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1Metal-Metal Cooperation in Dinucleating Complexes Involving Late Transition Metals Directed towards Organic Catalysis显示文摘Cooperatively bimetallic organic catalysis,coupling actions of two metal centers in a catalytic organic transformation via co-activation of a single molecule or synergistic activation of two molecules,has witnessed rapid development in the last decades.Ni Xiong Guoxiang Zhang Xiaolong Sun Rong Zeng 2020Chinese Journal of Chemistry2020,38,2:4
2The [4+2] Cycloaddition of 2-Pyrone in Total Synthesis显示文摘Diels-Alder reaction is one of the most important reactions in organic synthesis and has witnessed great achievements in total syntheses of complex natural products.In this review,we will focus on the [4+2] cycloaddition that utilizes 2-pyrone as the diene component.Major advances of its applications in the total syntheses of natural products in the past fifty years will be discussed here.Quan Cai 2019Chinese Journal of Chemistry2019,37,9:3
3Asymmetric Catalytic[3+2]Annulation of Donor-Acceptor Cyclopropane with Cyclic Ketones:Facile Access to Enantioenriched 1-Oxaspiro[4.5]decanes显示文摘of main observation and conclusion A copper catalyzed enantioselective[3+2]annulation of donor-acceptor cyclopropanes with cyclic ketones has been developed,providing a concise protocol to enantioenriched l-oxaspiro[4.5]decanes in up to 98%yield with up to>99/1 dr and up to 92%ee.In addition,this method also provides a facile access to the enantioselective desymmetrisation of various 4-substituted cyclohexanones.The resulting products were easily converted to the core structures of two natural products Heliespirones A and halogenated sesquiterpene isolated from L saitoi.Zhong-Bo Zheng Wen-Fu Cheng Lijia Wang Jun Zhu Xiu-Li Sun Yong Tang 2020Chinese Journal of Chemistry2020,38,12:1
4Z-bpy,a New C2-Symmetric Bipyridine Ligand and Its Application in Enantioselective Copper(Ⅰ)-Catalyzed Cyclopropanation of Olefins显示文摘Summary of main observation and conclusion A rigid C2-symmetric chiral bipyridine ligand Z-bpy with a triptycene-like backbone was designed and synthesized from simple chemicals in a scalable route.Using this new ligand,copper(Ⅰ) catalyzed cyclopropanation of styrenes with commercial ethyl diazoacetate produced various corresponding cyclopropanes in high yields,diastereoselectivity and enantioselectivity up to 97% ee.Yizhao Ouyang Miao Zhan Jing Zhou Jiao Jiao Hao HU Yoichi M.A.Yamada Pengfei Li 2019Chinese Journal of Chemistry2019,37,8:1
5Iridium-Catalyzed Enantioselective C(sp^3)-H Borylation of Cyclobutanes显示文摘of main observation and conclusion We herein report the first example of iridium-catalyzed enantioselective C(sp^3)-H borylation of cyclobutanes using benzoxazoline as the directing group.The combination of a chiral bidentate boryl ligand and an iridium precursor has found to effectively catalyze C(sp)-H borylation to afford a variety of cyclobutylboronates with good to excellent enantioselectivities.We also demonstrate the synthetic utility of the current method by converting the stereogenic C—B bond to other functionalities.Xiang Chen Lili Chen Hongliang Zhao Qian Gao Zhenlu Shen Senmiao Xu 2020Chinese Journal of Chemistry2020,38,12:1
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