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| 1 | 基于单池药物溶出/吸收仿生系统评价格列吡嗪不同制剂的释药特征及其体内外相关性显示文摘[目的]考察格列吡嗪片及其缓释片在单池药物溶出/吸收仿生系统(Single cell-DDASS)的释放特征,以及与比格犬体内吸收程度的相关性。[方法]采用《中华人民共和国药典》(以下简称《药典》)溶出度法和Single cell-DDASS法对格列吡嗪片及其缓释片进行体外释放度实验,用Wagner-Nelson方程计算不同格列吡嗪制剂在体内的吸收百分数,并与相应时间点体外累积释放度进行线性回归,进一步考察其体内外相关性(IVIVC)。[结果]格列吡嗪缓释片体外释放度的最优拟合方程是一级动力学方程,释放机制为溶蚀机制。格列吡嗪片在《药典》溶出法中释放过快,无法建立体内外相关性,而Single cell-DDASS法中累积释放度与比格犬体内吸收百分数之间存在相关性(r=0.773 2,P<0.05)。格列吡嗪缓释片在《药典》溶出法中累积释放度与比格犬体内吸收百分数之间密切相关(r=0.811 5,P<0.05)。格列吡嗪缓释片在Single cell-DDASS法中累积释放度与比格犬体内吸收百分数之间极密切相关(r=0.987 7,P<0.01)。[结论]格列吡嗪片及其缓释片在Single cell-DDASS法中累积释放度与比格犬体内吸收百分数之间的相关性明显优于《药典》溶出法释放百分数与比格犬体内吸收百分数的相关性,表明Single cell-DDASS能够良好预测格列吡嗪不同制剂在体内的动力学特征。 | 寻明金 Yaro Peter 谷升盼 何新 | 2014 | 天津中医药2014，31，2： | 5 |
| 2 | Lead Accumulation in Surface Soils and Components of Balenites Aegyptica Specie in a Katsina Urban Area, Nigeria显示文摘The main objective of this paper is to assess the impact of various vehicular traffic densities on lead (Pb) accumulations in some environmental components in Katsina, a semi-arid urban area of Nigeria. Methods This was achieved by collecting and analyzing samples of surface soils, fruits, kernels, leaves, and barks of Balenites aegyptica from locations of different vehicular traffic densities in the area, and analyzing them for lead, using atomic absorption spectrophotometry. Results The results obtained revealed that the Pb concentration in the high, medium, low, and zero traffic density areas are, 75, 53, 35, and 12 μg·g-1 respectively for the fruit pulp. They are also16, 13, 8, and 6 μg·g-1 for fruit kernel and 44, 28, 17, and 9μg·g-1 respectively for leaves. For tree barks, the values are 138, 97, 64, and 18 μg·g-1 respectively while for under-tree-canopy soil samples the mean values are 99, 74, 44, and 17 μg·g-1. In the case of outside-canopy soil samples, the mean values are 113, 91, 50, and 18 μg·g-1 respectively for the various classes of vehicular traffic density. Conclusion These results indicate a strong influence of vehicular traffic density on Pb emission into surrounding atmosphere and its subsequent precipitation on soil and components of B. aegyptica specie in the area. Of all the samples, tree bark should be the best index of assessing Pb pollution in the area, as it maintains the closest contact with the surrounding atmosphere. Since Pb has no known lower limit for human tolerance, there is an urgent need for Pb pollution control in the area to be effectively enforced. | S. A. MASHI S. A. YARO K. M. GALADANCI | 2005 | Biomedical and Environmental Sciences2005，18，1： | 3 |
| 3 | An assessment of the extent and causes of food insecurity in northern Ghana using a livelihood vulnerability framework显示文摘 | Jan Hesselberg Joseph A. Yaro | 2006 | GeoJournal2006，，1： | 2 |
| 4 | American Spatial Development and the New Megalopolis显示文摘 | Carbonell A Yaro R D | 2005 | Land Lines2005，17，2： | 1 |
| 5 | Musculoskeletal symptoms among dentists in relation to work posture 显示文摘 | RATZON NZ YAROS T MIZLIK A | 2000 | Work2000，15，3： | 1 |
| 6 | Application and circular economy prospects of palm oil waste for eco-friendly asphalt pavement industry:A review显示文摘During the production of palm oil,a significant amount of waste is generated.However,because of inefficient handling and utilization,these wastes are becoming a larger issue.As a result,one initiative is to use these wastes in the pavement industry as sustainable materials.However,there is still a lack of understanding about the wider incorporation of palm oil waste in asphalt pavement and its performance.This study examines existing literature on the use of various wastes in the pavement industry,including palm oil clinker(POC),palm oil fibre(POF),palm kernel shell(PKS),and palm oil fuel ash(POFA).As a result,this paper presents a systematic review and scientometric investigation of related study publications on many uses of palm oil waste in the asphalt pavement