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| 1 | Behaviors of Oxide Layer at Interface between Semi-solid Filler Metal and Aluminum Matrix Composites during Vibration显示文摘The joint interface between semi-solid Zn-Al filler metal and SiCp/Al composites with applying vibration for different time was examined. With increasing vibrating time, the oxide layer was disrupted prior at the centre to the periphery of the interface. And the solid grains near the centre of interface in semi-solid filler metal aggregated into two solid regions and compressed the composites during vibration; the solid grains near the periphery of interface moved toward the edge and scraped the composites during vibration. The models of disrupting oxide layer under the vibration condition were developed. At the centre of interface, the oxide layer was tore and stripped during the solid grains in the semi-solid filler metal depressing the composites with a very high compressive stress. At the periphery of interface, the oxide layer was cut and stripped into the filler metal during the solid grains scraping the interface. | Lei Shi Jiuchun Yan Yanfei Han Bo Peng | 2011 | Journal of Materials Science & Technology2011，27，8： | 7 |
| 2 | Distinguishing transgenic from non-transgenic Arabidopsis plants by ~1H NMR-based metabolic fingerprinting显示文摘We have recently reported the construction of an nuclear magnetic resonance (NMR)-based metabonomics study platform, Automics. To examine the application of Automics in transgenic plants, we performed metabolic fingerprinting analysis, i.e., 1H NMR spectroscopy and multivariate analysis, on wild-type and transgenic Arabidopsis. We found that it was possible to distinguish wild-type from four transgenic plants by PLS-DA following application of orthogonal signal correction (OSC). Scores plot following OSC clearly demon-strates significant variation between the transgenic and non-transgenic groups, suggesting that the metabolic changes among wild-type and transgenic lines are possibly associated with transgenic event. We also found that the major contributing metabolites were some specific amino acids (i.e., threonine and alanine), which could correspond to the insertion of the selective marker BAR gene in the transgenic plants. Our data suggests that NMR-based metabonomics is an efficient method to distinguish fingerprinting difference between wild-type and transgenic plants, and can potentially be applied in the bio-safety assessment of transgenic plants. | Yanfei Ren Tao Wang Yufa Peng Bin Xia Li-Jia Qu | 2009 | Journal of Genetics and Genomics2009，36，10： | 7 |
| 3 | Hydrothermal synthesis of monodisperse α-Fe_2O_3 hexagonal platelets显示文摘Uniformly sized α-Fe2O3 hexagonal platelets were synthesized by a hydrothermal process using Fe(OH)3 suspension and large amount of NaOH.The reaction products were characterized by X-ray diffraction(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),selected area electron diffraction(SAED),and a vibrating sample magnetometer(VSM).The results show that the hexagonal platelets are fine,monodisperse and consisting of single-crystals.The magnetic hysteresis(M-H) curve of the samples measured at room temperature indicates that the α-Fe2O3 micro-platelets exhibit ferromagnetic behaviors with relatively low coercivity. | Dengfeng Peng Sadeh Beysen Qiang Li Yanfei Sun Linyu Yang | 2010 | Particuology2010，8，4： | 4 |
| 4 | An adaptive data-driven method for accurate prediction of remaining useful life of rolling bearings显示文摘 | Yanfeng PENG Junsheng CHENG Yanfei LIU Xuejun LI Zhihua PENG | 2018 | Frontiers of Mechanical Engineering2018，13，2： | 3 |
