|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Soil Organic Carbon Content and Distribution in a Small Landscape of Dongguan, South China显示文摘Global warming has become an increasing concern, and using soil as a carbon sink to sequester carbon dioxide has attracted much attention in recent years. In this study, soil organic carbon (SOC) content and organic carbon density were estimated based on a soil survey of a small landscape in Dongguan, South China, with spatial heterogeneity of SOC distribution and the impacts of land-use patterns on soil organic carbon content assessed. Field sampling was carried out based on a 150 m×150 m grid system overlaid on the topographic map of the study area and samples were collected in three 20-cm layers to a depth of 60 cm. Spatial variability in the distribution of SOC was assessed using the Kruskal-Wallis test. Results showed that SOC in the topsoil layer (0-20 cm) was not much higher or even lower in some sites than the underlying layers, and except for the two sites covered with natural woodland, it did not exhibit a pronounced vertical gradient. The difference in both horizontal and vertical distribution of SOC was not statistically significant. However, in the topsoil layer among land-use/land-cover patterns, significant differences (P≤0.05) in SOC distribution existed, indicating that management practices had great impact on SOC content. SOC storage in the study area to a depth of 20, 40, and 60 cm was estimated as 2.13×106 kg, 3.46×106 kg, and 4.61×106 kg, respectively. | SU Zhi-Yao XIONG Yong-Mei ZHU Jian-Yun YE Yong-Chang YE Mai | 2006 | Pedosphere2006，16，1： | 22 |
| 2 | A new prognostic histopathologic classification of nasopharyngeal carcinoma显示文摘Background:The current World Health Organization(WHO) classification of nasopharyngeal carcinoma(NPC) con?veys little prognostic information.This study aimed to propose an NPC histopathologic classification that can poten?tially be used to predict prognosis and treatment response.Methods:We initially developed a histopathologic classification based on the morphologic traits and cell differentia?tion of tumors of 2716 NPC patients who were identified at Sun Yat?sen University Cancer Center(SYSUCC)(training cohort).Then,the proposed classification was applied to 1702 patients(retrospective validation cohort) from hospitals outside SYSUCC and 1613 patients(prospective validation cohort) from SYSUCC.The efficacy of radiochemotherapy and radiotherapy modalities was compared between the proposed subtypes.We used Cox proportional hazards models to estimate hazard ratios(HRs) with 95% confidence intervals(CI) for overall survival(OS).Results:The 5?year OS rates for all NPC patients who were diagnosed with epithelial carcinoma(EC;3708 patients),mixed sarcomatoid?epithelial carcinoma(MSEC;1247 patients),sarcomatoid carcinoma(SC;823 patients),and squamous cell carcinoma(SCC;253 patients) were 79.4%,70.5%,59.6%,and 42.6%,respectively(P < 0.001).In mul?tivariate models,patients with MSEC had a shorter OS than patients with EC(HR = 1.44,95% CI = 1.27–1.62),SC(HR = 2.00,95% CI = 1.76–2.28),or SCC(HR = 4.23,95% CI = 3.34–5.38).Radiochemotherapy significantly improved survival compared with radiotherapy alone for patients with EC(HR 49–0.75),and possibly for those with SCC(HR = 0.67,95% CI = 0.56–0.80),MSEC(HR = 0.58,95% CI = 0..74–1.28).