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| 1 | Pathogenesis of hepatitis B virus infection显示文摘Infection with hepatitis B virus (HBV) leads to a wide spectrum of clinical presentations ranging from an asymptomatic carrier state to self-limited acute or fulminant hepatitis to chronic hepatitis with progression to cirrhosis and hepatocellular carcinoma. Infection with HBV is one of the most common viral diseases affecting man. Both viral factors as well as the host immune response have been implicated in the pathogenesis and clinical outcome of HBV infection. In this review, we will discuss the impact of virus-host interactions for the pathogenesis of HBV infection and liver disease. These interactions include the relevance of naturally occurring viral variants for clinical disease, the role of virus-induced apoptosis for HBV-induced liver cell injury and the impact of antiviral immune responses for outcome of infection. | Thomas F Baumert Robert Thimme Fritz von Weizscker | 2007 | World Journal of Gastroenterology2007，13，1： | 49 |
| 2 | 纤维素醚在水泥基干拌砂浆产品中的应用显示文摘纤维素醚特别是HPMC和HEMC在干拌砂浆产品中起着重要的作用。纤维素醚除了可保证干拌砂浆优异的和必不可少的保水性这一最基本的特性之外,还可使用改性的纤维素醚优化工作性和改善硬化砂浆的性能。 | L.Schmitz C-J.Hаcker 张量(译) | 2006 | 新型建筑材料2006，33，7： | 39 |
| 3 | 不同肝病患者抗肝抗原自身抗体的研究显示文摘目的 观察我国不同类型肝病患者中几种抗肝抗原自身抗体的存在状况 ;探讨自身免疫性肝脏疾病的自身抗体特征。方法 由 14 12例标本中选择 2 30例肝功能异常患者分为 5组 :①自身免疫性肝病组 4 2例 :自身免疫性肝炎 (AIH) 18例、原发性胆汁性肝硬化 (PBC) 2 1例、原发性硬化性胆管炎 (PSC) 3例。②HAV组 2 3例 ;③HBV组 70例 ;④HCV组 35例 ;⑤非甲~戊型肝炎组 6 0例。用间接免疫荧光、Westernblot、酶免疫条带技术等分别检测抗核抗体 (ANA)、抗线粒体抗体(AMA)、平滑肌抗体 (SMA)、肝肾微粒抗体Ⅰ型 (LKM 1)、肝细胞胞溶质抗原Ⅰ型 (LC 1)、可溶性肝抗原 (SLA) 肝胰抗原 (LP)和AMA M2亚型 ,以及SS A、SS B、dsDNA等多种抗体。结果 14 12例中诊断AIH、PBC和PSC者分别为送检标本的 1.2 7% ,1.4 9%和 0 .2 1%。 2 30例血清中 2例LKM 1阳性和 2例SLA LP阳性 ,分别见于AIH和HCV感染者。PBC患者AMA和M2全部阳性 ;其ANA以核膜型为主 (7 14 ) ;AIH患者ANA抗体未见特定的荧光类型 ,而抗 Actin仅见于AIH者。非甲~戊组 4例AMA和M2阳性 ,3例SMA高滴度阳性 ,4例出现SS A、SS B或dsDNA等抗体。结论 肝抗原抗体和ANA及AMA分型的检测有助于自身免疫性肝病和重叠多种免疫性肝病的诊断 ;非甲~戊型肝炎诊断时应? | 阎惠平 Winfried Stcker 贺立香 张世斌 李秀惠 黄德庄 赵春惠 | 2002 | 中华微生物学和免疫学杂志2002，22，5： | 30 |
| 4 | 孔隙率对Al_2O_3高孔隙率多孔介质EHC的影响显示文摘新型多孔介质燃烧技术主要采用泡沫陶瓷 ( Ceramic Foams)、波纹状陶瓷 ( Fabric LamellaStructure)等高孔隙率多孔介质。基于气、固相局部热平衡假设的有效导热系数 EHC( EffectiveHeat Conductivity)描述了气流与固体骨架中导热、弥散和热辐射多种传热方式的综合效果 ,是一个重要的传热特性 ,对其研究非常不足。通过实验与数值模拟确定不同孔隙率 Al2 O3 陶瓷的 EHC:基于测定的温度分布 ,给定 EHC的初值 ,采用有限体积法进行流场数值模拟 ;比较测量与计算的温度均方根差 ,通过对 EHC搜索寻优 ,间接确定泡沫陶瓷的有效导热系数。结果表明 Al2 O3 陶瓷的EHC随温度增加而增加 ,对速度不敏感 ;孔隙率高的陶瓷其 EHC较大。给出试样 EHC与温度和空管速度的拟合式 ;将颗粒床 EHC的 Z&B模型外推到 Al2 O3 高孔隙率陶瓷 ,并给出 | 潘宏亮 O.Pickena'非汉字符号'cker D.Trimis F.Durst | 2002 | 西北工业大学学报2002，20，3： | 8 |
| 5 | Prospective evaluation of small bowel preparation with bisacodyl and sodium phosphate for capsule endoscopy显示文摘AIM: To determine the effect of Prepacol?, a com- bination of sodium phosphate and bisacodyl, on transit and quality of capsule endoscopy (CE). METHODS: Fivety two consecutive patients were included in this prospective study. CE was performed following a 12 h fasting period. Twenty six patients were randomized for additional preparation with Prepacol?. The quality of CE was assessed separately for the proximal and the distal small bowel by 3 experienced endoscopists on the basis of a graduation which was initially developed with 20 previous CE. RESULTS: Preparation with Prepacol? accelerated small bowel transit time (262 ± 55 min vs 287 ± 97 min), but had no effect on the quality of CE. Visibility was significantly reduced in the distal compared to the proximal small bowel. CONCLUSION: The significantly reduced visibility of CE in the distal small bowel allocates the need for a good preparation. Since Prepacol? has no beneficial effect on CE the modality of preparation and the ideal time of application remains unclear. Further standardized examinations are necessary to identify sufficient preparation procedures and to determine the impact of the volume of the preparation solution. | Andreas Franke Frank Hummel Phillip Knebel Christoph Antoni Ulrich Bcker Manfred V Singer Matthias Lhr | 2008 | World Journal of Gastroenterology2008，14，13： | 5 |
