|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Analgesic effect of parecoxib and flurbiprofen axetil for patients undergoing laparoscopic cholecystectomy and their influences on platelet aggregation显示文摘当它能也引起时, opioids 生产手术后的痛觉缺失,这被知道当它能也引起时,副作用喜欢恶心,呕吐,便秘,中略,发痒的皮肤,尿保留和因素都有的甚至呼吸的 inhibition.These 极大地为治疗手术后的疼痛限制了它的临床的使用。同时, non-steroidal 反煽动性拖(NSAID ) 在手术后的痛觉缺失起一个日益重要的作用。一些研究建议 NSAIDS 可能是神经的在服的 ischemic conditions.1 Flurbiprofen 保护 axetil,它利用类脂化合物 microsphere 拖交货系统,可以由煽动性的房间支持在煽动性的损害地点和吸收小粒的 flurbiprofen 的累积,有效地帮助到的 2 个两因素指向治疗。 Parecoxib 是为静脉内的注射可得到的第一个选择 cyclooxygenase-2 ( COX-2 )禁止者,它对产生 NSAIDs3 的病人有益,对胃肠的骚乱敏感的那些喜欢穿孔,溃疡,并且 bleeding.4 这调查为经历血小板聚集上的 laparoscopic 胆囊炎和他们的影响以便为诊所实践提供某指导的病人估计 parecoxib 和 flurbiprofen axetil 的止痛效果。 | JI Fu-hai JIN Xin YANG Jian-ping ZAN Li-li | 2010 | Chinese Medical Journal2010，，12： | 29 |
| 2 | Strata movement controlling effect of waste and fly ash backfillings in fully mechanized coal mining with backfilling face显示文摘A fully mechanized coal mining with backfilling (FMCMB) provides advantages of safety and efficiency for coal mining under buildings, railways, and water bodies. According to the field geological conditions, we analyzed the controlling effect of strata movement by the waste and fly ash backfilling in FMCMB face. Based on the key strata theory, we established the equivalent mining thickness model, and analyzed the action of the bulk factor of backfilling body to the equivalent mining thickness. In addition, we numerically simulated the controlling function of the strata movement by backfilling bodies with differ- ent strength. And the numerical simulation result show that the deformation of stratum and the subsi- dence of surface can be controlled by FMCMB. The result provides references to the effective execution of fully mechanized coal mining with solid waste backfilling in goaf. | Zhang Jixiong Zhang Qiang Huang Yanli Liu Jinwei Zhou Nan Zan Dongfeng | 2011 | Mining Science and Technology2011，21，5： | 27 |
| 3 | GSDMB promotes non-canonical pyroptosis by enhancing caspase-4 activity显示文摘Gasdermin B (GSDMB) has been reported to be associated with immune diseases in humans, but the detailed molecular mechanisms remain unsolved. The N-terminus of GSDMB by itself, unlike other gasdermin family proteins, does not induce cell death. Here, we show that GSDMB is highly expressed in the leukocytes of septic shock patients, which is associated with increased release of the gasdermin D (GSDMD) N-terminus. GSDMB expression and the accumulation of the N-terminal fragment of GSDMD are induced by the activation of the non-canonical pyroptosis pathway in a human monocyte cell line. The downregulation of GSDMB alleviates the cleavage of GSDMD and cell death. Consistently, the overexpression of GSDMB promotes GSDMD cleavage, accompanied by increased LDH release. We further found that GSDMB promotes caspase-4 activity, which is required for the cleavage of GSDMD in non-canonical pyroptosis, by directly binding to the CARD domain of caspase-4. Our study reveals a GSDMB-mediated novel regulatory mechanism for non-canonical pyroptosis and suggests a potential new strategy for the treatment of inflammatory diseases. | Qin Chen Peiliang Shi Yufang Wang Dayuan Zou Xiuwen Wu Dingyu Wang Qiongyuan Hu Yujie Zou Zan Huang Jianan Ren Zhaoyu Lin Xiang Gao | 2019 | Journal of Molecular Cell Biology2019，11，6： | 22 |
| 4 | Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation显示文摘Disrupted mitochondrial membrane potential (MMP) and reactive oxygen species (ROS) generation are often associated with macrophage pyroptosis. It remains unclear how these forms of mitochondrial dysfunction relate to inflammasome activation and gasdermin-D (Gsdmd) cleavage, two central steps of the pyroptotic process. Here, we also found MMP collapse and ROS generation induced by Nlrp3 inflammasome activation as previous studies reported. The elimination of ROS alleviated the cleavage of Gsdmd, suggesting that Gsdmd cleavage occurs downstream of ROS release. Consistent