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33篇 您的检索式:作者名="Zinner R"
    题名 作者 年代 出处 被引量
1吉非替尼治疗复治、晚期非小细胞肺癌的临床分析显示文摘目的:观察晚期非小细胞肺癌(NSCLC)患者接受吉非替尼(gefitinib)治疗后的生存期、缓解率、疗效。方法:分析2000年12月-2003年10月美国M.D.Anderson癌症治疗中心与上海市胸科医院接受吉非替尼250mg/d口服治疗的共175例晚期NSCLC患者。用Kaplan-Meier及logrank进行生存分析和比较,并用Cox多因素回归分析生存相关因素。用x^2检验比较不同因素在缓解率及疾病控制方面有无差异,logistic多因素回归分析疾病控制率、缓解率的相关因素。结果:175名患者的中位生存期(MST)为6.9个月(95%CI:4.19~9.61);中位无疾病进展时间(PFS)为3.47个月(95%CI:2.67~4.27)。Cox多因素分析显示性别(P=0.002)、年龄(P〈0.001)、治疗前血红蛋白水平(P=0.034)、PS评分(P=0.019)、既往化疗方案次数(P=0.013)、病理类型(P=0.030)是影响生存的独立因素。性别(P=0.002)、PS评分(P=0.013)是影响PFS的独立因素。所有患者的缓解率为10.14%;疾病控制率为40.54%。影响缓解率与疾病控制率的多因素分析提示性别(P=0.041)、年龄(P=0.035)、吸烟情况(P=0.038)是影响缓解率的独立因素,而性别是影响疾病控制率的独立因素(P=0.036)。结论:吉非替尼治疗复治、晚期NSCLC患者是安全、有效的。陆舜 李子明 虞永峰 廖美琳 ZINNER R 2006肿瘤2006,26,12:2
2Dose escalation of gem-citabine is possible with concurrent chest three-dimensionalrather than two-dimensional radiotherapy : a phase I trial inpatients with stage IE non-small-cell lung cancer 显示文摘Zinner RG Komaki R Cox JD 2009Int J Ra-dial Oncol Biol Phys2009,73,1:1
3Slow cooling of deep crustal granulite and Pb-loss in zircon 显示文摘Ashwal L D Tucker R D Zinner E K 1999Geochimica et Cosmochimica Acta1999,63,18:1
4Effect of Cu on the Evolution of Precipitation in an Fe-Cr-Ni-A1-Ti Maraging Steel显示文摘Schnitzer R Schober M Zinner S 2010ActaMaterialia2010,58,:1
5Crystal structures,spectroscopic,TG and DSC studies of lanthanide picrate complexes with 4-methylmorpholine N-oxide (MMNO)显示文摘FERNANDES L C MATOS J R ZINNER L B 2000Polyhedron2000,19,2223:1
6Histone lysine methylation patterns in human cell types are arranged in distinct three-dimensional nuclear zones显示文摘Zinner R Albiez H Walter J 2006Histochem CellBiol2006,125,:1
7Comparison of patient outcomes according to histology among pemetrexed-treated patients with stageⅢB/Ⅳnon-small-cell lung cancer in two phaseⅡtrials显示文摘Zinner R G Novello S Penq G 2010Clin Lung Cancer2010,11,2:1
8Duloxetine versus placebo in the treatment of stress urinary incontinence显示文摘Norton P A Zinner N R 2002American Journal of Obsterics and Gynecology2002,187,1:1
9Histone lysine methylation patterns in human cell types are arranged in distinct three dimensional nuclear zones显示文摘Zinner R Albiez H Walter J 2006Histochem cell Biol2006,125,122:1
10Trospium chloride improves overactive bladder symptoms:a multicenter phase Ⅲ trial显示文摘ZINNER N GITTELMAN M HARRIS R 2004J Urol2004,171,61:1
11Duloxetine versus placebo in the treatment of stress urinary incontinence (SUI)显示文摘Zinner N Dmochowski R Miklos J 2002Neurourol Urodyn2002,21,4:1
12Gemcitabine(G)with concurrent chest radiation(XRT)followed by consolidation chemotherapy with gemcitabine plus cisplatin(CDDP):a phase I trial for patients with stage Ⅱ non-small cell lung cancer (NSCLC)显示文摘 Zinner RG Komaki R 2001Proc Am Soc Clin Oncol2001,20,:1
13Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin 显示文摘Illner D Zinner R Handtke V Rouquette J Strickfaden H Lanctot C Conrad M Seller A Imhof A Cremer T Cremer M 2010Exp Cell Res2010,316,10:1
14Lilhium, Boron and Sulphur Isotopic Ratios in Large Presol- ar SiC G-rains From Murchison显示文摘GYNGARD F AMARI S ZINNER E GALLINO R LEWIS R S 2007Lunar and Planetary Science XXXIH2007,38,:1
15Phase Ⅱ study of pemetrexed in combination with carboplatin inthe first-line treatment of advanced nonsmall cell lung- cancer显示文摘Zinner R G Fossella F V Gladish G W 2005Cancer2005,104,:1
16Duloxetine Versus Placebo in the Treatment of Stress Urinary Incontinence显示文摘Norton Peggy A Zinner Norman R 2002American Journal of Obsterics and Gynecology2002,187,1:1
17Samples of stars beyond the solar system : Silicate grans in interplanetary dust显示文摘Messenger S Keller L P Stademann F J Walker R M Zinner E 2003Science2003,300,:1
18Stellar sapphires: The properties and origins of presolar A1203 in mete- orites显示文摘Nittler L R Alexander C M OD Gao X Walker R M Zinner E 1997Astrophys J1997,483,:1
19Effect of Cu on the evolution of precipitation in an Fe Cr Ni A1 Ti maraging steel显示文摘Schnitzer R Schober M Zinner S 2010Acta Materialia2010,58,10:1
20The novel and effective nonplatinum, nontaxane combination of gemcitabine and vinorelbine in advanced non-small cell lung carcinoma: Potenial for decreased toxicity and combination with biological therapy 显示文摘 Khuri FR Lu C Liu DD Fossella FV Glisson BS Pisters Km Shin DM Papadimitrakopoulou VA Kurie JM Blumenschein G Jr Kies MS Zinner R Jung MS Lu R Lee JJ Munden RF Hong WK Lee JS 2002Cancer2002,95,2:1
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