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| 1 | 头颈癌化疗的Meta分析——93组17346例患者随机实验最新资料显示文摘Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients. Pignon JP, Maitre AL, Maillard E, et al. Radiother Oncol, 2009 May 14. | Pignon JP Matre AL Maillard E | 2009 | 中国口腔颌面外科杂志2009，7，4： | 79 |
| 2 | Epidemiology,determinants,and management of AIDS cholangiopathy:A review显示文摘Diseases of the liver and biliary tree have been described with significant frequency among patients with human immunodeficiency virus(HIV), and its advanced state, acquired immunodeficiency syndrome(AIDS). Through a variety of mechanisms, HIV/AIDS has been shown to affect the hepatic parenchyma and biliary tree, leading to liver inflammation and biliary strictures. One of the potential hepatobiliary complications of this viral infection is AIDS cholangiopathy, a syndrome of biliary obstruction and liver damage due to infection-related strictures of the biliary tract. AIDS cholangiopathy is highly associated with opportunistic infections and advanced immunosuppression in AIDS patients, and due to the increased availability of highly active antiretroviral therapy, is now primarily seen in instances of poor access to antiretroviral therapy and medication non-compliance. While current published literature describes well the clinical, biochemical, and endoscopic management of AIDS-related cholangiopathy, information on its epidemiology, natural history, and pathology are not as well defined. The objective of this review is to summarize the available literature on AIDS cholangiopathy, emphasizing its epidemiology, course of disease, and determinants, while also revealing an updated approach for its evaluation and management. | Maliha Naseer Francis E Dailey Alhareth Al Juboori Sami Samiullah Veysel Tahan | 2018 | World Journal of Gastroenterology2018，24，7： | 5 |
| 3 | Purified hematopoietic stem cells can differentiate into hepatocytes in vivo显示文摘 | Lagasse E Connors H Al - Dhalimy M | | 0，，： | 2 |
| 4 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015，21，18： | 2 |
| 5 | Micronucleus analysis in patients with colorectal adenocarcinoma and colorectal polyps显示文摘AIM:To determine,by counting micronucleus (MN) frequencies,whether chromosomal or DNA damage have an effect on the pathogenesis of early colorectal adenocarcinoma (CRC). METHODS:We analyzed MN frequencies in 21 patients with CRC,24 patients with colon polyps [10 neoplastic polyps (NP) and 14 non-neoplastic polyps (NNP)] and 20 normal controls. RESULTS:MN frequency was significantly increased in CRC patients and in NP patients compared with controls (3.72 ± 1.34,3.58 ± 1.21 vs 1.97 ± 0.81,P < 0.001). However,there was no difference in the MN frequency between CRC patients and NP patients (P > 0.05). Similarly,there was no difference in the MN frequency between NNP patients (2.06 ± 0.85) and controls (P > 0.05). CONCLUSION:Our results suggest increased chromosome/DNA instabilities may be associated with the pathogenesis of early CRC. | Ali Karaman Dogan Nas■r Binici Mehmet E■ref Kabalar Züleyha ■al■ku■u | 2008 | World Journal of Gastroenterology2008，14，44： | 2 |
| 6 | Inter-ethnic marriages and severity of coronary artery disease:A multicenter study of Arabian Gulf States显示文摘AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD. | Amin Daoulah Salem Al-kaabi Amir Lotfi Mushabab Al-Murayeh S Ali Nasseri Waleed Ahmed Salah N Al-Otaibi Mohamed N Alama Osama E Elkhateeb Amy J Plotkin Majed M Malak Khalid Alshali Mohamed Hamzi Saleh Al Khunein Mohammed Abufayyah Alawi A Alsheikh-Ali | 2017 | World Journal of Cardiology2017，9，4： | 2 |
| 7 | Maternal- fetal status of copper, iron, molybdenum, selenium and zinc in obese pregnant women in late gestation显示文摘 | Al - Saleh E Nandakumaran M Al - Harmi J | 2006 | Biol Trace Elem Res2006，113，： | 1 |
| 8 | Reflective Tomography Images from Range-resolved Laser Radar Measurements 显示文摘 | PARKER J K CRAIG E B KLICK D L el al | 1988 | Applied Optics1988，27，13： | 1 |
| 9 | Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF kappaB显示文摘 | Pozo Guisado E Merino J M Mulero-Navarro S el al | 2005 | Int J Cancer2005，115，1： | 1 |
| 10 | Complete computer system simulation: the SimOS approach显示文摘 | Rosenblum M Herrod S A Witchel E er al | 1995 | Parallel & Distributed Tectmology: Systems & Applications IEEE1995，3，4： | 1 |
| 11 | Effects of cinnamaldehyde, garlic and juniper berry essential oils on rumen fermentation, blood metabolites, growth performance, and carcass characteristics of growing lambs显示文摘 | Chaves A V Stanford K Dugan M E R eL al | 2008 | Livestock Science2008，117，23： | 1 |
| 12 | Platelet activation in pregnancy-induced hypertens-ion显示文摘 | Nadar SK AL Yemeni E | 2005 | Thromb Res2005，116，5： | 1 |
| 13 | Chartcteristics of heavy metal in contaminated soils显示文摘 | YALAGADDA P Y MATSUMOTO M R VANBENSCHOTEN J E Et al | 1995 | J Environ Eng1995，，121： | 1 |
| 14 | Mtitochondrion as a novel target of anticancer chemotherapy显示文摘 | Costanfirfi P Jacotot E Dccaudin D ct al | 2000 | J Natl Cancer Inst2000，92，13： | 1 |
| 15 | Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59显示文摘 | Hahn WC Menu E Bothwell AL | 1992 | Science1992，256，5065： | 1 |
| 16 | Efficacy of letrozole in the treatment of recurrent platinum-and taxane-resistant high-grade cancer of the ovary or peritoneum 显示文摘 | Ramirez PT Schmeler KM Milam MR e t al | 2008 | Gynecol Oncol2008，110，1： | 1 |
| 17 | Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex 显示文摘 | Hu ZY Zhang ZS Doo E Coux O Goldberg AL Liang TJ | 1999 | J Virol1999，73，9： | 1 |
| 18 | Add hack therapy in the treatment of endometriosis associated pain显示文摘 | Zupi E Marconi D Sbracia M el al | 2004 | Fertil Steril2004，82，5： | 1 |
| 19 | Human monocytederived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques显示文摘 | Shah PK Falk E Badimon J J et al | 1995 | Circulation1995，92，： | 1 |
| 20 | Developmental regulation of respiratory activity in pea leaves 显示文摘 | Lennon A M Pratt J Leach G e al | 1995 | Plant Physiol1995，107，： | 1 |
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