|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | RMB Internationalization and Its Implications for Financial and Monetary Cooperation in East Asia显示文摘这份报纸强调作为国际货币的一个长期的决定因素开发票的金融财产而非贸易的命名的重要性。中国需要将放宽并且打开它的金融系统并且使 RMB 充分可改变,并且采用一个更灵活的汇率系统加快它的货币国际化,中国也能为跟随一条全球或地区性的途径。因为它将要求是可能的在中国在来十年的机构的能力以外的金融自由化的一个范围和 timeframe,全球途径是更危险、更无法预言的策略。有二种选择,能在跟随地区性的途径被拿。一个人正在创造 ASEAN+New 3 (中国大陆,香港,和台湾) RMB 团体和其它正在放宽中国是金融工业并且由在 ASEAN+3 的框架以内在东亚的经济集成起主要作用使 RMB 国际化。这份报纸断定后者是为中国的一条更现实主义、有效的途径。 | Yung Ckul Park | 2010 | China & World Economy2010，18，2： | 35 |
| 2 | Three-dimensional endoanal ultrasonographic assessment of an anal fistula with and without H_2O_2 enhancement显示文摘AIM:To evaluate the effectiveness of three-dimensional endoanal ultrasound (3D-EAUS) in the assessment of anal fistulae with and without H2O2 enhancement.METHODS: Sixty-one patients (37 males, aged 17-74 years) with anal fi stulae, which were not simple low types, were evaluated by physical examination and 3D-EAUS with and without enhancement. Fistula classification was determined with each modality and compared to operative findings as the reference standard.RESULTS: The accuracy of 3D-EAUS was significantly higher than that of physical examination in detecting the primary tract (84.4% vs 68.7%, P=0.037) and secondary extension (81.8% vs 62.1%, P=0.01) and localizing the internal opening (84.2% vs 59.7%, P=0.004). A contrast study with H2O2 detected several more fistula components including two primary suprasphincteric fistula tracks and one supralevator secondary extension, which were not detected on non-contrast study. However, there was no significant difference in accuracy between 3D-EAUS and H2O2-enhanced 3D-EAUS with respect to classification of the primary tract (84.4% vs 89.1%, P=0.435) or secondary extension (81.8% vs 86.4%, P=0.435) or localization of the internal opening (84.2% vs 89.5%, P=0.406).CONCLUSION: 3D-EAUS was highly reliable in the diagnosis of an anal fistula. H2O2 enhancement was helpful at times and selective use in diffi cult cases may be economical and reliable. | Yung Kim Young Jin Park | 2009 | World Journal of Gastroenterology2009，15，38： | 23 |
| 3 | Facile design of Au@Pt core-shell nanostructures: Formation of Pt submonolayers with tunable coverage and their applications in electrocatalysis显示文摘 | Fulin Zheng Wing-Tak Wong Ka-Fu Yung | 2014 | Nano Research2014，7，3： | 17 |
| 4 | 氨基酸腹膜透析液与传统腹膜透析液对腹膜间皮细胞功能的影响显示文摘目的通过体外实验对照观察了含氨基酸腹膜透析液(1.1%Nutrineal)和传统葡萄糖腹膜透析液(1.5%Dianeal)对正常人腹膜间皮细胞(HPMC)的生物相容性及功能的影响。方法用1.1%Nutrineal和1.5%Dianeal进行腹膜透析,4h后引流。观察两种不同透出液及不同时间对体外培养的HPMC功能的影响。采用四甲基偶氮多胍(MTT)和细胞直接计数法测定HPMC增殖程度,以测定乳酸脱氢酶(LDH)水平显示细胞损伤程度。采用ELISA法测定白细胞介素6(IL-6)水平。结果与5%葡萄糖对照组相比,1.5%Dianeal透出液可显著降低HPMC细胞增殖能力、细胞总蛋白合成、IL-6分泌水平和细胞黏附能力(P<0.001、P<0.001、P<0.0001、P<0.0001),而细胞培养液上清中的LDH分泌水平明显提高(P<0.001)。1.1%Nutrineal透出液可降低HPMC细胞增殖能力(P<0.001)和明显增加IL-6的分泌水平(P<0.0001),但对HPMC的LDH分泌水平,细胞黏附能力,蛋白总合成量无明显影响。结论与传统的葡萄糖腹膜透析液相比,氨基酸腹膜透析液能更好地维持HPMC在细胞存活能力、细胞黏附功能及蛋白合成等方面的功能。氨基酸腹膜透析液可诱导HPMC分泌IL-6水平显著升高,其机制有待进一步探讨。 | 孙玉玲 Susan Yung 余学清 梁国雄 曾志伟 陈德瑁 | 2004 | 中华肾脏病杂志2004，20，1： | 15 |
