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| 1 | Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a mouse model of Alzheimer’s disease显示文摘Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural plasticity and improve cognitive impairment.The purpose of this study was to investigate the effects of mesenchymal stem cell-derived exosomes on neurogenesis and cognitive capacity in a mouse model of Alzheimer’s disease.Alzheimer’s disease mouse models were established by injection of beta amyloid 1?42 aggregates into dentate gyrus bilaterally.Morris water maze and novel object recognition tests were performed to evaluate mouse cognitive deficits at 14 and 28 days after administration.Afterwards,neurogenesis in the subventricular zone was determined by immunofluorescence using doublecortin and PSA-NCAM antibodies.Results showed that mesenchymal stem cells-derived exosomes stimulated neurogenesis in the subventricular zone and alleviated beta amyloid 1?42-induced cognitive impairment,and these effects are similar to those shown in the mesenchymal stem cells.These findings provide evidence to validate the possibility of developing cell-free therapeutic strategies for Alzheimer’s disease.All procedures and experiments were approved by Institutional Animal Care and Use Committee(CICUAL)(approval No.CICUAL 2016-011)on April 25,2016. | Edwin E. Reza-Zaldivar Mercedes A. Hernández-Sapiéns Yanet K. Gutiérrez-Mercado Sergio Sandoval-ávila Ulises Gomez-Pinedo Ana L. Márquez-Aguirre Estefanía Vázquez-Méndez Eduardo Padilla-Camberos Alejandro A. Canales-Aguirre | 2019 | Neural Regeneration Research2019，14，9： | 19 |
| 2 | Thermal condensation of phthalimide with malonic acid显示文摘 | Kopranenkov V N Makarova E A Luk'yanets E A | 1988 | Chem Heterocyclic Compd1988，24，4： | 1 |
| 3 | Tertbutyl derivatives of porphyrazine 显示文摘 | Goncharova S L Luk yanet E A | 1997 | Zh Obshch Khim1997，47，： | 1 |
| 4 | Im- proved method for preparing zinc meso-tetraphenyl-tet- rabenzoporphine 显示文摘 | Luk'yanets E A Dashkevieh S N Kobayashi N | 1993 | Russ J C en Chem1993，63，6： | 1 |
| 5 | Development and validation of a novel method to derive central aortic systolic pressure from the radial pressure wave form using an N-point moving average method显示文摘 | Williams B Lacy PS Yanet | 2011 | Jam Coll Cardiol2011，，8： | 1 |
| 6 | New Reagents for Determination of the Quantum Efficiency of Singlet Oxygen Generation in Aqueous Media显示文摘 | N. A. Kuznetsova N. S. Gretsova O. A. Yuzhakova V. M. Negrimovskii O. L. Kaliya E. A. Luk’yanets | 2001 | Russian Journal of General Chemistry2001，，1： | 1 |
| 7 | Status of hydrothermal growth of bulk ZnO:latest issues and advantages显示文摘 | Dem'yanets L N Lyutin V I | | 0，，5： | 1 |
| 8 | Status of Hydrothermal Growth of Bulk Zn O:Latest Issues and Advantages显示文摘 | Dem'yanets L N Lyutin V I | 2008 | Journal of Crystal Growth2008，310，： | 1 |
| 9 | Synthesis of sulfonated 1,2-dicyanobenzenes显示文摘 | Negrimovsky V M Derkacheva V M Luk'Yanets E A | 1995 | Phosphorus Sulfur and Silicon and the Related Elements1995，104，： | 1 |
| 10 | Increased vascular permea- bility in the circumventricular organs of adult rat brain due to stimulation by extremely low frequency magnetic fields显示文摘 | Yanet K G M Luis C D Ulises G P | 2013 | Bioelec- tromagnetics2013，34，2： | 1 |
| 11 | Lipoprotein NMB0928 from Neisseria meningitidis serogroup B as a novel vaccine candidate显示文摘 | Maité Delgado Daniel Yero Olivia Niebla Sonia González Yanet Climent Yusleydis Pérez Karem Cobas Evelín Caballero Darien García Rolando Pajón | 2007 | Vaccine2007，，50： | 1 |
| 12 | Zinc oxide:hydrothermal growth of nano-and bulk crystals and their luminescent properties显示文摘 | DEM'YANETS L N LI L E UVAROVA T G | 2006 | J Mater2006，41，： | 1 |
| 13 | Hydrothermal synthesis and spectroscopic properties of crystalline ZnO powders and films显示文摘 | DEM YANETS L N LI L E UVAROVA T G | 2004 | Inorganic Materials2004，40，11： | 1 |
| 14 | Thermal condensation of phthalimide with malonic acid显示文摘 | Kopranenkov V N Makarova E A Luk'yanets E A | 1988 | Chemistry of Heterocyclic Compounds1988，24，4： | 1 |
| 15 | Tert - butyl derivatives of porphyrazine 显示文摘 | KOPRANENKOV V N GONCHAROVA S L LUK YANET E A | 1997 | Zh Obshch Khim1997，47，： | 1 |
| 16 | Early Gametogenesis of Kumamoto oyster ( Crassostrea sikamea ) 显示文摘 | Jorge C M Rebeca V Y Yanet GR | 2012 | Hidrobiologica2012，22，2： | 1 |
