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1以表皮生长因子受体为靶点的脑肿瘤分子显像剂研究进展显示文摘表皮生长因子受体(epidermal growth factor receptor,EGFR)属酪氨酸激酶型受体,EGFR基因扩增、重排和突变导致的EGFR蛋白过度表达是原发性胶质母细胞瘤中最常见的遗传变异。目前,常规肿瘤分子病理学手段不能对无法获得标本的胶质瘤患者进行检测,而PET通过影像学手段检测病灶。根据EGFR生物化学特征,靶向EGFR的显像剂可分为核素标记的酪氨酸激酶抑制剂和核素标记的单克隆抗体。张慧玮 管一晖 2016肿瘤影像学2016,25,3:5
2Review of minimally invasive continuous glucose monitoring technology & instruments显示文摘Continuous blood glucose monitoring is important for the diagnosis,treatment,and study of diabetes. many organizations have been working on this subject in recent two decades. Glucose concentration in interstitial fluid is closely related to the blood glucose levels. Minimally invasive continuous blood glucose monitoring technology based on the glucose detection in interstitial fluid develops rapidly and gets more and more attentions from the patients and the doctors,due to its instantaneous real-time display of glucose level,'24/7'coverage,and the ability to characterize glycemic variability. According to the different detection methods,most of the continuous glucose monitoring technology could be divided into two kinds: subcutaneous implantation method and transdermal extraction method. This paper review s the recent development of minimally invasive blood glucose monitoring technology and instruments. The mainly remained challenges and related research directions are presented as well.YU Haixia LI Dachao XU Kexin 2016Instrumentation2016,3,4:2
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