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| 1 | Structural shifts of mucosa-associated lactobacilli and Clostridium leptum subgroup in patients with ulcerative colitis显示文摘 | Zhang ML Liu BY Zhang Y Wei H Lei YF Zhao LP | 2007 | 中国生物学文摘2007，21，8： | 14 |
| 2 | Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer显示文摘AIM: To compare the clinicopathological features of patients with non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.METHODS: All the patients with rectosigmoid carcinoma who underwent laparoscopic radical surgical resection in the Shanghai Minimally Invasive Surgical Center at Ruijin Hospital affiliated to Shanghai JiaoTong University between October 2009 and October2013 were included in this study. Twenty-six cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected. Symptoms,endoscopic findings and clinicopathological characteristics were evaluated retrospectively.RESULTS: There were no significant differences between patients with and without schistosomiasis in gender, age, CEA, CA19-9, preoperative biopsy findings or postoperative pathology. Patients with rectosigmoid schistosomiasis had a significantly higher CA-125 level and a larger proportion of these patients were at an early tumor stage(P = 0.003). Various morphological characteristics of schistosomiasis combined with rectosigmoid cancer could be found by colonoscopic examination: 46% were fungating mass polyps, 23%were congestive and ulcerative polyps, 23% were cauliflower-like masses, 8% were annular masses.Only 27% of the patients were diagnosed with rectal carcinoma preoperatively after the biopsy. Computed tomography(CT) scans showed thickened intestinal walls combined with linear and tram-track calcifications in 26 patients.CONCLUSION: Rectosigmoid carcinoma combined with schistosomiasis is associated with higher CA-125 values and early tumor stages. CA-125 and CT scans have a reasonable sensitivity for the accurate diagnosis. | Hao Feng Ai-Guo Lu Xue-Wei Zhao Ding-Pei Han Jing-Kun Zhao Lei Shi Tobias S Schiergens Serene ML Lee Wen-Peng Zhang Wolfgang E Thasler | 2015 | World Journal of Gastroenterology2015，21，23： | 6 |
| 3 | P53 codon 72 polymorphism contributes to breast cancer risk: a metaanalysis based on 39 case-control studies(摘要)显示文摘 | Zhang, ZZ Wang, ML Wu, DM Wang, MM Tong, N Tian, YY Zhang, ZD | 2010 | 南京医科大学学报(自然科学版)2010，30，7： | 3 |
| 4 | FKBP23 in ER binds to BiP specifically显示文摘FKBP23 was found in mouse endoplasmic reticulum (ER) in 1998. It consists of an N-terminal peptidyl-prolyl cis-trans isomerase (PPIase) domain and a C-terminal domain with Ca2+ binding sites. The fusion protein of mouse FKBP23 and glutathione S-transferase (GST), GST-FKBP23, and the fusion protein of BiP, a member of heat shock protein 70 (Hsp 70) in ER, and GST, GST-BiP, were subcloned in E. coli, expressed and purified. The fusion proteins were restrictively digested by Factor Xa (FaXa) to obtain the free cloned proteins FKBP23 and BiP. With the assay of adsorption of free FKBP23 or BiP with GST-BiP or GST-FKBP23 attached to the Glutathione-Sepharose 4B, the adsorbed FKBP23 or BiP could be detected by Immunoblot. It means that FKBP23 binds to BiP. Furthermore, BiP in leukocyte ER-extract can be adsorbed with GST-FKBP23 attached to the glutathione-Sepharose 4B. It shows that FKBP23 binds to natural BiP in ER, too. These experiments show that a PPIase binds to a molecular chaperone of the Hsp70 family. | ZHANG Wanqi, LI Hui, ZHANG Xiaobin, SHEN Ye, WANG Yinong, Ml Huaifeng & HE BinglinState Key Laboratory of Functional Polymer Materials for Adsorption and Separation, Chemical School of Nankai University, Tianjin 300071, China Hygienic School of Tianjin Medical University, Tianjin 300071, China Medical School of Nankai University, Tianjin 300071, China | 2004 | Science China Chemistry2004，47，1： | 2 |
