| 5 | Multicenter Antimicrobial Resistance Surveillance of Clinical Isolates from Major Hospitals—China,2022显示文摘Summary What is already known about this topic?Bacterial resistance surveillance is crucial for monitoring and understanding the trends and spread of drug-resistant bacteria.What is added by this report?The number of strains collected in 2022 increased compared to 2021.The top five bacteria,including Escherichia coli,Klebsiella pneumoniae,Staphylococcus aureus,Pseudomonas aeruginosa,and Acinetobacter baumannii,remained largely unchanged.The detection rate of methicillin-resistant strains continued to decrease.Among clinical Enterobacterales isolates,the resistance rate to carbapenems was generally below 13%,except for Klebsiella spp.,which had a resistance range of 20.4%to 21.9%.Most clinical Enterobacterales isolates were highly susceptible to tigecycline,colistin,and polymyxin B,with resistance rates ranging from 0.1%to 12.6%.The detection rate of meropenem-resistant P.aeruginosa and meropenemresistant Acinetobacter baumannii showed a decreasing trend for the fourth consecutive year.What are the implications for public health practice?Multidrug-resistant bacteria remain a significant public health challenge in clinical antimicrobial treatment.To effectively address bacterial resistance,it is essential to enhance both bacterial resistance surveillance and the prudent use of antimicrobial agents. | Yan Guo Li Ding Yang Yang Renru Han Dandan Yin Shi Wu Demei Zhu Fupin Hu | 2023 | China CDC weekly2023，5，52： | 0 |
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