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    题名 作者 年代 出处 被引量
1Distinct memory traces for two visual features in the Drosophila brain显示文摘Gang Liu Holger Seiler Ai Wen Troy Zars Kei Ito Reinhard Wolf Martin Heisenberg Li Liu 2006中国生物学文摘2006,20,3:17
2Epidemiological Evolution of Lung Cancer in the South of Spain from 1990 to 2010显示文摘Background: Changes in lung cancer has been characterized by the increase of cases among women and the increase in adenocarcinomas among other histological subtypes.Methods: Descriptive analysis of cases diagnosed with lung cancer in Hospital Virgen de las Nieves(Spain) from 1990 to 2010,based on five variables(age, sex, smoking, histology and pathological anatomy). The study establishes associations between these variables and compares the results with the literature.Results: 2,026 patients were diagnosed with lung cancer in this period; 1,838 were males(90.7%) and 188 women(9.3%); 1,892 patients(93.4%) were smokers or ex-smokers and 134(6.6%) had never smoked; the most frequent non-small cell histology types were squamous cell carcinoma and adenocarcinoma and it was the most frequent neoplasia in women and were associated with a lower tobacco consumption.Conclusion: The large majority of lung cancer cases is associated with a history of smoking tobacco and there are histopathological differences according to gender and cumulative tobacco smoke load.Alberto Caballero Vázquez Ana Dolores Romero Ortiz Jose Manuel González de Vega San Román Raimundo García del Moral Bernardino Alcázar Navarrete 2018中国肺癌杂志2018,21,1:17
3典型甜菊糖苷的抗氧化和抗炎活性显示文摘本文以6种代表性甜菊糖苷及其肠道代谢物甜菊醇以及甜菊醇的重排异构体异甜菊醇为对象,研究了上述甜菊化合物的抗氧化性及其对鼠巨噬细胞Raw264.7的细胞毒性和抗炎活性。结果表明,所试甜菊糖苷在100μg/mL内对鼠巨噬细胞的Raw264.7均无细胞毒性,也不会诱导炎症反应;其中异甜菊醇抗炎效果最优,100μg/mL时相对于脂多糖刺激后产生的NO含量降低了约30.7%。所试甜菊糖苷对DPPH·和·OH两种自由基的清除率最高分别为24.8%和13.8%,其对DPPH·的清除能力具有结构相关性,但对·OH清除率均低,无结构相关性;而甜菊酚对DPPH·和ABTS^+·清除率分别为92.1%和29.6%,即甜菊提取物的自由基清除率主要由甜菊酚产生。张童童 隋晓辰 夏咏梅 Khaing zar myint 陈俊名 刘湘 2019食品工业科技2019,40,8:12
4Mitochondrial protection by low doses of insulin-like growth factor-Ⅰin experimental cirrhosis显示文摘AIM: To characterize the mitochondrial dysfunction in experimental cirrhosis and to study whether insulin-like growth factor-Ⅰ(IGF-Ⅰ) therapy (4 wk) is able to induce beneficial effects on damaged mitochondria leading to cellular protection. METHODS: Wistar rats were divided into three groups: Control group, untreated cirrhotic rats and cirrhotic rats treated with IGF-Ⅰtreatment (2 μg/100 g bw/d). Mitochondrial function was analyzed by flow cytometry in isolated hepatic mitochondria, caspase 3 activation was assessed by Western blot and apoptosis by TUNEL in the three experimental groups. RESULTS: Untreated cirrhotic rats showed a mitochon- drial dysfunction characterized by a significant reduction of mitochondrial membrane potential (in status 4 and 3); an increase of intramitochondrial reactive oxigen species (ROS) generation and a significant reduction of ATPase activity. IGF-Ⅰtherapy normalized mitochondrial func-tion by increasing the membrane potential and ATPase activity and reducing the intramitochondrial free radical production. Activity of the electron transport complexes Ⅰand Ⅲ was increased in both cirrhotic groups. In addition, untreated cirrhotic rats showed an increase of caspase 3 activation and apoptosis. IGF-Ⅰtherapy reduced the expression of the active peptide of caspase 3 and resulted in reduced apoptosis.Raquel Pérez María García-Fernández Matías Díaz-Sánchez Juan E Puche Gloria Delgado Marian Conchillo Jordi Muntané Inma Castilla-Cortázar 2008World Journal of Gastroenterology2008,14,17:11
5Probiotics as Control Agents in Aquaculture显示文摘Infectious diseases constitute a limiting factor in the development of the aquaculture production, and control has solely concentrated on the use of antibiotics. However, the massive use of antibiotics for the control of diseases has been questioned by acquisition of antibiotic resistance and the need of alternative is of prime importance. Probiotics, live microorganisms administered in adequate amounts that confer a healthy effect on the host, are emerging as significant microbial food supplements in the field of prophylaxis.Gómez R. Geovanny D Balcázar José Luis 2007Journal of Ocean University of China2007,6,1:10
