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| 1 | 腰椎皮质骨椎弓根螺钉与传统椎弓根钉置钉点骨密度差异之比较显示文摘椎弓根螺钉目前广泛应用于治疗各种腰椎疾患,尽管其在重建腰椎稳定性方面优势非常明显,但螺钉松动、移位、拔出等并发症时有发生,不仅影响手术疗效,甚至还需要二次手术翻修。Santoni等于2009年提出皮质骨钉道(corticalbonetrajector,CBT)椎弓根螺钉(简称CBT螺钉)固定技术,其轴向拔出力较传统椎弓根螺钉平均提升30%,具有显露更少、切口更短、术后康复更快等优点。众所周知,骨密度(bonemineraldensity,BMD)与螺钉拔出力呈正相关。传统椎弓根螺钉末端常位于椎体中段松质骨内,随年龄增长,松质骨BMD下降,螺钉固定的风险增加并可最终导致螺钉松动。而CBT螺钉固定点位于椎弓根及椎体皮质骨中,理论上降低了螺钉松动的风险,即使是老年患者,其置钉位置的BMD也较传统椎弓根螺钉置入的椎体中部更能有效维持;而当获得与传统椎弓根螺钉相同或更好的机械稳定性时,CBT螺钉所需的长度也更短,这一点在骨量减少或骨质疏松患者的尸体研究中得到进一步证实。 | Mai HT Mitchell SM Hashmi SZ 胡玮 马向阳 | 2016 | 中国骨科临床与基础研究杂志2016，8，5： | 21 |
| 2 | Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2+ transients and contraction in cardiomyocytes derived from embryonic stem cells显示文摘 | Fu JD Li J Tweedie D Yu HM Chen L Wang R Riordon DR Brugh SA Wang SQ Boheler KR Yang HT | 2006 | 中国生物学文摘2006，20，7： | 9 |
| 3 | Emerging role of junctophilin-2 as a regulator of calcium handling in the heart显示文摘Junctophilin-2 (JPH2 ) 是在心脏的 myocytes 在 junctional 膜建筑群(JMC ) 的组织起一个关键作用的膜绑定蛋白质。JPH2 被相信在 JMC 以内在固定距离保留血浆膜和 sarcoplasmic 蜂窝胃,它在刺激收缩过程期间为合适的导致 Ca2+ 的 Ca2+ 版本是必要的。最近的研究表明了在 JPH2 基因的变化与 hypertrophic 心肌症被联系,强调为正常心脏的生理学的这蛋白质的重要性。在这份报纸,我们在心关于 junctophilin-2 的结构和功能考察当前的知识。 | Alejandro GARBINO | 2010 | Acta Pharmacologica Sinica2010，31，9： | 7 |
| 4 | Transfusion transmitted virus infection in general populations and patients with various liver diseases in south China显示文摘INTRODUCTIONAlthough several specific detecting methods hadbeen applied to determine the hepatitis virus,therewas a lot of cryptogenic hepatitis without anyknown hepatitis infectious marker.Theprevalence of hepatitis G virus (HGV) (also knownas GB-C virus) infection has been reported to be 5%-13% in patients with non-A-E hepatitis andcirrhosis,however,there is little evidencesuggesting that HGV causes hepatitis in human. | Chen YP Liang WF Zhang L He HT Luo KX | 2000 | World Journal of Gastroenterology2000，6，5： | 7 |
| 5 | Endoscopic full-thickness resection of gastric stromal tumor arising from the muscularis propria显示文摘 | Zhang B Huang LY Wu CR Cui J Jiang LX Zheng HT | 2013 | Chinese Medical Journal2013，，13： | 7 |
| 6 | 血液透析患者冠状动脉药物洗脱支架植入术后的双联抗血小板治疗和临床结局显示文摘近日,临床肾脏领域权威杂志Clin J Am Soc Nephrol上发表了一篇研究文章,研究人员试图明确血液透析患者冠状动脉药物洗脱支架(drug—eluting stent,DES)植入后进行双联抗血小板治疗(dual antiplatelet therapy,DAPT)的益处和风险。血液透析患者接受DES和DAPT治疗后进行巢式病例对照分析。DES植入后1年内心肌梗死或死亡的病例与对照患者一一配对。主要结局是死亡和心肌梗塞;次要结局是缺血性卒中、血运重建和大出血。 | 王建中 Chen YT Chen HT Hsu CY | 2017 | 中华肾病研究电子杂志2017，6，2： | 5 |
| 7 | A chemical index of weather-ing without effect of wind sorting: Fe/Mg ratios in the acid-insoluble phases of loess deposits显示文摘Chemical analysis of acid-insoluble fractions in loess and paleosols shows that concentrations of Fe and Mg were under control of wind sorting and post-depositional weathering-pedogenesis. The former caused Fe and Mg concentrated in the finer grain-size fractions, displaying synchronous variations, while the latter made Fe and Mg separated, leading to Fe retained in the weathered section and Mg leached out. Therefore, Fe/Mg ratios in the acid insoluble fraction of loess and paleosols can eliminate the effect of wind sorting and serve as an excellent proxy record on intensity of weathering-pedogenesis. Based on calculation, leaching percentage of Mg in the paleosol S1 from the Luochuan, Xifeng and Huanxian sections is 15%, 11% and 2%, respectively, and on average 9% for the paleosols S2—S14 from the Luochuan section, with the highest value amounting to 22% in S5-1, suggesting the strongest weathering-pedogenesis. | Liu, LW Chen, J Wang, HT Chen, Y | 2001 | Chinese Science Bulletin2001，46，16： | 5 |