= 0.63;95% CI = 0.40–0.98),but not for patients with SC(HR = 0.97,95% CI = 0Conclusions:The proposed classification offers more information for the prediction of NPC prognosis compared with the WHO classification and might be a valuable tool to guide treatment decisions for subtypes that are associ?ated with a poor prognosis. | Hai-Yun Wang Yih-Leong Chang Ka-Fai To Jacqueline S.G.Hwang Hai-Qiang Mai Yan-Fen Feng Ellen T.Chang Chen-Ping Wang Michael Koon Ming Kam Shie-Lee Cheah Ming Lee Li Gao Hui-Zhong Zhang Jie-Hua He Hao Jiang Pei-Qing Ma Xiao-Dong Zhu Liang Zeng Chun-Yan Chen Gang Chen Ma-Yan Huang Sha Fu Qiong Shao An-Jia Han Hai-Gang Li Chun-Kui Shao Pei-Yu Huang Chao-Nan Qian Tai-Xiang Lu Jin-Tian Li Weimin Ye Ingemar Ernberg Ho Keung Ng Joseph T.S.Wee Yi-Xin Zeng Hans-Olov Adami Anthony T.C.Chan Jian-Yong Shao | 2016 | Chinese Journal of Cancer2016，35，6： | 10 |
| 3 | Adult endothelial progenitor cells from human peripheral blood maintain monocyte/macrophage function throughout in vitro culture显示文摘密度坡度 centrifugation 从外部血孤立的 Mononuclear 房间(MNC ) 是人的 fibronectin 涂的文化盘子上的 plated 并且在 EGM-2 有教养中等。依附塑造锭子的房间,由一些调查者作为 endothelial 祖先房间(EPC ) 报导了,从支持者回合房间伸长了,但是没从以前想了的房间的一个小数字增殖。主要 EPC 的生长曲线证明房间几乎没有很少 proliferative 能力。当他们能也表示 CD14 时,流动 cytometry 分析证明房间能表示一些 endothelial 系标记,它在整个文化被认为单核白血球 / 巨噬细胞系的一个标记。在 endothelial 函数试金,房间比在反向的抄写聚合酶的成熟 endothelial 房间锁住反应并且没显示一个能力在 vitro 在 angiogenesis 试金开发像试管的结构表明了 eNOS 的表示的底层。在这研究,我们由低密度的脂蛋白(Dil-Ac-LDL ) 和印度墨水举起测试的联合标记 Dil 的乙酰 ated 识别了 EPC 的单音的似细胞的功能。所有房间是双的为在天的 Dil-Ac-LDL 和印度墨水举起积极 4 文化, 14 和 28,它意味着 EPC 在整个文化维持了单音的似细胞的功能。因此,尽管从外部 MNC 的成年 EPC 有一些 endothelial 系性质,他们维持典型 monocytic 功能并且几乎没有很少 proliferative 能力。 | Shi Ju Zhang Hao Zhang Ying Jie Wei Wen Jun Su Zhong Kai Liao Mai Hou Jian Ye Zhou Sheng Shou Hu | 2006 | Cell Research2006，16，6： | 9 |
| 4 | Famitinib in combination with concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 1, open-label, dose-escalation Study显示文摘Background:Famitinib is a tyrosine kinase inhibitor against multiple targets,including vascular endothelial growth factor receptor 2/3,platelet-derived growth factor receptor,and stem cell factor receptor(c-kit).Previous studies have demonstrated anti-tumour activities of famitinib against a wide variety of advanced-stage solid cancers.We aimed to determine the safety and efficacy of famitinib with concurrent chemoradiotherapy(CCRT)in patients with locoregionally advanced nasopharyngeal carcinoma(NPC).We also evaluated the feasibility of contrast-enhanced ultrasound(D-CEUS)as a predictor of early tumour response to famitinib and to correlate functional parameters with clinical efficacy.Methods:The trial was conducted in subjects with stage III or IVa-b NPC using a 3+3 design of escalating fami-tinib doses.Briefly,subjects received 2 weeks of famitinib monotherapy followed by 7 weeks of famitinib plus CCRT.D-CEUS of the neck lymph nodes was performed at day 0,8 and 15 after famitinib was administered before starting concurrent chemoradiotherapy.End points included safety,tolerability and anti-tumour activity.Results:Twenty patients were enrolled(six each for 12.5,16.5 and 20 mg and two for 25 mg).Two patients in the 25 mg cohort developed dose-limiting toxicities,including grade 4 thrombocytopenia and grade 3 hypertension.The most common grade 3/4 adverse events were leukopenia,neutropenia and radiation mucositis.D-CEUS tests showed that more than 60%of patients achieved a perfusion parameter response after 2 weeks taking famitinib alone,and the parameter response was associated with disease improvement.In the famitinib monotherapy stage,three patients(15%)showed