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| 1 | Glycogenic hepatopathy:A narrative review显示文摘Glycogenic hepatopathy(GH) is a rare complication of the poorly controlled diabetes mellitus characterized by the transient liver dysfunction with elevated liver enzymes and associated hepatomegaly caused by the reversible accumulation of excess glycogen in the hepatocytes. It is predominantly seen in patients with longstanding type 1 diabetes mellitus and rarely reported in association with type 2 diabetes mellitus. Although it was first observed in the pediatric population, since then, it has been reported in adolescents and adults with or without ketoacidosis. The association of GH with hyperglycemia in diabetes has not been well established. One of the essential elements in the pathophysiology of development of GH is the wide fluctuation in both glucose and insulin levels. GH and non-alcoholic fatty liver disease(NAFLD) are clinically indistinguishable, and latter is more prevalent in diabetic patients and can progress to advanced liver disease and cirrhosis. Gradient dual-echo MRI can distinguish GH from NAFLD; however, GH can reliably be diagnosed only by liver biopsy. Adequate glycemic control can result in complete remission of clinical, laboratory and histological abnormalities. There has been a recent report of varying degree of liver fibrosis identified in patients with GH. Future studies are required to understand the biochemical defects underlying GH, noninvasive, rapid diagnostic tests for GH, and to assess the consequence of the fibrosis identified as severe fibrosis may progress to cirrhosis. Awareness of this entity in the medical community including specialists is low. Here we briefly reviewed the English literature on pathogenesis involved, recent progress in the evaluation, differential diagnosis, and management. | Jagannath M Sherigar Joline De Castro Yong Mei Yin Debra Guss Smruti R Mohanty | 2018 | World Journal of Hepatology2018，10，2： | 7 |
| 2 | 西印度洋地区海草生态系统显示文摘海草是海洋被子植物,广泛分布在温带和热带的海岸带水域,是地球上水生生态系统中最具生产力的生物之一。在西印度洋地区大概有13种海草,这些海草覆盖了12000kg海岸线的近岸柔软海底广大区域。海草床一般分布在潮间带和潮下带,有时向下延伸至40m,并经常出现在珊瑚礁和红树林附近。由于具有很高的初级生产力和复杂的栖息环境,海草供养了许多底栖生物和浮游生物。许多鱼类和贝类,包括那些具有商业价值的种类都被吸引到海草栖息地,将海草作为其食物来源和避难场所,特别是在它们的幼年期。分布在西印度洋海草床附近广泛而丰富的鱼类资源就足以说明这一点。这些鱼分别属于天竺鲷科、亚科、玻甲鱼科、银鲈科、虾虎鱼科、隆头鱼科、裸颊鲷科、笛鲷科、单角亚科、鹦嘴鱼科、科、篮子鱼科、海龙科和Teraponidae科。因此,西印度洋地区的海草生态系统无论对当地还是整个地区的渔业发展都是非常有价值的资源。尽管如此,与其他地区相比,该地区有关海草资源的研究还十分缺乏,而且大多数研究也都集中在植物多样性和生态学上。本文主要阐述西印度洋地区海草床研究现状,特别强调鱼类和渔业。目前,该课题的大多数研究主要是在东非海岸开展的,如肯尼亚,坦桑尼亚,莫桑比克以及南非东部地区,而在索马里和西印度洋地区的岛屿国家(塞舌尔、科摩罗、法属留尼旺岛、毛里求斯、马达加斯加等)此类研究却很少,有关海草鱼类生态系统的论文也少有发表,而且大部分都是描述性的。因此,需要通过研究和实验获得有关描述模式和处理方法的科学知识。关于海草鱼类群落的定量研究,类似本文所介绍的案例研究在西印度洋地区是很少的,而这些研究对于渔业的管理前景而言是必不可少的。值得强调的是由于海岸人口的不断增长以及人类活动的侵扰给该地区海草床带来的压力与日俱增,如污染,海水富营养化,沉积作用,捕鱼以及无脊椎动物的采集等活动,而这些活动对于海草床的影响却鲜为人知。因此,需要开展广泛的研究,为西印度洋地区海草生态系统可持续管理提供有用的信息服务。 | Martin Gullstrm Maricela de la Torre Castro Salomo O.Bandeira Mats Bjrk Mattis Dahlberg Nils Kautsky Patrik Rnnbck Marcus C.hman 章任群 | 2002 | AMBIO-人类环境杂志2002，31，7： | 2 |
| 3 | Stress-induced 5-HT1A receptor desensitization: protective effects of Ginkgo biloba extract (EGb 761)显示文摘 | Bolanos-Jimenez F Manhaes de Castro R Sarhan H | 1995 | Fundam Clin Pharmacol1995，9，2： | 1 |
| 4 | Epigenetic modifications: basic mechanisms and role in cardiovascular disease 显示文摘 | Handy DE Castro R Loscalzo J | 2011 | Circulation2011，123，19： | 1 |