| 8 | Value of a new stick-type rapid urine test for the diagnosis of Helicobacter pylori infection in the Vietnamese population显示文摘AIM:To assess the value of a new test for the diagnosis of Helicobacter pylori(H.pylori) infection,Rapirun H.pylori Antibody Stick(Rapirun Stick),in a Vietnamese population.METHODS:Eligible patients without previous history of H.pylori eradication were recruited.Rapid urease test(RUT) and histologic examination were used to diagnose the H.pylori infection.Patients were considered H.pylori positive when the RUT results were positive and/or the bacteria were detected histologically.Rapirun Stick tests were performed using urine samples,and the results were compared with the other 2 methods.RESULTS:We enrolled 200 patients with a mean age of 36(range,18-76) years.There were 116 females and 84 males.Of the 200 patients,111(55.5%) were diagnosed as being H.pylori positive.The sensitivity,specificity,and accuracy of the Stick test were 84.7%,89.9%,and 87.0%,respectively.There were 17(8.5%) falsenegative patients and 9(4.5%) false-positive patients.CONCLUSION:The Rapirun Stick test has high sensitivity,specificity,and accuracy for the diagnosis of H.pylori infection in the Vietnamese population.The test can be clinically applied in Vietnamese populations. | Duc T Quach Toru Hiyama Fumio Shimamoto Quang D Le Linh X Ho Nhu HT Vu Masaharu Yoshihara Naomi Uemura | 2014 | World Journal of Gastroenterology2014，20，17： | 4 |
| 9 | Molecular cloning of differentially expressed novel rice genes induced by Magnaporthe grisea显示文摘WE have applied the differential display (D. D.) of mRNA method to detect and clone tran-scripts that were differentially expressed between rice NILs (Near-isogenic lines) H7R (resis-tant) and H7S (susceptible) which were induced by Magnaporthe grisea. The cDNA gene-tags obtained from D. D. analysis were reamplified by PCR and screened by Southern | He, ZH Dong, HT Cheng, SJ Wu, YL Dong, JX Li, DB | 1997 | Chinese Science Bulletin1997，42，20： | 4 |
| 10 | 声音通过皮质丘脑环路缓解疼痛显示文摘声音(包括音乐和噪音)可以减轻人类的疼痛,但潜在的神经机制仍然未知。该研究发现高于环境噪音5-dB的声音可以缓解疼痛。病毒追踪、显微内镜钙成像和在体多通道记录表明,低信噪比(SNR)声音抑制了从听觉皮质(ACx)到丘脑后核(PO)和丘脑腹后核(VP)的谷氨酸能输入。光遗传学或化学遗传学抑制ACx^(Glu)→PO和ACx^(Glu)→VP环路分别模拟了低SNR声音对炎症痛模型小鼠后爪和前爪的镇痛作用,而激活这些环路可反转声音诱导的镇痛作用。该研究通过解读听觉系统在疼痛处理中的作用,揭示声音促进镇痛作用背后的皮质丘脑环路机制。 | Zhou WJ Ye CH Wang HT 胡丹丹(译) 张玲(校) | 2022 | 中国疼痛医学杂志2022，28，12： | 4 |
| 11 | Static Adsorption of Xenon on ACF at 257 K显示文摘The static adsorption of xenon on active carbon fiber (ACF) at 257 K was measured with ASAP2010 specific surface area and pore diameter distribution instrument by changing the working gas from nitrogen to xenon. Compared with grain activated carbon (GAC), the results were as follows: (1) The adsorption performance of Viscose-based ACF (VACF-As) was the best among all absorbents tested. VACF-A3 was the superior xenon absorbent. The performance of pitch-based ACF (PACF-Cs) approached that of GAC, (2) Due to the difference of aperture distribution, the adsorption performances of ACF with different radics were different under the same experiment conditions even though the specific surface area was similar, (3) There were some differences of adsorptive capacity among ACF absorbents which had the same radic, however there was not definite relationship between their specific surface area and adsorptive capacity, (4) The adsorption of xenon on all kinds of ACF agrees with Langmuir equation, (5) The adsorptive curves can be fitted with a binomial equation. | Zhang, HT Wang, YL Wang, XH Zhang, LX Chen, LY | 2002 | Journal of Materials Science & Technology2002，18，6： | 3 |
