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| 1 | Polyethylene glycol microspheres loaded with irinotecan for arterially directed embolic therapy of metastatic liver cancer显示文摘AIM To study tumor response, and tolerability of arterially directed embolic therapy(ADET) with polyethylene glycol embolics loaded with irinotecan for the treatment of colorectal cancer liver metastases(CRC-LM). Secondary objectives were to monitor quality of life, time to progression and survival of patients.METHODS Patients were included in the study if they were affected by CRC-LM, refractory to systemic chemotherapy, treated with ADET using polyethylene glycol embolics, and had liver involvement < 50%. Tumor response, performance status(PS), tumor marker antigens, and quality of life(QoL) were monitored at 1, 3 and 6 mo after ADET. QoL was assessed with the Palliative Performance Scale(PPS).RESULTS We treated 50 consecutive CRC-LM patients with ADET using polyethylene glycol embolics. Their tumor response one month after ADET was: 28% of complete response(CR), 48% of partial response(PR), 8% stable disease(SD), and 16% of progression. Tumor response 3 mo after ADET was CR 24%, PR 38%, SD 19% and progression disease(PD) 19%. Tumor response 6 mo after ADET was CR 18%, PR 44%, SD 21% and PD 18%. QoL was 90% PPS at each time point. Median time to progression for patients who progressed was 2.5 mo(range 0.8-6). Median follow-up was 14 mo(0.8-25 range). ADETs were performed with no complications. Observed side effects(mild or moderate intensity) were: Pain in 32% of patients, increase of transaminase levels in 20% and fever in 14%, whereas 30% of patients did not complain any adverse event. CONCLUSION The treatment of unresectable CRC-LM with ADET using polyethylene glycol microspheres loaded with irinotecan was effective in tumor response and resulted in mild toxicity, and good QoL. | Giammaria Fiorentini Riccardo Carandina Donatella Sarti Michele Nardella Odysseas Zoras Stefano Guadagni Riccardo Inchingolo Massimiliano Nestola Alessandro Felicioli Daniel Barnes Navarro Fernando Munoz Gomez Camillo Aliberti | 2017 | World Journal of Gastrointestinal Oncology2017，9，9： | 6 |
| 2 | Intestinal bacterial translocation in rats with cirrhosis is related to compromised paneth cell antimicrobial host defense显示文摘 | Zora Teltschik Reiner Wiest Julia Beisner Sabine Nuding Claudia Hofmann Juergen Schoelmerich Charles L. Bevins Eduard F. Stange Jan Wehkamp | 2012 | Hepatology2012，，： | 2 |
| 3 | Thinning effects on walnut stem and crown diameter growth and fruiting in the walnut-fruit forests of Kyrgyzstan显示文摘The walnut-fruit forests(Juglans regia L.) in southern Kyrgyzstan are considered to be biodiversity hotspots and of considerable economic and ecological importance to local populations. The fruiting ability and stability of these forests are, however, decreasing because of infrequent silvicultural interventions and non-existent natural regeneration. Continuous inventories and walnut harvest measurements were carried out on 18 trial and control plots over the course of 13 year. Results showed that i) thinning had a positive influence on diameter at breast height(dbh) increase, ii) dbh growth and crown area increases are strongly and positively correlated, iii) large crowns enhanced the production of fruits, and iv) temperature conditions had a major influence on the production of fruits. The above-mentioned points are particularly relevant for young plantations but are also valid for relatively old plantations(> 50 years). We conclude that regular thinning substantially improves diameter growth, fruit production and ability of trees to withstand wind and snow damage in both young stands and in older walnut-fruit forests. | Jean-Pierre SORG Zora Lea URECH Davlet MAMADZHAN0V Maik REHNUS | 2016 | Journal of Mountain Science2016，13，9： | 2 |
| 4 | Ga doped SBA-15 as an active and stable catalyst for Friedel-Crafts liquid-phase acylation 显示文摘 | Zora E1 Berrichi Leila Cherif Orsen O | 2006 | Applied Catalysis A : Gene- ral2006，298，1： | 1 |
| 5 | Synthesis of ferrocenyl quinolines显示文摘 | ZORA M VELIOGLU O | 2008 | J Organomet Chem2008，693，： | 1 |
| 6 | Antioxidant capacity of lycopene-containing foods显示文摘 | Zora Djuric Lakesha C. Powell | 2001 | International Journal of Food Sciences and Nutrition2001，，： | 1 |
| 7 | Effect of soy isoflavone supplementation on markers of oxidative stress in men and women显示文摘 | Djuric Zora Chen Gang Doerge Daniel R | 2001 | Cancer Letters2001，172，1： | 1 |
| 8 | Role of Brassinosteroids, Ethylene, Abscisic Acid, and Indole-3-Acetic Acid in Mango Fruit Ripening显示文摘 | Sakimin Zaharah Zora Singh Gregory Symons James Reid | 2012 | Journal of Plant Growth Regulation2012，，3： | 1 |
| 9 | How It Feels to be Colored Me显示文摘 | Hurston Zora Neale | 1928 | The World Tomorrow1928，，： | 1 |
| 10 | Desmoid tumors of the head and neck:a therapeutic challenge显示文摘 | De BE Zoras O Hunt JL | 2014 | Head Neck2014，36，10： | 1 |
| 11 | Stable transformation of plastids in higher plants显示文摘 | ZORA S PETER H | 1990 | Proc Natl Acad Sci1990，87，： | 1 |
| 12 | 1-MCP regulates ethylene biosynthesisfruit softening during ripening of Tegan Blue,plum显示文摘 | AHMAD S KHAN ZORA S | 2007 | Postharvest BiolTechnol2007，43，2： | 1 |
| 13 | Earth-contact heat transfer: improvement and application of a novel simulation technique显示文摘 | Zoras S Davies M Wrobel L C | 2002 | Energy and Buildings2002，34，4： | 1 |
| 14 | Obturator hernia revisited:surgical anatomy,embryology,diagnosis,and technique of repair显示文摘 | Stamatiou D Skandalakis LJ Zoras O | | 0，，： | 1 |
| 15 | Postharvest oxidative behaviour of 1-methylcyclopropene treated Japanese plums ( Prunus salicina Lindell) during storage under controlled and modified atmospheres显示文摘 | Sukhvinder Pal Singh Zora Singh | 2012 | Postharvest Biology and Technology2012，，： | 1 |
| 16 | Effect of foliar and soil appli- cations of zinc sulphate on zinc uptake,tree size,yield,and fruit quality of mango 显示文摘 | BAHADUR L MALHI C S ZORA S | 1998 | Journal of Plant Nutrition1998，21，3： | 1 |
| 17 | Cross-talk between ER and HER2 in breast carcinoma显示文摘 | Zora N Dragica N | 2006 | Archive Oncol2006，14，14： | 1 |
| 18 | E - cadherin expression on fine - needle aspiration biopsies in primary lung adenocareinomas is related to tumor differentiation and invasion显示文摘 | Kalogeraki A Bouros D Zoras O | 2003 | Anticancer Res2003，23，4： | 1 |
| 19 | Postharvest Oxidative Behavior of 1-Methylcyclopropene Treated Japanese Plums (Prunus Salicina Lindell) During Storage under Controlled and Modi- fied Atmospheres显示文摘 | SUKHVINDER P S ZORA S | 2012 | Postharvest Biology and Technology2012，74，： | 1 |
| 20 | Obturator hernia revisited:surgical anatomy,embryology,diagnosis,and technique of repair显示文摘 | Stamatiou D Skandalakis LJ Zoras O | | 0，，09： | 1 |
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