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| 1 | Therapeutic effect of transcatheter arterial chemoembolization and percutaneous injection of acetic acids on primary liver cancer显示文摘BACKGROUND: The resection rate of primary liver tumor in China is only about 20%. A lot of patients with moderate and advanced liver tumor may lose the chance of opera- tion. The objective of present research was to study the ef- ficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous injection of chemical agents and acetic acids in the treatment of patients with primary liver cancer (PLC). METHODS: Thirty-three patients with middle and ad- vanced stage of PLC were divided into two groups: percu- taneous injection of chemical agents and acetic acids (15 patients, group A) and TACE (18 patients, group B). RESULTS: Tumor diameter and serum AFP level reduced to 86.6% and 83.3% in group A, and 55.5% and 40% in group B, respectively. There was significant difference be- tween the two groups ( P < 0 . 0 1 ) . The 1-, 2-, 3-, 4-year survival rates of group A were 96.7%, 86.6%, 51.3%, 33.3%, respectively and in group B were 66.7%, 44.4%, 16.7%, 0%, respectively (P<0.01). CONCLUSION: TACE combined with percutaneous injec- tion of chemical agents and acetic acids is efficacious to in- crease the survival rate of patients with PLC. | Hong-Bin Chen, Yue Huang, Dong-Ling Dai, Xia Zhang, Zhong-Wen Huang, Qi-Kai Zhang, Hui-Hua Wang, Jun-Su Zhang and Ge Pan Sanming, China Departments of Gastroenterology , Interventional Therapy , Ultrasonography and CT , Sanming Municipal First Hospital, Sanming 365000, China Department of Gastroenterology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400000, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，1： | 4 |
| 2 | The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein.显示文摘 | Chen TY Liu PH Ruan CT Chiu L Kung FL | 2006 | 中国生物学文摘2006，20，9： | 4 |
| 3 | Murine fertilized ovum, blastomere and morula cells lacking SP phenotype显示文摘In the field of stem cell research, SP (side population) phenotype is used to define the property that cells maintain a high efflux capability for some fluorescent dye, such as Hoechst 33342. Recently, many researches proposed that SP phenotype is a phenotype shared by some stem cells and some pro- genitor cells, and that SP phenotype is regarded as a candidate purification marker for stem cells. In this research, murine fertilized ova (including conjugate and single nucleus fertilized ova), 2-cell stage and 8-cell stage blastomeres, morulas and blastocysts were isolated and directly stained by Hoechst 33342 dye. The results show that fertilized ovum, blastomere and morula cells do not demonstrate any ability to efflux the dye. However, the inner cell mass (ICM) cells of blastocyst exhibit SP phenotype, which is consistent with the result of embryonic stem cells (ESCs) in vitro. These results indicate that the SP phenotype of ICM-derived ESCs is an intrinsic property and independent of the culture condition in vitro, and that SP phenotype is one of the characteristics of at least some pluripotent stem cells, but is not shared by totipotent stem cells. In addition, the result that the SP phenotype of ICM cells disap- peared when the inhibitor verapamil was added into medium implies that the SP phenotype is directly associated with ABCG2. These results suggest that not all the stem cells demonstrate SP phenotype, and that SP phenotype might act as a purification marker for partial stem cells such as some pluripo- tent embryonic stem cells and multipotent adult stem cells, but not for all stem cells exampled by the totipotent stem cells in the very early stage of mouse embryos. | XU YiXin1, HE ZhiYing2, ZHU HaiYing2, CHEN XueSong2, LI JianXiu2, ZHANG HongXia2, PAN XingHua3 & HU YiPing2 1 ChangZheng Hospital, affiliated to Second Military Medical University, Shanghai 200003, China 2 Department of Cell Biology, Second Military Medical University, Shanghai 200433, China 3 Department of Genetics, Yale University School of Medicine, New Haven, CT 06519, USA | 2007 | Science China(Life Sciences)2007，50，6： | 2 |
