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| 1 | Type 2 diabetes mellitus and CA 19-9 levels显示文摘AIM:To prospectively investigate serum CA 19-9 levels in type 2 diabetic patients in comparison with age-and gender-matched control subjects. METHODS:We recorded duration of diabetes and examined fasting glucose levels,HbA1c levels and serum CA 19-9 levels in 76 type 2 diabetic patients and 76 controls.Abdominal CT was performed in order to eliminate abdominal malignancy in the diabetic and control groups. RESULTS:The average CA 19-9 level was 46.0±22.4 U/mL for diabetic patients whereas it was 9.97±7.1 U/mL for the control group(P<0.001).Regression analysis showed a positive correlation between diabetes and CA 19-9 independent from age,gender,glucose level and HbA1c level(t=8.8,P<001).Two of the diabetic patients were excluded from the study because of abdominal malignancy shown by CT at the initial evaluation.For all patients,abdominal CT showed no pancreatic abnormalities. CONCLUSION:CA 19-9 is a tumor-associated antigen, which is elevated in pancreatic,upper gastrointestinal tract,ovarian hepatocellular,and colorectal cancers,as well as in inflammatory conditions of the hepatobiliary system,biliary obstruction and in thyroid diseases. Diabetes has been claimed to be a risk factor for pancreatic cancer,which is increasing its incidence and has one of the lowest survival rates of all cancers.CA 19-9 is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes.We propose that a higher cut- off value of CA 19-9 should be used in diabetics to differentiate benign and malignant pancreatic disease, and subtle elevations of CA 19-9 in diabetics should be considered as the indication of exocrine pancreatic dysfunction. | Oya Uygur-Bayramicli Resat Dabak Ekrem Orbay Can Dolapclo■lu Mehmet Sargin Gamze Kilico■lu Yüksel Güleryüzlü Alpaslan Mayada■li | 2007 | World Journal of Gastroenterology2007，13，40： | 63 |
| 2 | Vasculogenic mimicry is a prognostic factor for postoperative survival in patients with glioblastoma显示文摘A previous report has confirmed the existence and clinical significance of vasculogenic mimicry(VM)in glioma.However,its conclusions about the negative clinical significance of VM in glioblastoma are based on a small group of patients and,thus,might be unconvincing.The aim of the present study was to reevaluate the clinical significance of VM in glioblastoma.Patients were classified as VM-positive or | Wang SY Ke YQ Lu GH Song ZH Yu L Xiao S Sun XL Jiang XD Yang ZL Hu CC | 2013 | 中国神经肿瘤杂志2013，11，3： | 22 |
| 3 | Study on the expression of matrix metalloproteinase-2 mRNA in human gastric cancer显示文摘 | Ji F Wang WL Yang ZL Li YM Huang HD Chen WD | 1999 | World Journal of Gastroenterology1999，5，5： | 19 |
| 4 | Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis显示文摘 | Liu Y Li M Zhou PR Xing XP Xia WB Xu L Liu H J Zhang ZL LiaoEY Chen DC Liu J Tao TZ Wu W | 2014 | Chinese Medical Journal2014，，4： | 16 |
| 5 | The effect of retinoic acid on Ito cell proliferation and content of DNA and RNA显示文摘 | Gao ZL Li DG Lu HM Gu XH | 1999 | World Journal of Gastroenterology1999，5，5： | 13 |
| 6 | ANOMALOUS BEHAVIOR REVISITED:DYNAMIC RESPONSE OF ELASTIC-PLASTIC STRUCTURES显示文摘Based on the minimum principle of acceleration in the elastic-plastic continua under fi-nite deformation,the dynamic response of an elastic-perfectly plastic pin-ended beam subjected to rect-angular impulse loading is studied with the help of a numerical approach.The calculated results once a-gain show the anomalous behavior of the beam during its response process,which was previously foundin[1].By carefully analyzing the instantaneous distribution of the bending moment,the membraneforce,the curvature and displacement during the response process,it is concluded that the interactiveeffect between the geometry and materials nonlinearities of the structure is the key reason for leading tothe anomalous behavior.This will be helpful for clarifying some misunderstandings in explaining theproblem before. | Xi, F Yang, JL Li, ZL | 1998 | Acta Mechanica Solida Sinica1998，11，4： | 7 |
