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1Magnetic resonance cholangiopancreatography for the detection of pancreatic duct stones in patients with chronic pancreatitis显示文摘AIM:To assess the role of magnetic resonance cholangiopancreatography(MRCP) in detection of pancreatic duct stones(PDS) in patients with chronic pancreatitis(CP).METHODS:Clinical data of 78 CP patients who were treated at the First Affi liated Hospital of Xi'an Jiaotong University(China) between January 2004 and July 2008 were retrospectively analyzed.A predictive model of pancreatic duct stones was established through logistic regression and its effectiveness was verifi ed.Among these patients, MRCP was performed in 60 patients who served as a control group, while 44 patients with a higher predictive value than the entry threshold of the predictive model served as an experimental group.RESULTS:The positive rate of PDS in the 78 patients with CP was 19.2%(15/78).The predictive entry threshold of the predictive model was 5%(P < 0.05).The possibility of existence of PDS could be predicted according to the following 4 indexes:gastrointestinal symptoms, intermittent abdominal pain, diabetes mellitus(DM)/impaired glucose tolerance(IGT) and positive B-mode ultrasound results.The incidence of PDS in the experimental group was higher than that in the control group(P < 0.05).CONCLUSION:MRCP is strongly suggested for the detection of PDS in patients with gastrointestinal symptoms, intermittent abdominal pain, DM/IGT and positive B-mode ultrasound results.Zhen-Hua Ma Qing-Yong Ma Huan-Chen Sha Sheng-Li Wu Jun Wen 2009World Journal of Gastroenterology2009,15,20:3
2慢性胰腺炎临床特征分析显示文摘目的探讨慢性胰腺炎(CP)的病因、临床特点、诊断和治疗措施。方法回顾性总结2008年2月-2011年12月间住院的47例CP患者的临床诊治特点。结果47例CP患者中,胆源性24例(51.1%),酒精性17例(36.2%);腹部疼痛40例(87.2%),排便次数增多及脂肪泻12例(25.5%),糖尿病13例(27.6%)。临床症状结合超声检查基本确诊者16例(34.0%),CT检查确诊41例(87.2%),经内镜逆行性胰胆管造影检查确诊者31例(88.6%)。腹部X线平片发现有钙化灶者9例。以Ⅱ型和1期患者居多,分别为44.7%和51.1%,其次为Ⅳ型和3期。行手术治疗者13例(27.6%),腹痛症状明显缓解者10例;内镜下治疗者24例(51.6%),腹痛缓解者21例;单纯药物治疗者10例(21.2%),药物选择胰酶制剂、质子泵抑制剂,对合并糖尿病者予以口服降糖药治疗。疼痛明显的加用止痛剂,药物治疗后平均7~14d,疼痛减轻,完全缓解4例。结论CP发病原因以胆源性为主,CP的疼痛治疗困难,需内科、内镜和外科的综合治疗。付丹 2014华西医学2014,29,4:0
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