| 5 | Construction of Rat Model of Hepatic Fibrosis with Blood Stasis Syndrome Integrated with Traditional Chinese Medicine(TCM)Syndrome and Western Medicine Disease显示文摘[Objective]According to the theory of blood stasis in traditional Chinese medicine( TCM),the animal modeling method of hepatic fibrosis integrated with pathology and symptoms was explored and improved,to construct a new type of rat model of hepatic fibrosis with blood stasis syndrome integrated with traditional Chinese and western medicine. [Method]The hepatic fibrosis model of blood stasis with blood stasis syndrome was constructed by jointing multi factors,including intragastric administration of ethanol,high fat and low protein feeding,joint injection of dimethylnitrosamine( DMN),bovine serum albumin( BSA) and norepinephrine( NE). The modeling method was further compared with traditional CC14 single-factor modeling method from the aspects of mortality,blood stasis syndrome of TCM,syndrome grading,general morphology of liver pathology,liver function changes,as well as expression levels of three kinds of collagen( type I and type III collagen,α-SMA) determined by immunohistochemical staining method,and four items of rat hepatic fibrosis( HA,P3 NP,LN,CⅣ content) determined by radio enzyme immunoassay. [Result]In blood stasis group,(1) the mortality of rats was 20%;(2) model rats appeared typical blood stasis syndromes of TCM such as ecchymosis,dark purple tongue,loose stool,and blood stasis syndrome grading was high;(3) fibrosis changes of liver such as dark white surface,dense gray nodules and brittle texture were observed in general morphological examination;(4) serological liver function tests found that ALT and AST of model rats,as well as TBIL,DBIL and IBIL contents increased significantly;(5) immunohistochemical staining demonstrated that the expression levels of three kinds of collagen(type I and type III collagen,α-SMA) increased significantly;(6) four items of rat serum hepatic fibrosis,HA,P3 NP,LN,CⅣ content,increased significantly;(7) the above results in blood stasis syndrome model group(except morality and liver function) were higher than those in CC14 modeling group,and the difference was statistically significant( P < 0. 05). [Conclusion]The new improved modeling method effectively reduces high mortality in traditional CC14 modeling method.In addition to low mortality,the model animal has dual characteristics of disease in western medicine and syndrome in TCM. It is consistent with the pathological characteristics of hepatic fibrosis in western medicine when according with the basic characteristics of blood stasis syndrome in TCM. | Peng Yue Duan Xuelin Zhao Tiejian Yao Le Wei Yanfei Li Guiyu | 2017 | Animal Husbandry and Feed Science2017，9，2： | 3 |
| 6 | Effects of Aqueous Extract of Plumbago zeylanica L. in the Reversal of DMN-induced Hepatic Fibrosis in Rat显示文摘[Objectives] This study was conducted to evaluate the action of the aqueous extract of a medicinal plant Plumbago zeylanica L. in the reversal of dimethylnitrosamine( DMN)-induced hepatic fibrosis in rats,and to provide a scientific basis for the utilization of P. zeylanica in treatment of hepatic fibrosis. [Methods] Hepatic fibrosis in rats was induced by intraperitoneal injection of DMN. The rats were then given the aqueous extract of P. zeylanica at high,medium or low concentration by gavage for five weeks. Serum level of alanine aminotransferase( ALT) was determined by lactate dehydrogenase( LDH)-release assay,and serum level of aspartate transaminase( AST) was measured by UV-malate dehydrogenase( MDH) assay. Serum levels of total bilirubin( TBIL),direct bilirubin( DBIL)and indirect bilirubin( IBIL) were measured by vanadate oxidation assay. Four indices of hepatic fibrosis( hyaluronic acid,laminin,procollagen type Ⅲ and collagen type IV) were determined by radioimmunoassay( RIA) assay. Morphological damage of liver tissue was observed by hematoxylin-eosin staining( H&E staining). Immunohistochemical staining was performed to determine the location and area of deposited collagen type I,collagen type Ⅲ and α-smooth muscle actin( α-SMA) in liver tissue. [Results]Compared with the negative control( rats with diseased liver and untreated with P. zeylanica aqueous extract),the serum levels of ALT,AST,TBIL,DBIL and IBIL were significantly decreased by P. zeylanica aqueous extract; the levels of the four serum indices of hepatic fibrosis were also obviously reduced. H&E staining showed that hepatic fibrosis in rats was obviously inhibited or even reversed by P. zeylanica aqueous extract. Immunohistochemical staining proved that the aqueous extract of P. zeylanica significantly reduced the area and coloration of collagen type I,collagen type Ⅲ and α-SMA in rat liver. [Conclusions] The aqueous extract of P. zeylanica has a definite effect in reversal of DMN-induced hepatic fibrosis in rat by promoting the recovery of liver function,reversal of histopathological changes and reducing fibrotic collagen. | Yue PENG Xuelin DUAN Tiejian ZHAO Yanfei WEI Guiyu LI Lulu LIU | 2017 | Agricultural Biotechnology2017，6，3： | 3 |
