维普期刊资源整合服务平台（V6.5）

107篇 您的检索式：作者名="ZHE J"

选中清除导出查看参考文献查看引证文献引用追踪共6页首页上一页第1页下一页末页 /6 跳转

	题名	作者	年代	出处	被引量
1	Caspase-12 mediates carbon tetrachloride-induced hepatocyte apoptosis in mice显示文摘AIM:To investigate the role of caspase-12 and its downstream targets in carbon tetrachloride(CCl4)-induced hepatocyte apoptosis.METHODS:The role of caspase-12 was determined by using caspase-12 knock-out(-/-)mice.CCl4(300μL/kg body weight)or vehicle(corn oil)was administered to caspase-12+/+or caspase-12-/-mice as a single intraperitoneal injection.The animals were sacrificed24 h after the CCl4 treatment.Blood was collected to evaluate liver function by the measurement of the activity of alanine aminotransferase.Liver samples were used for the measurements of reactive oxygen species using plasma malondialdehyde as biomarker,hepatocyte apoptosis was evaluated via terminal transferasemediated d UTP nick-end labeling and controlled by morphologic study,and cytochrome C release and caspase activations were measured by Western blotting.RESULTS:Administration of a low dose of CCl4resulted in hepatocyte apoptosis and acute liver injury in wild-type mice.CCl4 also induced the generation of reactive oxygen species and induction of endoplasmic reticulum stress in the liver followed by activations of caspase-12,-9 and-3 as well as release of small amounts of cytochrome C.However,in the CCl4-treated caspase-12-/-mice,activation of caspase-9 and-3 were significantly attenuated(P<0.05);no effect was seen in cytochrome C release.CCl4-induced apoptosis and liver damage was markedly reduced in caspase-12-/-mice compared to caspase-12+/+mice(P<0.05).The active form of caspase-8 was not detected in either caspase-12+/+or caspase-12-/-mice.There was no significant different in the formation of reactive oxygen species in the livers of caspase-12+/+and caspase-12-/-mice treated with CCl4.CONCLUSION:Caspase-12 plays a pivotal role in CCl4-induced hepatic apoptosis through the activation of the downstream effector caspase-3 directly and/or indirectly via capase-9 activation.	Hua Liu Zhe Wang Michael J Nowicki	2014	World Journal of Gastroenterology2014，20，48：	18
2	Characteristics of Proinflammatory Cytokines and Chemokines in Airways of Asthmatics: Relationships with Disease Severity and Infiltration of Inflammatory Cells显示文摘	Ting Yang Yan Li Zhe Lyu Kewu Huang Chris J Corrigan Sun Ying Wei Wang Chen Wang	2017	Chinese Medical Journal2017，，17：	12
3	Interpretation and compensation of backlash error data in machine centers for intelligent predictive maintenance using ANNs显示文摘It is especially significant for a manufacturing company to select a proper maintenance policy because maintenance impacts not only on economy,reliability and availability but also on personnel safety.This article reports on research in the backlash error data interpretation and compensation for intelligent predictive maintenance in machine centers based on artificial neural networks(ANNs).The backlash error,measurement system and prediction methods are analyzed in detail.The result indicates that it is possible to predict and compensate for the backlash error in both forward and backward directions in machine centers.	Ke-Sheng Wang Zhe Li JФrgen Braaten Quan Yu	2015	Advances in Manufacturing2015，3，2：	2
4	Pulse wave velocity is associated with metabolic syndrome components in CAPD patients显示文摘	Zhe XW Zeng J Tian XK	2008	Am J Nephrol2008，28，4：	1
5	A high throughput inductive pulse sensor for online oil debris monitoring 显示文摘	L Du J Zhe	2011	Tribology International2011，44，2：	1
6	Analytical and finite element model pull-in study of rigid and deformable electrostatic microactuators 显示文摘	CHENG J ZHE J WU X T	2004	J Micromech Microengineer2004，14，：	1
7	Numerical seismogram computations for inhomogeneous media using a short, variable length convolutional differentiator显示文摘	ZHOU B GREEHALGH S A ZHE J	1993	Geophysical Prospecting1993，41，：	1
8	In vitro studies on cellular and molecular mechanisms of arsenic trioxide in the treatment of acute promyelocytic leukemia:As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML protein显示文摘	Chen G Q Zhe J Shi X G	1996	Blood1996，88，3：	1
9	Optimal Two-threshold Polices in an M/G/1 Queue With Two Vacation Types显示文摘	Raymond G Vickson Michel J A Van Eenige	1997	Performance Evaluation1997，29，：	1
10	Prevalence of verocytotoxigenieEshehefiehia coil serotype 01, I:H7 in children with diarrhoea attendingaSydney hospital显示文摘	Ony J Zhe L Robins Browne R	1993	Jpaediatr Child Health1993，29，3：	1
11	Observation of Exchange Bias in the Martensitic State of Ni50Mn36Sn14 Heusler Alloy显示文摘	Zhe L Chao J Jiping C	2007	App-lied Physics Letters2007，91，11：	1
12	A simplified multi-class support vector machine with reduced dual optimization显示文摘	HE Xi-sheng ZHE Wang Cheng J in	2012	Pattern Recognition Letters2012，33，1：	1
13	Prevalence of verocytotoxigenic Eshcherichia coli serotype O157:H7 in children with diarrhoea attending sydney hospital显示文摘	Ony J Zhe L Robinsb R	1993	Paediatr Child Health1993，29，3：	1
14	Critical role of cy- clophilin A and its prolyl-peptidyl isomerase activity in the struc- ture and function of the hepatitis C virus replication complex 显示文摘	Liu Zhe Yang Feng Robotham J M	2009	J Virol2009，83，13：	1
15	Nrf2 protects against As(III) -induced damage in mouse liver and bladder 显示文摘	Tao J Zhe PH Jefferson YC	2009	Toxicology and Applied Pharmacology2009，240，：	1
16	Parallel sensing of metallic wear debris inlubricants using undersampling data processing 显示文摘	DU L ZHE J	2012	Tri- bology International2012，53，9：	1
17	Partial hydrogenation of benzene to cyclohexene on a Ru-Zrdm-ZrO2 nanocomposite catalyst显示文摘	J Q Wang ' Y Z Wang S H Zhe	2004	Applied Catalysis A-General2004，272，12：	1
18	Prestack multicomponent migration 显示文摘	Zhe J P Greenhalgh S A	1997	Geophysics1997，62，2：	1
19	Prestack multicomponent migration显示文摘	Zhe J Greenhalgh S A		0，，4：	1
20	A Novel Measurement-based Algorithm for Coverage Prediction of Urban and Suburban Cells in Wireless Networks 显示文摘	J S Xu Y H Wang Zhe Wang	2006	IEEE Transactions on Antennas and Propagation (S0018-926X)2006，54，11：	1

返回顶部每页显示：

共6页首页上一页第1页下一页末页 /6 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示