| 5 | Prospective validation of %p2PSA and the Prostate Health Index, in prostate cancer detection in initial prostate biopsies of Asian men, with total PSA 4-10 ng ml-1显示文摘尽管有它为屏蔽的前列腺癌症的普遍使用,低特性使 PSA 成为非最优的 biomarker,特别在 4-10 ng ml 1 的诊断灰色的地区。假积极与伴随的病态导致不必要的活体检视。这在与在 4.0 和 10 ng ml 1 之间的全部的 PSA 介绍的亚洲人是 % p2PSA 和前列腺健康索引(PHI ) 的第一未来的确认研究。我们学习了在 50 和 75 岁之间的 157 个亚洲人,与每直肠的前列腺考试的正常,经历他们的第一前列腺活体检视,用一个标准化活体检视协议,为 4-10 ng ml 1 的 PSA 层次。(19.1%) 三十被发现在活体检视上有前列腺癌症。有或没有前列腺癌症的病人之间的统计上重要的差别被作出对有利的裁决全部的 PSA, p2PSA, % p2PSA,和 PHI。在为全部的 PSA, % fPSA, % p2PSA,和 PHI 操作典型曲线的接收装置的曲线下面的区域分别地是 0.479, 0.420, 0.695,和 0.794。PHI 最好预言 prostatic 活体检视结果。在 90% 的敏感, PHI 的特性(95% CI ) 是 58.3% ,多于在 17.3% 点使全部的 PSA 的特性增加两倍,潜在地避免 77 (49%) 不必要的活体检视。类似于研究在主要白种人人口,我们有希望地证明了 % p2PSA 和 PHI 极大地超过总数并且释放总计 PSA 比率,在前列腺癌症的察觉起初活体检视。更高的 PHI 层次也对应于增加检测 GS 7 癌症的风险。我们验证了 PHI 的使用与在 4 和 10 ng ml 1 之间的浆液 PSA 在亚洲人关于前列腺活体检视帮助决策。 | Lincoln GL Tan Yung Khan Tan Bee Choo Tai Karen ML Tan Vineet Gauhar Ho Yee Tiong Robert CW Hawkins Thomas P Thamboo Felicia SK Hong Edmund Chiong | 2017 | Asian Journal of Andrology2017，19，3： | 13 |
| 6 | m^6A-dependent biogenesis of circular RNAs in male germ cells显示文摘The majority of circular RNAs(circRNAs)spliced from coding genes contain open reading frames(ORFs)and thus,have protein coding potential.However,it remains unknown what regulates the biogenesis of these ORF-containing circRNAs,whether they are actually translated into proteins and what functions they play in specific physiological contexts.Here,we report that a large number of circRNAs are synthesized with increasing abundance when late pachytene spermatocytes develop into round and then elongating spermatids during murine spermatogenesis.For a subset of circRNAs,the back splicing appears to occur mostly at m^6A-enriched sites,which are usually located around the start and stop codons in linear mRNAs.Consequently,approximately a half of these male germ cell circRNAs contain large ORFs with m^6A-modified start codons in their junctions,features that have been recently shown to be associated with protein-coding potential.Hundreds of peptides encoded by the junction sequences of these circRNAs were detected using liquid chromatography coupled with mass spectrometry,suggesting that these circRNAs can indeed be translated into proteins in both developing(spermatocytes and spermatids)and mature(spermatozoa)male germ cells.The present study discovered not only a novel role of m^6A in the biogenesis of coding circRNAs,but also a potential mechanism to ensure stable and long-lasting protein production in the absence of linear mRNAs,i.e.,through production of circRNAs containing large ORFs and m^6A-modified start codons in junction sequences. | Chong Tang Yeming Xie Tian Yu Na Liu Zhuqing Wang Rebekah J.Woolsey Yunge Tang Xinzong Zhang Weibing Qin Ying Zhang Ge Song Weiwei Zheng Juan Wang Weitian Chen Xiongyi Wei Zhe Xie Rachel Klukovich Huili Zheng David R.Quilici Wei Yan | 2020 | Cell Research2020，30，3： | 12 |
