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		题名	作者	年代	出处	被引量
	1	内质网应激与糖尿病关系的研究进展显示文摘通过文献资料法对内质网应激与糖尿病的发生发展及治疗间的关系进行了综述,研究表明内质网应激通过非折叠蛋白反应和炎症等途径引起胰岛β细胞功能障碍和外周胰岛素抵抗,导致糖尿病的发生发展,内质网应激有可能作为糖尿病治疗的有效靶点。该综述为糖尿病的治疗提供了理论依据。	徐国琴孙涛吴丽萍	2018	转化医学电子杂志2018，5，1：	6
	2	Influence of edaravone on growth arrest and DNA damage-inducible protein 34 expression following focal cerebral ischemia-reperfusion in rats显示文摘Objective:To investigate the influence of edaravone on the expression of growth arrest and DNA damage-inducible protein 34(GADD34).Methods:A total of 108 healthy male Sprague-Dawlcy rats were randomly divided into sham operation group,model group and edaravone.group(36 cases for each group).Transient focal cerebral ischemia was induced by middle cerebral artery occlusion for 2 h followed by reperfusion in Sprague-Dawlev rats.Then.GAOD34 expression was measured with immunohistochemistry at different time-points after reperfusion in the peri-infarct regions of all rats.Results:The GADD34 expression was detected in the peri-infaret regions of rats 1 h after reperfusion,which reached its peak 24 h after reperfusion.And edaravone could significantly down-regulate the GAOD34 expression.Conclusions:Edaravon could down-regulate GADD34 expression,which suggests that edaravone may exert an important function in inhibiting endoplasmic reticulum stress reaction by scavenging free radicals in the upper stream.	Wei Wang Xiao-Mei Wu Bo Jiang Chun-Yu Wang Hai-Nan Zhang Xiang-Min Shen	2014	Asian Pacific Journal of Tropical Biomedicine2014，4，9：	0

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