| 7 | Uranium adsorption by dry and wet immobilized Saccharomyces cerevisiae显示文摘 | Xiaoliang Wang Guowen Peng Yan Yang Yanfei Wang Tingting He | 2012 | Journal of Radioanalytical and Nuclear Chemistry2012，，3： | 2 |
| 8 | A comparative proteomics approach to detect unintended effects in transgenic Arabidopsis显示文摘Recently, as part of biosafety assessments, unintended effects have been given much attention. In this study, we applied a proteomics approach to elucidate the unintended effects of random T-DNA insertion in transgenic plants. Separated proteins extracted from 12 transgenic Arabidopsis thaliana with different T-DNA insertion sites and from wild-type (ecotype Col-o) were analyzed. In the transgenic plants, 102 significantly altered protein spots were detected, in which 59 were up-regulated and 43 down-regulated. MALDI-TOF MS analysis showed that most of these expression level-altered proteins were involved in energy transfer, oxidative respiration and photosynthesis. However, none of these proteins was a toxic protein or allergen. Using plants with or without cold treatment, a natural environmental stress, as controls, we found that the number of the altered proteins was even less in those transgenic plants than those triggered by the cold treatment, suggesting that the transgenic events had a weaker impact on the plants than the environmental stresses. Interestingly, the phosphinothricin acetyl transferase (PAT), the BAR-encoded protein, was detected in nine out of twelve different T-DNA insertion lines at five different insertion sites. These data suggest that the most significant impact of transgenic events on the host plants is from the transgene itself, i.e., from the predictable intended effects, rather than unintended effects. This study also suggests that the proteomics approach has the potential to detect the unintended effects in transgenic plants. | Yanfei Ren Jun Lv Hua Wang Linchuan Li Yufa Peng Li-Jia Qu | 2009 | Journal of Genetics and Genomics2009，36，10： | 2 |
| 9 | Tumor microenvironment responsive drug delivery systems显示文摘Conventional tumor-targeted drug delivery systems(DDSs)face challenges,such as unsatisfied systemic circulation,low targeting efficiency,poor tumoral penetration,and uncontrolled drug release.Recently,tumor cellular molecules-triggered DDSs have aroused great interests in addressing such dilemmas.With the introduction of several additional functionalities,the properties of these smart DDSs including size,surface charge and ligand exposure can response to different tumor microenvironments for a more efficient tumor targeting,and eventually achieve desired drug release for an optimized therapeutic efficiency.This review highlights the recent research progresses on smart tumor environment responsive drug delivery systems for targeted drug delivery.Dynamic targeting strategies and functional moieties sensitive to a variety of tumor cellular stimuli,including pH,glutathione,adenosine-triphosphate,reactive oxygen species,enzyme and inflammatory factors are summarized.Special emphasis of this review is placed on their responsive mechanisms,drug loading models,drawbacks and merits.Several typical multi-stimuli responsive DDSs are listed.And the main challenges and potential future development are discussed. | Qunye He Jun Chen Jianhua Yan Shundong Cai Hongjie Xiong Yanfei Liu Dongming Peng Miao Mo Zhenbao Liu | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，4： | 2 |
