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| 1 | Separation of structurally related estrogens using isocratic elution pressurized capillary electrochromatography显示文摘 | Shaofeng Liu Zenghong Xie Xiaoping Wu Xucong Lin Liangqia Guo Guonan Chen | 2005 | Journal of Chromatography A2005，，2： | 1 |
| 2 | Solid phase extraction of lead (Ⅱ),copper (Ⅱ),cadmium (Ⅱ) and nickel (Ⅱ) using gallic acid-modified silica gel prior to determination by flame atomic absorption spectrometry显示文摘 | XIE Fazhi LIN Xucong WU Xiaoping | 2008 | Talanta2008，74，4： | 1 |
| 3 | 显示文摘 | ZHANG Jian WU Xiaoping LIN Xucong | 2007 | J Chromatogr: A2007，1154，12： | 1 |
| 4 | 显示文摘 | LIN Jian WU Xiaoping LIN Xucong | 2007 | J Chromatogr: A2007，1169，12： | 1 |
| 5 | Glycin-bonded silica monolithic column as zwitterionic stationary phase for hydrophilic interaction pressurized capillary electrochromatography 显示文摘 | LIN Xucong ZENG Wencan WANG Xiaochun | 2009 | J Sep Sci2009，32，1516： | 1 |
| 6 | Investigation of enantiomer recognition of molecuIarly imprinted polymeric monoliths in pressurized capillary electrochromatography screening the amino acids and their derivatives显示文摘 | LI Min LIN Xucong XIE Zenghong | 2009 | Journal of Chromatography A2009，1216，27： | 1 |
| 7 | Pharmacokinetics of ciprofloxacin in eels by high-perf-ormance liquid chromatography with fluorescence detection 显示文摘 | Guo Liangqia Xie Zenghong Lin Xucong | 2005 | Analytical Biochemistry2005，341，2： | 1 |
| 8 | Electroneutral silica -based hybrid monolith for hydrophilic interaction capil- lary electrochromatography 显示文摘 | Lin Xucong Wang Xiao Zhao Tingting | 2012 | Journal of Chromatography A2012，1260，： | 1 |
| 9 | Pharmacokinetics of ciprofloxacin in eels by high-performance liquid chromatography with fluorescence detection显示文摘 | GUO Liangqia XIE Zenghong LIN Xucong | 2005 | Analytical Biochemistry2005，341，2： | 1 |
| 10 | Triamine - bonded stationary phase for open tubular capillary electrochroma- tography显示文摘 | Zhang Xiaowei Lin Xucong Chen Zhenbin | 2010 | Journal of Separation Science2010，33，20： | 1 |
| 11 | Develop potential multi-target drugs by self-assembly of quercetin with amino acids and metal ion to achieve significant efficacy in anti-Alzheimer’s disease显示文摘Exploring multi-target drugs(MTDs)is a prevalent method against Alzheimer’s disease(AD).However,the current developed MTDs based on the“framework combination”technique or using flavonoids have not realized better healing effects owing to a complex metabolic process and low bioavailability.Here,we propose an alternative strategy to develop self-assembled nanoparticles(NPs)as MTDs using 9-fluorenylmethyloxycarbonyl-tryptophan(Fmoc-Trp),quercetin(Que),and Fe^(2+)as building blocks through coordination and electrostatic interaction to generate Fmoc-Trp-Fe^(2+)-Que(FTFQ)NPs.Whether in cell or in vivo,FTFQ NPs exhibited considerable biocompatibility attributing to the inherent biological affinity of assembly units.By combining the advantages of assemble approach and nanostructures,the obtained FTFQ NPs greatly enhanced the bioavailability of Que and displayed synergistic therapeutic effects through reducing Aβaggregation in direct/indirect means and eliminating the toxicity induced by ROS and Aβoligomer/fibrils.Furthermore,FTFQ NPs could obviously restore the AD zebrafish’s mobility and stimulus response ability.More importantly,developing self-assembly NPs as MTDs could be an efficient and general method to promote other novel MTDs by extending the assemble units to other drugs,peptides,and metal ions.Based on above benefits,these self-assembled NPs could be as potential MTDs and show great promising application in AD treatment. | Chunling Zhu Yuheng Yang Xiaowen Li Xingyu Chen Xucong Lin Xiaoping Wu | 2022 | Nano Research2022，15，6： | 0 |
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