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| 1 | 亚太地区慢性乙型肝炎治疗共识(2012最新版)显示文摘自2008年至今,有大量关于慢性HBV感染的自然史和治疗的最新数据不断涌现。其中包括慢性HBV感染的无症状感染者,以社区为基础的队列研究,HBV基因型的作用,非药物诱导的自然HBV变异型毒株,无创性肝纤维化评估方法的应用,HBsAg定量在临床中的应用,更有效的新治疗药物和新治疗方案等等。来自亚太地区的专家审查和评估了相关数据,并共同商讨了近年来报道的最有意义的发现,基于此,对2008年版的亚太地区慢性乙型肝炎治疗共识进行修订,同时对2008年版治疗指南定义的关键词组进行了修订。修订后的指南包括以下几方面内容:一般治疗,肝纤维化评价适应证,何时开始治疗或停药,初始抗病毒治疗药物的选择,如何监测治疗中和治疗后的患者。关于特殊人群的治疗建议中包括了对妊娠妇女,已发生耐药,合并其他病毒感染,肝功能失代偿,接受免疫抑制治疗、化疗,肝移植或肝细胞癌患者的具体治疗建议。 | 廖运范 Jia-HorngKao Teerha Piratvisuth Henry Lik Yuen Chan Rong-Nan Chien Chun-Jen Liu Ed Gane Stephen Locarnini Seng-Gee Lim Kwang-Hyub Han Deepak Amarapurkar Graham Cooksley Wasim Jafri Rosmawati Mohamed Wan-Long Chuang Laurentius A.Lesmana Jose D.Sollano Dong-Jin Suh Masao Omata 刘颖 徐莹 李芸 黄祖雄 樊蓉 李小溪 吕国涛 周彬 孙剑 侯金林 | 2012 | 临床肝胆病杂志2012，28，8： | 182 |
| 2 | 基于深度学习卷积神经网络的地震波形自动分类与识别显示文摘发展高效、高精度、普适性强的自动波形拾取算法在地震大数据时代背景下显得越来越重要.波形自动拾取算法的主要挑战来自如何适应不同区域的不同类型地震事件的分类与筛选.本文针对地震事件-噪音分类这一问题,使用13839个汶川地震余震事件建立数据集,应用深度学习卷积神经网络(CNN)方法进行训练,并用8900个新的汶川余震事件作为检测数据集,其训练和检测准确率均达到95%以上.在对连续波形的检测中,CNN方法在精度和召回率上优于STA/LTA和Fbpicker传统方法,并能找出大量人工挑选极易遗漏的微震事件.最后,我们应用训练好的最优模型对选自全国台网的441个台站8天的连续波形数据进行了识别、到时挑取及与参考地震目录关联,CNN检出7016段波形,用自动挑选算法拾取到1380对P,S到时,并与540个地震目录事件成功关联,对1级以上事件总体识别准确率为54%,二级以上为80%,证明了CNN模型具有泛化能力,初步展示了CNN在发展兼具效率、精度、普适性算法,实时地震监测等应用上具有巨大潜力. | 赵明 陈石 Dave Yuen | 2019 | 地球物理学报2019，62，1： | 82 |
| 3 | Natural history of hepatitis-related hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is an important cause of cancer death in the world.It has great regional differences in the pathology and epidemiology.The variation is greatly influenced by the aetiologies of the disease.Hepatitis B and C infection are the most important risk factors.HCC incidence rates are higher but in decreasing trend in developing countries. However,the figures in the developed countries are contrary.Successful hepatitis B virus(HBV)vaccination programs,better food hygiene,increased global hepatitis C virus(HCV)prevalence and population migration are the possible explanations.A number of clinical and pathogenic differences exist between HBV- and HCV- related HCC.HBV infection leads to the development of HCC through direct and indirect pathways as it has the ability to integrate into the host genome affecting cellular signaling and growth control.HCV causes HCC mainly through indirect pathways:chronic inflammation, cell deaths and proliferation.As a result,HCC is almost exclusively found in cirrhotic HCV patients while HCC is sometimes found in HBV patients without significant liver cirrhosis.Due to the different severities of liver cirrhosis and HCC extent,therapeutic strategies from resection, liver transplantation to symptoms palliation are available. Poorly differentiated histology,lack of fibrous capsule, large tumour size,early vascular invasion and elevated serum levels of alpha fetoprotein(AFP)are the features for more aggressive disease.Combined with markers of liver reserve and performance status,accurate scoring systems and models have been developed to predict patients'survival and match best treatment option. | David Yiu-Kuen But Ching-Lung Lai Man-Fung Yuen | 2008 | World Journal of Gastroenterology2008，14，11： | 56 |
