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| 1 | Antimicrobial resistance of abnormal vaginal discharges microorganisms in Ouagadougou,Burkina Faso显示文摘Objective:To assess the prevalence of bacterial strains and fungal strains infecting the vaginal tract and test their sensitivity to antibiotics in women attending Saint Camille Medical Centre in Ouagadougou.Methods:From January 2008 to December 2009,a total of 2000 vaginal swabs were cultivated for bacterial and fungal identification and isolation.Furthermore,bacterial strains were tested for their susceptibility to several antibiotics used in routine in the centre. Results:The results revealed that microbial isolation and identification was attempted for 1536/2000 sample,a positivity rate of 76.80%.Candida albicans(48.76%),followed by Escherichia coli(16.67%),Streptococcus agalactiae(8-14%) and Staphylococcus aureus(7.55%) were the major agents of genital tract infections in patients.Mycoplasma hominis and Ureaplasma urealyticum combined accounted for less than 7%.Trichomonas vaginalis was identified in 1.04%coses.The antimicrobial tests revealed that the microorganisms developed resistance to several antibiotics including beta lactams.However,antibiotics such as cefamenzol,ciprofloxacin and norfloxacin were still active on these bacteria.Conclusions:The results reveal that many sexually active women are infected by one or more microbial pathogens,probably because of the lock of hygiene or the adoption of some risky behaviors,such as not using condoms or having multiple sexual partners.Efforts should be made to address these points in the country. | Simplice D Karou Florencia Djigma Tani Sagna Christelle Nadembega Moctar Zeba Aboudoulaye Kabre Kokou Anani Djeneba Ouermi Charlemagne Gnoula Virginio Pietra Salvatore Pignatelli Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 2 |
| 2 | Role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in cryoballoon ablation outcomes for paroxysmal atrial fibrillation显示文摘BACKGROUND Cryoballoon ablation(CBA)is recommended for patients with paroxysmal atrial fibrillation(AF)refractory to antiarrhythmic drugs.However,only 80%of patients benefit from initial CBA.There is growing evidence that pretreatment with angiotensin-converting enzyme inhibitors(ACEIs)and angiotensin receptor blockers(ARBs)decreases the recurrence of AF postablation,particularly in nonparoxysmal AF undergoing radiofrequency ablation.The role of ACEIs and ARBs in patients with paroxysmal AF in CBA remains unknown.We decided to investigate the role of ACEIs and ARBs in preventing the recurrence of atrial arrhythmia(AA)following CBA for paroxysmal AF.AIM To investigate the role of ACEIs and ARBs in preventing recurrence of AA following CBA for paroxysmal AF.METHODS We followed 103 patients(age 60.6±9.1 years,29%women)with paroxysmal AF undergoing CBA 1-year post procedure.Recurrence was assessed by documented AA on electrocardiogram or any form of long-term cardiac rhythm monitoring.A multivariable Cox proportional hazard model was used to assess if ACEI or ARB treatment predicted the risk of AA recurrence.RESULTS After a 1-year follow-up,19(18.4%)participants developed recurrence of AA.Use of ACEI or ARB therapy was noted in the study population.Patients on ACEI/ARB had a greater prevalence of hypertension and coronary artery disease.On a multivariate model adjusted for baseline demographics and risk factors for AF,ACEI or ARB therapy did not prevent recurrence of AA following CBA(P=0.72).Similarly,on Kaplan–Meier analysis pretreatment with ACEI/ARB did not predict the time to first recurrence of AA(P=0.2173).CONCLUSION In our study population,preablation treatment with an ACEI or ARB had no influence on the recurrence of AA following CBA for paroxysmal AF. | Ibragim Al-Seykal Abhishek Bose Parag A Chevli Zeba Hashmath Nitish Sharma Ajay K Mishra Douglas Laidlaw | 2022 | World Journal of Cardiology2022，14，10： | 2 |
| 3 | Effect of iron or multiple micronutrient supplements on the prevalence of anaemia among anaemic young children of a malariaendemic area: a randomized double-blind trial显示文摘 | Ouedraogo HZ Dramaix-Wilmet M Zeba AN etal | 2008 | Trop Med Int Health2008，13，10： | 1 |
