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| 1 | Prognostic criteria for postoperative mortality in 170 patients undergoing major right hepatectomy显示文摘BACKGROUND: Postoperative hepatic failure is a dreadful complication after major hepatectomy and carries high morbidity and mortality rates. In this study, we assessed the accuracy of the 50/50 criteria (bilirubin >2.9 mg/dL and international normalized ratio >1.7 on postoperative day 5) and the Mullen criteria (bilirubin peak >7 mg/dL on postoperative days 1-7) in predicting death from hepatic failure in patients undergoing right hepatectomy only. In addition, we identified prognostic factors linked to intra-hospital morbidity and mortality in these patients. METHODS: One hundred seventy consecutive patients underwent major right hepatectomy at a tertiary medical center from 2000 to 2008. Nineteen (11.2%) patients suffered from liver cirrhosis. Univariate and multivariate analyses were performed to identify predictors of intra-hospital mortality, morbidity and death from hepatic failure. RESULTS: The intra-hospital mortality was 6.5% (11/170). Of the six patients who died from hepatic failure, one was positive for the 50/50 criteria, but all six patients were positive for the Mullen criteria. Multivariate analysis showed that male gender, hepatitis C (HCV), hepatocellular carcinoma, postoperative bilirubin >7 mg/dL and ALT<188 U/L on postoperative day 1 were predictive of death from hepatic failure in the postoperative period. Age >65 years, HCV, reoperation, andrenal failure were significant predictors of overall intra-hospital mortality on multivariate analysis. CONCLUSIONS: The Mullen criteria were more accurate than the 50/50 criteria in predicting death from hepatic failure in patients undergoing right hepatectomy. A bilirubin peak >7 mg/dL in the postoperative period, HCV positivity, hepatocellular carcinoma, and an ALT level <188 U/L on postoperative day 1 were associated with death from hepatic failure in our patient population. | Filippo Filicori Xavier M Keutgen Matteo Zanello Giorgio Ercolani Salomone Di Saverio Federico Sacchetti Antonio Daniele Pinna Gian Luca Grazi | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，5： | 2 |
| 2 | Improved diagnostic imaging and interventional therapies prolong survival after resection for hepatocellular carcinoma in cirrhosis:the university of bologna experience over 10 years显示文摘 | Cucchetti A Zanello M Cescon M | 2011 | Ann Surg Oncol2011，18，6： | 1 |
| 3 | Saccharomyees boulardii effects on gastrointestinal diseases显示文摘 | Zanello G Meurens F Berri M | 2009 | Curr Issues Mol Biol2009，11，1： | 1 |
| 4 | Saccharomyces boulardii effects on gastrointestinal disease显示文摘 | ZANELLO G MEURENS F BERRI M | 2009 | Current Issues in Molecular Biology2009，11，1： | 1 |
| 5 | Activity of GH/IGF-I axis in trauma and septic patients during artificial nutrition:different behavior patterns?显示文摘 | Pittoni G Gallioi G Zanello M | 2002 | J Endocrinol Invest2002，25，3： | 1 |
| 6 | Changes in the surgical approach to hilar cholangiocarcino-ma during an 18-year period in a Western single center显示文摘 | Ercolani G Zanello M Grazi GL | 2010 | J Hepatobilia- ry Pancreat Sci2010，17，3： | 1 |
| 7 | Saccharomyces boulardii effects on gastrointestinal diseases显示文摘 | Zanello G Meurens F Berri M Salmon H | 2009 | Curr Issues Mol Biol2009，11，1： | 1 |
| 8 | Saccharomyces boulardiieffects on gastrointestinal diseases显示文摘 | Zanello G Meurens F Berri M Salmon H | 2009 | Curr Issues Mol Biol2009，11，1： | 1 |
| 9 | U sing elderly donors in liver transplan tat ion显示文摘 | Grazi G L Ravaloli M Zanello M | 2005 | TransplantProc2005，，37： | 1 |
| 10 | Activity of GH/IGF - 1 axis in trauma and septic patients during artificial nutrition: different behavior patterns?显示文摘 | pittani G Gallioi G Zanello M | 2002 | J Endocrinol Invest2002，25，3： | 1 |
| 11 | Saccharomyces cerevisiae modulates immune gene expressions and inhibits ETEC-mediated ERK1/2 and p38 signaling pathways in intestinal epithelial cells显示文摘 | Zanello G Berri M Dupont J | | 0，，04： | 1 |
| 12 | Changes in the surgical approach to hilar chol-angiocarcinoma during an 18-year period in a western single center显示文摘 | ERCOLANI G ZANELLO M GRAZI G L | 2010 | J Hepatobiliary Pancreat Sci2010，17，： | 1 |
| 13 | Diffusion-weighted imaging (DWI) of adenomyosis and /'ibroids of the uterus显示文摘 | Jha R C Zanello P A Ascher S M et aI | 2014 | Abdom Imaging2014，39，3： | 1 |
| 14 | Changes in the surgical approach to hilar cholangiocarcinoma during an 18-year period in a Western single center显示文摘 | Ercolani G Zanello M Gian LG | 2010 | J Hepatobiliary Pancreat Sci2010，17，3： | 1 |
| 15 | Changes in the surgical ap-proach to hilar cholangiocarcinoma during an 18 - year period in aWestern single center显示文摘 | Ercolani G Zanello M Grazi GL | 2010 | J Hepatobiliary Pancreat Sci2010，17，3： | 1 |
| 16 | On the mechanism of the antitumor activity of ferrocenium derivatives显示文摘 | Osella D Ferrali M Zanello P | 2000 | Inorg Chim Acta2000，306，： | 1 |
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