| 4 | 基于U形卷积神经网络的震相识别与到时拾取方法研究显示文摘精确获取震相到时是地震定位和地震走时成像等研究的重要基础.近年来,随着地震台站的不断加密,地震台网监测到的地震数量成倍增长,发展快速、准确、适用性强的震相到时自动拾取算法是地震行业的迫切需求.本文在前人工作基础上,发展了Pg、Sg震相自动识别与到时拾取的U网络算法(Unet_cea),使用汶川余震和首都圈地震台网记录的89344个不同震级、不同信噪比的样本进行训练和测试.研究表明,U网络能够较好地识别Pg、Sg震相类型和拾取到时,Pg、Sg震相的正确识别率分别为81%和79.1%,与人工标注到时的均方根误差分别为0.41s和0.54s.U网络在命中率、均方根误差等性能指标上均明显优于STA/LTA和峰度分析自动拾取方法.研究获得的最优模型可以为区域地震台网的自动处理提供辅助. | 赵明 陈石 房立华 David A Yuen | 2019 | 地球物理学报2019，62，8： | 55 |
| 5 | 癌症患者家庭照顾者的研究现状显示文摘根据WHO报道,2005年有760万人死于肿瘤。占全球死亡人数的13%,2005~2015年预计将有8400多万人死亡。70%以上肿瘤死亡者发生在低收入和中等收入国家,预计到2030年肿瘤死亡人数将超过1100万/年。近年来随着临床新治疗方法和手段的不断应用,癌症患者5年存活率已达到68%。随着癌症患者5年生存率的提高,癌症对家庭照顾者的影响越来越受到关注。 | 李秋萍 Alice Yuen Loke | 2012 | 中华护理杂志2012，47，12： | 48 |
| 6 | 新加坡最大回用水处理厂污水短程硝化厌氧氨氧化脱氮工艺显示文摘总结了新加坡樟宜回用水处理厂4次采样的结果,该厂日处理城市污水80万t.在好氧区很好地实现了部分硝化和亚硝酸盐积累,其中好氧氨氧化率平均为72.2%,亚硝酸盐积累率平均为76.0%.在缺氧区氨氮和亚硝酸盐得到了同步去除(厌氧氨氧化).物料衡算结果表明:初沉池的出水总氮的37.5%是通过自养脱氮去除,27.1%是通过传统的硝化/反硝化脱氮去除,其余部分总氮则存在于活性污泥和出水中.微生物和动力学研究表明:短悬浮或游离的厌氧氨氧化菌可存在于污泥龄较短的污水处理系统.最后从出水氮质量浓度、pH、碱度、曝气能耗及反应器容积等方面,将樟宜回用水处理厂的分段进水活性污泥法工艺与新加坡其他3个回用水处理厂的MEL/LE工艺进行了对比分析. | Cao Yeshi Kwok Bee Hong Yan Zhou Yu Liu He Jianzhong Chua Seng Chye Wah Yuen Long Yahya Ghani | 2015 | 北京工业大学学报2015，41，10： | 32 |
| 7 | Gestational diabetes mellitus: Challenges for different ethnic groups显示文摘Ethnicity is defined as'belonging to a social groupthat has a common national or cultural tradition'.Membership of certain ethnic groups has long been associated with increased risk of gestational diabetes mellitus(GDM).Studies that examined ethnic differences amongst women with GDM were often conducted in western countries where women from various ethnic backgrounds were represented.The prevalence of GDM appears to be particularly high among women from South Asia and South East Asia,compared to Caucasian,African-American and Hispanic communities.For some,but not all ethnic groups,the body mass index is a risk factor for the development of GDM.Even within a particular ethnic group,those who were born in their native countries have a different risk profile for GDM compared to those born in western countries.In terms of treatment,medical nutrition therapy(MNT)plays a key role in the management of GDM and the prescription of MNT should be culturally sensitive.Limited studies have shown that women who live in an English-speaking country but predominantly speak a language other than English,have lower rates of dietary understanding compared with their English speaking counterparts,and this may affect compliance to therapy.Insulin therapy also plays an important role and there appears to be variation as to the progression of women who progress to requiring insulin among different ethnicities.As for peri-natal outcomes,women from Pacific Islander countries have higher rates of macrosomia,while women from Chinese backgrounds had lower adverse pregnancy outcomes.From a maternal outcome point of view,pregnant women from Asia with GDM have a higher incidence of abnormal glucose tolerance test results post-partum and hence a higher risk of future development of type2 diabetes mellitus.On the other hand,women from Hispanic or African-American backgrounds with GDM are more likely to develop hypertension