| 4 | Ablation characteristics of an aromatic thermosetting copolyester/carbon fiber composite显示文摘 | Zeba parkar Chris Mangun | 2012 | J Composite Materials2012，46，15： | 1 |
| 5 | Effect of iron or multiple micronutrient supplements on the prevalence of anaemia a- mong anaemic young children of a malariaendemic area : A randomized double-blind trial 显示文摘 | OUEDRAOGO HZ DRAM ALM ZEBA AN | 2008 | Trop Med Int Health2008，13，10： | 1 |
| 6 | Bi- omechanical analysis of women weightlifters during the snatch 显示文摘 | Hoover DL Carlson KM Christensen BK Zebas CJ | 2006 | J Strength Cond Res2006，20，3： | 1 |
| 7 | IND-6, a highly diver- gent 1ND-type metallo-lactamase from Chryseobacterium indologe- nesstrain 597 isolated in BurkinaFaso 显示文摘 | Zeba B Deluea F Delmareelle M | 2009 | Antimicrob Agents Che- mother2009，53，10： | 1 |
| 8 | Influence of Periopera- tive Administration of Amino Acids on Thermoregulation Re- sponse in Patients Underwent Coloreetal Surgical Procedures 显示文摘 | Zeba S Surbatovic M Jevtic' M | 2007 | Vojnosanit Pregl2007，64，6： | 1 |
| 9 | Prospective Evaluation of Efficacy and Toxicity of 5 -Fu and Folinic Acid (Mayo Regimen ) in Patients With Advanced Cancer of the Galbladder 显示文摘 | Malik IA Aziz Zeba | 2003 | Am J Clin Oncol2003，26，2： | 1 |
| 10 | Heat-inducible C3HC4 type RING zinc finger protein gene from Capsicum annuum enhances growth of transgenic tobacco显示文摘 | ZEBA N ISBAT M KWON N J | 2009 | Planta2009，229，4： | 1 |
| 11 | Prevalence and genotype characterization of Human Papillomaviruses among HIV-seropositive in Ouagadougou, Burkina Faso显示文摘 | F.W. Djigma C. Ouédraogo D.S. Karou T. Sagna C. Bisseye M. Zeba D. Ouermi C. Gnoula V. Pietra N.W. Ghilat-Avoid-Belem K. Sanogo J. Sempore S. Pignatelli A.M. Ferri J.-B. Nikiema J. Simpore | 2010 | Acta Tropica2010，，3： | 1 |
| 12 | A Bax inhibitor-1 gene in Capsicum annuuna is induced under various abiotic stresses and endows multi-tolerance in transgenic tobacco 显示文摘 | Isbat M Zeba N Kim S R Hong C B | 2009 | Plant Physiol2009，166，： | 1 |
| 13 | IND - 6, a highly divergent IND -type metallo -lactamase from Chryseobacterium indologenesstrain 597 isolated in BurkinaFaso 显示文摘 | ZEBA B DELUCA F DELMARCELLE M | 2009 | Antimicrobial Agents and Chemotherapy2009，53，10： | 1 |
| 14 | A Bax inhibitor-I gene in Capsicum annuum is induced under various abiotic stresses and endows multi-tolerance in transgenic tobacco 显示文摘 | Isbat M Zeba N Kim S R Hong C B | 2009 | Plant Physiology2009，166，： | 1 |
| 15 | Effect of iron or multiple micronutrient supplements on the prevalence of anaemia among anaemic young children of a malariaendemic area:a randomized double -blind trial显示文摘 | Ouedraogo HZ Dramaix-Wilmet M Zeba AN | 2008 | Trop Med Int Health2008，13，10： | 1 |
| 16 | A BAX inhibitor-1 gene in Capsicum annuum is induced under various abiotic stresses and endows multi-tolerance in transgenic tobacco 显示文摘 | Isbat M Zeba N Kim SR Hong CB | 2009 | Plant Physiology2009，166，15： | 1 |
| 17 | National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma显示文摘A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the experts.The Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this meeting.This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these patients.This coordinated effort can minimise delays and give patients a chance for curative treatment and effective palliation.The diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance cholangiopancreato-graphy.Brush cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for diagnosis.However,histopathologic confirmation is not always required before resection.Endoscopic ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for staging.The only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette classification.Selected patients with unresectable hCCA can be considered for liver transplantation.Adjuvant chemotherapy should be offered to patients with a high risk of recurrence.The use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary discussions.Patients with acute cholangitis can be drained with endoscopic or percutaneous biliary drainage.Palliative chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA. | Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed | 2024 | World Journal of Gastroenterology2024，30，9： | 0 |