partial responses.The complete response rate was 65%at the completion of treatment and 95%3 months after the treatment ended.After a median follow-up of 44 months,the 3-year progression-free survival(PFS)and distant metastasis-free survival were 70%and 75%,respectively.Subjects with a decrease of perfusion parameter response,such as peak intensity decreased at least 30%after 1 week of famitinib treatment,had higher 3-year PFS(90.9%vs.44.4%,95%CI 73.7%-100%vs.11.9%-76.9%,P<0.001)than those with an increase or a reduction of less than 30%.Conclusions:The recommended famitinib dose for phase II trial is 20 mg with CCRT for patients with local advanced NPC.D-CEUS is a reliable and early measure of efficacy for famitinib therapies.Further investigation is required to confirm the effects of famitinib plus chemoradiotherapy. | Qiuyan Chen Linquan Tang Na Liu Feng Han Ling Guo Shanshan Guo Jianwei Wang Huai Liu Yanfang Ye Lu Zhang Liting Liu Pan Wang Yingqin Li Qingmei He Xiaoqun Yang Qingnan Tang Yang Li YuJing Liang XueSong Sun Chuanmiao Xie Yunxian Mo Ying Guo Rui Sun Haoyuan Mo Kajia Cao Xiang Guo Musheng Zeng Haiqiang Mai Jun Ma | 2018 | Cancer Communications2018，38，1： | 6 |
| 5 | Ordered semiconductor ZnO nanowire arrays and their photoluminescence properties显示文摘 | Li Y Mai Y W Ye L | | 0，，： | 5 |
| 6 | Relationship Between Grain Boundary Segregation of Antimony and Temper Embrittlement in Titanium-Doped Nickel-Chromium Steel显示文摘The antimony segregation at grain boundary was observed and the temper embrittlement in titanium-doped nickel-chromium steel was analyzed.It is concluded that the antimony segregation at grain boundary is nonequilibium and the kinetics of temper embrittlement agrees well with those of nonequilibrium antimony segregation at grain boundary.Besides,the mechanism of nonequilibrium antimony segregation at grain boundary proved to be the most satisfactory one among the existing mechanisms to interpret the antimony-induced embrittlement kinetics in the nickel-chromium steel.Based on these,the activation energy and frequency factor of diffusion of antimony-vacancy complexes were obtained according to the concept of critical time in nonequilibrium grain boundary segregation theory. | ZHENG Lei ZHANG Mai cang DONG Jian-xin MENG Ye | 2011 | Journal of Iron and Steel Research(International)2011，18，1： | 4 |
| 7 | Mechanical loading induced expression of bone morphogenetic protein-2, alkaline phosphatase activity, and collagen synthesis in osteoblastic MC3T3-E1 cells显示文摘 | LU Hong-fei MAI Zhi-hui XU Ye WANG Wei AI Hong | 2012 | Chinese Medical Journal2012，，22： | 3 |
| 8 | Diagnosis and management of acquired thrombotic thrombocy- topenic purpura in southeast China: a single center experience of 60 cases显示文摘 | Xinping Zhou XingnongYe Yanling Ren Chen Mei Liya Ma Jiansong Huang Weilai Xu Juying Wei Li Ye Wenyuan Mai Wenbin Qian Haitao Meng Jie Jin Hongyan Tong | 2016 | Frontiers of Medicine2016，10，4： | 2 |
| 9 | Insights into flavonoid biosynthesis during cucumber fruit peel coloration based on metabolite profiling and transcriptome analyses显示文摘The fruit peel color is a crucial trait of cucumber.To better understand the molecular mechanisms underlying cucumber peel coloration,we compared the UPLC-ESI-MS/MS-based flavonoid metabolomic and RNA sequencing-based transcriptomic profiling of the brown peeled cucumber line‘PW’at six developmental stages.A total of 210 flavonoid metabolites were identified.Of which,117 flavonoid metabolites