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| 1 | Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide显示文摘 | De MATTEO R MAY C N | 2003 | Br J Pharmacol2003，140，8： | 2 |
| 2 | Chronic hepatitis C virus infection:Serum biomarkers inpredicting liver damage显示文摘Currently, a major clinical challenge in the management of the increasing number of hepatitis C virus(HCV) infected patients is determining the best means for evaluating liver impairment. Prognosis and treatment of chronic hepatitis C(CHC) are partly dependent on the assessment of histological activity, namely cell necrosis and inflammation, and the degree of liver fibrosis. These parameters can be provided by liver biopsy; however, in addition to the risks related to an invasive procedure, liver biopsy has been associated with sampling error mostly due to suboptimal biopsy size. To avoid these pitfalls, several markers have been proposed as non-invasive alternatives for the diagnosis of liver damage. Distinct approaches among the currently available non-invasive methods are(1) the physical ones based on imaging techniques; and(2) the biological ones based on serum biomarkers. In this review, we discuss these approaches with special focus on currently available non-invasive serum markers. We will discuss:(1) class?Ⅰ?serum biomarkers individually and as combined panels, particularly those that mirror the metabolism of liver extracellular matrix turnover and/or fibrogenic cell changes;(2) class Ⅱ biomarkers that are indirect serum markers and are based on the evaluation of common functional alterations in the liver; and(3) biomarkers of liver cell death, since hepatocyte apoptosis plays a significant role in the pathogenesis of HCV infection. We highlight in this review the evidence behind the use of these markers and assess the diagnostic accuracy as well as advantages, limitations, and application in clinical practice of each test for predicting liver damage in CHC. | Pamela Valva Daniela A Ríos Elena De Matteo Maria V Preciado | 2016 | World Journal of Gastroenterology2016，22，4： | 2 |
| 3 | Surgical therapy formetastatic disease to the liver显示文摘 | Bentrem D J de Matteo R P Blumgart L H | 2005 | Ann Rev Med2005，56，： | 1 |
| 4 | Direct coronary vasodilator action of ad- renomedullin is mediated by nitric oxide 显示文摘 | De Matteo R May CN | 2003 | Br J Phamacol2003，140，8： | 1 |
| 5 | Staging, resectability, and outcome in 225 patients with cholangiocarcinoma 显示文摘 | Jamgin WR Fong Y De Matteo R | 2001 | Ann Surg2001，234，4： | 1 |
| 6 | Erythropoietin is neuropro- tective in a preterm ovine model ofendotoxin-induced brain in- jury 显示文摘 | Rees S Hale N De Matteo R | 2010 | J Neuropathol Exp Neurol2010，69，3： | 1 |
| 7 | Two hundred gastrointestinal stromal patterns and prognostic factors for survival 显示文摘 | De Matteo R Lewis JJ Leung D | 2000 | Ann Surg2000，231，1： | 1 |
| 8 | Erythropoietin is neuroprotec- tire in a preterm ovine model of endotoxin-induced brain injury显示文摘 | Rees S Hale N De Matteo R | 2010 | J Neuropathol Exp Neuro12010，69，3： | 1 |
| 9 | Inhibition of prostaglandin and nitric oxide synthesis prevents cortisol-induced renal vasodilatation in sheep显示文摘 | de Matteo R May C N | 1999 | Am J Physiol1999，276，42： | 1 |
| 10 | Two hundred gastrointestinalstromal tumor :recurrence patterns and prognostic factors for sur-vivaI显示文摘 | de Matteo R Lewis JJ Leung D | 2000 | Ann Surg2000，231，1： | 1 |
| 11 | Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide显示文摘 | De Matteo R May CN | 2003 | Br J Pharmacol2003，140，8： | 1 |
| 12 | Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide 显示文摘 | De Matteo R May CN | 2003 | Sr J Pharmacol2003，40，8： | 1 |
| 13 | Gastrointestinal stromal tumors and leiomyosarcoma of the abdomenan dretro- peritoneum: a chnical comparision 显示文摘 | Clary B M De Matteo R P Lewis J J | 2001 | Ann Surg Oncol2001，8，4： | 1 |
| 14 | Erythropoietin is neuroprotective in a preterm ovine model of endotoxin-induced brain injury 显示文摘 | Rees S Hale N De Matteo R | 2010 | Neuropathol Exp Neurol2010，69，3： | 1 |
| 15 | Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide显示文摘 | De Matteo R May CN | 2003 | Br J Pharmacol2003，140，8： | 1 |
| 16 | Erythropoi- etin protects the developing retina in an ovine model of endo- toxin-induced retinal injury显示文摘 | Loeligcr M M Mackintosh A De Matteo R | 2011 | Invest Ophthalmol Vis Sci2011，52，5： | 1 |
| 17 | Erythropoietin is neuroprotective in a preterm ovine model of endotoxin-induced brain injury显示文摘 | Rees S Hale N De Matteo R | 2010 | J Neuropathol Exp Neurol2010，69，3： | 1 |
| 18 | Diabetes is associated with increased perioperative mortality but equivalent long-term outcome after hepatic resection for colorectal cancer显示文摘 | Little S A Jarngagin W R De Matteo R P | 2002 | J Gastrointeat Surg2002，6，1： | 1 |
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