with this result, hydrogen peroxide treatment augmented the cleavage of Gsdmd by caspase-1. Indeed, four amino acid residues of Gsdmd were oxidized under oxidative stress in macrophages. The efficiency of Gsdmd cleavage by inflammatory caspase-1 was dramatically reduced when oxidative modification was blocked by mutation of these amino acid residues. These results demonstrate that Gsdmd oxidation serves as a de novo mechanism by which mitochondrial ROS promote Nlrp3 inflammasome-dependent pyroptotic cell death. | Yufang Wang Peiliang Shi Qin Chen Zan Huang Dayuan Zou Jingzi Zhang Xiang Gao Zhaoyu Lin | 2019 | Journal of Molecular Cell Biology2019，11，12： | 23 |
| 5 | Fabry disease with acute cerebral infarction onset in a young patient显示文摘To the Editor:Fabry disease (FD)is a recessive X-linked hereditary disease.The onset age of the disease is in children and adolescents mostly.The average time from the onset of symptoms to the definite diagnosis needs 13.7 years in male patients and 16.3 years in female patients.FD happens rarely and it is easy to cause diagnosis and treatment delay.Here,we report a case of FD in a 27-year-old man who developed clinical symptoms with acute cerebral infarction onset to improve doctors' understanding of FD. | Ya-Nan Zhang Zhen-Ni Guo Hong-Wei Zhou Ying-Ying Cheng Jia-Chun Feng Zan Wang | 2019 | Chinese Medical Journal2019，，4： | 21 |
| 6 | The improved element-free Galerkin method for three-dimensional transient heat conduction problems显示文摘With the improved moving least-squares (IMLS) approximation, an orthogonal function system with a weight function is used as the basis function. The combination of the element-free Galerkin (EFG) method and the IMLS approximation leads to the development of the improved element-free Galerkin (IEFG) method. In this paper, the IEFG method is applied to study the partial differential equations that control the heat flow in three-dimensional space. With the IEFG technique, the Galerkin weak form is employed to develop the discretized system equations, and the penalty method is applied to impose the essential boundary conditions. The traditional difference method for two-point boundary value problems is selected for the time discretization. As the transient heat conduction equations and the boundary and initial conditions are time dependent, the scaling parameter, number of nodes and time step length are considered in a convergence study. | ZHANG Zan WANG JianFei CHENG YuMin LIEW Kim Meow | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，8： | 18 |
| 7 | Establishing eutrophication assessment standards for four lake regions, China显示文摘The trophic status assessment of lakes in diferent lake regions may provide important and fundamental information for lake trophic state classification and eutrophication control. In this study, a region-specific lake eutrophication assessment standard was established through a frequency distribution method based on chlorophyll-a concentration. The assessment standards under the oligotrophic state for lakes in the Eastern plain, Yungui Plateau, Northeast Plain and Mountain Mongolia-Xinjiang regions are total phosphorus of 0.068,0.005, 0.011, 0.005 mg/L; total nitrogen of 1.00, 0.16, 0.37, 0.60 mg/L; Secchi depth of 0.60, 8.00, 1.55, 3.00 m; and CODMn of2.24, 1.00, 5.11, 4.00 mg/L, respectively. Moreover, a region-specific comprehensive trophic level index was developed to provide an understandable assessment method for the public. The results indicated that the frequency distribution analysis based on chlorophyll-a combined with trophic level index provided a useful metric for the assessment of the lake trophic status. In addition, the diference of eutrophication assessment standards in diferent lake regions was analyzed, which suggested that the sensitivities of algae to nutrients and the assessment standard of trophic status possessed significant regional diferences for the four lake ecoregions. Lake eutrophication assessment standards would contribute to maximizing the efectiveness of future management strategies, to control and minimize lake eutrophication problems. | Shouliang Huo Chunzi Ma Beidou Xi Jing Su Fengyu Zan Danfeng Ji Zhuoshi He | 2013 | Journal of Environmental Sciences2013，25，10： | 18 |