| 5 | Prenatal diagnosis of thalassemia: experiences at the Shanghai Children's Hospital显示文摘 | ZENG YT HUANG SZ ZHANG ML | 1988 | Hemoglobin1988，12，5： | 1 |
| 6 | Association between myeloperoxidase levels and risks of coronary atery disease显示文摘 | Zhang R Brennan ML Fu X | 2001 | JAMA2001，28，6： | 1 |
| 7 | Laboratory studies of berberine used alone and in combination with 1,3-bis(2-chloroethyl)-1-nitrosourea to treat malignant brain tumors显示文摘 | Zhang RX Doughterty DV Rosenblum ML | 1990 | Chin Med J1990，103，8： | 1 |
| 8 | Human gastric tissues simultaneous-ly express the classical and alternative splicing cholecystokinin-B/gastrin receptors显示文摘 | Zhuo JJ Chen ML Zhang QZ | 2004 | Receptors Channel2004，10，56： | 1 |
| 9 | Enhanced biohydrogen production from cornstalk wastes with acidification pretreatment by mixed anaerobic cultures显示文摘 | Zhang ML Fan YT Xing Y | 2007 | Biomass and Bioenergy2007，31，4： | 1 |
| 10 | Cx43 in mesenchymal stem cells promotes angiogenesis of the infarcted heart independent of gap junctions显示文摘 | WANG DG ZHANG FX CHEN ML et ol | 2014 | Mol Med Rep2014，9，4： | 1 |
| 11 | Transformation of several vegetable crops by Agrobacterium rhizogenes 显示文摘 | WANG FJ ZHANG LM CUI ML | 1992 | BeijingProc Asia- Pacific Confon Agri Biot1992，，： | 1 |
| 12 | Association between myeloperoxidase levels and risk of coronary artery disease 显示文摘 | Zhang R Brennan ML Fu X | 2001 | JAMA2001，286，17： | 1 |
| 13 | Simultaneous detection of multiple genetic aberrations in single cells by spectral fluorescence in situ hybridization显示文摘 | Slovak ML Tcheurekdjian L Zhang FF | 2001 | Cancer Res2001，61，3： | 1 |
| 14 | The α5β1 integrin mediates elimination of amyloid-β peptide and protects against apoptosis显示文摘 | Zhang Z Nordstedt C | 1998 | J Cell Biol1998，141，4： | 1 |
| 15 | Analysis of intestinal bacterial community diversity of adult Dastarcus helophoroides 显示文摘 | Zhang ZQ He C Li ML | 2014 | Journal of Insect Science2014，，14： | 1 |
| 16 | Knockdown of NYGGF4 increases glucose transport in C2C12 mice skeletal myocytes by activation IRS-1/PI3K/AKT insulin pathway 显示文摘 | Zeng XQ Zhang CM Tong ML | 2012 | J Bioenerg Biomembr2012，44，3： | 1 |
| 17 | Osthole improves fat milk- induced fatty liver in rats: modulation of hepatic PPAR- alpha/gamma-mediated lipogenic gene expression 显示文摘 | Zhang Y Xie ML Xue J | 2007 | Plant Med2007，73，8： | 1 |
| 18 | Macrophage migration inhibitory factor contributes to hypoxic pulmonary vasoconstriction in rats 显示文摘 | Zhang B Luo Y Liu ML | 2012 | Microvasc Res2012，83，2： | 1 |
| 19 | Partial scapulectomy for congenital elevation of the scapula 显示文摘 | Zhang ZM Zhang J Lu ML | 2007 | Clin Orthop Relat Res2007，457，： | 1 |
| 20 | Improved refractory wound healingwith administration of acidic fibroblast growth factor in diabetic rats显示文摘 | Xie LY Zhang ML Dong BJ | 2011 | Diabetes Research and Clinical Practice2011，93，3： | 1 |
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