诊就诊的主因。浮针疗法是针对肌肉的肌筋膜触发点(myofascial trigger point, MTrP)。进行治疗,使肌肉放松,改善血供,达到治疗疼痛的目的。咳嗽是因为气道受刺激引起咽肌、声门、膈肌及其他呼吸肌的收缩而产生, | 吕中广 | 2010 | 中国针灸2010，30，1： | 13 |
| 18 | Analysis of EET on Ca increasing the melting point of Mg_(17)Al_(12) phase显示文摘The present investigation showed that the additions of Ca to the alloy AZ91 were mainly dissolved into the Mg17Al12 phase and increased its melting point and thermal stability, which would have great effects on the high-temperature properties of AZ91 alloy. The empirical electron theory (EET) of solid and molecules was used to calculate the valence electron structures (VES) of Mg17Al12 intermetallic compound with and without Ca addition. The results showed that Ca dissolving in Mg17Al12 phase increased the strength of bonds that control the thermal stability of Mg17Al12 phase. Additions of Ca also made the distribution of the valence electrons on the dominant bond network more uniform in the whole unit cell of Mg17Al12. The theoretical conclusions well account for the experimental results. | MIN Xuegang, DU Wenwen, XUE Feng & SUN YangshanDepartment of Material Science and Engineering, Southeast University, Nanjing 210096, China | 2002 | Chinese Science Bulletin2002，47，13： | 13 |
| 19 | A NEW APPROACH FOR THE SOLUTION OF SINGULAR OPTIMUM IN STRUCTURAL TOPOLOGY OPTIMIZATION显示文摘In order to overcome the difficulties caused by singular optima,inthe present paper,a new method for the solutions of structural topology optimizationproblems is proposed.The distinctive feature of this method is that instead of solv-ing the original optimization problem directly,we turn to seeking the solutions of asequence of approximated problems which are formulated by relaxing the constraintsof the original problem to some extent.The approximated problem can be solvedefficiently by employing the algorithms developed for sizing optimization problemsbecause its solution is not singular.It can also be proved that when the relaxationparameter is tending to zero,the solution of the approximated problem will convergeto the solution of the original problem uniformly.Numerical examples illustrate theeffectiveness and validity of the present approach.Results are also compared withthose obtained by traditional methods. | 郭旭 程耿东 | 1997 | Acta Mechanica Sinica1997，13，2： | 13 |
| 20 | 基于空间句法和POI信息的城市商业网点布局研究——以成都市龙泉驿区为例显示文摘首先运用空间句法的原理,计算出龙泉驿区路网的形态变量,依此可分析出路网的空间可达性。然后运用大数据的思想,从网上提取购物、餐饮、生活服务类POI信息,反映出这些类型商业网点的空间集聚规律。最后分析不同类型商业网点集聚的街道与路网空间可达性的关系,从而为后期商业网点布局提供参考。 | 周垠 张诚 崔铭 李楠 陈鹏 | 2014 | 四川建筑2014，34，6： | 12 |
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