| 8 | Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats显示文摘在糖尿病的可勃起的机能障碍(编辑) 的高发生为有效处理策略加亮需要。Resveratrol,沉默信息管理者 2-related 酶的使活跃之物 1 (sirtuin1, SIRT1 ) ,在癌症, neurodegenerative 疾病,长寿和心血管的疾病为它的珍贵效果收到了注意。在导致糖尿病的编辑探索 resveratrol 的效果, resveratrol 与 streptozocin 予老鼠被以(65 mg kg −1)-induced 糖尿病。可勃起的功能,多孔的结构,沉默信息管理者 2-related 酶的织物蛋白质表示 1 (sirtuin1, SIRT1 ) , p53 和 O 3a (FOXO3a )(MDA ) , superoxide dismutase (草皮) 活动和 malondialdehyde 在阴茎海绵体铺平的 forkhead 抄写因素被学习。我们发现 SIRT1 在 cavernosal 组织被表示,并且它是在糖尿病的老鼠的宫体的 downregulated。resveratrol upregulated 的管理 SIRT1 和恢复可勃起的功能的表示。相反, resveratrol downregulated p53 和 FOXO3a 的表示,调整 apoptosis 和氧化应力。而且,对待 resveratrol 的组在光滑的肌肉内容,草皮活动和 MDA 层次看了改进什么时候与糖尿病患者相比组织。因此, resveratrol 的能力改进导致糖尿病的编辑与它 SIRT1 表示的激活有关是可能的,因此向氧化应力引起 apoptosis 和抵抗的抑制。 | Wen Yu Zan Wan Xue-Feng Qiu Yun Chen Yu-Tian Dai | 2013 | Asian Journal of Andrology2013，15，5： | 15 |
| 9 | Effect of Poria cocos Hydroethanolic Extract on Treating Adriamycin-Induced Rat Model of Nephrotic Syndrome显示文摘Objective: To evaluate the effect of Poria cocos(Schw.) Wolf hydroethanolic extract(PHE) against nephrotic syndrome(NS) in rats and to identify the potential active components from PHE. Methods: The high content compounds were isolated and purified by using column chromatography followed by preparative highperformance liquid chromatography(p-HPLC). Forty male Wistar rats with adriamycin(ADR)-induced NS were randomly divided into 5 groups, 8 in each group: model control group, positive control group(with prednisone treatment), PHE low-dose group, PHE middle-dose group and PHE high-dose group. Another 8 rats were recruited as vehicle control group. All rats received the intragastric administration of corresponding drugs or saline for 30 days. During the experimental period, rats' behavior and appearance were observed and recorded daily, and their body weights were recorded weekly. After treatment, 24-h urine samples were collected to evaluate the urine protein and urine creatinine(Ucr); then the rats were sacrificed to collect carotid blood and to determine the levels of serum total protein(TP), albumin(Alb), globulin(Glo), total cholesterol(TC) and cytokine interlukin-4(IL-4). Results: Six acidic components were isolated and identified from the PHE section: pachymic acid, 15α-hydroxydehydrotumulosic acid, trametenolic acid, dehydropachymic acid, 3β-hydroxy-lanosta-7,9(11), 24-trien-21-oic-acid and dehydroeburicoic acid. Compared with the model control group, the urine protein content were significantly decreased in the PHE treatment groups and positive control group(P<0.05), especially PHE middle-dose group(P<0.01). The Ucr values and serum levels of TP, Glo, TC and IL-4 in PHE low-and middle-dose groups were also presented obvious recover tendency as compared with the model control group(P<0.05 or P<0.01). However, positive control group and all PHE groups indicated no significant therapeutic effect on raising Alb value, although PHE low-and middle-dose treatment groups showed better outcomes than positive control group(P>0.05). Conclusions: PHE showed an encouraging therapeutic effect against ADR-induced NS in a rat model. PHE might be a group of effective substances for the treatment of NS. | ZAN Jun-feng SHEN Chan-juan ZHANG Li-ping LIU Yan-wen | 2017 | Chinese Journal of Integrative Medicine2017，23，12： | 15 |
| 10 | Using the Prostate Imaging Reporting and Data System version 2 (PI-RIDS v2) to detect prostate cancer can prevent unnecessary biopsies and invasive treatment显示文摘 | Chang Liu Shi-Liang Liu Zhi-Xian Wang Kai Yu Chun-Xiang Feng Zan Ke Liang Wang Xiao-Yong Zeng | 2018 | Asian Journal of Andrology2018，20，5： | 13 |