| 7 | 单产品物流网络系统的联合决策模型显示文摘考虑全球制造环境下单产品在多个供应商和多个用户之间的联合物流决策问题,包括供应商指定的生产任务、生产批量、供应商和用户之间的年运输量和订货批量.联合决策过程可以看作是两层决策,其中第一层是供应商指定的生产任务和生产批量的联合决策(APLS),第二层是运输和订货批量的联合决策(TOQ).因此,提出了基于两层分解的启发式算法来求解这样的联合决策模型(JDM).结合实际例子对模型和算法进行了仿真分析,结果证明了基于两层分解的启发式算法的有效性. | 唐加福 Yung Kai-leung 刘士新 | 2005 | 管理科学学报2005，8，2： | 11 |
| 8 | Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia显示文摘Aim:Pro-inflammatory mediators,such as prostaglandin E_2 (PGE_2) and nitric oxide(NO),and pro-inflammatory cytokines such as interleukin (IL)-1β,IL-6,and TNF-α,play pivotal roles in brain injuries.The anti-inflammatory properties are knownto be associated with significant reductions in pro-inflammatory mediators in braininjuries.In the present study we investigate whether the effects of curcumin onthe production of pro-inflammatory mediators in lipopolysaccharide (LPS)-stimu-lated BV2 microglia.Methods:Curcumin were administered and their effects onLPS-induced pro-inflammatory mediators were monitored by Western blottingand RT-PCR.Result:Curcumin significantly inhibited the release of NO,PGE_2,and pro-inflammatory cytokines in a dose-dependent manner.Curcumin alsoattenuated the expressions of inducible NO synthase and cyclooxygenase-2 mRNAand protein levels.Moreover,curcumin suppressed NF-kB activation via thetranslocation of p65 into the nucleus.Our data also indicate that curcumin exertsanti-inflammatory properties by suppressing the transcription of proinflammatorycytokine genes through the NF-kB signaling pathway.Conclusion:Anti-inflam-matory properties of curcumin may be useful for treating the inflammatory anddeleterious effects of microglial activation in response to LPS stimulation. | Cheng-yun JIN Jae-dong LEE Cheol PARK Yung hyun CHOI Gi-young KIM | 2007 | Acta Pharmacologica Sinica2007，28，10： | 10 |
| 9 | Interactions Between Arbuscular Mycorrhizae and Plants in Phytoremediation of Metal-Contaminated Soils: A Review显示文摘Metal contamination in the environment is a global concern due to its high toxicity to living organisms and its worldwide distribution.The principal goal of this review is to examine the current strategies and technologies for the remediation of metalcontaminated soils by metal-accumulating plants and assess the roles of arbuscular mycorrhizal(AM)fungi in remediation of soils under hyperaccumulator or non-accumulator plants.The use of plants to remove metals from the environment or reduce the toxicity,known as phytoremediation,is an environmentally sustainable and low cost remediation technology.The mechanisms of the use of hyperaccumulator plants for phytoremediation included solubilization of the metal in the soil matrix,the plant uptake of the metal,detoxification/chelation and sequestration,and volatilization.Recently,some ecologists have found that phytoremediation with the aids of mycorrhizae can enhance efciency in the removal of toxic metals.AM fungi can facilitate the survival of their host plants growing on metal-contaminated land by enhancing their nutrient acquisition,protecting them from the metal toxicity,absorbing metals,and also enhancing phytostabilization and phytoextraction.Such information may be useful for developing phytoremediation program at metal-contaminated sites. | LEUNG Ho-Man WANG Zhen-Wen YE Zhi-Hong YUNG Kin-Lam PENG Xiao-Ling CHEUNG Kwai-Chung | 2013 | Pedosphere2013，23，5： | 10 |
