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| 1 | Nifekalant in the treatment of life-threatening ventricular tachyarrhythmias显示文摘The aim of the present study is to review the literature and discuss nifekalant's potential use as a first aid drug in an emergency care setting.The PubMed database was used to identify papers,using Keywords nifekalant,MS-551,amiodarone and lidocaine.Nifekalant hydrochloride,formally known as MS-551,is a classⅢ antiarrhythmic agent which acts only by increasing the time course of myocardial repolarization.It was developed and is currently being used only in Japan for the treatment of ventricular tachyarrhythmias.It is a non-selective K+channel blocker without any β-blocking actions.Administration of nifekalant suppressed sustained ventricular tachyarrhythmias in acute coronary syndrome patients,and in cardiac arrest victims as well as during or after cardiac surgery.The major adverse effect of nifekalant is QT interval prolongation and occurrence of torsades de pointes which requires frequent monitoring of the QT interval during nifekalant infusion with adequate dose adjustment.Nifekalant is a possible effective antiarrhythmic agent for refractory ventricular tachyarrhythmias.Further clinical studies are required before nifekalant is routinely used in the emergency care setting. | Ioannis N Pantazopoulos Georgios T Troupis Charalampos N Pantazopoulos Theodoros T Xanthos | 2011 | World Journal of Cardiology2011，3，6： | 2 |
| 2 | Propofol:a review of its non-anaesthetic effects显示文摘 | VASILEIOU I XANTHOS T KOUDOUNA E | 2009 | Eur J Pharmacol2009，605，13： | 1 |
| 3 | Propofol: a review of its nowanaesthetic effects显示文摘 | Vasileiou I Xanthos T Koudouna E | 2011 | Eur J Pharmacol2011，605，13： | 1 |
| 4 | Propofol: a review of its non-anaesthetic effects显示文摘 | Vasileiou I Xanthos T Koudouna E | 2009 | Eur J Pharmacol2009，605，13： | 1 |
| 5 | Propofol; A re-view of its non-anaesthetic effects显示文摘 | Vasileiou I Xanthos T Koudouna E | 2009 | Eur J Pharmacol2009，605，13： | 1 |
| 6 | Combination pharmacotherapy in the treatment of experimental cardiac arrest显示文摘 | Xanthos T Bassiakou E Koudouna E | 2009 | Am J Emerg Med2009，27，6： | 1 |
| 7 | Reviewingmyocardial silent ischemia: specific patient subgroups显示文摘 | Xanthos T Ekmektzoglou KA Papadimitriou L | 2008 | IntJ Cardiol2008，124，2： | 1 |
| 8 | Polymer encapsulation of colloidal asbestos fibrils显示文摘 | XANTHOS M HAMS R T WOOD | 1972 | Applied Polymer Science1972，，16： | 1 |
| 9 | Bi- ochemical markers (NSE, S-100, IL-8) as predictors of neurological out come in patient s after cardiac arrest and return of spontaneous circulation显示文摘 | Ekmektzoglou KA Xanthos T Papadimitriou L | 2007 | Resuscitation2007，75，2： | 1 |
| 10 | Biochemical markets (NSE,S-100,IL-8) as predictors of neurological outcome in patients after cardiac arrest and return of spontaneous circulation显示文摘 | Ekmektzoglou KA Xanthos T Papadimitriou L | | 0，，02： | 1 |
| 11 | Propofol : A review of its non -anaesthetic effects显示文摘 | Vasileiou I Xantho T Koudouna E | 2009 | Eur J Pharmacol2009，605，13： | 1 |
| 12 | Post-cardiac arrest brain mJury: pathophysiology and treatment显示文摘 | Chalkias A Xanthos T | 2012 | J N eurol Sci2012，315，1： | 1 |
| 13 | Pathophysiology and pathogenesis of post-resuscitation myocardial stunning 显示文摘 | Chalkias A Xanthos T | 2012 | Heart Failure Reviews2012，17，1： | 1 |
| 14 | Heart and tumors: location, metastasis, clinical manifestations, diagnostic approaches and therapeutic considerations 显示文摘 | EKMEKTZOGLOU K A SAMELIS G F XANTHOS T | 2008 | J Cardiovasc Med2008，9，8： | 1 |
| 15 | Systematic re- view of the mechanisms driving effective blood flow during adult CPR 显示文摘 | Georgiou M Papathanassoglou E Xanthos T | 2014 | Resuscitation2014，85，11： | 1 |
| 16 | Propofol: a review of its non-anaesthetic effects 显示文摘 | Vasileiou I Xanthos T Koudouna E | 2009 | Eur J Pharmaeol2009，605，： | 1 |
| 17 | Systematic review of the mechanisms driving effective blood flow during adult CPR 显示文摘 | Georgiou M Papathanassoglou E Xanthos T | 2014 | Resuscitation2014，85，11： | 1 |
| 18 | Erythropoetin as a novel agent with pleiotropic effects against acute lung injury 显示文摘 | Kakavas S Demestiha T Vasileiou P Xanthos T | 2011 | Eur J Clin Pharrnacol2011，67，1： | 1 |
| 19 | Abdominal compres- sions do not achieve similar survival rates compared with chest compressions: an experimental study 显示文摘 | Xanthos T Bassiakou E Dontas I | 2011 | Am J Emerg Med2011，29，6： | 1 |
| 20 | Use of the impedance threshold device improves survival rate and neurological outcome in a swine model of asphyxial cardiac arrest显示文摘 | Pantazopoulos I N Xanthos T T Vlachos I | 2012 | Crit Care Med2012，40，3： | 1 |
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