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| 1 | Chemical routes toward long-lasting lithium/sulfur cells显示文摘锂 / 硫(Li/S ) 房间有大潜力成为主流的第二等的电池由于他们的超离频理论特定的精力。为 Li/S 房间的主要挑战是绝缘的硫引起自然的不稳定的骑车表演并且中间的 polysulfide 产品高溶解度。几年开发各种各样的花式的碳 nanostructures 的努力,试着身体上包含 polysulfides,还没推足够长的房间周期生活与当前的李离子房间竞争。这评论的焦点在在为通过在碳矩阵雇用功能的组和添加剂套住 polysulfides 的化学结合策略的最近的进步上。理解在 polysulfides 和功能的组之间的化学相互作用的工作机制上的研究结果(例如 O, B,反及 S ) 在碳,在控告 / 解除期间的矩阵,基于金属的添加剂,或聚合物添加剂被讨论。 | Meinan Liu Fangmin Ye Wanfei Li Hongfei Li Yuegang Zhang | 2016 | Nano Research2016，9，1： | 13 |
| 2 | Polyaniline-modified cetyltrimethylammonium bromide- graphene oxide-sulfur nanocomposites with enhanced performance for lithium-sulfur batteries显示文摘 | Yongcai Qiu Wanfei Li Guizhu Li Yuan Hou Lisha Zhou Hongfei Li Meinan Liu Fangmin Ye Xiaowei Yang Yuegang Zhang | 2014 | Nano Research2014，7，9： | 11 |
| 3 | Bispecific prodrug nanoparticles circumventing multiple immune resistance mechanisms for promoting cancer immunotherapy显示文摘Cancer immunotherapy is impaired by the intrinsic and adaptive immune resistance.Herein,a bispecific prodrug nanoparticle was engineered for circumventing immune evasion of the tumor cells by targeting multiple immune resistance mechanisms.A disulfide bond-linked bispecific prodrug of NLG919 and JQ1(namely NJ) was synthesized and self-assembled into a prodrug nanoparticle,which was subsequently coated with a photosensitizer-modified and tumor acidity-activatable diblock copolymer PHP for tumor-specific delivery of NJ.Upon tumor accumulation via passive tumor targeting,the polymeric shell was detached for facilitating intracellular uptake of the bispecific prodrug.NJ was then activated inside the tumor cells for releasing JQ1 and NLG919 via glutathione-mediated cleavage of the disulfide bond.JQ1 is a bromodomain-containing protein 4 inhibitor for abolishing interferon gamma-triggered expression of programmed death ligand 1.In contrast,NLG919 suppresses indoleamine-2,3-dioxygenase 1-mediated tryptophan consumption in the tumor microenvironment,which thus restores robust antitumor immune responses.Photodynamic therapy(PDT) was performed to elicit antitumor immunogenicity by triggering immunogenic cell death of the tumor cells.The combination of PDT and the bispecific prodrug nanoparticle might represent a novel strategy for blockading multiple immune evasion pathways and improving cancer immunotherapy. | Jiayi Ye Bo Hou Fangmin Chen Shunan Zhang Muya Xiong Tianliang Li Yechun Xu Zhiai Xu Haijun Yu | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 4 |
| 4 | Dual-targeting prodrug nanotheranostics for NIR-Ⅱfluorescence imaging-guided photo-immunotherapy of glioblastoma显示文摘Glioblastoma(GBM) therapy is severely impaired by the blood-brain barrier(BBB) and invasive tumor growth in the central nervous system.To improve GBM therapy,we herein presented a dual-targeting nanotheranostic for second near-infrared(NIR-Ⅱ) fluorescence imaging-guided photoimmunotherapy.Firstly,a NIR-Ⅱ fluorophore MRP bearing donor-acceptor-donor(D-A-D) backbone was synthesized.Then,the prodrug nanotheranostics were prepared by self-assembling MRP with a prodrug of JQ1(JPC) and T7 ligand-modified PEG5k-DSPE.T7 can cross the BBB for tumor-targeted delivery of JPC and MRP.JQ1 could be restored from JPC at the tumor site for suppressing interferon gamma-inducible programmed death ligand 1 expression in the tumor cells.MRP could generate NIR-Ⅱ fluorescence to navigate 808 nm laser,induce a photothermal effect to trigger in-situ antigen release at the tumor site,and ultimately elicit antitumor immunogenicity.Photo-immunotherapy with JPC and MRP dual-loaded nanoparticles remarkably inhibited GBM tumor growth in vivo.The dual-targeting nanotheranostic might represent a novel nanoplatform for precise photo-immunotherapy of GBM. | Fenglin Li Yi Lai Jiayi Ye Madiha Saeed Yijing Dang Zhifeng Zou Fangmin Chen Wen Zhang Zhiai Xu | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 2 |