| 4 | Atrophy of the left dorsolateral prefrontal cortex is associated with poor performance in verbal fluency in elderly poststroke women显示文摘This study aimed to investigate the association between atrophy in the prefrontal cortex with executive function and verbal fluency in elderly male and female patients poststroke.Thirty elderly female patients with non-aphasic ischemic stroke aged ≥ 60 years and 30 age-matched non-aphasic male patients with ischemic stroke were recruited.Automatic magnetic resonance imaging segmentation was used to assess the volume of the whole prefrontal cortex,along with its subdivisions:anterior cingulate cortex,orbitofrontal cortex and dorsolateral prefrontal cortex.The Semantic Verbal Fluency Test was administered at 3 and 15 months poststroke.At 3 months poststroke,left dorsolateral prefrontal cortex volume was significantly correlated with Verbal Fluency Test score in female patients only(partial coefficient = 0.453,P = 0.045),after controlling for age,education,diabetes,neurological deficit,white matter lesions volume,as well as the location and volume of infarcts.At 15 months poststroke,there remained a significant association between the left dorsolateral prefrontal cortex volume and Verbal Fluency Test(partial coefficient = 0.661,P = 0.001) and between the left prefrontal cortex volume and Verbal Fluency Test(partial coefficient = 0.573,P = 0.004) in female patients after the same adjustments.These findings indicate that atrophy of the left dorsolateral prefrontal cortex contributes to the impairment of verbal fluency in elderly female patients with stroke.Sex differences may be present in the neuropsychological mechanisms of verbal fluency impairment in patients with stroke. | Yang-Kun Chen Wei-Min Xiao Defeng Wang Lin Shi Winnie CW Chu Vincent CT Mok Ka Sing Wong Gabor S Ungvari Wai Kwong Tang | 2013 | Neural Regeneration Research2013，8，4： | 2 |
| 5 | 显示文摘 | Chen SC Kuo PC Lie CT | 2001 | J Magn Magn Mater2001，236，： | 1 |
| 6 | Strengthening mecha-nisms of bone bonding to crystallinc hydroxyapatite in Vivo显示文摘 | Chen QZ Wong CT Lu WW | 2004 | Biomaterials2004，25，18： | 1 |
| 7 | Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery显示文摘 | Lin YH Mi FL Chen CT | 2007 | Biomacromolecules2007，8，1： | 1 |
| 8 | Comparisons of propafenone and sotalol as an initial treatment in patients with symptomatic paroxysmal atrial fibrillation显示文摘 | Lee SH Chen SA Tai CT | 1997 | Am J Cardiol1997，79，： | 1 |
| 9 | Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin显示文摘 | Chen CT Lin J Li Q | 2000 | Hum Gene Ther2000，11，14： | 1 |
| 10 | Porous chitosan microsphere for controlling the antigen release of newcastle disease vaccine preparation of antigen-absorbed microsphere and in vitro release显示文摘 | Mi FL Shyu SS Chen CT | 1999 | Biomaterials1999，20，17： | 1 |
| 11 | Emergence of an S gene mutant during thymosin alphal therapy in a patient with chronic hepatitis B 显示文摘 | TANG JH YEH CT CHEN TC | 1998 | J Infect Dis1998，178，： | 1 |
| 12 | Factors associated with bloodconcentrations of indoxyl sulfate and p-cresol in patients undergoingperitoneal dialysis显示文摘 | Lee CT Kuo CC Chen YM | 2010 | Perit Dial Int2010，30，4： | 1 |
| 13 | Assessment of reinforced poly(ethylene glycol) chitosan hydrogels as dressings in a mouse skin wound defect model显示文摘 | Chen SH Tsao CT Chang CH | 2013 | Mater Sci Eng C Mater Biol Appl2013，33，5： | 1 |
| 14 | Enviroumental friendly leaching reag~t for cobalt and lithium recovery from spent lithium-ion batteries 显示文摘 | LI L GE J CHEN R J ct al | 2010 | Waste Management2010，30，： | 1 |
| 15 | Effect of hydrogen sulphide on beta-amyloid-induced damage in PC12 cells 显示文摘 | Tang XQ Yang CT Chen J | 2008 | ClinExpPharma- colPhysiol2008，35，： | 1 |
| 16 | Molecular modding of flavonoids thaa inhibits xanthine oxidase显示文摘 | Lin CM Chen CS Chen CT | 2002 | Biochem Bioph Res Co2002，294，1： | 1 |
| 17 | Right atrial focal atrial fibrillation electrophysiologic characteristics and radiofrequency catheter ablation显示文摘 | Chen SA Tsai CT Yu WC | 1999 | J Cardiovasc Electrophysiol1999，10，： | 1 |
| 18 | Chinese kang as a domestic heating system in rural northern China-A review显示文摘 | Zhi Zhuang Yuguo Li Bin Chen ct al | 2009 | Energy and Building2009，2009，： | 1 |
| 19 | Morphometric Studies on the fishes of subfamily sparinne ( Perci-formes: Sparidae ) from the coastal waters of Taiwan显示文摘 | JEAN CT LEE SC CHEN CT | 1992 | Fish Soc: Taiwan1992，19，4： | 1 |
| 20 | Increased C-RK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas显示文摘 | Miller CT Chen G Gharib TG | | 0，，： | 1 |
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