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1Evaluation of extracts and essential oil from Callistemon viminalis leaves:Antibacterial and antioxidant activities,total phenolic and flavonoid contents显示文摘Objective:To investigate antioxidant and antibacterial activities of Callistemon viminalis(C.viminalis)leaves.Methods:The essential oil of C.viminalis leaves obtained by hydrodistillation was analyzed by GC/MS.Different extracts were tested for total phenolic and flavonoid contents and in vitro antioxidant(DPPH assay)and antibacterial(agar disc diffusion and 96-well micro-plates methods)actives.Results:Fourteen components were identified in the essential oil,representing 98.94%of the total oil.The major components were 1,8-cineole(64.53%)andα-pinene(9.69%).Leaf essential oil exhibited the highest antioxidant activity of(88.60±1.51)%comparable to gallic acid,a standard compound[(80.00±2.12)%].Additionally,the biggest zone of inhibitions against the studied bacterial strains was observed by the essential oil when compared to the standard antibiotic(tetracycline).The crude methanol extract and ethyl acetate fraction had a significant antibacterial activity against the tested bacterial strains.Conclusions:It can be suggested that C.viminalis is a great potential source of antibacterial and antioxidant compounds useful for new antimicrobial drugs from the natural basis.The present study revealed that the essential oil as well as the methanol extracts and ethyl acetate fraction of C.viminalis leaves exhibited highly significant antibacterial activity against the tested bacterial strains.Mohamed ZM Salem Hayssam M Ali Nader A El-Shanhorey Ahmed Abdel-Megeed 2013Asian Pacific Journal of Tropical Medicine2013,6,10:14
2何首乌中一个新的吲哚衍生物显示文摘杨季伟 Gu.,ZM 1998中草药1998,29,1:13
3DSA analysis of hepatic arteriovenous fistula concurrent with hepatic cancer and its clinical significance显示文摘INTRODUCTIONIntervention therapy has become one of the maintherapies of hepatic cancer.Theintroduction of hepatic arterial perfusion andembolization has provided opportunities for asecondary operation on patients with intermediateand advanced cancer,thusGuo WP Zhang HX Wang ZM Wang YQ Ni DH Li WX Guan Y 2000World Journal of Gastroenterology2000,6,6:11
4Survival factors after resection of small hepatocellular carcinoma显示文摘Early resection of hepatocellular carcinoma is a key measure to prolong the survival of patients. This study was designed to summarize our experience in surgical resection of small hepatocellular carcinoma (HCC), and to analyze the factors influencing the postoperative survival of patients. METHODS:The clinicopathologic data of 105 patients with small HCC after resection from 1986 through 2003 were analyzed ; the patients had been followed up for more than half a year (median 33 months). Nine clinicopathologic factors, preoperative α-fetoprotein (AFP) level, liver cirrhosis, Child-Pugh score, tumor size (>2cm vs.≤2 cm) and number (single vs. multiple), capsule formation, portal vein tumor thrombi (PVTT), Edmondson tumor grade and surgical method, were analyzed by the log-rank test and the Cox proportional harzards model analysis. RESULTS:The cumulative 1-,3- and 5-year survival rates after the operation were 86.5%, 70.3% and 55.2%, respectively, and the 1-, 3- and 5-year disease-free survival rates were 78%, 58. 9% and 45. 6%, respectively. One patient died from esophagogastric varices hemorrhage in 2 weeks after reoperation. Thirty-six patients had intrahepatic recurrence or metastasis postoperatively and 34 patients died. The Kaplan-Meier method and the Cox proportional harzards model analysis indicated that poor Child-Pugh score, tumor more than 2 cm in diameter, PVTT and multiple lesions (including satellitic lesions) were adverse factors affecting postoperative survival. The Cox proportional harzards model analysis indicated that tumor size, PVTT and multiple lesions were the factors influencing postoperative disease-free survival. CONCLUSIONS:Limited hepatectomy with a margin more than 1 cm is an appropriate surgical approach. Adverse preoperative Child-Pugh score and postoperative intrahepatic recurrences are the main factors leading to the death of patients with small HCC.Departments of Surgical Oncology (Wu FS, Zhao WH, Ma ZM, Teng LS and Wang M) and General Surgery ( Liang TB and Zheng SS) , First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China 2005Hepatobiliary & Pancreatic Diseases International2005,4,3:5
