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| 1 | Single vs dual(en bloc) kidney transplants from donors ≤ 5 years of age: A single center experience显示文摘AIM: To compare outcomes between single and dual en bloc(EB) kidney transplants(KT) from small pediatric donors. METHODS: Monocentric nonprospective review of KTs from pediatric donors ≤ 5 years of age. Dual EB KT was defined as keeping both donor kidneys attached tothe inferior vena cava and aorta, which were then used as venous and arterial conduits for the subsequent transplant into a single recipient. Donor age was less useful than either donor weight or kidney size in decision-making for kidney utilization as kidneys from donors < 8 kg or kidneys < 6 cm in length were not transplanted. Post-transplant management strategies were standardized in all patients.RESULTS: From 2002-2015, 59 KTs were performed including 34 dual EB and 25 single KTs. Mean age of donors(17 mo vs 38 mo, P < 0.001), mean weight(11.0 kg vs 17.4 kg, P = 0.046) and male donors(50% vs 84%, P = 0.01) were lower in the dual EB compared to the single KT group, respectively. Mean cold ischemia time(21 h), kidney donor profile index(KDPI; 73% vs 62%) and levels of serum creatinine(SCr, 0.37 mg/d L vs 0.49 mg/d L, all P = NS) were comparable in the dual EB and single KT groups, respectively. Actuarial graft and patient survival rates at 5-years follow-up were comparable. There was one case of thrombosis resulting in graft loss in each group. Delayed graft function incidence(12% dual EB vs 20% single KT, P = NS) was slightly lower in dual EB KT recipients. Initial duration of hospital stay(mean 5.4 d vs 5.6 d) and the one-year incidences of acute rejection(6% vs 16%), operative complications(3% vs 4%), and major infection were comparable in the dual EB and single KT groups, respectively(all P = NS). Mean 12 mo SCr and abbreviated MDRD levels were 1.17 mg/d L vs 1.35 mg/d L and 72.5 m L/min per 1.73 m^2 vs 60.5 m L/min per 1.73 m^2(both P = NS) in the dual EB and single KT groups, respectively. CONCLUSION: By transplanting kidneys from young pediatric donors into adult recipients, one can effectively expand the limited donor pool and achieve excellent medium-term outcomes. | Yousef Al-Shraideh Umar Farooq Hany El-Hennawy Alan C Farney Amudha Palanisamy Jeffrey Rogers Giuseppe Orlando Muhammad Khan Amber Reeves-Daniel William Doares Scott Kaczmorski Michael D Gautreaux Samy S Iskandar Gloria Hairston Elizabeth Brim Margaret Mangus Robert J Stratta | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 2 | Isolation and characterization of seven tetranucleotide microsatellite loci in mungbean, Vigna ra- diate显示文摘 | umar S V Tan G Quah S C | 2002 | Mol Ecol Notes2002，2，： | 1 |
| 3 | What do medical students expect in a teacher?显示文摘 | Kiani Q Umar S Iqbal M | 2014 | Clin Teach2014，11，3： | 1 |
| 4 | Association of commonpolymorphisms in TNFA,NFkBl and NFKBIA with risk and prog-nosis of esophageal squamous cell carcinoma显示文摘 | Umar M Upadhyay R Kumar S | 2013 | Plos One2013，8，81： | 1 |
| 5 | Pediatric pulmonary hypertension:Roles of endothelin-1 and nitric oxide显示文摘 | Black S M K umar S Wiseman D | 2007 | Clin Hemorheol Microcireulation2007，37，： | 1 |
| 6 | Biosorption of lead from aqueous so-lution by Ficus religiosa leaves:batch and column study显示文摘 | QAISER S SALEEMI A R UMAR M | 2009 | Journal ofHazardous Materials2009，166，23： | 1 |
| 7 | Electroanalytical determination of acetaminophen using nano-TiOz/polymer coated electrode in the presence of dopamine显示文摘 | umar S A K Tang C F Chela S M | 2008 | Talanta2008，76，： | 1 |
| 8 | Synthesis and characterization of polyaniline-Fe3O4 nanocmoposite:Electrical conductivity,magnetic,electrochemical studies显示文摘 | Umare S S Shambharkar B H Ningthoujam R S | 2010 | Synthetic Metals2010，160，： | 1 |
| 9 | Hydrogeological and hydrochemical framework of regional aquifer system in Kali-Ganga Sub-basin,India显示文摘 | Umar A Umar R Ahmad M S | 2001 | Environmental Geology2001，40，45： | 1 |
| 10 | Antiapoptotic effects of: pro- gastrin on pancreatic cancer cells aremediated by sustained activation of nuclear factor- { kappa } B 显示文摘 | Rengifo-Cam W Umar S Sarkar S | 2007 | Cancer Res2007，67，15： | 1 |
| 11 | Nitric oxide and nitric oxide synthase isoforms in the normal,hypertrophic,and failing heart显示文摘 | Umar S van der Laarse A | 2010 | Mol Cell Biochem2010，333，12： | 1 |
| 12 | Increased beta-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo显示文摘 | Sellin JH Umar S Xiao J | 2001 | Cancer Res2001，61，7： | 1 |
| 13 | Fatty-acid oxidation and calci- um homeostasis are involved in the rescue of bupivacaine-induced cardiotoxicity by lipid emulsion in rats 显示文摘 | Partownavid P Umar S Li J | 2012 | Crit Care Med2012，40，8： | 1 |
| 14 | The microbial community composition changes rapidly in the early stages of decomposition of wheat residue显示文摘 | Marschner P Umar S Baumann K | | 0，，： | 1 |
| 15 | Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension显示文摘 | UMAR S DE VISSER YP STEENDIJK P | 2009 | Am J Physiol Heart Circ Physiol2009，297，5： | 1 |
| 16 | Esophageal cancer:epidemiology,pathogenesis and prevention显示文摘 | UMAR S B FLEISCHER D E | 2008 | Nat Clin Pract Gastroenterol Hepatol2008，5，9： | 1 |
| 17 | Fatty-acid oxidation and calci- um homeostasis are involved in the rescue of bupivacaine-induced cardiotoxicity by lipid emulsion in rats 显示文摘 | Partownavid P Umar S Li J | 2012 | Crit Care Med2012，40，8： | 1 |
| 18 | Effect of SOP on yield and quality of potato显示文摘 | Bansal S K and Umar S | 1998 | Fertiliser News1998，43，11： | 1 |
| 19 | Scorpion venom(Odontobuthus doriae) induces apoptosis by depolarization of mitochondria and reduces S-phase population in human breast cancer cells(MCF-7)显示文摘 | Zargan J Umar S Sajad M | | 0，，08： | 1 |
| 20 | Catalytic Ring-opening Polymerization of L-lactide by Titanium Biphenoxy-alkoxide Initiators显示文摘 | Umare P S Tembe G L Rao K V etal | 2007 | Journal of Molecular Catalysis A:Chemical2007，268，： | 1 |
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