| 18 | Heteropoly Ionic Liquid Functionalized MOF-Fe:Synthesis,Characterization,and Catalytic Application in Selective Acetalization of Glycerol to Solketal as a Fuel Additive at Room Temperature,Solvent-Free Conditions显示文摘In this work,we have reported the synthesis of a series of heterogeneous catalysts,viz.,[HMIm]_(3)[PW_(12)O_(40)]@MOF-Fe,[HMIm]_(3)[PMo_(12)O_(40)]@MOF-Fe,and[HMIm]_(4)[SiW_(12)O_(40)]@MOFFe,by a simple impregnation method.The catalysts were characterized by several techniques,such as FTIR,EDX,XRD,SEM,elemental mapping,and TGA.Among these materials,[HMIm]_(3)[PW_(12)O_(40)]@MOF-Fe had more acidic sites(confirmed by potentiometric titration)and high stability around 598℃(confirmed by TGA).The catalytic prospect of the materials was examined through selective acetalization of glycerol to solketal as a fuel additive under solvent-free and room-temperature conditions.[HMIm]_(3)[PW_(12)O_(40)]@MOF-Fe exhibited the highest catalytic activity among the three catalysts in terms of glycerol conversion(100%),solketal selectivity(100%),and solketal yield(100%).A recyclability study of[HMIm]_(3)[PW_(12)O_(40)]@MOF-Fe showed that the material could be reused for up to 7 cycles with insignificant loss in its catalytic performance. | Abdulaziz Abdullah Qasem Ali Zeba N.Siddiqui | 2023 | Precision Chemistry2023，1，8： | 0 |
| 19 | Epidemiology of antibiotic resistance in Burkina Faso显示文摘Burkina Faso(West Africa) is a tropical country with a high incidence of infectious diseases.The uncontrolled use of antibiotics against bacterial pathogens has given rise to the emergence of antibiotic resistance in this country.The aims of this study were;i) to determine the prevalences of the most important pathogenic bacteria isolated in the town of Ouagadougou;ii) to identify the bacterial species which have acquired resistance as a result of antibiotic selection;iii) to compare antibiotic-resistances of Escherichia coli isolated from stool culture in the present study with results obtained in 2002 from strains collected in the same structure in Burkina Faso;iv) to determine the trend of antibiotic resistance in Burkina Faso in order to give local advice on the most appropriate empiric antibiotic therapy.Six thousand two hundred and sixty four samples of blood,stools, urine,sputum,pus and vaginal secretion were collected and analyzed in Saint Camille Medical Center(SCMC) laboratory from May 2001 to May 2006.Out of the 6264 samples tested no pathogen was identified in 1583(25.31%),whilst 4681(74.73%) were positive with the incidence of the microrganisms isolated being as follows;Escherichia coli 1291(27.6%),Staphylococcus aureus 922(19.7%),Salmonella spp 561(12. 0%),Streptococcus spp 499(10.7%),Klebsiella spp 359(7.7%),Shigella spp(6.3%),Acinetobacter spp 266(5.7%) and others 783(16.7%).Among the isolated pathogens,the highest resistance was found to amoxicillin:Proteus spp 95,6%,Escherichia coli 78,2%,Salmonella spp 62,2%,Shigella spp 73,4% and Klebsiella spp 89,9%,followed by resistance to ampicillin and cotrimoxazole.Comparing the prevalence of antibiotic resistance of Escherichia cob’from stool cultures isolated during 1999-2000 to that of 2001-2006, a significant reduction was found which could be due to the improved use of antibiotics in recent years.The reduced antibiotic-resistance observed in pathogens isolated in Burkina Faso during this study as compared to previous data,could be the result of setting up microbiological epidemiological monitoring centres,in tropical countries,to better control the emergence of bacterial antibiotic-resistance. | Simpore J Zeba B Karou D Ilboudo D Pignatelli S Nacoulma OG Musumeci S | 2008 | Asian Pacific Journal of Tropical Medicine2008，1，2： | 0 |
| 20 | Cancer Cell:新型药物组合或有望治疗恶性白血病显示文摘近日,刊登在国际杂志Cancer Cell上的一篇研究报告中,来自马里兰大学医学院等机构的研究人员开发了一种新型药物组合或有望帮助治疗急性髓性白血病(AML),在诊断为该疾病后,舭能在5年内使得几乎四分之三的患者死亡。目前在美国三个研究中研究研究人员正在招募研究者进行多中心的临床试验。 | Nidal E. Muvarak Khadiza Chowdhury Limin Xia Carine Robert Eun Yong Choi Yi Cai Marina Bellani Ying Zou Zeba N. Singh Vu H. Duong Tyler Rutherford Pratik Nagaria S?ren M. Bentzen Michael M. Seidman Maria R. Baer Rena G. Lapidus Stephen B. Baylin Feyruz V. Rassool | 2017 | 现代生物医学进展2017，17，11： | 0 |
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