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| 1 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 2 | Processing stoichiometric silicon carbide fibers from polymethylsilane, part I precursor fiber processing显示文摘 | ZHANG Z F SCOTTO C S LAINE R M | 1998 | J Mater Chem1998，8，： | 2 |
| 3 | Long-term effects of water level drawdown on the vegetation of drained pine mires in Southern Finland显示文摘 | Laine J Vasander H Laiho R | 1995 | Journal of Applied Ecology1995，32，4： | 1 |
| 4 | Systematic review: the lower gas- trointestinal adverse effects of non-steroidal anti-inflammatory drugs 显示文摘 | Laine L Smith R Min K | 2006 | Aliment Pharmacol Ther2006，24，5： | 1 |
| 5 | Bile duct injuries during laparoscopic cholecystectomy:primary and long-term results from a single institution显示文摘 | Karvonen J Gullichsen R Laine S | 2007 | Surg Endosc2007，21，7： | 1 |
| 6 | Genome sequence and analysis of the soil cellulolytic actinomyeete Thermobifidafusca YX 显示文摘 | Athanasios L Konstantinos M Natalia I lain A Miriam L Genevieve D Michele M Alia L Susan L Alex C Paul R David BW Nikos K | 2007 | J Bacteriol2007，189，6： | 1 |
| 7 | Bile duct injuries during laparoscopic cholecystectomy:primary and long-term results from a single institution显示文摘 | Karvonen J Gullichsen R Laine S | | 0，，07： | 1 |
| 8 | Sindbis viruses and other alphaviruses as cause of human arthritic disease显示文摘 | Laine M Luukkainen R Toivanen A | 2004 | J Intern Med2004，256，6： | 1 |
| 9 | A stochastic finite element method for fatigue reliability analysis of gear teeth subjected to bending显示文摘 | Peng X Q Liu Geng Wu Liyan Liu G R Lain K Y | 1998 | Computational Mechanics1998，21，： | 1 |
| 10 | Polyhedral phenylsilsesquioxanes显示文摘 | LAINE R M ROLL M F | | 0，，03： | 1 |
| 11 | Development of ultra-battery for hybrid-electric vehicle applications显示文摘 | Lain L T Louey R | 2006 | Journal of Power Sources2006，158，2： | 1 |
| 12 | Antimicrobialcatheters for reduction of symptomatic urinary tract infection in adults requiring short-term catheterisation in hospital: a multicentre randomised controlled trial显示文摘 | Pickard R Lain T MacLennan G | 2012 | Lancet2012，380，9857： | 1 |
| 13 | Systematic review:the lower gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs显示文摘 | Laine L Smith R Min K | 2006 | Aliment Pharmacol Ther2006，24，5： | 1 |
| 14 | Group Ⅱ tris(glycolato)silicates as precursors to silicate glasses and ceramics显示文摘 | KANSAL P LAINE R M | 1995 | J Am Ceram Soc1995，78，3： | 1 |
| 15 | Bile duct in- juries during laparoscopic cholecystectomy: primary and long-term results from a single institution 显示文摘 | KARVONEN J GULLICHSEN R LAINE S | 2007 | Surg Endosc2007，21，7： | 1 |
| 16 | Systematic review and meta- analysis of adverse events of low-dose aspirin and clo -pidogrel in randomized controlled trials 显示文摘 | McQuaid K R Laine L | 2006 | Am J Med2006，119，： | 1 |
| 17 | Systematic review:the lower gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs显示文摘 | Laine L Smith R Min K | 2006 | Aliment Pharmacol Ther2006，24，： | 1 |
| 18 | Scalable Threshold Closure 显示文摘 | Zhang C R Lain K Y Jajodia S | 1999 | Theoretical Computer Science1999，226，12： | 1 |
| 19 | Theoretical Process Development for Freeze-Drying Spray-Frozen Aerosols显示文摘 | McGrath P J Laine R M | 1992 | Journal of American Ceram Socity1992，，8： | 1 |
| 20 | A Polyimide Nanocomposite from Oeta(aminophenyl)silsesquioxane显示文摘 | Tamaki R Choi J Laine R M | 2003 | Chemistry of Material2003，15，： | 1 |
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