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| 1 | Embolization of splenorenal shunt associated to portal vein thrombosis and hepatic encephalopathy显示文摘Hepatic encephalopathy(HE)is a cognitive disturbance characterized by neuropsychiatric alterations.It occurs in acute and chronic hepatic disease and also in patients with portosystemic shunts.The presence of these portosystemic shunts allows the passage of nitrogenous substances from the intestines through systemic veins without liver depuration.Therefore,the embolization of these shunts has been performed tocontrol HE manifestations,but the presence of portal vein thrombosis is considered a contraindication.In this presentation we show a cirrhotic patient with severe HE and portal vein thrombosis who was submitted to embolization of a large portosystemic shunt.Case report:a 57 years-old cirrhotic patient who had been hospitalized many times for persistent HE and hepatic coma,even without precipitant factors.She had a wide portosystemic shunt and also portal vein thrombosis.The abdominal angiography confirmed the splenorenal shunt and showed other shunts.The larger shunt was embolized through placement of microcoils,and the patient had no recurrence of overt HE.There was a little increase of esophageal and gastric varices,but no endoscopic treatment was needed.Since portosystemic shunts are frequent causes of recurrent HE in cirrhotic patients,portal vein thrombosis should be considered a relative contraindication to perform a shunt embolization.However,in particular cases with many shunts and severe HE,we found that one of these shunts can be safely embolized and this procedure can be sufficient to obtain a good HE recovery.In conclusion,we reported a case of persistent HE due to a wide portosystemic shunt associated with portal vein thrombosis.As the patient had other shunts,she was successfully treated by embolization of the larger shunt. | Letícia de Campos Franzoni Fábio Cardoso de Carvalho Rafael Gomes de Almeida Garzon Fábio da Silva Yamashiro Laís Augusti Lívia Alves Amaral Santos Mariana de Souza Dorna Júlio Pinheiro Baima Talles Bazeia Lima Carlos Antonio Caramori Giovanni Faria Silva Fernando Gomes Romeiro | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 2 | Interactions between blood cells and retinal endothelium in endotoxic sepsis显示文摘 | Tsujikawa A Kiryu J Yamashiro K | 2000 | Hypertension2000，36，2： | 1 |
| 3 | Prostate stem cell antigen (PSCA) expression increases with high Gleason score, advanced stage and bone metastasis in prostate cancer 显示文摘 | Gu Z Thomas G Yamashiro J | 2000 | Oncogene2000，19，10： | 1 |
| 4 | In vitro and in vivo antimicrobial activities of T-381 I ME, a novel des-F (6)-quinolone 显示文摘 | Takahata M Mitsuyama J Yamashiro Y | 1999 | Antimicrob Agents Chemother1999，43，5： | 1 |
| 5 | VEGF blocking therapy in the treatment of cancer显示文摘 | Kandel JJ Yamashiro DJ | 2003 | Expert Opin Biol Ther2003，3，： | 1 |
| 6 | Redefining and Extending the Business Model with Information Technology:Dell Computer Corporation显示文摘 | KRAEMER K L DEDRICK J YAMASHIRO S | 2000 | The Information Society2000，16，1： | 1 |
| 7 | Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer显示文摘 | Gu Z Thomas G Yamashiro J | 2000 | Oncogene2000，19，： | 1 |
| 8 | Increased serum trypsin and elastase-1 levels in patients undergoing L -asparaginase therapy显示文摘 | Shimizu T Yamashiro Y Igarashi J | 1998 | Eur J Pediatr1998，157，7： | 1 |
| 9 | Bank loan portfolios and the monetary transmission mechanism显示文摘 | Haan W J Sumner S W Yamashiro G M | 2007 | Journal of Monetary Economics2007，54，： | 1 |
| 10 | Tumor ilecrosis factor increases the number of epidermal growth factor receptors on human fibroblasts 显示文摘 | PALOMBELLA V J YAMASHIRO D J MAXIFIELD F R | 1987 | J Biol Chem1987，262，5： | 1 |
| 11 | Prostate stem cell antigen (PSCA) expression increases with high gleason score,advanced stage and bone metastasis in prostate cancer显示文摘 | GU Z THOMAS G YAMASHIRO J | 2000 | Oncogene2000，19，10： | 1 |
| 12 | Inflammatory response after scatter laser photo- coagulation in nonphotocoagulated retina 显示文摘 | Nonaka A Kiryu J Tsujikawa A Yamashiro K Nishijima K Ka- mizuru H eta/ | 2002 | Invest Ophthal- mol V/s Sc/2002，43，4： | 1 |
| 13 | VEGF blocking thera- py in the treatment of cancer显示文摘 | Glade-Bender J JJ Kandel DJ Yamashiro | 2003 | Expert Opin Biol Ther2003，3，2： | 1 |
| 14 | Prostate stem cell antigen (PSCA) expression increases with high Gleason score, advanced stage and bone metastasis in prostate cancer 显示文摘 | Gu Z Thomas G Yamashiro J | 2000 | Oncogene2000，19，： | 1 |
| 15 | Simvastatin inhibits leukocyte accumulation and vascular permeability in the retinas of rats with streptozotocin-induced diabetes显示文摘 | Miyahara S Kiryu J Yamashiro K Miyamoto K Hirose F Tamura H | 2004 | Am J Pathol2004，164，5： | 1 |
| 16 | Simvastatin inhibits leu- kocyte accumulation and vascular permeability in the retinas of rats with streptozotocin-induced diabetes显示文摘 | Miyahara S Kiryu J Yamashiro K | 2004 | Am I Pathol2004，164，5： | 1 |
| 17 | Prostate stem cell antigen is overexpressed in prostate cancer metastases显示文摘 | LAM JS YAMASHIRO J SHINTAKU IP | 2005 | Clin Cancer Res2005，11，7： | 1 |
| 18 | Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer显示文摘 | Gu Z Thomas G Yamashiro J | 2000 | Oncogene2000，19，10： | 1 |
| 19 | Anti-prostate stem cell antigen monoclonal antibody 1G8 induces cell death in vitro and inhibits tumor growth in vivo via a Fc-independent mechanism显示文摘 | GU Z YAMASHIRO J KONO E | 2005 | Cancer Res2005，65，20： | 1 |
| 20 | Prostate stem cell antigen is a marker of late intermediate prostate epithelial cells显示文摘 | Tran CP Lin C Yamashiro J | 2002 | Mol Cancer Res2002，1，2： | 1 |
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