post-partum.This review highlights the fact that management needs to be individualised and the clinician should be mindful of the impact that differences in ethnicity may have on the clinical characteristics and pregnancy outcomes inwomen affected by GDM,particularly those living in Western countries.Understanding these differences is critical in the delivery of optimal antenatal care for women from diverse ethnic backgrounds. | Lili Yuen Vincent W Wong | 2015 | World Journal of Diabetes2015，6，8： | 29 |
| 8 | Atomically dispersed Au_1 catalyst towards efficient electrochemical synthesis of ammonia显示文摘Tremendous efforts have been devoted to explore energy-efficient strategies of ammonia synthesis to replace Haber–Bosch process which accounts for 1.4% of the annual energy consumption. In this study,atomically dispersed Au_1 catalyst is synthesized and applied in electrochemical synthesis of ammonia under ambient conditions. A high NH_4^+ Faradaic efficiency of 11.1% achieved by our Au_1 catalyst surpasses most of reported catalysts under comparable conditions. Benefiting from efficient atom utilization, an NH_4^+ yield rate of 1,305 lg h^(-1) mg_(Au)^(-1) has been reached, which is roughly 22.5 times as high as that by supported Au nanoparticles. We also demonstrate that by employing our Au_1 catalyst, NH4+can be electrochemically produced directly from N_2 and H_2 with an energy utilization rate of 4.02 mmol kJ^(-1). Our study provides a possibility of replacing the Haber–Bosch process with environmentally benign and energy-efficient electrochemical strategies. | Xiaoqian Wang Wenyu Wang Man Qiao Geng Wu Wenxing Chen Tongwei Yuan Qian Xu Min Chen Yan Zhang Xin Wang Jing Wang Jingjie Ge Xun Hong Yafei Li Yuen Wu Yadong Li | 2018 | Science Bulletin2018，63，19： | 22 |
| 9 | Recent advances in the precise control of isolated single-site catalysts by chemical methods显示文摘The search for constructing high-performance catalysts is an unfailing topic in chemical fields. Recently, we have witnessed many breakthroughs in the synthesis of single-atom catalysts(SACs) and their applications in catalytic systems. They have shown excellent activity, selectivity, stability, efficient atom utilization and can serve as an efficient bridge between homogeneous and heterogenous catalysis. Currently, most SACs are synthesized via a bottom-up strategy; however, drawbacks such as the difficulty in accessing high mass activity and controlling homogeneous coordination environments are inevitably encountered, restricting their potential use in the industrial area. In this regard, a novel top-down strategy has been recently developed to fabricate SACs to address these practical issues. The metal loading can be increased to 5% and the coordination environments can also be precisely controlled. This review highlights approaches to the chemical synthesis of SACs towards diverse chemical reactions, especially the recent advances in improving the mass activity and well-defined local structures of SACs. Also, challenges and opportunities for the SACs will be discussed in the later part. | Zhijun Li Dehua Wang Yuen Wu Yadong Li | 2018 | National Science Review2018，5，5： | 21 |