| 6 | Supported ZnO catalysts for the conversion of alkanes:About the metamorphosis of a heterogeneous catalyst显示文摘ZnO could be a suitable catalyst for the oxidative conversion of CH4,C2H6 and C3H8.However,the main drawback is its thermal instability.Therefore,ZnO supported on ZrO 2,TiO2,γ-Al2O and SiO2 was investigated for the oxidative dehydrogenation of propane and ethane,and the oxidative coupling of methane.The stability of the supported ZnO is partially improved,but ZnO reacts with the support material,forming new compounds (Zn-zirconates,-titanates,-aluminates and-silicates),which already occurs below reaction temperature.This might also be the case for many other heterogeneous catalysts. | S.Arndt B.Uysal A.Berthold T.Otrebma Y.Aksu M.Driess R.Schomcker | 2012 | Journal of Natural Gas Chemistry2012，21，5： | 5 |
| 7 | The future of underground spatial planning and the resulting potential risks from the point of view of mining subsidence engineering显示文摘The topic of ground movements in Germany has been studied extensively in the past,especially in the field of active mines.The active hard coal mines in Germany were finally shut down in 2018 and lignite mining is expected to take place only until 2038.The so-called long-term liabilities of the mine operators in Germany include,among other things,the long-term guarantee of stability and thus the monitoring of ground motion.So far,the economic use of underground mining in Germany was mainly the supply of raw materials.In the future,the underground storage of compressed air,methane or hydrogen will play an important role in renewable energy supply and climate change.Therefore,the underground storage space will become more important and the spatial planning is essential to ensure availability of safe underground openings for the various options of environmentally friendly energy storage.However,this renewed usage of underground openings may also bring new and sometimes unknown challenges of geomechanical influence.The aftermath of hard coal and lignite mining will be an increasing challenge in mining subsidence engineering.On the other hand,new possibilities due to underground spatial planning may lead to subsidence and/or heaving of the upper surface. | Carolina Brücker Axel Preuβe | 2020 | International Journal of Mining Science and Technology2020，30，1： | 4 |
| 8 | 朊病毒显示文摘以前人们对此深信不疑,即所有的感染都是病原体如病毒、细菌或寄生虫等所致,这病原体有自身的DNA或RNA作为生物学功能和致病的遗传学基础。但是大约15年以前,旧金山加利福尼亚大学的Prusiner根据自己的观察。 | S.Wieland F.vonWeizs cker H.E.Blum 唐振亚 | 1997 | 德国医学1997，14，1： | 4 |
| 9 | Tumors of the papilla of Vater – inadequate diagnostic impact of endoscopic forceps biopsies taken prior to and following sphincterotomy显示文摘 | J. Menzel C. Poremba K.-H. Dietl W. B?cker W. Domschke | 1999 | Annals of Oncology1999，，10： | 3 |