5Black and green tea consumption and the risk of coronary artery disease, a meta-analysis显示文摘Wang ZM Zhou, B Wang, YS Gong, QY Wang, QM Yan, JJ Gao, W Wang, LS 2011南京医科大学学报(自然科学版)2011,31,4:5
6Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor显示文摘AIM To determine the activities ofpolysaccharide extracts from Flammulina velutipes (Curt. ex Fr. ) Sing (FV), Lentinusedodes (LE) and Agaricus bisporus Sing (AB)on the proliferation of human hepatoma SMMC-7721 cells in vitro and on mouse implanted S-180tumors in vivo.METHODS The polysaccharide extracts were isolated from the fruit bodies of FV, LE and AB by the methods of hot-water extraction, Sevag’sremoval of proteins, ethanol precipitation,trypsin digestion and ethanol fractionalprecipitation. Human hepatoma SMMC-7721 cells were treated with 50 mg/L Polysaccharide extracts, and the mitosis index, mitochondria activity and cell proliferation were detected at different times in both control and experimental groups. The mice with S-180 implanted tumors were injected with the polysaccharide extracts at 24 mg/ kg body weight for 9 d and the tumorweight was measured on the 15th day.RESULTS The mitosis index of hepatoma cells in vitro could be significantly decreased by treatment with the polysaccharide extracts fromthe three kinds of edible fungi (P < 0 .005 ). Thecell numbers and mitochondria activity of SMMC7721 cells treated with polysaccharide extracts were lower than those in control groups (P <0.005). The inhibition rates of polysaccharide extracts against implanted S-180 tumors in mice were 52.8%, 56.6% and 51 .9% respectivelycompared with that in c0ntrol gr0ups.CONCLUSI0N The POIysaccharide extractsfrom the three kinds of edible fungi could inhibitnot only the Cultured malignant cells in vitfO butalso impIanted Sl80 tum0r i0 vivo.Jiang SM Xiao ZM Xu ZH 1999World Journal of Gastroenterology1999,5,5:5
7Radiotherapy of double primary esophageal carcinoma显示文摘INTRODUCTIONDouble primary esophageal carcinoma is defined ashaving two loci of squamous cell cancersimultaneously or consecutively developing indifferent sites of esophagus.This rare diseaseappears mostly in the literature as case reports,reports about its treatment are even moreinfrequent.Here we present our experiencesXiao ZF Yang ZY Zhou ZM Yin WB Gu XZ 2000World Journal of Gastroenterology2000,6,1:4
8Syntax of first-order lattice valued logic system FM显示文摘PAVELKA in ref. [1] established a propositional logic system whose truth values domain is an enriched residuated lattice and obtained some beautiful results. In order to study more general lattice valued logic systems, we proposed the concept of lattice implication algebra, discussed the corresponding lattice valued propositional logic system, and established aXu, Y Qin, KY Song, ZM 1997Chinese Science Bulletin1997,42,16:4
9Cloning of environmental genomic fragments as physical markers for monitoring microbial populations in coking wastewater treatment system显示文摘Yan X Xu ZM Feng XX Liu YD Liu BB Zhang X J Zhu CG Zhao LP 2007中国生物学文摘2007,21,8:4
10Anti-duck hepatitis B virus mechanism by Shui Qin extraction显示文摘THE duck hepatitis B virus as well as the human hepatitis B virus (HBV) belong to the hepadnaviruses. The viral DNA acts as a template for the synthesis, by DNA polymerase (DNAp). This enzyme is a DNA-dependent DNAp. It is a target enzyme of anti-hepatitis drugs too. Based on Shui Qin (SQ) anti-hepatitis B virus we used DHBV DNAp as a model inHuang, ZM Yang, XB Cao, WB 1997Chinese Science Bulletin1997,42,17:3