| 10 | The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORCl显示文摘 | Carsten Gram Hansen Yuen Lam Dora Ng Wai-Ling Macrina Lam Steven W Plouffe Kun-Liang Guan | 2015 | Cell Research2015，25，12： | 19 |
| 11 | 舌癌CN0患者选择性颈淋巴清扫和颈部观察的前瞻性随机研究显示文摘Prospective randomized study of selective neck dissection versus observation for NO neck of early tongue carcinoma. Yuen AP, Ho CM, Chow TL, et al. Head Neck, 2009, 31(6):765-772. | Yuen AP Ho CM Chow TL | 2009 | 中国口腔颌面外科杂志2009，7，4： | 16 |
| 12 | Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection显示文摘AIM:To test the psychometric properties of a Chinese [(Hong Kong) HK] translation of the chronic liver disease questionnaire (CLDQ).METHODS:A Chinese (HK) translation of the CLDQ was developed by iterative translation and cognitive debriefing.It was then administered to 72 uncomplicated and 78 complicated chronic hepatitis B (CHB) patients in Hong Kong together with a structured questionnaire on service utilization,and the Chinese (HK) SF-36 Health Survey Version 2 (SF-36v2).RESULTS:Scaling success was ≥ 80% for all but three items.A new factor assessing sleep was found and items of two (Fatigue and Systemic Symptoms) subscales tended to load on the same factor.Internal consistency and test-retest reliabilities ranged from 0.58-0.90 for different subscales.Construct validity was confirmed by the expected correlations between the SF-36v2 Health Survey and CLDQ scores.Mean scores of CLDQ were significantly lower in complicated compared with uncomplicated CHB,supporting sensitivity in detecting differences between groups.CONCLUSION:The Chinese (HK) CLDQ is valid,reliable and sensitive for patients with CHB.Some modif ications to the scaling structure might further improve its psychometric properties. | Elegance Ting Pui Lam Cindy Lo Kuen Lam Ching Lung Lai Man Fung Yuen Daniel Yee Tak Fong | 2009 | World Journal of Gastroenterology2009，15，26： | 16 |
| 13 | Recent advances in diagnostic upper endoscopy显示文摘BACKGROUND Esophageo-gastro-duodenoscopy(EGD)is an important procedure used for detection and diagnosis of esophago-gastric lesions.There exists no consensus on the technique of examination.AIM To identify recent advances in diagnostic EGDs to improve diagnostic yield.METHODS We queried the PubMed database for relevant articles published between January 2001 and August 2019 as well as hand searched references from recently published endoscopy guidelines.Keywords used included free text and MeSH terms addressing quality indicators and technological innovations in EGDs.Factors affecting diagnostic yield and EGD quality were identified and divided into the follow segments:Pre endoscopy preparation,sedation,examination schema,examination time,routine biopsy,image enhanced endoscopy and future developments.RESULTS We identified 120 relevant abstracts of which we utilized 67 of these studies in our review.Adequate pre-endoscopy preparation with simethicone and pronase increases gastric visibility.Proper sedation,especially with propofol,increases patient satisfaction after procedure and may improve detection of superficial gastrointestinal lesions.There is a movement towards mandatory picture documentation