| 17 | Productive Response of Brassica rapa L.subsp.chinensis to Application of VIUSID Agro显示文摘In order to evaluate the effect of VIUSID agro on the yield response of a pak choi harvest,a randomised block experiment was designed with four treatments and three replications.The treatments were dosages of 0.1,0.2 and 0.3 L/ha and one control.The number of leaves per plant and the fresh and dry mass of the plant were measured.In addition,growth indexes were evaluated,such as relative growth rate,active growth rate,harvest index and agricultural yield.The number of leaves per plant was significantly greater at 35 days after sowing(das)for 0.2 L/ha and 0.3 L/ha treatments,with increases of 15.0%and 14.17%relative to the control.Regarding plant length and fresh mass at the final evaluation,the treatments using higher dosages produced the best results.Regarding the active growth rate,the 0.2 L/ha dosage produced the best effects,and regarding relative growth rate,the 0.2 L/ha and 0.3 L/ha dosages produced the best results relative to the control.The harvest index did not benefit from the used dosages,while a higher agricultural yield was achieved using the 0.2 L/ha and 0.3 L/ha dosages at 18.03%and 12.88%compared to the control.Therefore,VIUSID agro positively influenced the yield behaviour of pak choi. | Kolima Pena Calzada Dilier Olivera Viciedo Alexander Calero Juan Carlos Rodríguez Bulent Kukurtcu Yanet Milagros Placenciaálvarez Alexei Castro Salas | 2019 | Journal of Agricultural Science and Technology(B)2019，9，2： | 0 |
| 18 | An egg-shell bifunctional CeO_(2)-modified NiPd/Al_(2) O_(3) catalyst for petrochemical processes involving selective hydrogenation and hydroisomerization显示文摘The catalytic performance during the 1-butyne hydrogenation using two reduced Al_(2) O_(3)-supported Pdbased catalysts was carried out in a total recirculation system with an external fixed-bed reactor.The lab-prepared egg-shell NiPd/CeO_(2)-Al_(2) O_(3) catalyst(NiPdCe) with Pd loading=0.5 wt%,Ni/Pd atomic ratio=1 and CeO_(2) loading=3 wt% was synthesized and characterized,and it was compared with an egg-shell Al_(2) O_(3)-supported Pd based commercial catalyst(PdCC).The reduced catalysts were characterized by X-ray diffraction,X-ray photoelectron spectroscopy,and high-resolution transmission electron microscopy.The textural characteristics and ammonia temperature-programmed desorption profiles of the fresh(unreduced) catalysts were also obtained.Both catalysts show high 1-butyne conversion and selectivity to 1-butene,but the catalysts also present important differences between hydroisomerizing and hydrogenating capabilities.NiPdCe catalyst shows higher capability for hydroisomerization reactions,while the PdCC catalyst exhibits higher hydrogenating capability.The observed catalytic performances can be interesting for some industrial processes and can provide a guideline for the development of a Pd-based catalyst with specific catalytic properties. | Franklin J.Mendez Javier A.Alves Yahse Rojas-Challa Oscar Corona Yanet Villasana Julia Guerra German Garcia-Colli Osvaldo M.Martinez Joaquin L.Brito | 2021 | Journal of Rare Earths2021，39，11： | 0 |
| 19 | Arsenic and chromium resistance mechanisms in the Micrococcus luteus group显示文摘High arsenic(As)and chromium(Cr)concentrations are currently receiving attention because of their negative effects on the environment and human health.Microorganisms inhabiting contaminated environments have developed resistance mechanisms against the toxicity of these pollutants.Indeed,members of the bacterial genus Micrococcus have been isolated from different toxic metal-contaminated environments;however,knowledge concerning its resistance mechanisms to As and Cr toxicity remains limited.Micrococcus luteus strains(An24,Mh,NE2TL6,and NE2TTS4)were isolated from the endosphere and soil of two heavy metal-contaminated sites in Mexico to identify differences in the resistance mechanisms by the M.luteus group.The strains were resistant to As(As^(3+)and As^(5+)),chromate,dichromate,cobalt,copper,nickel,and zinc.Genome analysis indicated that the heavy metal-resistant strains(An24,Mh,NE2TL6,and NE2TTS4)could be assigned to the M.luteus group and had more heavy metal-resistant genes(transporters,chaperones,and enzymes)compared to reference strains of the M.luteus group,M.luteus NCTC 2665^(T)and Micrococcus endophyticus JCM 16951^(T).The resistant bacteria were able to biotransform As^(3+)and As^(5+)through a carbon source-dependent mechanism.The biotransformation of As5+was potentially carried out in the cytoplasm through a thioredoxin-dependent pathway,which may be coupled with biosorption.A qualitative analysis of organic acids(OAs)identified a change in the OA profile of the metal-resistant strains that was As-or Cr-dependent.Our genomic and phenotypic findings suggest that the four M.luteus group strains evaluated in the current study have developed resistance mechanisms that may enable their survival in contaminated sites. | Ivan ARROYO-HERRERA Brenda ROMÁN-PONCE Rafael BUSTAMANTE-BRITO Joseph GUEVARA-LUNA Erika Yanet TAPIA-GARCÍA Violeta LARIOS-SERRATO Nannan ZHANG Paulina ESTRADA-DE LOS SANTOS En Tao WANG María Soledad VÁSQUEZ-MURRIETA | 2023 | Pedosphere2023，33，4： | 0 |
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