| 1 | 慢性肾脏病并发高尿酸血症别嘌呤醇治疗的相关临床研究显示文摘目的 :探讨用别嘌呤醇治疗慢性肾功能衰竭并高尿酸血症以延缓慢性肾功能衰竭病程进展。方法 :收集2012年1月~2013年1月于我院诊治的80例慢性肾脏病并发高尿酸血症患者,随机分成治疗组和对照组,对照组行常规慢性肾功能衰竭治疗,治疗组在同样行常规慢性肾功能衰竭治疗的基础上,给予别嘌呤醇100-200mg/d,观察血清尿酸、肌酐、胱抑素C及尿素氮水平、血压指标。结果 :治疗组血清尿酸、肌酐、胱抑素C及尿素氮水平、血压较对照组低,肾功能恶化者较对照组明显减少。结论 :慢性肾功能衰竭并高尿酸血症,别嘌呤醇可有效降低尿酸水平,并能有效延缓慢性肾功能衰竭的进展。 | 田政湘 李泉清 张黎 | 2015 | 湖南师范大学学报(医学版)2015，12，5： | 10 |
| 2 | Correlation between blood lipids and serum uric acid in the elderly patients with coronary heart disease显示文摘Objective:To explore the relationship between blood lipids and serum uric acid(UA)in the elderly patients with coronary heart disease(CHD).Method:Quartered patients according to their uric acid level.Systematic review and compare lipid level among this four groups.Polynary logistic stepwise regression analysis were employed to analyze independent risk factor of coronary heart disease.Results:Serum level of triglycerides(TAG)and very low density lipoprotein cholesterol(VLDL-C)increase significantly(F=7.42,p<0.01;F=5.42,p<0.01 respectively)while high density lipoprotein cholesterol(HDL-C)and Apolipoprotein A1(Apo A1)decrease(F=5.03,p<0.01;F=7.03,p<0.01)upon elevated serum uric acid level among coronary heart disease patients.Gender(OR=0.16,95%CI 0.078~0.315,p=0.001),Ccr(OR=0.95,CI=0.935~0.969,p=0.001),associated hypertension(OR=2.23,CI=1.156~4.285,p=0.017)or DM(OR=2.44,CI=1.154~5.168,p=0.02),TC(OR=1.56,CI=1.119~2.186,p=0.009),HDL-C(OR=0.02,CI=0.004~0.076,p=0.001),UA(OR=1.09,1.086~1.094,p=0.001)are all independent risk factors for coronary heart disease.Conclusion:TAG,VLDL-C were positively related to UA while HDL-C and Apo A1were negatively linked to UA among CHD patients.Gender,Ccr,Hypertension,DM,TC,HDL-C and UA are independent risk factors for CHD while BMI,TAG,LDL-C were not. | Jie Geng Bin Yu Shu Tao Chen Qing Liang Chen Hong Liang Cong Bo Li Lin Wang | 2014 | 生物技术世界2014，11，11： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员