| 10 | 计算机辅助药物靶标搜寻在探索中草药有效成分机制方面的应用显示文摘应用INVDOCK软件进行计算机搜寻药物靶标。研究结果显示该软件具有实际应用潜力及在普及型计算机上可进行运算的可行性。此方法除用于研究药物或先导化合物的未知医疗靶标及毒副作用靶标外 ,亦可用来研究中草药的作用机理。本研究应用INVDOCK寻找数个中草药有效成分的医疗作用靶标并同已知实验结果进行比较。结果表明INVDOCK可作为探索中草药机理的有效辅助工具。 | 陈宇综 Ung Chong Yung | 2001 | 中国药物化学杂志2001，11，3： | 10 |
| 11 | Multi-microgrid Energy Management Systems: Architecture, Communication, and Scheduling Strategies显示文摘The increasing penetration of various distributed and renewable energy resources at the consumption premises,along with the advanced metering,control and communication technologies,promotes a transition on the structure of traditional distribution systems towards cyber-physical multi-microgrids(MMGs).The networked MMG system is an interconnected cluster of distributed generators,energy storage as well as controllable loads in a distribution system.And its operation complexity can be decomposed to decrease the burdens of communi-cation and control with a decentralized framework.Consequently,the multi-microgrid energy management system(MIVIGEIV1S)plays a significant role in improving energy efficiency,power quality and reliability of distribution systems,especially in enhancing system resiliency during contingencies.A comprehensive overview on typical functionalities and architectures of MMGEMS is illustrated.Then,the emerging communication technologies for information monitoring and interaction among MMG clusters are surveyed.Furthermore,various energy scheduling and control strategies of MMGs for interactive energy trading,multi-energy management,and resilient operations are thoroughly analyzed and investigated.Lastly,some challenges with great importance in the future research are presented. | Bin Zhou Jianting Zou Chi Yung Chung Huaizhi Wang Nian Liu Nikolai Voropai Daosen Xu | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，3： | 8 |
| 12 | Interactions between wind and water erosion change sediment yield and particle distribution under simulated conditions显示文摘Wind and water erosion are among the most important causes of soil loss, and understanding their interactions is important for estimating soil quality and environmental impacts in regions where both types of erosion occur. We used a wind tunnel and simulated rainfall to study sediment yield, particle-size distribution and the fractal dimension of the sediment particles under wind and water erosion. The experiment was conducted with wind erosion firstly and water erosion thereafter, under three wind speeds(0, 11 and 14 m/s) and three rainfall intensities(60, 80 and 100 mm/h). The results showed that the sediment yield was positively