| 10 | Minimizing Energy Cost for Green Data Center by Exploring Heterogeneous Energy Resource显示文摘With the deteriorating effects resulting from global warming in many areas, geographically distributed data centers contribute greatly to carbon emissions, because the major energy supply is fossil fuels. Considering this issue, many geographically distributed data centers are attempting to use clean energy as their energy supply, such as fuel cells and renewable energy sources. However, not all workloads can be powered by a single power sources, since different workloads exhibit different characteristics. In this paper, we propose a fine-grained heterogeneous power distribution model with an objective of minimizing the total energy costs and the sum of the energy gap generated by the geographically distributed data centers powered by multiple types of energy resources. In order to achieve these two goals, we design a two-stage online algorithm to leverage the power supply of each energy source. In each time slot, we also consider a chance-constraint problem and use the Bernstein approximation to solve the problem. Finally, simulation results based on real-world traces illustrate that the proposed algorithm can achieve satisfactory performance. | Xiaoxuan Hu Peng Li Yanfei Sun | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，1： | 2 |
| 11 | Synthesis, Characterization and Hydrolysis of an Aliphatic Polycarbonate by Terpolymerization of Carbon Dioxide, Propylene Oxide and Maleic Anhydride显示文摘 | Liu Yanfei Huang Kelong Peng Dongming | 2006 | Polymer2006，47，： | 1 |
| 12 | Remote plasma-enhanced atomic layer deposition of gallium oxide thin films with NH_3 plasma pretreatment显示文摘High quality gallium oxide(Ga_2O_3) thin films are deposited by remote plasma-enhanced atomic layer deposition(RPEALD) with trimethylgallium(TMG) and oxygen plasma as precursors. By introducing in-situ NH3 plasma pretreatment on the substrates, the deposition rate of Ga_2O_3 films on Si and GaN are remarkably enhanced, reached to 0.53 and 0.46 ?/cycle at 250 °C,respectively. The increasing of deposition rate is attributed to more hydroxyls(–OH) generated on the substrate surfaces after NH3 pretreatment, which has no effect on the stoichiometry and surface morphology of the oxide films, but only modifies the surface states of substrates by enhancing reactive site density. Ga_2O_3 film deposited on GaN wafer is crystallized at 250 °C, with an epitaxial interface between Ga_2O_3 and GaN clearly observed. This is potentially very important for reducing the interface state density through high quality passivation. | Hui Hao Xiao Chen Zhengcheng Li Yang Shen Hu Wang Yanfei Zhao Rong Huang Tong Liu Jian Liang Yuxin An Qing Peng Sunan Ding | 2019 | Journal of Semiconductors2019，40，1： | 1 |
| 13 | Structure and anti- tumor activities of the water-soluble polysaccharides from Gano- derma tsugae mycelium 显示文摘 | Peng Yanfei Zhang Lina Zeng Fanbo | 2005 | Carbohydrate Polymers2005，59，3： | 1 |
| 14 | Proslaglandin E2 in- duces stromal celt derived factor - 1 expression in pnstate stromal cells by activating protein kinase a and transcription factor Spl 显示文摘 | Peng Yanfei Shi Jiandang Du Xiaoling | 2013 | The International Journal of Biochemistry & Cell Biology2013，45，3： | 1 |
| 15 | Prostaglandin E2 in- duces stromal cell - derived factor - 1 expression in prostate stromal cells by activating protein kinase A and transcription factor Spl 显示文摘 | Peng Yanfei Shi Jiandang Du Xiaoling | 2013 | The International Journal of Biochemistry & Cell Biology2013，45，3： | 1 |
| 16 | Synthesis, characterization and hydrolysis of an aliphatic polycarbonate by terpolymedzation of carbon dioxide, propylene oxide and maleie anhydride显示文摘 | LIU Yanfei HUANG Kelong PENG Dongming | 2006 | Polymer2006，47，26： | 1 |
| 17 | Structure and antitumor activities of the water-soluble polysaccharides from Ganoderma tsugae mycelium显示文摘 | PENG Yanfei ZHANG Lina ZENG Fanbo | 2005 | Carbohydrate Polymers2005，59，3： | 1 |
| 18 | Preparation and antimierobial activity of hydroxypropyl chitosan 显示文摘 | PENG Yanfei HAN Baoqin LIU Wanshun | 2005 | Carbohydrate Research2005，340，11： | 1 |
| 19 | Preparation of carbon dioxide/propylene oxide/s-eaprolactone copolymers and their drug release behaviors显示文摘 | PENG Dongming HUANG Kelong LIU Yanfei | 2007 | Polymer Bulletin2007，59，： | 1 |
| 20 | Preparation of poly(butylene-eo-e-caprolaetone carbonate) and their use as drug carriers for a controlled delivery显示文摘 | LIU Yanfei HUANG Kelong PENG Dongming | 2007 | Journal of Polymer Science Part A: Polymer Chemistry2007，45，11： | 1 |
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