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1Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome显示文摘AIM:To investigate the correlations between selfreported symptoms of irritable bowel syndrome(IBS) and the gastrointestinal(GI) microbiota composition.METHODS:Fecal samples were collected from a total of 44 subjects diagnosed with IBS.Their symptoms were monitored with a validated inflammatory bowel disease questionnaire adjusted for IBS patients.Thirteen quantitative real-time polymerase chain reaction assays were applied to evaluate the GI microbiota composition.Eubacteria and GI bacterial genera(Bifidobacterium,Lactobacillus and Veillonella),groups(Clostridium coccoides/Eubacterium rectale,Desulfovibrio desulfuricans) and distinct bacterial phylotypes [closest 16S rDNA sequence resemblance to species Bifidobacterium catenulatum,Clostridium cocleatum,Collinsella aerofaciens(C.aerofaciens),Coprococcus eutactus(C.eutactus),Ruminococcus torques and Streptococcus bovis ] with a suspected association with IBS were quantified.Correlations between quantities or presence/absence data of selected bacterial groups or phylotypes and various IBSrelated symptoms were investigated.RESULTS:Associations were observed between subjects' self-reported symptoms and the presence or quantities of certain GI bacteria.A Ruminococcus torques(R.torques)-like(94% similarity in 16S rRNA gene sequence) phylotype was associated with severity of bowel symptoms.Furthermore,among IBS subjects with R.torques 94% detected,the amounts of C.cocleatum 88%,C.aerofaciens-like and C.eutactus 97% phylotypes were significantly reduced.Interesting observations were also made concerning the effect of a subject's weight on GI microbiota with regard to C.aerofaciens like phylotype,Bifidobacterium spp.and Lactobacillus spp.CONCLUSION:Bacteria seemingly affecting the symptom scores are unlikely to be the underlying cause or cure of IBS,but they may serve as biomarkers of the condition.Erja Malinen Lotta Krogius-Kurikka Janne Nikkil Airi Palva Anna Lyra Anne Jskelinen Teemu Rinttil Terttu Vilpponen-Salmela Atte Johannes von Wright 2010World Journal of Gastroenterology2010,16,36:13
2Squamous cell carcinoma of the skin: Emerging need for novel biomarkers显示文摘The incidence of non-melanoma skin cancers(NMSC)is rising worldwide resulting in demand for clinically useful prognostic biomarkers for these malignant tumors,especially for invasive and metastatic cutaneous squamous cell carcinoma(cSCC).Important risk factors for the development and progression of cSCC include ultraviolet radiation,chronic skin ulcers and immunosuppression.Due to the role of cumulative long-term sun exposure,cSCC is usually a disease of the elderly,but the incidence is also growing in younger individuals due to increased recreational exposure to sunlight.Although clinical diagnosis of cSCC is usually easy and treatment with surgical excision curable,it is responsible for the majority of NMSC related deaths.Clinicians treating skin cancer patients are aware that certain cSCCs grow rapidly and metastasize,but the underlying molecular mechanisms responsible for the aggressive progression of a subpopulation of cSCCs remain incompletely understood.Recently,new molecular markers for progresprogression of cSCC have been identified.Atte Kivisaari Veli-Matti Kahari 2013World Journal of Clinical Oncology2013,4,4:5
3Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials显示文摘Antithrombotic Trialists’ (ATT) Collaboration 2009The Lancet . 2009 (9678)2009,,:2
4Recent diatom assemblage changes in subarctic Lake Saanaj?rvi, NW Finnish Lapland, and their paleoenvironmental implications显示文摘Sanna Sorvari Atte Korhola 1998Journal of Paleolimnology1998,,3:1
