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| 1 | Integration of meta-QTL discovery with omics: Towards a molecular breeding platform for improving wheat resistance to Fusarium head blight显示文摘Fusarium head blight(FHB) is a global wheat disease that devastates wheat production. Resistance to FHB spread within a wheat spike(type Ⅱ resistance) and to mycotoxin accumulation in infected kernel(type Ⅲ resistance) are the two main types of resistance. Of hundreds of QTL that have been reported, only a few can be used in wheat breeding because most show minor and/or inconsistent effects in different genetic backgrounds. We describe a new strategy for identifying robust and reliable meta-QTL(mQTL)that can be used for improvement of wheat FHB resistance. It involves integration of mQTL analysis with mQTL physical mapping and identification of single-copy markers and candidate genes. Using metaanalysis, we consolidated 625 original QTL from 113 publications into 118 genetic map-based mQTL(gmQTL). These gmQTL were further located on the Chinese Spring reference sequence map. Finally, 77 high-confidence mQTL(hcmQTL) were selected from the reference sequence-based mQTL(smQTL).Locus-specific single nucleotide polymorphism(SNP) and simple sequence repeat(SSR) markers and17 genes responsive to FHB were then identified in the hcmQTL intervals by combined analysis of transcriptomic and proteomic data. This work may lead to a comprehensive molecular breeding platform for improving wheat resistance to FHB. | Tong Zheng Chen Hua Lei Li Zhengxi Sun Minmin Yuan Guihua Bai Gavin Humphreys Tao Li | 2021 | The Crop Journal2021，9，4： | 4 |
| 2 | Breeding new cultivars for sustainable wheat production显示文摘Common wheat(Triticum aestivumL.)is amajor staple food crop that feeds about 40% of the world’s population.Wheat production and utilization accounts for^28% of the global cereal crops(http://gffzz4d9321d972ec49cehxbq0bpvbpnnp6kww.ffgz.tsg.suse.edu.cn/)food-outlookbiannual-report-global-food-markets.Consequently,wheat supplies approximately one-fifth of human calories in a variety of forms,including leavened,flat and steamed breads,biscuits,cakes,different forms of noodles,pasta,couscous,and pies,as well as secondary products such as starch,gluten and nonflour milling fractions.Wheat consumption has been steadily increasing due to population expansion and urbanization.For example,wheat consumed in China increased more than sixfold(from 19 million tons to 123 million tons)in the 50 years from 1962 to 2012[1]. | Hongjie Li Timothy D.Murray Robert A.McIntosh Yang Zhou | 2019 | The Crop Journal2019，7，6： | 1 |
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