correlated with wind speed and rainfall intensity(P<0.01). Wind erosion exacerbated water erosion and increased sediment yield by 7.25%–38.97% relative to the absence of wind erosion. Wind erosion changed the sediment particle distribution by influencing the micro-topography of the sloping land surface. The clay, silt and sand contents of eroded sediment were also positively correlated with wind speed and rainfall intensity(P<0.01). Wind erosion increased clay and silt contents by 0.35%–19.60% and 5.80%–21.10%, respectively, and decreased sand content by 2.40%–8.33%, relative to the absence of wind erosion. The effect of wind erosion on sediment particles became weaker with increasing rainfall intensities, which was consistent with the variation in sediment yield. However, particle-size distribution was not closely correlated with sediment yield(P>0.05). The fractal dimension of the sediment particles was significantly different under different intensities of water erosion(P<0.05), but no significant difference was found under wind and water erosion. The findings reported in this study implicated that both water and wind erosion should be controlled to reduce their intensifying effects, and the controlling of wind erosion could significantly reduce water erosion in this wind-water erosion crisscross region. | TUO Dengfeng XU Mingxiang ZHAO Yunge GAO Liqian | 2015 | Journal of Arid Land2015，7，5： | 8 |
| 13 | 儿童重症监护中血糖控制与器官功能衰竭和病死率的关系显示文摘目的研究机械通气患几发生高血糖与器官功能衰竭的关系;介绍澳大利亚和新西兰PICU控制血糖的方法与实践。设计前瞻性队列研究。场所澳大利亚和新西兰的全部9家专业PICU病房。对象机械通气〉12h的患儿,但除外以下情况:合并糖尿病酮症酸中毒;家庭机械通气;入院时经积极心肺复苏;签有“不予复苏”医嘱。干预无。测量指标和主要结果所有患儿的血糖最长监测时间为14d,用临床和实验室指标计算儿童logistic器官功能障碍评分(PELOD)。研究中共有409例患儿使用了胰岛素。50%的患儿血糖值〉6.1mmol/L,同时89%患儿的血糖峰值〉6.1mmol/L,达到峰值的时间中位数是7h。在血糖-时间曲线上,采样时间中位数对应的曲线下面积〉6.1mmol/睹被定义为高血糖。高血糖患儿病死率为13%,而无高血糖者病死率为3%。高血糖和高PELOD(≥10)呈独立相关(OR值为3.41,95%CI:1.91~6.10)。高血糖与病死率也呈独立相关(OR值为3.31,95%CI:1.26~7.70)。早期高血糖(最初48h内)与上述预后亦相关,但与1d后PELOD加重和2d后PELOD≥10无关。5%的息儿接受了胰岛素治疗。结论高血糖在PICU较常见,通常出现较早,并与器官功能衰竭和死亡呈独立相关。但早期高血糖与晚发或加重的器官功能衰竭无关。澳大利亚和新西兰的PICU很少使用胰岛素。 | Yung M Wilkins B Slater A | 2008 | 中国小儿急救医学2008，15，2： | 8 |
| 14 | 胶质瘤干细胞对替莫唑胺敏感性的研究显示文摘目的探讨胶质瘤干细胞(GSC)对替莫唑胺(TMZ)的敏感性及耐药机制。方法新鲜多形性胶质母细胞瘤(GBM)标本培养后获得GSC。免疫荧光技术检测未分化GSC的CD133及分化生长GSC的GFAP的表达,MTS法检测对替莫唑胺的敏感性,流式细胞技术对CD133阳性细胞的比例进行定量,荧光标记的甲基化特异性PCR分析MGMT启动子区域的甲基化状态,Western blot检测抑癌基因PTEN的表达。结果(1)5例GBM标本中成功获得GSC,符合肿瘤干细胞定义。(2)5个GSC细胞株多数对TMZ不敏感。其中,T509的半数抑制浓度(IC50)为22.3μmol/L(敏感),T411的IC50为286.3μmol/L(中度敏感),其余3个细胞株T402,T405及T509的IC50皆大于1000μmol/L(不敏感)。(3)CD133阳性细胞比例大于10%的GSC细胞株对TMZ不敏感。(4)MGMT启动子区域呈去甲基化状态的GSC对TMZ不敏感或仅为中度敏感。(5)5个GSC细胞株中,PTEN表达水平差异大,与GSC对TMZ的敏感性无明显关联。结论GSC对TMZ普遍耐药,与MGMT启动子区域甲基化状态及CD133阳性细胞有关,而与PTEN蛋白表达水平无明显关联。 | 赛克 WANG Shu-zhen Popoff S Yung WK Colman H 陈忠平 | 2009 | 中华神经外科杂志2009，25，10： | 7 |