| 5 | Software defined industrial network architecture for edge computing offloading显示文摘The integration of the Internet and the traditional manufacturing industry makes the industrial Internet of things(IIoT) as a popular research topic. However, traditional industrial networks continue to face challenges of resource management and limited raw data storage and computation capacity. A novel software defined industrial network(SDIN) architecture was proposed to address the existing drawbacks in IIoT such as resource utilization, data processing and storage, and system compatibility. The architecture is developed based on the software defined network(SDN) architecture, combining hierarchical cloud and fog computing and content-aware caching technologies. Based on the SDIN architecture, two types of edge computing strategies in industrial applications are discussed. Different scenarios and service requirements are considered. The simulation results confirm that the SDIN architecture is feasible and effective in the application of edge computing offloading. | Xu Fangmin Ye Huanyu Cui Shaohua Zhao Chenglin Yao Haipeng | 2019 | The Journal of China Universities of Posts and Telecommunications2019，26，1： | 2 |
| 6 | Suppression of starch synthase I(SSI) by RNA interference alters starch biosynthesis and amylopectin chain distribution in rice plants subjected to high temperature显示文摘Based on known cDNAs of rice starch synthase isoforms,we constructed dsRNA interference vectors for starch synthase I(SSI)to produce transgenic plants containing starch with a moderately high amylose content.We investigated the effect of SSI suppression on grain quality traits,starch biosynthesis,and amylopectin chain distribution in rice plants exposed to two different temperature regimes.The activities and transcripts of BEs,DBEs,and other SS isoforms were further investigated to clarify the effect of SSI suppression on these key enzymes and their specific isoforms under different temperature treatments.Suppression of SSI by RNAi altered grain starch component and amylopectin chain distribution,but it exerted only a slight effect on total starch content(%)and accumulation amount(mg kernel?1)and on starch granule morphology and particle size distribution.Under normal temperature(NT),insignificant differences in kernel weight,chalky kernel proportion,chalky degree,and starch granule morphology between SSI-RNAi line and its wild type(WT)were observed.However,amylose content(AC)level and granule-bound starch synthase(GBSS)activity in rice endosperms were markedly increased by SSI-RNAi suppression.The chalky kernel proportion and chalky degree of SSIRNAi lines were significantly higher than those of WT under high temperature(HT)exposure at filling stage.Inhibition of SSI by RNAi affected amylopectin chain distribution and raised starch gelatinization temperature(GT)in two ways:directly from the SSI deficiency itself and indirectly by reducing BEIIb amounts in an SSI-deficient background.The deficiency of SSI expression led to an alteration in the susceptibility of grain chalkiness occurrence and starch gelatinization temperature to HT exposure,owing to a pleiotropic effect of SSI deficiency on the expression of other genes associated with starch biosynthesis. | Qian Zhao Xiaoxia Du Zhanyu Han Yu Ye Gang Pan Muhammad-Asad-Ullah Asad Qifa Zhou Fangmin Cheng | 2019 | The Crop Journal2019，7，5： | 2 |
| 7 | A new type of longitudinally driven GMI effect of FeCo-based alloy显示文摘On investigating the longitudinally driven GMI effect of the DC annealed Fe36Co36Nb4Si4.8B19.2 alloy rib-bon,the current density was 3.2×107 A/m2,the GMI effect responds sensitively(the sensitivity is as high as 2440.2%/(A.m?1))to weak magnetic field after a 600-second annealing.The experimental result shows that the sensitivity is closely related to annealing current density,driven current frequency and eroded thickness. | MAN QiKui FANG YunZhang SUN HuaiJun YE FangMin | 2008 | Chinese Science Bulletin2008，53，3： | 2 |
| 8 | AFM research on the mechanism of Fe-based alloy stress annealed inducing magnetic anisotropy显示文摘The cross-section of the Fe-based alloy (Fe73.5Cu1Nb3Si13.5B9) ribbon annealed at 540℃ under various tensile stress was investigated with atomic force microscope (AFM). The stress effect mechanism in Fe-based alloy ribbon tensile stress an-nealed inducing transverse magnetic anisotropy field was studied using the X-ray diffraction spectra and longitudinal drive giant magneto-impedance effect curves, and the model of direction dominant in encapsulated grain agglomeration was es-tablished. The relationship between the direction dominant in encapsulated grain agglomeration and magnetic anisotropy field was disclosed. | FANG YunZhang ZHENG JinJu SHI FangYe WU FengMin SUN HuaiJun LIN GenJin YANG XiaoHong MAN QiKui YE FangMin | 2008 | Science China(Technological Sciences)2008，51，9： | 0 |
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