| 7 | Study on the Removal of Ammonia Nitrogen from Wastewater Using Microwave Coupled with Active Carbon显示文摘[Objective]The study aimed to discuss the feasibility and optimal conditions of removing ammonia nitrogen by using microwave coupled with active carbon. [Method]In the study,a novel process,microwave radiation coupled with active carbon,was applied to remove ammonia nitrogen from wastewater,and the influences of solution pH,air conditions,active carbon usage,microwave power and time on the removal effect of ammonia nitrogen were studied. [Result]Microwave coupled with active carbon can remove ammonia nitrogen efficiently,and pumping air into the wastewater can also increase the removal rate of ammonia nitrogen to a certain extent. Higher pH,intensive microwave power and longer treating time could also increase the removal rate of ammonia nitrogen using microwave radiation coupled with active carbon,whereas the usage of active carbon contributed a small impact. It was proved that microwave coupled with active carbon was an effective method for the removal of ammonia nitrogen from wastewater. Meanwhile,the orthogonal experiment results showed that the removal rate of ammonia nitrogen reached 92. 5% under the optimal conditions,that is,the usage of active carbon was 0. 5 g,pH =11,microwave radiation power was 850 W,and microwave action time was 4 minutes. [Conclusion]The research provided a new method to remove ammonia nitrogen from wastewater,namely microwave coupled with active carbon. | Zl Pei-jian CHEN Can DAI You-zhi CHENG Ying-xiang XIANG Ren-jun | 2012 | Meteorological and Environmental Research2012，3，7： | 4 |
| 8 | The Photochemical Study of HSA and BSA with Resonance Light Scattering and Fluorescence Spectra显示文摘The resonance light-scattering (RLS) of human serum albumin (HSA) and bovine serum albumin (BSA) is reported for the first time, and applied to study photochemical reaction of HSA and BSA. The fact of photocrosslinking self-association effect in HSA and BSA solutions is identified by the enhancement of RLS. The fluorescence quenching at about 350 um and 700 um proves that tryptophan (Trp) residues are one of the photochemical activity sites in HSA and BSA molecules. The Rayleigh scattering (RS) spectra of HSA and BSA that were neglected in fluorescence spectra before are found at about 296 um, 592 um and 888 um for the first time, and are of adventageous to studying the aggregation of HSA or BSA. The possible photochemical reaction mechanism is also proposed. | Liang, H Shen, XC Li, F Jiang, ZL | 2000 | Chinese Chemical Letters2000，11，3： | 4 |
| 9 | Behaviour of Hydrogen in Nano-transition Metals显示文摘Nanocrystalline transition metals were prepared with Ar+H2 arc plasma method. The hydrogenmust be used during preparation to get a special nanrvparticles. The hydrogen plays an importantrole in the structure and state of nanocrystalline transition metals. The state of hydrogen andthe change of the nanocrystalline metal structure caused by hydrogen are called the behaviour ofhydrogen in nano-transition metals which includes the ability and function of storing hydrogenin the metals. | Zhang, ZK Cui, ZL Chen, KZ Zuo, DH Dong, LF | 1996 | Journal of Materials Science & Technology1996，12，1： | 4 |
| 10 | Small interfering RNA inhibits SARS-CoV nucleocapsid gene expression in cultured cells and mouse muscles显示文摘 | Zhao P Qin ZL Ke JS Lu Y Liu M Pan W Zhao LJ Cao J Qi ZT | 2005 | 第二军医大学学报2005，26，10： | 4 |
| 11 | Structure of nano-copper and nano-conductive fibers显示文摘VARIOUS small inorganic solid grain catalysts, alloys and films consisting of various nano-size particles were prepared by chemical methods. The study of catalytic properties of nanostructured materials integrated material physics with chemistry, which promoted the development of materials science. | Zhang, ZK Cui, ZL Chen, KZ Wang, YN Ning, YP | 1997 | Chinese Science Bulletin1997，42，18： | 4 |