| 15 | Association of nucleophosmin/B23 with bladder cancer recurrence based on immunohistochemical assessment in clinical samples显示文摘目的: 与膀胱癌 recurrence.Methods 调查 nucleophosmin/B23 表示的可能的关联: 将切除得通过手术的膀胱肿瘤上演了磅 a 到 pT4 被学习组织的 immunohistochemistry.The 为 nucleophosmin/B23 表示检验由通过手术在 Chang Gung 对待的 132 个连续病人组成了在 1998 年 12 月和 1999 年 11 月之间的纪念物医院。平均数列在后面在上面是 72 个月(range:48-84 月).Results : 染色的原子 nucleophosmin/B23 在 96% 晚期和糟糕区分的肿瘤被检测。更高的 nucleophosmin/B23 层次被连接到复发的更先进的肿瘤阶段,等级,差的预后,和可能性(P < 0.05 ) 。艇长多,变量分析为肿瘤作为独立指示物显示了 nucleophosmrn/B23 表示复发(P=0.009 ).Conclusion : 结果建议 nucleophosmin/B23 是有利预示的指示物因为膀胱 cancer.Nucleophosmin/B23 能是为预言膀胱癌症的一个有用分子的肿瘤标记复发。 | Ke-hung TSUI Homg-heng JUANG Tsong-hai LEE Phei-lang CHANG Chien-lun CHEN Benjamin Yat-ming YUNG | 2008 | Acta Pharmacologica Sinica2008，29，3： | 7 |
| 16 | Current and future molecular diagnostics in colorectal cancer and colorectal adenoma显示文摘Colorectal cancer(CRC)is one of the most prevalent cancers in developed countries.On the other hand,CRC is also one of the most curable cancers if it is detected in early stages through regular colonoscopy or sigmoidoscopy.Since CRC develops slowly from precancerous lesions,early detection can reduce both the incidence and mortality of the disease.Fecal occult blood test is a widely used non-invasive screening tool for CRC.Although fecal occult blood test is simple and cost-effective in screening CRC,there is room for improvement in terms of the accuracy of the test.Genetic dysregulations have been found to play an important role in CRC development.With better understanding of the molecular basis of CRC,there is a growing expectation on the development of diagnostic tests based on more sensitive and specific molecular markers and those tests may provide a breakthrough to the limitations of current screening tests for CRC.In this review,the molecular basis of CRC development,the characteristics and applications of different non-invasive molecular biomarkers,as well as the technologies available for the detection were discussed.This review intended to provide a summary on the current and future molecular diagnostics in CRC and its pre-malignant state,colorectal adenoma. | Andy Hin-Fung Tsang Ka-Ho Cheng Apple Siu-Ping Wong Simon Siu-Man Ng Brigette Buig-Yue Ma Charles Ming-Lok Chan Nancy Bo-Yin Tsui Lawrence Wing-Chi Chan Benjamin Yat-Ming Yung Sze-Chuen Cesar Wong | 2014 | World Journal of Gastroenterology2014，20，14： | 7 |
| 17 | Highly efficient hybrid warm white organic light-emitting diodes using a blue thermally activated delayed fluorescence emitter: exploiting the external heavy-atom effect显示文摘To attain high efficiencies in hybrid white organic light-emitting diodes(WOLEDs),mutual quenching of the fluorophors and phosphors should be minimized.Efforts have been devoted to reducing the triplet quenching of phosphors;however,the quenching of fluorophors by the external heavy-atom effect(EHA)introduced by the phosphors is often ignored.Here,we observed that conventional fluorophors and fluorophors with thermally activated delayed fluorescence(TADF)behave differently in the presence of EHA perturbers.The efficiencies of the conventional fluorophors suffer greatly from the EHA,whereas the TADF fluorophors exhibit