were differentially accumulated.In this study,weighted gene co-expression network analysis combined with Kyoto Encyclopedia of Gene and Genomes enrichment analysis revealed key genes coding for seven enzymes and eight transcription factors(TFs)associated with flavonoid biosynthesis.Among them,the R2R3MYB CsaV3_4G001130 is the best candidate gene that is responsible for controlling mature fruit colors in cucumber.Sanger sequencing revealed one nonsynonymous SNP in the exon of CsaV3_4G001130 among the selected 11 cucumber lines,which introduced a premature stop codon,generating a truncated protein in pale yellow or creamy peeled fruits.Yeast two-hybrid assays showed a direct interaction of CsaV3_4G001130 with the bHLH TF CsaV3_1G002260 and the WD40 protein CsaV3_5G001800.However,the interactions were influenced by the nonsynonymous SNP we identified.Our finding revealed that the integrated transcriptome and metabolome analysis further demonstrated that the abundance of some pigmented flavonoids(especially anthocyanins and chalcones)contributed to the coloration of‘PW’fruits.These findings pave the way for elucidation of flavonoid biosynthesis and improvement of cucumber peel color in the future. | Shuying He Yi Ye Ying Yuan Mai Lv Meixing Wang Qiang Xu Xuewen Xu Xuehao Chen | 2023 | Horticultural Plant Journal2023，9，4： | 2 |
| 10 | Interface end theory and re-evaluation in interfacial strength test methods显示文摘 | Xing Ji Ying Dai Bai-Lin Zheng Lin Ye Yiu-Wing Mai | | 0，，： | 1 |
| 11 | Simulation of Temperature and Curing Profiles in Pultruded Composite Rods显示文摘 | YE L MAI Y W | 1999 | Composites Science and Technology1999，58，2： | 1 |
| 12 | Sisal fiber and its composites:a review of recent development显示文摘 | LI Y MAI Y W YE L | 2000 | Composites Science and Technology2000，60，： | 1 |
| 13 | Investigation on diffusion bonding characteristics of SiC particulate reinforced aluminum metal matrix composites (Al/SiCp-MMC)显示文摘 | ZHANG X P YE L MAI Y W QUAN G F WEI W | 1999 | Composites: Part A1999，30，： | 1 |
| 14 | Crack tip field for fast fracture of an elastic-plastic-viscoplastic material incorporated with quasi-damage, Part I: Large damage regime 显示文摘 | Lu M Mai Y W Ye L | 2001 | International Journal of Solids and Structures2001，38，： | 1 |
| 15 | Soy germ isoflavones improve menopausal symptoms but have no effect on blood lipids in early postmenopausal Chinese women: a randomized placebo-controlled trial显示文摘 | Yan-bin Ye Zi-lian Wang Shu-yu Zhuo Wei Lu Hui-fang Liao MarianA. Verbruggen Shi Fang Hai-yan Mai Yu-ming Chen Yi-xiang Su | 2012 | Menopause: The Journal of The North American Menopause Society2012，，7： | 1 |
| 16 | Sisal fiber and its composites:a review of recent development显示文摘 | Li Y Mai Y W Ye L | 2000 | Composites Science and Technology2000，60，11： | 1 |
| 17 | Sisal fibre and its composites: a review of recent developments显示文摘 | Yan Li Yiuwing Mai Lin Ye | 2000 | Composites Science and Technology2000，60，： | 1 |
| 18 | Effects of fibre/matrix adhesion on carbon-fibre-reinforced mental laminates-Ⅱ,impact behaviour显示文摘 | Lawcock G D Ye L Mai Y W | 1997 | Composites Science and Technology1997，57，12： | 1 |
| 19 | Sisal fibre and its composites : a review of re- cent developments 显示文摘 | Li Y Mai Y W Ye L | 2000 | Composites Science and Technology2000，60，11： | 1 |
| 20 | Sisal fiber and its composites:A review of recent developments 显示文摘 | Li Y Mai Y-W Ye L | 2000 | Comp Sci Technol2000，60，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员