6植物源抑菌剂的抗氧化性及其在食品中的应用显示文摘植物提取物由于其抗氧化和抑菌特性引起了研究人员的广泛兴趣。植物源抑菌剂在肉类和其他食品工业中可作为功能性成分,防止微生物生长,延长食品保质期。植物抑菌剂还可以提高包装膜的有效性、改善包装性能,减少环境浪费。本综述对植物提取物的抑菌和抗氧化的特性进行了评价,同时讨论了植物提取物在食品工业中的应用。庆九 Khaing zar Myint 俞新南 于倩男 2021中国食品添加剂2021,32,3:5
7Removing contaminants from tannery wastewater by chemical precipitation using CaO and Ca(OH)2显示文摘The removal of Cr,sulfates and Chemical Oxygen Demand(COD)from industrial tannery wastewater by chemical precipitation was carried out using Calcium oxide(CaO)and Calcium hydroxide(Ca(OH)2).Different doses of alkalis,ranging from deficiency to excess hydroxyl species over the stoichiometric necessary,were used to remove theoretically the 100%of Cr[0.3-3.2 g alkali·(g Cr^3+)^-1].The precipitation was carried out at room temperature,10 min of vigorous stirring,200 r·min^-1 and a settling time of 24 h,followed by separation and characterization of liquid product.As result of addition of alkalis,pH underwent increase as did the alkali concentration.The removal of Cr,and sulfates also increased as alkali concentration did,although for first species the changes at higher alkali contents were less evident.COD removal on the other hand,did not follow a unique trend,instead exhibited a maximum.Based on our results,selection of a specific dose of alkali was carried out taking as reference the efficiency on total chromium removal,keeping the pH in the range 7 to 9 to ensure Cr precipitation as chromium hydroxide.With those conditions,jar test was used to produce enough liquid product in order to determine the removal percent of several other species.The removal percent of the species was as follows:Cr,SO4^2-,ZnSO4,FeSO4,CN^-1,NiSO4,Fe2[Fe(CN)6]at 99.8%,66.9%,99.6%,21.4%,70.9%,52.8%and 76.4%with CaO,and 99.8%,61.6%,99.9%,7.1%,84.0%,54.4%and 90.5%with Ca(OH)2,respectively.Adriana Reyes-Serrano Joel ELópez-Alejo Manuel AHernández-Cortázar Ignacio Elizalde 2020Chinese Journal of Chemical Engineering2020,28,4:4
8伺服阀前置级流场气穴现象的仿真及试验研究显示文摘针对液压阀中的气穴现象会引起液压阀的噪音、性能恶化,甚至导致液压阀失效等问题,对伺服阀前置级喷嘴和挡板之间流场中的气穴现象进行了研究。利用Pro/E软件对流场进行了三维建模,用前处理软件Gambit对三维模型进行了网格划分及边界条件设置,利用标准k-ε模型和混合气穴模型建立流场的数学模型,运用FLUENT软件对不同喷嘴入口流速下流场的分布特性及气穴特征进行了仿真分析;同时利用高速摄像机对喷嘴挡板之间的流场分布进行了观测和记录。研究结果表明,在低雷诺数流动条件下,气穴开始在喷嘴外壁和挡板前端的边缘形成;随着雷诺数的增大,在挡板弯曲的附体气穴逐渐长大并随着射流流速的增加出现云状的气穴。将不同流动条件下流场结构和气穴分布的数值计算结果与试验观测结果进行比较,两者基本吻合,说明伺服阀前置级流场气穴仿真模型和数值计算方法是可靠的。韩笑 Nay Zar Aung 曹俊章 李松晶 2014机电工程2014,31,10:4
9Systematic study of the dependence of magnetic and structural properties of Nd2Fe14B powders on the average particle size显示文摘A systematic study of the magnetic and structural properties dependence on the particle size was realized.For this,commercial NdFeB powder was separated into five different mean particle sizes using sieves.Besides,from the original powder,eleven samples were also produced by mechanical milling assisted by surfactant,using various milling times.A total of sixteen samples were studied by scanning electron microscopy(SEM),X-ray diffraction(XRD),vibrating sample magnetometry(VSM),and Mdssbauer spectrometry(MS).The particle sizes of the samples vary from the micrometer to the nanometer scale.The crystallite size decreases with decreasing particle size.XRD result indicates that the Nd2Fe14B phase is found in all the samples,and the presence of this phase is also corroborated by MS using six sextets for fitting their spectra,with an additional singlet corresponding to the Nd1.1Fe4B4 phase.The mean hyperfine magnetic field increases with increasing particle size because the magnetic dipolar interaction between the magnetic moment of the particles increases with particle size.From the VSM measurements the magnetic energy density(BH)max values were calculated for different particle sizes,and their maximum value of 34.45 MGOe is obtained for the sample with the particle size of 60μm.J.F.Durán Perdomo G.A.Pérez Alcázar H.D.Colorado J.A.Tabares L.E.Zamora J.J.S.Garitaonandia 2020Journal of Rare Earths2020,38,9:3