| 12 | Comparisons of grain size characteristics of red earth from southern China with that of loess and dune sand from Beijing region显示文摘The comparisons of grain size distributions among eolian deposits along the monsoon wind trajectory are a fundamental task for the reconstruction of the past wind regimes. Here the authors sampled the dune sands in Hunsandak desert, loess deposits in Beijing region and red earth in southern China. Grain size analyses show that the distribution models of the loess | Xiong, SF Ding, ZL Liu, DS | 1999 | Chinese Science Bulletin1999，44，18： | 3 |
| 13 | Gene splicing by overlap extention:tailor-made genes using the polymerase chain reaction显示文摘 | Horton RM Cai ZL Ho SN | 1990 | Biotechniques1990，8，5： | 2 |
| 14 | Preparation and characterization of highly active nanosized strontium-doped lanthanum cobaltate catalysts with high surface areas显示文摘La1?xSrxCoO3?δ (x=0, 0.4) nanoparticles have been prepared using the citric acid complex-ing-hydrothermal synthesis coupled method and citric acid complexing method. The physico-chemical properties of these materials were characterized by means of X-ray diffraction (XRD), high resolution scanning electron microscopy (HRSEM), element analysis (EDX), X-ray photoelectron spectroscopic (XPS), oxygen temperature-programmed desorption (O2-TPD), hydrogen temperature-programmed re-duction (H2-TPR) as well as surface area measure-ments and oxidation state titration. Their catalytic performance was examined for the total oxidation of ethylacetate (EA). It is found that the La1?xSrxCoO3?δ (x=0, 0.4) catalysts were single-phase and rhombo-hedrally-structured perovskites and their surface ar-eas ranged from 16 to 26 m2/g. The Sr-doped sample derived from the coupled procedure was uniformly distributed nanoparticles with a short rod-shaped morphology. The doping of Sr (i) enhanced the con-centrations of Co3+ and oxygen vacancies, (ii) in-creased the amount of oxygen adsorbed on the sur-face at low temperatures, (iii) promoted the mobility of lattice oxygen, and (iv) improved the properties of redox. The La0.6Sr0.4CoO2.78 catalyst prepared by the citric acid complexing-hydrothermal synthesis cou-pled strategy performed the best in the oxidation of EA, furthermore no partially oxidized products were formed. Based on the above results, we conclude that in addition to the surface area, the catalytic ac-tivity of the perovskite-type oxide nanoparticles was associated with the structural defect (oxygen vacancy) concentration and redox ability. | NIU Jianrong LIU Wei DAI Hongxing HE Hong Zl Xuehong LI Peiheng | 2006 | Chinese Science Bulletin2006，51，14： | 2 |
| 15 | Anthocyanin pigments of a sweet potatoes显示文摘 | Shi ZL Bassa IA Gabriel SL | 1992 | Food Sci1992，57，3： | 2 |
| 16 | In vivo transfeetion of NF-κB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats 显示文摘 | Cao CC Ding XQ Ou ZL | 2004 | Kidney Int2004，65，3： | 1 |
| 17 | Nitrogen source and minerial optimization enhance D-xylose conversion to ethanol by yeast Pichia stipitis NRRL Y-TI24显示文摘 | Slininger PJ Dien BS Gorsich SW Liu ZL | 2006 | Applied microbiology and biolechnology2006，72，： | 1 |
| 18 | Total sacretomy and Galvestont rod reconstruction for malignant neoplasns显示文摘 | Gokaslan ZL Romsdahl MM Kroll SS | 1997 | J Neurosurg1997，87，5： | 1 |
| 19 | Mixed-valent oxide-catalytic carbonization for synthesis of monodispersed nano sized catkin spheres显示文摘 | Wang ZL | 1996 | Philosophical magazine β-physics of condensed matter statistical mechanics electronic optical and magnetic properties1996，73，6： | 1 |
| 20 | Overexpression of YKL-40 is an inde- pendent prognostic marker in gastric cancer 显示文摘 | BiJ Lau SH Lv ZL | 2009 | Hum Pathol2009，40，12： | 1 |
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