negligible changes,which makes TADF materials ideal fluorophors for hybrid devices.WOLEDs using a blue TADF fluorophor and an orange phosphor achieve a maximum forward viewing external quantum efficiency of 19.6%and a maximum forward viewing power efficiency of 50.2 lm W^(-1),among the best values for hybrid WOLEDs.This report is the first time that the EHA effect has been considered in hybrid WOLEDs and that a general strategy toward highly efficient hybrid WOLEDs with simple structures is proposed. | Dongdong Zhang Lian Duan Yunge Zhang Minghan Cai Deqiang Zhang Yong Qiu | 2015 | Light(Science & Applications)2015，4，1： | 6 |
| 18 | 基于Lagrange松弛分解的多产品生产—分销系统的联合决策显示文摘考虑全球制造环境下多产品生产分销网络系统中的联合物流决策问题,包括供应商指定的生产任务、生产批量、供应商和用户之间的年运输量和订货批量,提出了基于Lagrange松弛的两层分解启发式算法(LRD)来求解联合决策模型(JDM-M),其中第一层是供应商指定的生产任务、生产批量和运输流量的联合决策(APLS-TF),第二层是运输和订货批量的联合决策(TOQ-M)。仿真分析表明LRD对于大规模的集成决策问题是行之有效的方法。 | 唐加福 Kai-Leung Yung | 2005 | 机械工程学报2005，41，8： | 6 |
| 19 | Preoperative CA 125 is significant indicator of curative resection in gastric cancer patients显示文摘AIM: To investigate the correlation among tumor markers, curative resection, and recurrence in gastric cancer.METHODS: The patients with preoperative tumormakers [Carcinoembryonic antigen, Carbohydrate antigen(CA) 19-9, and CA 125] and elective gastrectomy between January 2000 and December 2009 at Chungbuk National University Hospital were enrolled in this study. We analyzed the relationship among the tumor makers, curative resection and recurrence, retrospectively.RESULTS: Among the 679 patients with gastric cancer, curative resection was 93.6%(n = 636) and noncurative resection was 6.4%(n = 43). The independent risk factors for the non-curative resection were tumor location and the positivity of preoperative serum CA 19-9 and CA 125 levels. After curative resection, the independent prognostic risk factors for recurrence in curative resection were gender, stage, and preoperative increased serum CA 125 level(HR = 2.431, P =0.020), in a multivariate analysis. CONCLUSION: Preoperative CA 125 is a useful predictive biomarker for curative resection and prognostic biomarker for recurrence in gastric cancer patients. | Dae Hoon Kim Hyo Yung Yun Dong Hee Ryu Hye-Suk Han Joung-Ho Han Soon Man Yoon Sei Jin Youn | 2015 | World Journal of Gastroenterology2015，21，4： | 6 |
| 20 | Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients显示文摘Dear Editor,The ongoing coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus-2(SARSCoV-2)is a serious threat to global public health,and is imposing severe burdens on human society.Several candidate vaccines against SARS-CoV-2 are now undergoing clinical trials.The Spike(S)protein of SARS-CoV-2 is widely considered as a promising antigen.However. | Bao-zhong Zhang Ye-fan Hu Lin-lei Chen Thomas Yau Yi-gang Tong Jing-chu Hu Jian-piao Cai Kwok-Hung Chan Ying Dou Jian Deng Xiao-lei Wang Ivan Fan-Ngai Hung Kelvin Kai-Wang To Kwok Yung Yuen Jian-Dong Huang | 2020 | Cell Research2020，30，8： | 5 |
您所在的机构暂未开通此部分的功能，请联系管理员