| 11 | Bufalin suppresses the migration and invasion of prostate cancer cells through HOTAIR, the sponge of miR-520b显示文摘Bufalin, the major active component of the traditional Chinese medicine ChanSu obtained from the skin and parotid venom glands of toads, has long been known as an anticancer agent. Recent studies show that microRNAs (miRs) are involved in the anticancer activities of bufalin, while long non-coding RNAs (lncRNAs) are known to interact with miRNAs to regulate various biological functions. In this paper, we investigated the possible network related to the antimetastatic effect of bufalin in prostate cancer (PCa) cells. We demonstrated that bufalin (0.05?10 μM) dose-dependently suppressed the proliferation of prostate cancer DU145 and PC3 cells with IC50 values of 0.89 and 1.28 μM, respectively. Furthermore, bufalin treatment significantly suppressed the cell migration and invasion. To explore the role of lncRNAs in the antimetastatic activity of bufalin, we used an lncRNA microarray and found that HOX transcript antisense RNA (HOTAIR) was the most markedly downregulated lncRNA in bufalin-treated PCa cells. Overexpression of HOTAIR counteracted the suppressing effects of bufalin on DU145 and PC3 cells. We then predicted and verified that HOTAIR upregulated FGFR1 expression by sponging miR-520b in PCa cells. In 40 patients with PCa bone metastasis, we used in situ hybridization or immunohistochemical assay to assess the HOTAIR and FGFR1 expression, which revealed that both HOTAIR and FGFR1 expression were significantly higher in bone metastasis tissues than in the primary PCa tissues. In addition, the level of serum HOTAIR was positively associated with the levels of serum bone metabolic markers (CTx, OST, B-ALP and PINP) and may serve as a reasonable biomarker for PCa bone metastasis. Taken together, this is the first study revealing that HOTAIR promotes PCa bone metastasis, and bufalin may be a promising candidate for the treatment of this disease. | Jian-jun Zhang Xiao-hui Zhou Yan Zhou Yong-gang Wang Bin-zhi Qian Ai-na He Zan Shen Hai-yan Hu Yang Yao | 2019 | Acta Pharmacologica Sinica2019，40，9： | 13 |
| 12 | The improved element-free Galerkin method forthree-dimensional wave equation显示文摘The paper presents the improved element-freeGalerkin(IEFG) method for three-dimensional wave propagation.The improved moving least-squares(IMLS) approximation is employed to construct the shape function,whichuses an orthogonal function system with a weight function asthe basis function.Compared with the conventional movingleast-squares(MLS) approximation,the algebraic equationsystem in the IMLS approximation is not ill-conditioned,andcan be solved directly without deriving the inverse matrix.Because there are fewer coefficients in the IMLS than in theMLS approximation,fewer nodes are selected in the IEFGmethod than in the element-free Galerkin method.Thus,theIEFG method has a higher computing speed.In the IEFGmethod,the Galerkin weak form is employed to obtain a discretized system equation,and the penalty method is appliedto impose the essential boundary condition.The traditionaldifference method for two-point boundary value problems isselected for the time discretization.As the wave equationsand the boundary-initial conditions depend on time,the scaling parameter,number of nodes and the time step length areconsidered for the convergence study. | Zan Zhang Dong-Ming Li Yu-Min Cheng Kim Moew Liew | 2012 | Acta Mechanica Sinica2012，28，3： | 12 |
| 13 | Associations between individual and environmental factors and habitual physical activity among older Chinese adults:A social–ecological perspective显示文摘Purpose: To examine, within a social–ecological framework, associations between multifaceted individual and environmental factors and habitual physical activity(HPA) among older Chinese adults.Methods: Through a mix of qualitative and quantitative methods, a survey instrument assessing various factors underlying 3 social–ecological dimensions of intrapersonal, interpersonal, and community and environmental resources was developed. Using a cross-sectional design, older adults(n = 1580, aged 67 ± 7 years) recruited from 10 communities in Shandong province completed the social–ecological survey of HPA. Data were analyzed using Partial Least Squares Path Modeling.Results: Factors related to intrapersonal(medical knowledge, motivation, physical function, sport skills, socioeconomic status, and education),interpersonal(social support, social activity, and social norms), and community and physical environmental resources(safety, capacity, availability of and access to physical activity facilities) were found to be significantly associated with older adults' participation in HPA.Conclusion: The findings provide an initial validation of a social–ecological approach to the study of HPA in China, suggesting that strategies aimed at promoting physical activity in older adults should address multiple levels of factors that may contribute to the likelihood of older Chinese adults being physically active. | Xiangren Yi Zachary Pope Zan Gao Shumei Wang Fang Pan Jingpeng Yan Meng Liu Peipei Wu Jingjing Xu Rui Wang | 2016 | Journal of Sport and Health Science2016，5，3： | 11 |
| 14 | Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer显示文摘Ferroptosis is a type of cell death accompanied by iron-dependent lipid peroxidation,thus stimulating ferroptosis may be a potential strategy for treating gastric cancer,therapeutic agents against which are urgently required.Jiyuan oridonin A(JDA) is a natural compound isolated from Jiyuan Rabdosia rubescens with anti-tumor activity,unclear anti-tumor mechanisms and limited water solubility hamper its clinical application.Here,we showed a2,a new JDA derivative,inhibited the growth of gastric cancer cells.Subsequently,we discovered for the first time that a2 induced ferroptosis.Importantly,compound a2 decreased GPX4 expression and overexpressing GPX4 antagonized the anti-proliferative activity of a2.Furthermore,we demonstrated that a2 caused ferrous iron accumulation through the autophagy pathway,prevention of which rescued a2 induced ferrous iron elevation and cell growth inhibition.Moreover,a2 exhibited more potent anti-cancer activity than 5-fluorouracil in gastric canc er cell line-derived xenograft mice models.Patient-derived tumor xenograft models from different patients displayed varied sensitivity to a2,and GPX4 downregulation indicated the sensitivity of tumors to a2.Finally,a2 exhibited well pharmacokinetic characteristic s.Overall,our data suggest that inducing ferroptosis is the major mechanism mediating anti-tumor activity of a2,and a2 will hopefully serve as a promising compound for gastric cancer treatment. | Ying Liu Zan Song Yajie Liu Xubin Ma Wang Wang Yu Ke Yichao Xu Dequan Yu Hongmin Liu | 2021 | Acta Pharmaceutica Sinica B2021，11，6： | 10 |
| 15 | Effects of exergaming on motor skill competence,perceived competence,and physical activity in preschool children显示文摘Background: Few school settings offer opportunities for preschool children to engage in structured physical activity, and only a few studies have been conducted examining exergaming's effectiveness on health outcomes in this age group. This study's purpose, therefore, was to examine a school-based exergaming intervention's effect on preschool children's perceived competence(PC), motor skill competence(MSC), and physical activity versus usual care(recess), as well as to examine gender differences for these outcomes.Methods: A total of 65 preschool children from 2 underserved urban schools were assigned to 1 of 2 conditions, with the school as the experimental unit:(1) usual care recess group(8 weeks of 100 min of recess/week(5 days ￡ 20 min)) and(2) exergaming intervention group(8 weeks of100 min of exergaming/week(5 days ￡ 20 min) at school). All children underwent identical assessments of PC, MSC, and moderate-to-vigorous physical activity(MVPA) at baseline and at the end of the 8 th week.Results: A significant Group ￡ Time effect was observed for MVPA, F(1, 52) = 4.37, p = 0.04, h2 p= 0.04, but not for PC, F(1, 52) = 0.83, p = 0.37,h2 p= 0.02, or MSC, F(1, 