| 10 | Biomechanics of posterior shoulder instability-current knowledge and literature review显示文摘Posterior instability of the shoulder is a rare condition and represents about 10% of shoulder instability. It has become more frequently recognized in the last year,even though it is more difficult to diagnose than anterior shoulder instability. As this form of shoulder pathology is somewhat rare,biomechanical knowledge is limited. The purpose of our study was to perform an extensive literature search,including PubMed and Medline,and to give an overview of the current knowledge on the biomechanics of posterior shoulder instability. The Pub Med/Medline databases were utilized,and all articles related to posterior shoulder instability and biomechanics were included to form a comprehensive compilation of current knowledge. A total of 93 articles were deemed relevant according to our inclusion and exclusion criteria. As expected with any newly acknowledged pathology,biomechanical studies on posterior shoulder instability remain limited in the literature. Current biomechanical models are performed in a static manner,which limits their translation for explaining a dynamic pathology. Newer models should incorporate dynamic stabiliza-tion of both the rotator cuff and scapulothoracic joint. There is a current lack of knowledge with regards to the pathomechanism of posterior shoulder instability,with no consensus on appropriate treatment regimens. Further investigation is therefore required at both basic science and clinical levels. | Henrik Constantin B?cker Samuel E Galle Mauro Maniglio Melvin Paul Rosenwasser | 2018 | World Journal of Orthopedics2018，9，11： | 2 |
| 11 | 货车车体的夹层结构显示文摘介绍了货车制造中夹层工艺的发展概况、被复和填充方法及其主要发展─“一次注料原地发泡”工艺。对冷藏车结构和具体结构系列以及有关环境保护和利废问题作了详细叙述。 | 吴月华 Bernhard Seidenstücker | 1996 | 国外机车车辆工艺1996，，5： | 2 |
| 12 | Postoperative Neurocognitive Dysfunction in Elderly Patients after Xenon versus Propofol Anesthesia for Major Noncardiac Surgery: A Double-blinded Randomized Controlled Pilot Study显示文摘 | Jan H?cker Claudia Stapelfeldt J?rn Leiendecker Patrick Meybohm Robert Hanss Jens Scholz Berthold Bein | 2009 | Anesthesiology2009，，5： | 2 |
| 13 | The effect of short time periods of pre‐operative warming in the prevention of peri‐operative hypothermia显示文摘 | E.‐P.Horn B.Bein R.B?hm M.Steinfath N.Sahili J.H?cker | 2012 | Anaesthesia2012，，： | 2 |
| 14 | The biology of cell locomotion within three-dimensional extracellular matrix显示文摘 | P. Friedl E.-B. Br?cker | 2000 | Cellular and Molecular Life Sciences2000，，1： | 2 |
| 15 | Shock wave lithotripsy versus ureteroscopy for distal ureteral calculi: a prospective study显示文摘 | P. Honeck A. H?cker P. Alken M. S. Michel T. Knoll | 2006 | Urological Research2006，，3： | 2 |
| 16 | 多孔介质中甲烷预混气火焰传播特性实验研究显示文摘本文对甲烷预混气在多孔介质中的火焰传播特性进行了实验研究,在开口竖直管中充填多孔介质,通过改变预混气氧含量使火焰在不同多孔介质中传播并测量火焰传播速度。预混气中氧含量最高达到29%。实验结果表明:多孔介质中甲烷可燃预混气火焰传播速度大于其层流火焰传播速度,可达到5倍以上(当量比的甲烷-空气预混气);多孔介质当量孔直径越大,或预混气层流火焰速度越高,则预混气火焰传播速度越高;多孔介质中可燃混气的火焰传播界限变小,当量孔直径大的多孔介质其界限值较大。实验结果与Babkin提出的多孔介质中的火焰传播机理相符。 | 潘宏亮 Picken(a|¨)cker O Trimis D Durst F | 2006 | 工程热物理学报2006，27，5： | 2 |
| 17 | Dependence of amygdala activation on echo time: results from olfactory fMRI experiments显示文摘 | St?cker T Kellermann T Schneider F | 2006 | Neuroimage2006，30，1： | 1 |
| 18 | Fertilizing effects of n-modified brown coal and its consequences to plant, soil and n- leaching losses 显示文摘 | Joachim K Klaus F Lutz B cker | 2003 | Archives of Agronomy and Soil Science2003，49，1： | 1 |
| 19 | Postoperative neuro-cognitive dysfunction in elderly patients after xenon versus propofolanesthesia for major noncardiac surgery:a double-blinded random-ized controlled pilot study显示文摘 | Hcker J Stapelfeldt C Leiendecker J | 2009 | Anesthesiology2009，110，5： | 1 |
| 20 | Methanol-to-hydrocarbons: Catalytic materials and their behavior显示文摘 | ST?CKER M | 1999 | Microporous Mesoporous Mater1999，29，12： | 1 |
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