5Coagu lationalt erations in patients undergoing electivecraniotomy显示文摘Heesenm Kemke SM att hesb deinsber-gerw 1997Surg Neurol1997,47,:1
6Fracture resistance of single - tooth implant - supported all - ceramic restorations after exposure to the artificial mouth显示文摘Att W Kurun S Gerds T 2006J Oral Rehabil2006,33,:1
7Aspirin in the primary and secondary prevention of vascular disease : collaborative meta - analysis of individual participant data from randomised trials 显示文摘Antithrombotic Trialists' (ATT) Collaboration Baigent C Blackwell L 2009Lancet2009,373,9678:1
8Fracture resistance of single - tooth implant - supported all - ceramic restorations: an in vitro study显示文摘Att W Kurun S C erds T 2006J Prosthet Dent2006,95,:1
9Ultraviolet light-mediated photofunctionalization of titanium to promote human mesenchymal stem cell migration, attachment, proliferation and differentiation显示文摘Hideki Aita Wael Att Takeshi Ueno Masahiro Yamada Norio Hori Fuminori Iwasa Naoki Tsukimura Takahiro Ogawa 2009Acta Biomaterialia2009,,8:1
10种植支持无牙颌固定修复体材料对种植体及其修复体存留率的影响:系统性回顾及Meta分析显示文摘目的:评估无牙颌种植固定修复体的材料对其种植体及其修复体临床存留率的影响。文献检索:根据PRISMA声明(系统性回顾及Meta分析优先报告的条目).用电子数据库手动检索相关文献。检索范围为种植支持无牙颌固定修复体的临床研究,且研究的样本量不少于10人。本研究主要目的是评估不同修复体材料对种植体支持无牙颌固定修复种植体存留率及修复体存留率的影响。结果:共检索到文献2254篇.其中41篇文献入选。统计结果显示不同常用修复材料的无牙颌种植修复种植体存留率为:金属烤瓷修复体:97%(95%CI[0.96;0.98]).全瓷修复体:99%(95%CI[0.98;1.00]).金属烤塑修复体:97%(95%CI[0.96;0.98]).三组有显著性差异(P=0.0337)。而修复体存留率为:金属烤瓷修复体:95%(95%CI[0.89;0.97]).全瓷修复体:97%(95%CI[0.92;0.99]).金属烤塑修复体:97%(95%CI[0.95;0.98]).三者无显著性差异(P=0.3796)。三种修复体的饰面崩瓷率从低到高依次为金属烤瓷修复体:8%(95%CI[O.O30.20]).全瓷修复体15%(95%CI[0.06:0.32]).金属烤塑修复体:22%(95%CI[0.13;0.33])。进一步将修复体材料细分为5个亚组(非贵金属烤瓷,氧化错烤瓷.贵金属烤塑.非贵金属烤塑.PMMA)进行种植体及修复体存留率的统计。与上述结果类似.不同常用修复材料的种植体存留率有显著性差异(P=0.0126).而修复体存留率无显著性差异。结论:修复体材料的选择似乎对种植支持无牙颌固定修复的种植体及修复体存留率在临床上无明显影响。种植体支持的无牙颌修复体有较高的崩瓷率.仅修复体的存留率这一个参数难以描述该种修复材料实际的临床效果.参考价值有限。本研究纳入文献数量有限.在选择氧化错烤瓷或金属烤塑作为种植无牙颌修复体时,建议临床医师要慎重。Aimen Bagegni Samir Abou-Ayash Gerta Rucker Ahmad Algamy Wael Att 高文莫(译) 耿威(审) 2020中国口腔医学继续教育杂志2020,23,1:1
11Transition from microscopic to endoscopic transsphenoidal surgery for nonfunctional pituitary adenomas显示文摘Atte Karppinen Leena Kivipelto Sato Vehkavaara 2015World Neurosurgery2015,84,1:1
12Spectral re- flectance of silicon photodiodes 显示文摘Haapalinna Atte Karha Petri Ikonen Erkki 1998Applied Optics1998,37,4:1
13A method for calculating minimum biodiversity offset multipliers accounting for time discounting, additionality and permanence显示文摘Jussi Laitila Atte Moilanen Federico M. Pouzols 2014Methods Ecol Evol2014,,11:1
14Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randornised trials 显示文摘Antithrombotic Trialists'(ATT) Collaboration 2009Lancet2009,373,9678:1
15Oat bran b-gluco-and xylo-oligosaccharides as fermentative substrates for lactic acid bacteria显示文摘Pia Kontula Atte von Wright Tiina Mattila-Sandholm 1998International Journal of Food Microbiology1998,,45:1
16Antenatal causes of cerebral palsy:associations between inherited thrombophilias, vi- ral and bacterial infection, and inherited susceptibility to infection 显示文摘Gibson CS MacLennan Att GoldwateT PN 2003Obstet Gynecol Surv2003,58,3:1
17Marginal adaptation of all-ceramic crowns on implant abutments显示文摘Att W Hoischen T Gerds T 0,,04:1
18Tilted implants to support a maxillary removable dental prosthesis:a case report显示文摘Bateli M Woerner W Att W 2012Quintessence Int2012,43,3:1
19Prevention of allogeneic fetal reerection by tryptophan catabolism显示文摘Munn DH Zhou M Att Wood yr 1998Science1998,281,5380:1
20Does Doing Good Always Lead to Doing Better? Consumer Re- actions to Corporate Social Responsibility显示文摘SEN S BH ATT ACH AR YA C B 2001Jour- nal of Marketing Research2001,38,2:1
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