52) = 0.02, p = 0.88, h2 p= 0.00. Specifically, the intervention children displayed significantly greater increased MVPA after8 weeks than the comparison children. Additionally, there was a significant time effect for MSC, F(1, 52) = 15.61, p < 0.01, h2 p= 0.23, and gender effect for MVPA, F(1, 52) = 5.06, p = 0.02, h2 p= 0.09. Although all preschoolers' MSC improved across time, boys demonstrated greater MVPA than girls at both time points.Conclusion: Exergaming showed a positive effect in promoting preschool children's MVPA at school and has the potential to enhance PC and MSC. More research with larger sample sizes and longer study durations are warranted. | Zan Gao Nan Zeng Zachary C.Pope Ru Wang Fang Yu | 2019 | Journal of Sport and Health Science2019，8，2： | 10 |
| 16 | Key genes expressed in different stages of spinal cord ischemia/reperfusion injury ischemia/reperfusion injury显示文摘The temporal expression of microRNA after spinal cord ischemia/reperfusion injury is not yet fully understood.In the present study,we established a model of spinal cord ischemia in Sprague-Dawley rats by clamping the abdominal aorta for 90 minutes,before allowing reperfusion for 24 or 48 hours.A sham-operated group underwent surgery but the aorta was not clamped.The damaged spinal cord was removed for hematoxylin-eosin staining and RNA extraction.Neuronal degeneration and tissue edema were the most severe in the 24-hour reperfusion group,and milder in the 48-hour reperfusion group.RNA amplification,labeling,and hybridization were used to obtain the microRNA expression profiles of each group.Bioinformatics analysis confirmed four differentially expressed microRNAs(miR-22-3p,miR-743b-3p,miR-201-5p and miR-144-5p) and their common target genes(Tmem69 and CxcllO).Compared with the sham group,miR-22-3p was continuously upregulated in all three ischemia groups but was highest in the group with no reperfusion,whereas miR-743b-3p,miR-201-5p and miR-144-5p were downregulated in the three ischemia groups.We have successfully identified the key genes expressed at different stages of spinal cord ischemia/reperfusion injury,which provide a reference for future investigations into the mechanism of spinal cord injury. | lian-an Li Chun-fang Zan Peng Xia Chang-jun Zheng Zhi-ping Qi Chun-xu Li Zhi-gang Liu Ting-ting Hou Xiao-yu Yang | 2016 | Neural Regeneration Research2016，11，11： | 9 |
| 17 | The effects of a bike active video game on players' physical activity and motivation显示文摘Background: Players may not acquire adequate levels of moderate-to-vigorous physical activity(MVPA) when playing commercial video games.This study's goal was to evaluate the effects of an exercise bike video game played by using a mobile application-based exergame that was designed exclusively to promote participants' MVPA, with additional attention paid to this game's ability to promote greater situational interest.Methods: An experimental design was used with 163 students(aged 20.31 ± 1.30, 18–26 years, 61.3% male), all of whom were randomly allocated into an experimental group and a control group. Physical activity(PA) levels were assessed with Acti Graph GT3X+(Acti Graph Inc., Fort Walton Beach, FL, USA) accelerometers. The situational interest scale was used to evaluate students' situational interest in both groups.Multivariate analysis of variance was conducted to examine the differences between sedentary behavior, PA levels, and situational interest between groups. Regression analyses were also used, with the purpose being to evaluate the strength of the relationship between PA and situational interest.Results: Results revealed that the experimental group had higher degrees of sedentary behavior, light PA, total interest, instant enjoyment,exploration intention, attention demand, novelty, and challenge, whereas the control group received higher scores for MVPA(control 95.01% vs.experimental group 89.94%). Regression analysis indicated that instant enjoyment(β = 0.49, p < 0.01), exploration intention(β = 0.18, p < 0.05),and attention demand(β = 0.17, p < 0.05) were positive predictors for total interest, explaining 43% of its variance.Conclusion: A newly designed mobile application-based exergame played via an exercise bike may enhance situational interest and provide a decent level of PA for players. | Denis Pasco Cédric Roure Gilles Kermarrec Zachary Pope Zan Gao | 2017 | Journal of Sport and Health Science2017，6，1： | 9 |
