维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

5篇 您的检索式：作者名="de Graaf SS"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Vincristine induced apoptosis in acute lymphoblastic leukaemia cells:a mitochondrial controlled pathway regulated by reactive oxygen species? 显示文摘	Groninger E Meeuwsen-De Boer GJ De Graaf SS	2002	Int J Oncol2002，21，6：	1
	2	Vincristine-induced apoptosis in vivo in peripheral blood mononuclear cells of children with acute lymphoblastic leukaemia (ALL) 显示文摘	Groninger E de Graaf SS Meeuwsen-de Boer GJ	2000	Br J Haematol2000，111，3：	1
	3	Increasing the dosage of vincristine: a clinical and pharmacokinetic study of continuous-infusion vincristine in children with central nervous system tumors显示文摘BACKGROUND: Vincristine (VCR) is widely used to treat patients with malignant disease; among the patients treated with VCR are children with brain tumors. In vitro studies have demonstrated that the cytotoxic activity of VCR is related to both extracellular concentration and duration of exposure. The attainment of higher plasma concentrations by injecting larger bolus doses of VCR has been limited by concerns about neurotoxicity. One possible alternative strategy for enhancing the antitumor efficacy of VCR involves prolonging the duration of in vivo exposure. Therefore, the authors explored the neurotoxicity and pharmacokinetics of VCR administered via a 96hour continuous infusion after administration of a conventional bolus dose in a pediatric population. METHODS: The current study included 16 patients, 11 of whom were males. The median age of the study population was 4. 8 years (range, 1.7-15. 8 years).	Kellie SJ Koopmans P Earl J Nath C Roebuck D Uges DR De Graaf SS	2004	中国神经肿瘤杂志2004，2，2：	1
	4	Vin cristine induced apoptosis in acute lymphoblastic leukaemia cells:a mitochondrial controlled pathway regulated by reactive oxygen species? 显示文摘	Groninger E Meeuwsen-De Boer GJ De Graaf SS	2002	Int J 0ncol2002，21，6：	1
	5	Vincristine-induced apoptosis in vivo in peripheral blood mononuclear cells of children with acute lymphoblastic leukaemia (ALL) 显示文摘	Groninger E de Graaf SS Meeuwsen-de Boer GJ	2000	Br J Haematol2000，111，3：	1

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费