10Food-specific IgG4 antibody-guided exclusion diet improves symptoms and rectal compliance in irritable bowel syndrome显示文摘Sameer Zar Lynne Mincher Martin J. Benson Devinder Kumar 2005Scandinavian Journal of Gastroenterology2005,,7:2
11Relation of atrophic gastritis with Helicobacter pylori-CagA^+ and interleukin-1 gene polymorphisms显示文摘AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory poly-morphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer. METHODS: Seven biopsy specimens, a fasting blood sample and a questionnaire concerning nutritional and sociodemographic factors were obtained from 501 con-secutive patients who had undergone endoscopy for dyspeptic symptoms. A histopathological diagnosis was made. Pepsinogen concentrations were analyzed by enzyme linked immunosorbent assay (ELISA). Infection with H pylori CagA+ was determined by serology and polymerase chain reaction (PCR). IL-1B and IL-1RN polymorphisms genotyping was performed by PCR-restriction fragment length polymorphism (PCR-RFLP)and PCR respectively. RESULTS: In this dyspeptic population, 86% were H pylori positive and of these, 67.8% were positive for CagA. Atrophic antral gastritis (AAG) was associated with CagA+ status [odd ratio (OR) = 4.1; P < 0.000] and fruit consumption (OR = 0.3; P < 0.00). Atrophic body gastritis (ABG) was associated with pepsinogen PGI/PGII < 3.4 (OR = 4.9; P < 0.04) and alcohol consumption (OR = 7.3; P < 0.02). Duodenal ulcer was associated with CagA+ (OR = 2.9; P < 0.04) and smoking (OR = 2.4; P < 0.04). PGI < 60 μg/L as well as PGI/PGII < 3.4 were associated with CagA+. CONCLUSION: In a dyspeptic population in Costa Rica, H pylori CagA+ is not associated with ABG, but it is a risk factor for AAG. The pro-inflammatory cytokine poly-morphisms IL-1B + 3945 and IL-1RN are not associated with the atrophic lesions of this dyspeptic population.Rafaela Sierra Clas Une Vanessa Ramírez Warner Alpízar-Alpízar María I González José A Ramírez Antoine de Mascarel Patricia Cuenca Guillermo Pérez-Pérez Francis Mégraud 2008World Journal of Gastroenterology2008,14,42:2
12食物特异性IgG4抗体指导的限制性饮食可改善肠易激综合征症状和直肠顺应性Zar S. Mincher L. Benson M.J. Kumar D. 郝筱倩 2005世界核心医学期刊文摘(胃肠病学分册)2005,0,12:2
13Pulmonary Vein Denervation Enhances Long-Term Benefit After Circumferential Ablation for Paroxysmal Atrial Fibrillation显示文摘Carlo Pappone Vincenzo Santinelli Francesco Manguso Gabriele Vicedomini Filippo Gugliotta Giuseppe Augello Patrizio Mazzone Valter Tortoriello Giovanni Landoni Alberto Zangrillo Christopher Lang Takeshi Tomita Cézar Mesas Elio Mastella Ottavio Alfieri 2004Circulation: Journal of the American Heart Association2004,,3:2
14The role of probiotics in aquaculture显示文摘José Luis Balcázar Ignacio de Blas Imanol Ruiz-Zarzuela David Cunningham Daniel Vendrell José Luis Múzquiz 2006Veterinary Microbiology2006,,3:2
15Expression of Epstein-Barr Virus-encoded Latent Membrane Protein (LMP-1), p16 and p53 Proteins in Nonendemic Nasopharyngeal Carcinoma (NPC): A Clinicopathological Study显示文摘Samuel Rosales-Pérez Ana M. Cano-Valdez Christian H. Flores-Balcázar Ferran Guedea-Edo Leonardo S. Lino-Silva Alicia Lozano-Borbalas Arturo Navarro-Martín Adela Poitevin-Chacón 2014Archives of Medical Research2014,,:2
16Role of food hypersensitivity in irritable bowel syndrome显示文摘Zar S Kumar D 2002Minerva Med2002,93,5:1
17Uniqueness and boundary behaviour of large solutions to elliptic problems with singular weights显示文摘Chuaqui M Cortázar C Elgueta M 2004CPAA2004,3,4:1
18Estimating Demand for a Cycleway Network显示文摘ORTúZAR J D D IACOBELLI A VALEZE C 2000Transportation Research Part A:Policy and Practice2000,34,5:1
19Histologic proof of acalculous cholecystitis due to Cyclospora cayetanensis 显示文摘Zar FA el-Bayoumi E Yungbluth MM 2001Clin Infect Dis2001,33,12:1
20Cyclooxygenase (COX) inhibitors induce apoptosis in nonsmall cell lung cancer through cyclooxygenase in-dependent pathways显示文摘 Bradbury DA Pang L 2003Lung Cancer2003,40,:1
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