|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The Chromosome-Level Genome Sequence of the Autotetraploid Alfalfa and Resequencing of Core Germplasms Provide Genomic Resources for Alfalfa Research显示文摘Alfalfa(Medicago sativa)is one of the most important forage crops in the world;however,its molecular genetics and breeding research are hindered due to the lack of a high-quality reference genome.Here,we report a de novo assembled 816-Mb high-quality,chromosome-level haploid genome sequence for‘Zhongmu No.1’alfalfa,a heterozygous autotetraploid.The contig N50 is 3.92 Mb,and 49165 genes are annotated in the genome.The alfalfa genome is estimated to have diverged from M.truncatula approximately 8 million years ago.Genomic population analysis of 162 alfalfa accessions revealed high genetic diversity,weak population structure,and extensive gene flow from wild to cultivated alfalfa.Genome-wide association studies identified many candidate genes associated with important agronomic traits.Furthermore,we showed that MsFTa2,a Flowering Locus T homolog,whose expression is upregulated in salt-resistant germplasms,may be associated with fall dormancy and salt resistance.Taken together,these genomic resources will facilitate alfalfa genetic research and agronomic improvement. | Chen Shen Huilong Du Zhuo Chen Hongwei Lu Fugui Zhu Hong Chen Xiangzhao Meng Qianwen Liu Peng Liu Lihua Zheng Xiuxiu Li Jiangli Dong Chengzhi Liang Tao Wang | 2020 | Molecular Plant2020，13，9： | 21 |
| 2 | A special numerical method for fluid-structure interaction problems subjected to explosion and impact loading显示文摘A three-dimensional(3D) embedded Eulerian-Lagrangian method is proposed to simulate the 3D fluid-structure interaction(FSI) problems subjected to explosion and impact loading. This method achieves a high-quality calculation of fluid and structure deformation by adding Lagrangian particles to Eulerian grids. The overall computational domain is solved by the Eulerian method, and the Lagrangian particles with specified volume and influence domains are used to track structural deformations. The bidirectional mapping of physical quantities is achieved using the weighted average of the influence domain, which are based on the topological relationship between Eulerian grids and Lagrangian particles. Then, the data dependence solution and parallel algorithm realization are presented for the large-scale numerical calculations of explosion and impact problems. Additionally, the corresponding parallel program is developed based on the message passing interface(MPI) standard, and the parallel efficiency of parallel hydrocode are tested. The numerical results of typical explosion and impact problems are compared with corresponding experimental data to verify the effectiveness of the method. These comparisons show that the embedded EulerianLagrangian method successfully combine the advantages of both the Eulerian and Lagrangian methods to efficiently calculate the processes of large deformation and dynamic damage to the materials. The results presented in this work provide a useful reference point for further research on explosion and impact problems. | NING JianGuo MENG FanLin MA TianBao XU XiangZhao | 2020 | Science China(Technological Sciences)2020，63，7： | 4 |
| 3 | pH-sensitive and biodegradable charge-transfer nanocomplex for second near-infrared photoacoustic tumor imaging显示文摘The emerging technique of photoacoustic imaging,especially in the near infra-red(NIR)window,permits high resolution,deep-penetration,clinically reliable sensing.However,few contrast agents are available that can specifically respond to intricate biological environments,and which are biodegradable and biocompatible.Herein,we in troduce a new class of pH-sensitive orga nic photoacoustic con trast age nt that operates in the second NIR window(NIR-II,960-1,700 nm),which is derived from the self-assembled charge-transfer nanocomplex(CTN)by 3,3',5,5'-tetramethylbenzidine(TMB)and its dication structure(TMB++).The unique NIR-ll-responsive CTN can specifically respond to pH change in the physiological range and allows noninvasive and sensitive visualization of the tumor acidic microenvironment(e.g.at pH5)in mice with higher signal-to-noise ratio.The CTN is biodegradable under physiological conditions(e.g.pH 7.4),which alleviates the biosafety concern of nan oparticle accumulati on in vivo.These results clearly show the pote ntial of the TMB/TMB++-based CTN as a promisi ng pH-activated and biodegradable molecular probe for specific tumor photoacoustic imaging in the NIR-II region. | Zhimin Wang Paul Kumar Upputuri Xu Zhen Ruochong Zhang Yuyan Jiang Xiangzhao Ai Zhijun Zhang Ming Hu Zhenyu Meng Yunpeng Lu Yuanjing Zheng Kanyi Pu Manojit Pramanik Bengang Xing | 2019 | Nano Research2019，12，1： | 3 |
| 4 | Experimental and theoretical investigation of the failure behavior of a reinforced concrete target under high-energy penetration显示文摘The dynamic mechanical properties of concrete and reinforced concrete targets subjected to high-speed projectile impact loading have a significant influence on the impact resistance of protective structures.In this study,high-speed projectile penetration and perforation of concrete and reinforced concrete structures was carried out to determine the high-energy impact loading.The failure behaviors of projectile penetration and perforation of the concrete and reinforced concrete targets were investigated,and the destruction characteristics of the targets were measured.An analytical model was established using the principle of minimum potential energy.The results show that the theoretical predictions are consistent with the experimental data,indicating that the energy method is effective for predicting the dynamic mechanical properties of concrete and reinforced concrete targets under high-speed projectile penetration. | Fanlin Meng Tianbao Ma Xiangzhao Xu | 2020 | Acta Mechanica Sinica2020，36，1： | 2 |
| 5 | Experimental Investigation on a Ceiling Capillary Radiant Heating System显示文摘 | Kang Weibin Zhao Min Liu Xing Meng Xiangzhao Zhang Lianying Hu Wangyang | 2015 | Energy Procedia2015，，： | 1 |
| 6 | From model to alfalfa:Gene editing to obtain semidwarf and prostrate growth habits显示文摘Alfalfa(Medicago sativa L.)is a nutritious forage crop with wide ecological adaptability.The molecular breeding of alfalfa is restricted by its heterozygous tetraploid genome and the difficult genetic manipulation process.Under time and resource constraints,we applied a more convenient approach.We investigated two MtGA3ox genes,MtGA3ox1 and MtGA3ox2,of Medicago truncatula,a diploid legume model species,finding that MtGA3ox1 plays a major role in GA-regulated plant architecture.Mutation of neither gene affected nitrogenase activity.These results suggest that MtGA3ox1 can be used in semidwarf and prostrate alfalfa breeding.Based on the M.truncatula MtGA3ox1 sequence,MsGA3ox1 was cloned from alfalfa,and two knockout targets were designed.An efficient CRISPR/Cas9-based genome editing protocol was used to generate msga3ox1 mutants in alfalfa.We obtained three lines that carried mutations in all four alleles in the T0 generation.Fifteen clonal plants were vegetatively propagated from each transgenic line using shoot cuttings.The plant height and internode length of msga3ox1 null mutants were significantly decreased.The number of total lateral branches,leaf/stem ratio and crude protein content of aerial plant parts of msga3ox1 mutants were significantly increased.Thus,we obtained semi-dwarf and prostrate alfalfa by gene editing. | Lihua Zheng Jiangqi Wen Jinling Liu Xiangzhao Meng Peng Liu Na Cao Jiangli Dong Tao Wang | 2022 | The Crop Journal2022，10，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员