during EGD as well as dedicating sufficient time for examination improves diagnostic yield.The use of image enhanced endoscopy and magnifying endoscopy improves detection of squamous cell carcinoma and gastric neoplasm.The magnifying endoscopy simple diagnostic algorithm is useful for diagnosis of early gastric cancer.CONCLUSION There is a steady momentum in the past decade towards improving diagnostic yield,quality and reporting in EGDs.Other interesting innovations,such as Raman spectroscopy,endocytoscopy and artificial intelligence may have widespread endoscopic applications in the near future. | Jun-Liang Teh Asim Shabbir Soon Yuen Jimmy Bok-Yan So | 2020 | World Journal of Gastroenterology2020，26，4： | 15 |
| 14 | Clinical application of liver stiffness measurement using transient elastography in chronic liver disease from longitudinal perspectives显示文摘Accurate determination of the presence and degree of fibrosis in liver is of great importance, because the prognosis and management strategies for chronic liver disease depend mainly on these factors. To date, liver biopsy (LB) remains the 'gold standard' for assessing the severity of liver fibrosis; however, LB is often limited by its invasiveness, sampling error, and intra/ inter-observer variability in histological interpretation. Furthermore, repeated LB examinations within a short time interval are indeed ineligible in a real clinical practice. Thus, due to the pressing need for non-invasive surrogates for liver fibrosis, transient elastography (TE),as a novel ultrasound based technology, has allowed a noninvasive measurement of liver stiffness and has gained in popularity over recent years. In the past few years, additional roles for transient TE beyond the initial purpose of a non-invasive surrogate for LB have included the prediction of the most two critical consequences of fibrosis progression: the development of portal hypertension-related complications and hepatocellular carcinoma. This indicates that the role of transient TE is not merely limited to reducing the need for LB, but transient TE can enable the establishment of tailored management strategies by providing more detailed prognostic information. In particular, under the concept in which the clinical course of liver fibrosis is dynamic and bidirectional, especially when appropriate intervention is commenced, transient TE can be used to track the dynamic changes in fibrotic burden during antiviral or antifibrotic treatment. This review discussed extended applications of transient TE in prediction of the development of real clinical endpoints from a longitudinal perspective. | Beom Kyung Kim James Fung Man-Fung Yuen Seung Up Kim | 2013 | World Journal of Gastroenterology2013，19，12： | 14 |