| 12 | Diagnosis and management of cystic duct leakage after laparoscopic cholecystectomy, report of 3 cases显示文摘 | Li JH Liu HT | 2005 | 第二军医大学学报2005，26，10： | 3 |
| 13 | 进行期胃癌患者癌周淋巴结淋巴细胞酶活性研究显示文摘本文作者应用电镜酶细胞化学方法,对7例进行期团生型与弥生型胃癌患者癌周淋巴结淋巴细胞酶活性进行了研究。结果表明:1.ATP酶主要定位于细胞膜胞质面,核膜及染色质等部位也有此酶反应颗粒。G—6—P酶主要定位在内质网。ATP酶与G—6—P酶活性在胃癌组明显减弱,弥生型更为显著。2.5'-ND酶定位在内质网、线粒体、核膜等部位。其活性在胃癌组明显增高。结果提示,ATP酶与G-6-P酶活性下降可能是进行期胃癌患者细胞免疫机能降低的主要原因之一。 | 蔡玉文 P.,HT | 1994 | 实用癌症杂志1994，9，1： | 2 |
| 14 | lnterventional endoscopic therapy of chronic pancreatitis 显示文摘 | Lohr M Schneider HT Farnbacher M | 1997 | J Gastroenterol1997，35，： | 2 |
| 15 | Motor evoked potentials in predicting recovery from upper extremity paralysis after acute strooke显示文摘 | Hendricks HT Pasman JW van Limbeek J | 2003 | Cerebrovasc Dis2003，16，3： | 2 |
| 16 | Difference between expression of adhesion molecules on CD34+ cells from bone marrow and G-CSF-stimulated peripheral blood 显示文摘 | Kroger N Zeller W Hassan HT | 1998 | Stem Cells1998，16，： | 2 |
| 17 | Constitutive renal Rel/nuclear factor-κB expression in Lewis polycystic kidney disease rats显示文摘AIM:To determine the temporal expression and pattern of Rel/nuclear factor(NF)-κB proteins in renal tissue in polycystic kidney disease(PKD). METHODS: The renal expression of Rel/NF-κB proteins was determined by immunohistochemistry, immunofluorescence and immunoblot analysis in Lewis polycystic kidney rats(LPK, a genetic ortholog of human nephronopthsis-9) from postnatal weeks 3 to 20. At each timepoint, renal disease progression and the mR NA expression of NF-κB-dependent genes(TNFa and CCL2) were determined. NF-κB was also histologicaly assessed in human PKD tissue.RESULTS: Progressive kidney enlargement in LPK rats was accompanied by increased renal cell proliferation and interstitial monocyte accumulation(peaking at weeks 3 and 10 respectively), and progressive interstitial fibrosis(with a smooth muscle actin and Sirius Red deposition significantly increased compared to Lewis kidneys from weeks 3 to 6 onwards). Rel/NF-κB proteins(phosphorylated-p105, p65, p50, c-Rel and RelB) were expressed in cystic epithelial cells(CECs) of LPK kidneys as early as postnatal week 3 and sustained until latestage disease at week 20. From weeks 10 to 20, nuclear p65, p50, Rel B and cytoplasmic IκBa protein levels, and TNFa and CCL2 expression, were upregulated in LPK compared to Lewis kidneys. NF-κB proteins were consistently expressed in CECs of human PKD. The DNA damage marker γ-H2AX was also identified in the CECs of LPK and human polycystic kidneys. CONCLUSION: Several NF-κB proteins are consistently expressed in CECs in human and experimental PKD. These data suggest that the upregulation of both the canonical and non-canonical pathways of NF-κB signaling may be a constitutive and early pathological feature of cystic renal diseases. | Michelle HT Ta Kristina G Schwensen David Liuwantara David L Huso Terry Watnick Gopala K Rangan | 2016 | World Journal of Nephrology2016，5，4： | 2 |
| 18 | Technetium 99mTc DTPA clearance in the evaluation of pulmonary involvement in patients with diabetes mellitus显示文摘 | Mousa K Onadeko BO Mustafa HT | 2000 | Respir Med2000，94，11： | 1 |
| 19 | The effect of dexamethasone on integrin and laminin expression in cultured human trabecular meshwork cells显示文摘 | Dickerson JE Jr Steely HT Jr English-Wright SL | 1998 | Exp Eye Res1998，66，： | 1 |
| 20 | Predictors of decline in MMSE scores among older Mexican Americans显示文摘 | Nguyen HT Black SA Ray LA | 2002 | J Geront Med Sci2002，57，3： | 1 |
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