industry and its performance from 2009 to 2022.The VOS viewer application was used to conduct the sciento-metric study analysis.The relationship between interactions detected in co-authored country studies cited sources of co-citation,and the keyword of the co-occurrence and publication source enabled the identification of the research gap.According to the systematic literature review,40%–60% POC can be used to fine aggregate for optimal performance,while 0–100%PKS can be used to replace coarse aggregate.In addition,50%–80% POFA or POC fine(POCF)can be used as a filler replacement,5%–8% POCF or POFA as a bitumen modifier,and 0.3% POF as a stabilizing additive.Furthermore,the study demonstrates that the safety of utilizing wastes with more than 50% CO_(2) emissions can be curtailed with minimal heavy metal leaching and radioactivity levels.The scientometric analysis may encourage researchers to seek out gaps in the literature that will aid in the long-term,multifaceted use of palm oil wastes in the asphalt pavement industry.Furthermore,the study recommends employing and researching the enormous potential of using palm oil waste in the pavement sectors because they are more sustainable and have better performance.However,there are some barriers to using palm oil waste in the asphalt pavement industry,such as a lack of design standards and guidelines,inefficient raw material pro-cessing conversion facilities,and large-scale production equipment. | Nura Shehu Aliyu Yaro Muslich Hartadi Sutanto Noor Zainab Habib Madzlan Napiah Aliyu Usman Ahmad Hussaini Jagaba Abdulnaser M.Al-Sabaeei | 2022 | Journal of Road Engineering2022，2，4： | 1 |
| 7 | Examining the Influence of Telepresence on Spectator and Player Processing of Real and Fictitious Brands in a Computer Game 显示文摘 | NELSON M R YAROS R A KEUM H | 2006 | Journal of Advertising2006，35，1： | 1 |
| 8 | Protective action of L-camitine on cardiac Mitochondrial function and structure against fatty acid stress显示文摘 | Oyanagi E Yaro H Uchida MK | | 0，，01： | 1 |
| 9 | Musculoskeletal symptoms among dentists in relation to work pressure 显示文摘 | Ratzon NZ Yaros T Mizlik A | 2000 | WORK2000，15，3： | 1 |
| 10 | Chloroquine accumulates in breast-milk cells显示文摘 | Boelaert JR Yaro S Augustijns P | 2001 | AIDS2001，15，16： | 1 |
| 11 | American Spatial Development and the New Megalopolis显示文摘 | Carbonell Armando Yaro Robert | 2005 | Lincoln Institute of Land Policy Land Lines2005，17，2： | 1 |
| 12 | The epidemiology of Haemophilus influe-nzae type B meningitis in Burkina Faso显示文摘 | Yaro S Lourd M Naccro B | 2006 | Pediatr Infect Dis J2006，25，5： | 1 |
| 13 | Antiangiogenic radioimmunotherapy of human solid tumors in acid mice using 125I-labeled anti-endoglin monoclonal antibodies显示文摘 | Nasahito T Masso K Yaro H | 1999 | Journal of Cancer1999，82，5： | 1 |
| 14 | Free DNA in the serum of cancer patients and the effect of therapy显示文摘 | Leon S A Shapiro B Sklaroff D M Yaros M J | 1977 | Cancer Res1977，37，： | 1 |
| 15 | Musuloskeletal symptoms among dentists in relation to work pustare 显示文摘 | Ratzon NZ Yaros T Mizlik A | 2000 | WORK2000，15，3： | 1 |
| 16 | Sensorineural hearing loss in patients with chronic suppurative otitis media 显示文摘 | Kolo ES Salisu AD Yaro AM | 2012 | Indian J Otolar- yngol Head Neck Surg2012，64，1： | 1 |
| 17 | Musculoskeletal symptoms among dentists in relation to work posture显示文摘 | Ratzon NZ Yaros T Mizlik A | | 0，，03： | 1 |
| 18 | American Spatial Development and the New Megalopolis显示文摘 | Carbonell A Yaro R | 2005 | Land Lines2005，，16： | 1 |
| 19 | Collapse of optical pulse显示文摘 | Yaro Silberberg | 1990 | OPTICS LETTERS1990，15，22： | 1 |
| 20 | Differential expression of microRNAs in plasma of patients with laryngeal squamous cell carcinoma:potential early-detection markers for laryngeal squamous cell carcinoma显示文摘 | Ayaz L G rür A Yaro lu H Y | 2013 | J Cancer Res Clin Oncol2013，139，9： | 1 |
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