| 15 | A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein显示文摘最新新兴的中东呼吸症候群 coronavirus (MERS-CoV ) 能在人引起严重、致命的急性呼吸疾病。尽管有全球努力,潜力为一联系在未来流行不能被排除。有效相对的措施的发展是迫切的。MERS-CoV-specific 抗病毒的药或疫苗是还没可得到的。使用 MERS-CoV (MERS-RBD ) 的尖铁受体绑定领域使老鼠免疫,我们识别了二抵销 monoclonal 抗体(mAbs ) 4C2 和 2E6。两 mAbs potently 与高功效在 vitro 绑在 MERS-RBD 和块病毒入口。我们进一步由使在 Fab 碎片和 RBD 之间的建筑群结晶调查了他们中立化的机制,并且解决了 4C2 Fab/MERS-RBD 建筑群的结构。结构证明 4C2 认出部分重叠的 epitope 在 MERS-RBD 的受体绑定脚印,从而由位的阻碍者和接口残余竞争防碍病毒 / 受体相互作用。2E6 也堵住受体绑定,并且为绑定与 4C2 竞争到 MERS-RBD。基于结构,我们进一步由保存仅仅 paratope 残余并且从人的免疫球蛋白与对应物代替留下的氨基酸使 4C2 人性化。人性化的 4C2 (4C2h ) 抗体支撑了类似的抵销的活动和生物化学的特征到父母老鼠抗体。最后,我们证明 4C2h 能显著地在感染 MERS-CoV 的 Ad5-hCD26-transduced 鼠标的肺消除病毒 titers,因此在临床的设置为预防和治疗代表一个有希望的代理人。 | Yan Li YuhuaWan Peipei Liu Jincun Zhao Guangwen Lu Jianxun Qi Qihui Wang Xuancheng LU Ying Wu Weniun Liu Buchang Zhang Kwok-Yung Yuen Stanley Perlman George F Gao Jinghua Yan | 2015 | Cell Research2015，25，11： | 14 |
| 16 | Evaluation of a simulation-based workshop on clinical performance for emergency physicians and nurses显示文摘BACKGROUND: Simulation-based medical education has been growing rapidly and becomes one of the most popular teaching methods for improving patient safety and patient care. The Simulation Subcommittee of the Hong Kong College of Emergency Medicine organized an educational program emphasizing the team training, clinical decision-making and communication skills. This study aimed to evaluate the attitude of the participants toward a new training program and the change in the knowledge on clinical performance in emergency physicians and nurses after attending the educational program.METHODS: A course evaluation form was filled in by the participants at the end of the workshop. An assessment of 20 multiple-choice questions with 5 options was administered to the participants before and after the 2-day simulation-based training workshop.RESULTS: A total of 72 doctors and nurses working in the Accident and Emergency Department were enrolled. The average pretest and posttest scores were 12 and 14.3 respectively. The percentage improvement in the mean score of the pretest and posttest was 11.5%. The Chi-square test showed signifi cant improvement in the pretest and posttest score grading(P=0.00). Paired t-test revealed signifi cant difference between the mean scores of the pretest and posttest(P=0.00).CONCLUSIONS: Participants had positive attitude toward this new training program. Significant improvement of the knowledge on clinical performance in healthcare professionals in the Accident and Emergency Department was observed after the participation in this simulation-based educational program. | Chi Ho Chan Tung Ning Chan Man Cheuk Yuen Wai Kit Tung | 2015 | World Journal of Emergency Medicine2015，6，1： | 14 |
| 17 | The performance characteristics of prostate-specific antigen and prostate-specific antigen density in Chinese men显示文摘我们在中国人调查了前列腺特定的抗原(PSA ) 和 PSA 密度(PSAD ) 的表演特征。经历了 transrectal 的所有中国人到 2013 的从 2000 年的指导超声的前列腺活体检视(TRUS-PB ) 被包括。为 PSA 和 PSAD 操作特征(巨鸟) 曲线的接收装置被分析。敏感,特性,积极预兆的价值(PPV ) 和在不同截止层次的否定预兆的价值(NPV ) 是计算的。2606 个中国人的一个总数被包括。为 ROC,在曲线下面的区域为 PSA 是 0.770 (P <0.001 ) 并且 0.823 为 PSAD (P <0.001 ) 。4.5 ng ml −1 的 PSA 94.4% 的有的敏感, 14.1% 的特性, 29.5% 的 PPV,和 86.9% 的 NPV;0.12 ng ml −1 cc −1 的 PSAD 有 94.5% 的敏感, 26.6% 的特性, 32.8% 的 PPV,和 92.7% 的 NPV。在逻辑回归分析的 multivariate 上,在 4.5 ng ml −1 截止的 PSA (或 1.61, 95% CI 1.05-2.45, P = 0.029 ) 并且在 0.12 ng ml −1 cc 截止的 PSAD −1( 或 6.22, 95% CI 4.20-9.22, P <0.001 ) 是为 TRUS-PB 上的前列腺癌症察觉的重要预言者。在结论,在在中国人的不同截止层次的 PSA 和 PSAD 的表演与在白种人的那些很不同。4.5 ng ml −1 的 PSA 和 0.12 ng ml −1 cc −1 的 PSAD 在 95% 敏感附近有并且是在中国人的前列腺癌症察觉的重要预言者。 | Jeremv YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho Ming-Kwong Yiu | 2017 | Asian Journal of Andrology2017，19，1： | 13 |
