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| 1 | Influence of the extraction parameters on the cytotoxicity test results of Mg materials显示文摘Recently more and more researchers query the predictability of cytotoxicity results of biomedical Mg alloys obtained according to ISO 10993 due to significant difference between in vitro and in vivo corrosion. This study aimed to observe the influence of different extraction parameters(time, volume/surface ratio and medium composition) on cytotoxicity results and illustrate whether more predictable results could be obtained by adjusting the extraction parameters. The results showed that longer extraction time and smaller extraction volume/surface ratio improve the sensitivity of screening Mg materials by making inferior Mg materials release relatively more ions to the extract; and more predictable results could not be obtained by the way of simply adding bovine serum albumin(BSA) into the extraction medium to the same level in vivo or simply using fetal bovine serum(FBS) directly as extraction medium, since BSA and FBS accelerated the corrosion of Mg materials during extraction and they affected the cells' health states during the test. In order to get more predictable results, in our opinions, it is necessary to establish a database of primary cells' hazards(metal ions, p H and H2gas) tolerance and a set of in vitro corrosion test with high similarity in vivo, which is very difficult to realize now however. | Xiaoli Liu Tingfei Xi Yudong Zheng | 2014 | Progress in Natural Science:Materials International2014，24，5： | 1 |
| 2 | 镁合金AZ31表面含硅涂层在人工血浆中的降解行为显示文摘采用浸涂法在AZ31镁合金表面上制备了含硅涂层;采用浸泡腐蚀等方法研究了涂层在人工血浆溶液中的腐蚀速率和降解行为,利用电子探针(EPMA)测定涂层的表面形貌及化学成分,采用四唑盐(MTT)比色法测定了涂层的细胞毒性。结果表明,含硅涂层使AZ31镁合金在人工血浆中的腐蚀速率降低到一半,腐蚀程度降低,且含硅涂层无细胞毒性。这些结果对其作为血管支架材料有一定的实用意义。 | 李春梅 卫中领 吴森 周邦新 | 2014 | 腐蚀与防护2014，35，7： | 1 |
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