| 5 | Pneumococcal antimicro-bial resistance:therapeutic strategy and management in community-acquired pneumonia显示文摘 | Aspa J Rajas O de Castro F R | 2008 | Expert Opin Pharmacother2008，9，2： | 1 |
| 6 | Changes in growth, growth hormone, and insulin- like growth factor- 1 (IGF - 1) after orthotopic liver transplantation 显示文摘 | Infante D Tormo R Castro de Kolster C | 1998 | Pediatr Surg Int1998，13，56： | 1 |
| 7 | Sequential(step-by-step) detection,identification and quantization of extra virgin olive oil adulteration by chemo metric treatment of chromatographic profiles显示文摘 | CAPOTE F P JIMINEZ J R LUQUE de CASTRO M D | 2007 | Analytical and Bioanalytical Chemistry2007，338，8： | 1 |
| 8 | Role of follicle-stimulating hormone receptor Ser680Asn polymorphism in the efficacy of follicle-stimulating hormone显示文摘 | de Castro F Ruiz R Montoro L | 2003 | Fertil Steril2003，80，3： | 1 |
| 9 | Effect of container o- penings and airflow on energy required for forced air cool- ing of horticultural produce 显示文摘 | Castro (de) L R C Vigneault | 2005 | Canadian Biosystems En- gineering2005，47，： | 1 |
| 10 | Effect of container opening area on air distribution during precooling produce 显示文摘 | Castro de L R Vigneauh C Cortez L A B | 2004 | Transactions of the ASAE2004，47，6： | 1 |
| 11 | Differential responses of spinal axons ,to transection: influence of the NG2 proteoglycan 显示文摘 | De Castro R Jr Tajrishi R Claros J | 2005 | Exp Neurol2005，192，2： | 1 |
| 12 | Correlation between valsalva leak point pressure and maximal urethral closure pressure in women with stress urinary incontinence 显示文摘 | Feldner P C Jr Bezerra L R de Castro R A | 2004 | Int Urogynecol J Pelvic Floor Dysfunct2004，15，3： | 1 |
| 13 | Study of composition,stabilization and processing of wheat germ and maize industrial by-products显示文摘 | de Vasconcelos M C B M Bennett R Castro C | 2013 | Industrial Crops and Products2013，，2： | 1 |
| 14 | Cooling performance of horticultural produce in containers with peripheral openings 显示文摘 | Castro de L R Vigneault C Cortez L A B | 2005 | Postharvest Biology and Technology2005，38，3： | 1 |
| 15 | Astringency removal of ' Giombo' persimmon fruits submitted to different temperatures 显示文摘 | Antoniolli L R De Camargo e Castro P R Kluge R A | 2002 | Pesquisa Agropecuaria Brasileira2002，37，5： | 1 |
| 16 | Are plasma homocysteine concentrations in Brazilian adolescents in- fluenced by the intake of the main food sources of natural folate ? 显示文摘 | Bigio R S Verly E Jr de Castro M A | 2013 | Ann Nutr Metab2013，62，4： | 1 |
| 17 | A faulttolerant architectural approach for dependable systems显示文摘 | de Lemos R de Castro P A G Rubira C M | 2006 | IEEE Software2006，23，2： | 1 |
| 18 | Synergistic effects of agroindustrial wastes on simultaneous production of protease and α - amylase under solid state fermentation using a simplex centroid mixture design 显示文摘 | de Castro R S J Sato H H | 2013 | Industrial Crops and Products2013，49，： | 1 |
| 19 | Produce-simulator property evaluation for indirect airflow distribution measurement through horticultural crop package显示文摘 | Vigneault C Castro de L R | 2005 | Journal of Food Agriculture and Environment2005，3，2： | 1 |
| 20 | “Milk ofcalcium”: a rare presentation of calcinosis 显示文摘 | de Castro TC Ouamiero R Giacomin MF | 2014 | Rev BrasReumatol2014，54，1： | 1 |
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