11Rapid isolation and identification of Mycobacterium tuberculosis from pulmonary tuberculosis patients显示文摘Objective:The Study aimed to develop a rapid inexpensive and simple method for preliminary isolation and detection of M.tuberculosis from clinical specimens.Also to probe the impact of deteriorating health measures on the pulmonary tuberculosis control program in Basra city.Methods:A simple monophasic-diphasic setup (MDCS) was used for the isolation and preliminary identification of M.tuberculosis.This setup consists of a slanted Lowenstein-Jensen medium,the bottom of it is covered with 1 mL of tuberculosis broth thus establishing a diphasic solid liquid environment at the bottom of the screw capped test tube and above them a monophasic one.Results:During 7 months period from the beginning of December 2003 to the end of June 2004,1 295 cases were managed in Tuberculosis and Chest Diseases Clinic in Basra city.Only 348 cases were diagnosed as active pulmonary tuberculosis.They consist of 232 new cases and 116 previously registered ones.The MDCS method showed higher recovery of isolation rate of M.tuberculosis(92.3%) than Lowenstein-Jensen,and pyruvate methods with 78.1%and 51.9%respectively.Also this method revealed more rapid appearance of results of 12 days than Lowenstein-Jensen,and pyruvate media with 22 days and 23 days respectively by the traditional culturing methods.Concurrently the study revealed that drug resistance against one or more anti tuberculosis drugs was 23.1%for new cases and 70.8%for the old ones.Multi drug resistance accounts for 20%of total isolates from old cases.This was based on using the critical concentration and 1%proportional procedures.Tuberculosis was more common among males than females with 69.4%and 30.6%respectively. A significant correlation(P<0.05) was found between the productive age group(25-54) and incidence of tuberculosis. Tuberculosis was higher among married(83.8%) than unmarried peoples(22%).Children,husbands and wives showed higher infection rates than others indicating kinship influence.Failure of treatment was highly affected by improper use of anti tuberculosis drugs.Conclusion:The MDCS method exhibited several advantages over other culturing techniques exemplified by elimination of transport medium,establishment of simultaneous but two separate environments to accomplish both the detection and preliminary identification of M.tuberculosis,providing flexibility in the kinds of media used in the liquid and solid phases and it is inexpensive.Al-Sulami AA Ali ZM Al-Maleky DA 2009Asian Pacific Journal of Tropical Medicine2009,2,3:3
12Intraspinal transplantation of CD34+ human umbilical cord blood cells after spinal cord hemisection injury improves functional recovery in adult rats显示文摘Zhao,ZM Li,HJ Liu,HY Lu,SH Yang,RC Zhang,QJ Han,ZC 2005中国生物学文摘2005,19,3:2
13SELECTIVE DIMERIZATION OF BUTANAL TO BUTYL BUTYRATE CATALYZED BY LANTHANOCENE/n-BuLi SYSTEMS显示文摘SELECTIVEDIMERIZATIONOFBUTANALTOBUTYLBUTYRATECATALYZEDBYLANTHANOCENE/n-BuLiSYSTEMS¥FanXU,LiLuZHANG,MingYAO,YuanChenDING,ZhiMi...Xu, F Zhang, LL Yao, YM Ding, YC Bai, ZM Shen, Q 1995Chinese Chemical Letters1995,6,7:2
14强化降压对高血压患者左心室肥厚的影响显示文摘目前尚不清楚超出推荐值的强化降压是否更能降低高血压患者的左心室肥厚(left ventricular hypertrophy,LVH)发生风险,以及LVH风险降低能否解释强化降压的益处。Soliman等纳入收缩压干预试验(systolic blood pressure intervention,SPRINT)中患有高血压但无糖尿病的8164例受试者(平均年龄67.9岁,女性35.3%,31.2%为非洲裔),刘莉 叶鹏 Soliman EZ Ambrosius WT Cushman WC Zhang ZM Bates JT Neyra JA Carson TY Tamariz L Ghazi L Cho ME Shapiro BP He J Fine LJ Lewis CE SPRINT Research Study Group 2017中华高血压杂志2017,25,6:2
15Investigation on dynamic changes of photosynthetic characteristics of 10 wheat (Triticum aestivum L.) genotypes during two vegetative-growth stages at water deficits显示文摘Shao, HB Liang, ZS Shao, MA Sun, SM Hu, ZM 2006中国生物学文摘2006,20,2:2
16Von Willebrand factor, platelets and endothelial cell interactions显示文摘Ruggeri ZM 2003J Thromb Haemost2003,1,7:1
17Reconstruction of the interosseous ligament unloads metallic radial head arthroplasty and the distal ulna in cadavers 显示文摘Pfaeffle HJ Stabile KJ Li ZM 2006J Hand Surg ( Am)2006,,31:1
18Linearly scaled,rate in variant normal limits for QT interval:eight decades of incorrect application of power functions 显示文摘Rautaharju PM Zhang ZM 2002Cardiovasc Eletrophysiol2002,13,:1
19Targeting Toll-like receptor 9 with CpG oligodeoxynucleotides enhances anti-tumor responses of peripheral blood mononuclear cells from human lung cancer patients 显示文摘Ren T Wen ZK Liu ZM etal 2008Cancer Invest2008,26,5:1
20Clinical features and natural history of nonalcoholic steatosis syndromes显示文摘Falck-Ytter Y Younossi ZM Marchesini G 2001Semin Liver Diseases2001,21,1:1
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