| 18 | Systematic review comparing endoscopic, percutaneous and surgical pancreatic pseudocyst drainage显示文摘AIM: To perform a systematic review comparing the outcomes of endoscopic, percutaneous and surgical pancreatic pseudocyst drainage.METHODS: Comparative studies published between January 1980 and May 2014 were identified on Pub Med, Embase and the Cochrane controlled trials register and assessed for suitability of inclusion. The primary outcome was the treatment success rate. Secondary outcomes included were the recurrence rates, re-interventions, length of hospital stay, adverse events and mortalities.RESULTS: Ten comparative studies were identified and 3 were randomized controlled trials. Four studies reported on the outcomes of percutaneous and surgical drainage. Based on a large-scale national study, surgical drainage appeared to reduce mortality and adverse events rate as compared to the percutaneous approach. Three studies reported on the outcomes of endoscopic ultrasound(EUS) and surgical drainage. Clinical success and adverse events rates appeared to be comparable but the EUS approach reduced hospital stay, cost and improved quality of life. Three other studies comparedEUS and esophagogastroduodenoscopy-guided drainage. Both approaches were feasible for pseudocyst drainage but the success rate of the EUS approach was better for non-bulging cyst and the approach conferred additional safety benefits.CONCLUSION: In patients with unfavorable anatomy, surgical cystojejunostomy or percutaneous drainage could be considered. Large randomized studies with current definitions of pseudocysts and longer-term follow-up are needed to assess the efficacy of the various modalities. | Anthony Yuen Bun Teoh Vinay Dhir Zhen-Dong Jin Mitsuhiro Kida Dong Wan Seo Khek Yu Ho | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，6： | 13 |
| 19 | 电线电缆燃烧试验标准溯源与测试体系研究显示文摘针对当前电线电缆燃烧试验标准体系庞大、复杂的实际情况,存在进行电线电缆燃烧试验时对标准的误用现象,对我国电线电缆燃烧试验标准、相关国际标准和国外标准及其关联性进行溯源分析,明确相关标准间的关联和沿袭,从而明确各标准的应用范围,并对当前电线电缆燃烧试验需要改进和开展的内容进行了讨论。 | 张佳庆 范明豪 杜晓峰 武海澄 李伟 李开源 Richard Yuen | 2015 | 绝缘材料2015，48，9： | 12 |
| 20 | Analysis of inborn errors of metabolism: disease spectrum for expanded newborn screening in Hong Kong显示文摘氨基酸,器官的酸和丰满的酸氧化的新陈代谢(IEM ) 的古典先天的错误的背景数据大部分正在缺乏香港,在集体基于 spectrometry 的扩展新生儿为 IEM 屏蔽没被开始的地方。瞄准在香港评估近似发生,光谱和古典 IEM 的另外的特征的当前的学习,将在开发为实验室血浆氨基酸记录的本地 area.Methods 屏蔽节目的一个扩展新生儿重要,血浆 acylcarnitines 和尿从年 2005~2009 的器官的酸分析在为 IEM 提供生物化学、基因的诊断服务的三个地区性的化学病理实验室包括回顾地 reviewed.Resu 在香港的古典 IEM 的发生粗略地被估计每 1000live 出生每 4122 生活出生,或 0.243 个盒子是至少 1 个盒子。这发生类似于全球报导的那些,包括中国的大陆。hyperphenylalaninemia 的估计的发生在 29 542 实时 births.Conclusions 是 1 我们的数据显示它为在香港的扩展新生的屏蔽节目的介绍是无可争辩的。因为香港是一个大城市的城市,一个全面扩展新生的屏蔽程序和工作分派系统应该是可得到的服务在区域出生的出生不满一月的婴儿。 | Han-Chih Hencher Lee Chloe Miu Mak Ching-Wan Lam Yuet-Ping Yuen, Angel On-Kei Chan Chi-Chung Shek Tak-Shing Siu Chi-Kong Lai Chor-Kwan Ching Wai-Kwan Siu Sammy Pak-Lam Chen Chun-Yiu Law Morris Hok-Leung Tai Sidney Tam Albert Yan-Wo Chan | 2011 | Chinese Medical Journal2011，，7： | 12 |
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