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515篇 您的检索式：作者名="YATES D"

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	题名	作者	年代	出处	被引量
1	Oxidative stress in alcohol-related liver disease显示文摘Alcohol consumption is one of the leading causes of the global burden of disease and results in high healthcare and economic costs.Heavy alcohol misuse leads to alcohol-related liver disease,which is responsible for a significant proportion of alcohol-attributable deaths globally.Other than reducing alcohol consumption,there are currently no effective treatments for alcohol-related liver disease.Oxidative stress refers to an imbalance in the production and elimination of reactive oxygen species and antioxidants.It plays important roles in several aspects of alcohol-related liver disease pathogenesis.Here,we review how chronic alcohol use results in oxidative stress through increased metabolism via the cytochrome P4502E1 system producing reactive oxygen species,acetaldehyde and protein and DNA adducts.These trigger inflammatory signaling pathways within the liver leading to expression of pro-inflammatory mediators causing hepatocyte apoptosis and necrosis.Reactive oxygen species exposure also results in mitochondrial stress within hepatocytes causing structural and functional dysregulation of mitochondria and upregulating apoptotic signaling.There is also evidence that oxidative stress as well as the direct effect of alcohol influences epigenetic regulation.Increased global histone methylation and acetylation and specific histone acetylation inhibits antioxidant responses and promotes expression of key pro-inflammatory genes.This review highlights aspects of the role of oxidative stress in disease pathogenesis that warrant further study including mitochondrial stress and epigenetic regulation.Improved understanding of these processes may identify novel targets for therapy.	Huey K Tan Euan Yates Kristen Lilly Ashwin D Dhanda	2020	World Journal of Hepatology2020，12，7：	6
2	Primary structure of Gamma-bungarotoxin, a new postsynaptic neurotoxin from venom of Bungarus multicinctus 显示文摘	Aird S D Womble G C Yates J R	1999	Toxicon1999，37，4：	1
3	Observation of a chicken embryo lethal orphan (CELO) virus 显示文摘	Yates V J Fry D E	1957	Am J Vet Res1957，18，：	1
4	Nutrient require- ment and cycling in energy crops 显示文摘	Christian D G Riche A B Yates N E	1997	Sustainable Agri- culture for Food Energy and Industry1997，2，：	1
5	Role of exhaled nitric oxide in asthma显示文摘	Yates D H	2001	Immunol Cell Biol2001，79，2：	1
6	Persistence of maternal antibodies against Mycoplasma agassizii in desert tortoise hatchlings显示文摘	SCHUMACHER I M ROSTAL D C YATES R A	1999	Am J Vet Res1999，60，：	1
7	X-ray analysis of fluidized beds and other multiphase systems显示文摘	YATES J CHEESMAN D LETTIERI P	2005	Chemical Engineering Science2005，，2：	1
8	Large-scale analysis of the yeast proteome by multidimensional protein identification technology 显示文摘	Washburn MP Wolters D Yates JR	2001	Nat Biotechnol2001，19，：	1
9	Stochastic power control for cellular radio systems 显示文摘	SENNUR U YATES R D	1998	IEEE Trans on Communication1998，46，6：	1
10	A framework for uplink power control in cellular radio systems显示文摘	Yates R D	1995	IEEE Journal on Selected Areas in Communications1995，13，7：	1
11	Formation of Rod-shaped Calcite Crystals by Microemulsion-based Synthesis显示文摘	Liu D Yates M Z	2006	Langmuir2006，22，：	1
12	Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial):randomised placebo-controlled trial显示文摘	ROBERTS I YATES D SANDERCOCK P	2004	Lancet2004，364，9442：	1
13	Wearable electro- encephalography显示文摘	Casson A J Yates D Smith S	2010	IEEE Engineering in Medicine and Bi- ology Magazine2010，29，3：	1
14	Biological control of Fusarium moniliforme in maize 显示文摘	Bacon C W Yates I E Hinton D M	2001	Environ- mental Health Perspectives2001，109，2：	1
15	Multiple EBNAl-binding sites are required to form an EBNAl-dependent enhancer and to aetivate a minimal replieative origin within oriP of Epstein-Barr virus 显示文摘	WYSOKENSKI D A YATES J L	1989	J Virol1989，63，：	1
16	A framework for Uplink Power Control in Cellular Radio Systems显示文摘	YATES R D	1995	IEEE Journal On Selected Areas In Communications1995，13，7：	1
17	Real-time three-dimensional fetal echocardiography-optima] imaging windows显示文摘	Deng J Sullivan ID Yates R Voge] M Mcdonald D Linney AD Rodeck CH Anderson Rlt	2002	Ultrasound Med Biol2002，28，9：	1
18	Large-scale analysis of the yeast proteome by multidimensional protein identification technology显示文摘	Washburn MP Wolters D Yates JR	2001	Nat Biotechnol2001，19，3：	1
19	The yield and composition of switchgrass and coastal panic grass grown as a biofuel in Southern England显示文摘	Christian D Riche A Yates N	2008	Bioresource Technology2008，83，：	1
20	A framework for uplink power control in cellular radio systems 显示文摘	YATES R D	1995	IEEE J Select Areas Communication1995，13，7：	1

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