| 18 | Effects of Age on Quality of Beef from Qinchuan Cattle Carcass显示文摘Qinchuan cattle are one of the top breeds in China.In the current study,cattle of different ages were used to investigate the effect of age on beef quality.With increasing age,shear force,protein content,hydroxyproline(Hyp) content,redness(a*),and muscle fiber diameter and density significantly increased(P<0.05).On the other hand,cooking loss,water content,lightness(L*),and muscle fiber gap markedly decreased(P<0.05).No significant differences were found in the contents of intramuscular fat,ash,amino acids(AA),mineral elements,and expression level of leptin and FAS(P>0.05).The C16:0 and C18:0 content increased significantly(P<0.05),in contrast to that of C18:1 and C18:2(P<0.05).COLA1 mRNA was expressed at low levels at mon 3 and 9 but markedly increased at mon 12 and 15(P<0.05).Taken together,these observations demonstrate excellent nutritional values of beef from cattle of different ages concordant with their chemical properties;on the other hand,their commercial value correlates more closely with their physical and sensory characteristics. | LI Lin-qiang TIAN Wan-qiang ZAN Lin-sen | 2011 | Agricultural Sciences in China2011，10，11： | 9 |
| 19 | Pirarubicin inhibits multidrug-resistant osteosarcoma cell proliferation through induction of G~/M phase cell cycle arrest显示文摘 | Shui-er ZHENG Sang XIONG Feng LIN Guang-lei QIAO Tao FENG Zan SHEN Da-liu MIN Chun-ling ZHANG Yang YAO | 2012 | Acta Pharmacologica Sinica2012，33，6： | 9 |
| 20 | Potato/Maize intercropping reduces infestation of potato tuber moth, Phthorimaea operculella(Zeller) by the enhancement of natural enemies显示文摘The potato tuber moth(PTM),Phthorimaea operculella(Zeller),is one of the most economically significant insect pests for potato in both field and storage worldwide.To evaluate the infestation,reduction of potato yield and the control efficacy for PTM,field tests were conducted in two seasons by intercropping of potato as the host plant with maize as a non-host plant of PTM.Three intercropping patterns were tested,which were 2 rows of potatoes with either 2,3,or 4 rows of maize(abbreviated 2 P:2 M,2 P:3 M,and 2 P:4 M),and the monocropped potato as the control,2 rows of potatoes,without maize,(abbreviated 2 P:0 M).Results showed that the population and infestation of PTM in the 2 P:3 M intercropping pattern was significantly lower than those in 2 P:2 M,2 P:4 M and the monocropping pattern of 2 P:0 M,due to the enhancement of natural enemies.Cumulative mines and tunneling in potato leaves in 2 P:3 M intercropping were significantly lower than those in 2 P:2 M and 2 P:4 M patterns.The population of parasitoids and the parasitism rate of PTM in intercropping pattern of 2 P:3 M were significantly higher than that in intercropping pattern of 2 P:2 M,2 P:4 M and monocropping pattern of 2 P:0 M.We conclude that the potato intercropped with maize reduced the adult and larva populations,and reduced the damage from PTM by enhancing the number of parasitoids and the level of parasitism.The greatest population density of parasitoids and parasitism rate were in the intercropping pattern of 2 rows of potatoes with 3 rows of maize.These data indicate that the host/non-host intercropping patterns can be used as a biological control tactic against PTM by enhancing the density of natural enemies in the agro-ecosystems. | ZHENG Ya-qiang ZHANG Li-min CHEN Bin YAN Nai-sheng GUI Fu-rong ZAN Qing-an DU Guang-zu HE Shu-qi LI Zheng-yue GAO Yu-lin XIAO Guan-li | 2020 | Journal of Integrative Agriculture2020，19，2： | 8 |
您所在的机构暂未开通此部分的功能，请联系管理员