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| 1 | Hepatitis E virus infection: Epidemiology and treatment implications显示文摘Hepatitis E virus(HEV) infection is now established as an emerging enteric viral hepatitis. Standard treatments in acute and chronic hepatitis E remain to be established. This study undertakes a review of the epidemiology, treatment implication and vaccine prevention from published literature. HEV infection is a worldwide public health problem and can cause acute and chronic hepatitis E. HEV genotypes 1 and 2 are primarily found in developing countries due to waterborne transmission, while the zoonotic potential of genotypes 3 and 4 affects mostly industrialized countries. An awareness of HEV transmission through blood donation, especially in the immunocompromised and solid organ transplant patients, merits an effective anti-viral therapy. There are currently no clear indications for the treatment of acute hepatitis E. Despite concerns for side effects, ribavirin monotherapy or in combination with pegylatedinterferon alpha for at least 3 mo appeared to show significant efficacy in the treatment of chronic hepatitis E. However, there are no available treatment options for specific patient population groups, such as women who are pregnant. Vaccination and screening of HEV in blood donors are currently a global priority in managing infection. New strategies for the treatment and control of hepatitis E are required for both acute and chronic infections, such as prophylactic use of medications, controlling large outbreaks, and finding acceptable antiviral therapy for pregnant women and other patient groups for whom the current options of treatment are not viable. | Ga Young Lee Kittiyod Poovorawan Duangnapa Intharasongkroh Pattaratida Sa-nguanmoo Sompong Vongpunsawad Chintana Chirathaworn Yong Poovorawan | 2015 | World Journal of Virology2015，4，4： | 5 |
| 2 | Autologous serum in the management of recalcitrant dry eye syndrome显示文摘 | Lee GA Chen SX | 2008 | Clin Experiment Ophthalmol2008，36，2： | 1 |
| 3 | Non-coding RNAs and cancer: newparadigms in oneology 显示文摘 | Lee SK Calin GA | 2011 | Diseov Med2011，11，58： | 1 |
| 4 | The Mode Selection Trial(MOST)in sinus node dysfunction design,rationale,and baseline characteristics of the first 1000 patients显示文摘 | Lamas GA Lee KL Sweeney MO | 2000 | Am Heart J2000，140，4： | 1 |
| 5 | Ventricular pacing or dual-chamber pacing for sinus-node dysfunction显示文摘 | Lamas GA Lee KL Sweeny MO | 2002 | N Engl J Med2002，346，24： | 1 |
| 6 | Role of tetrabenazine for Hunting- ton~ disease - associated chorea 显示文摘 | Poon LH Kang GA Lee AJ | 2010 | Ann Pharmacother2010，44，6： | 1 |
| 7 | Ventrieulur pacing or dualchamber pacing for sinus-node dysfunction显示文摘 | Lee KL Sweeney MO | 2002 | N End J Med2002，346，： | 1 |
| 8 | Revision strategies for salvaging or improving failed cylindrical cages显示文摘 | McAfee PC Cunningham BW Lee GA | 1999 | Spine1999，24，20： | 1 |
| 9 | Focal lesions in the cirrhotic liv- er:high resolutions Ex Vivo MRI with pathologic correlation显示文摘 | Krinsky GA Lee VS Theise ND | 2000 | J Comput Assist Tomogr2000，24，2： | 1 |
| 10 | Selective photostimulation of genetically charged neurons 显示文摘 | Zemelman BV Lee GA Ng M | 2002 | Neuron2002，33，1： | 1 |
| 11 | SmartPlug in the management of severe dry eye syndrome显示文摘 | Chen SX Lee GA | | 0，，05： | 1 |
| 12 | Selective photostimulation of genetically chARGed neurons显示文摘 | Zemelman BV Lee GA Ng M | 2002 | Neuron2002，33，1： | 1 |
| 13 | Gadolinium-enhanced MR angiography:artifacts and pitfalls显示文摘 | Lee VS Martin DJ Krinsky GA | 2000 | AJR2000，175，： | 1 |
| 14 | Revision strategies for salvaging or improving failed cylindrical cages显示文摘 | Mcafee PC Cunningham BW Lee GA | | 0，，1976： | 1 |
| 15 | H epatocelluar carcinoma and dysplastic nodules in patients with cirrhosis: prospective di agnosis with MR imaging and explantation correlation显示文摘 | K rinsky GA Lee VS Theise ND | 2001 | Radi ology2001，219，2： | 1 |
| 16 | Adverse outcomes and opioid analgesic administration in acute abdominal pain 显示文摘 | Lee JS Stiell IG Wells GA | 2000 | Acad Emerg Med2000，7，9： | 1 |
| 17 | Revision strategies for salvaging or improving failed cylindrical cages显示文摘 | McAfee PC Cunningham BW Lee GA | 1999 | Spine1999，24，20： | 1 |
| 18 | MR imaging of cirrhotic nodules显示文摘 | Krinsky GA Lee VS | 2000 | Ab- dom Imaging2000，25，47： | 1 |
| 19 | Ventricular pacing or dual-chamber pacing for sinus-node dysfunction 显示文摘 | Lamas GA Lee KL Sweeney MO | 2002 | N Engl J Med2002，346，： | 1 |
| 20 | Long non-coding RNA HOTAIR is associated with human cervical cancerprogression显示文摘 | Hee Kim Dae Lee Ga Yim Eun Nam Sunghoon Kim Sang Kim Young Kim | 2015 | International Journal of Oncology2015，，： | 1 |
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