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| 1 | Nonlinear optical endomicroscopy for label-free functional histology in vivo显示文摘This manuscript reports on the first two-photon,label-free,metabolic imaging of biological tissues in vivo at histological resolution on an extremely compact,fiber-optic endomicroscopy platform.This system provides new opportunities for performing noninvasive and functional histological imaging of internal organs in vivo,in situ and in real time.As a routine clinical procedure,traditional histology has made significant impacts on medicine.However,the procedure is invasive and time consuming,suffers random sampling errors,and cannot provide in vivo functional information.The technology reported here features an extremely compact and flexible fiber-optic probe~2 mm in diameter,enabling direct access to internal organs.Unprecedented two-photon imaging quality comparable to a large bench-top laser scanning microscope was achieved through technological innovations in double-clad fiber optics and miniature objective lenses(among many others).In addition to real-time label-free visualization of biological tissues in situ with subcellular histological detail,we demonstrated for the first time in vivo two-photon endomicroscopic metabolic imaging on a functioning mouse kidney model.Such breakthroughs in nonlinear endoscopic imaging capability present numerous promising opportunities for paradigm-shifting applications in both clinical diagnosis and basic research. | Wenxuan Liang Gunnsteinn Hall Bernhard Messerschmidt Ming-Jun Li Xingde Li | 2017 | Light(Science & Applications)2017,6,1: | 6 |
| 2 | Involvement of acid-sensing ion channel 1a in gastric carcinoma cell migration and invasion显示文摘酸的微型环境,特别地酸察觉到的离子隧道 1a (ASIC1a ) ,被报导了象移植一样支持癌房间增长。在这研究,我们在胃的癌(GC ) 的移植和侵略上探索了 ASIC1a 的效果。ASIC1a 表示层次被 immunohistochemistry 从 16 个病人在配对的 GC 和邻近的正常纸巾检验。反向的抄写即时 PCR 和 immunoblotting 被进行与 ASIC1a 小发卡 RNA (shRNA ) 在 transfection 以后在 GC 房间线 AGS 估计 ASIC1a 表示层次。创伤愈合和 transwell 侵略试金被利用检测转移和侵略追随者 ASIC1a silencing。肿瘤形成被用来在 vivo 在 tumorigenicity 检测 ASIC1a 的角色。ASIC1a 表示水平在与非转移相比显示出手术后的转移的 GC 纸巾和非肿瘤纸巾是显著地更高的,这被发现。而且,有 shRNA 的 ASIC1a 的 silencing 显著地下面调整的 ASIC1a 表示和减少的 GC 房间移植和侵略。中等酸的细胞外的环境禁止了 GC 房间生存能力。而且, ASIC1a shRNA 在 vivo 引起了 tumorigenicity 的抑制。我们的学习是 attenuating 的第一份报告在 vitro 并且在由压制 ASIC1a 的 vivo 的 GC 的恶意的显型,并且建议一条新奇途径学习在 ASIC 和 GC 房间移植和侵略之间的关系。 | Xin Chen Xue Sun Zhe Wang Xiaojun Zhou Lu Xu Feng'e Li Xingding Zhang Ji'an Pan Lin Qi Haixin Qian Zhongqi Mao | 2018 | Acta Biochimica et Biophysica Sinica2018,50,5: | 3 |
| 3 | Preparation of natural brucite nanofibers by the dispersion method显示文摘The preparation of natural brucite nanofibers through dispersion by the wet process is described. The test results indicate that brucite fibers can be well dispersed by using sodium dioctyl sulfosuccinate (OT) as the dispersant at a dispersant/fiber mass ratio of 0.15:1, dispersing for 30 min at a water/solid mass ratio of 20:1. The prepared nanofibers were characterized with X-ray diffraction (XRD), scanning electron microscope (SEM), and transmission electron microscope (TEM). It is shown that the prepared single brucite nanofiber is around 30 nm in diameter and the talus of the nonsingle brucite nanofibers is about 50-150 nm in diameter. Natural brucite mineral fibers were treated by the dispersion method to obtain nanomaterials. These fibers have significant advantages over artificial nanofibers both in yield and in cost. | Li Xu Wen Ni Wenping Li Xingde Liu Hailong Yang Xiaoguang Yang | 2008 | Journal of University of Science and Technology Beijing2008,15,4: | 2 |
| 4 | Effect of curcumin on the expression of LDL receptor in mouse macrophages显示文摘 | Chunlei Fan Xingde Wo Ying Qian Jin Yin Liping Gao | 2006 | J Ethnopharmacol2006,105,12: | 1 |
| 5 | On the direct path problem of s-elementary frame wavelets显示文摘In this paper, we discuss the path-connectivity between two s-elementary normalized tight frame wavelets via the so-called direct paths. We show that the existence of such a direct path is equivalent to the non-existence of an atom of a σ-algebra defined over the defining sets of the corresponding frame wavelets, using a mapping defined by the natural translation and dilation operations between the sets. In particular, this gives an equivalent condition for the existence of a direct path between two s-elementary wavelets. | DAI XingDe 1 , DIAO YuanAn 1 & GUO XunXiang 2,1 Department of Mathematics and Statistics, University of North Carolina at Charlotte, Charlotte, NC 28223, USA 2 Department of Mathematics, Southwestern University of Finance and Economics, Chengdu 611130, China | 2010 | Science China Mathematics2010,53,12: | 1 |
| 6 | Effect of curcumin on the expression of LDL receptor in mouse macrophages 显示文摘 | Chunlei F Xingde W Ying Q | 2006 | J Ethnopharmacol2006,105,12: | 1 |
| 7 | High-Speed optical delay line for optical coherence tomography显示文摘 | Liu Xiumei Cobb M J Li Xingde | 2004 | Optics Letters2004,29,1: | 1 |
| 8 | A novel method for measuring photosynthesis using delayed fluorescence of chloroplast 显示文摘 | WANGCL CHENQ XINGD | 2004 | Biosens Bioelectron2004,20,: | 1 |
| 9 | A Method to Quantitatively Detect H-ras Point Mutation Based on Electrochemiluminescence显示文摘 | ZHUD B XINGD SHENXY | 2004 | Biochemical and Biophysical Research Communications2004,324,: | 1 |
| 10 | Benzo-phenone glycosides and epieateehin derivatives from Malania oleifera显示文摘 | WU Xingde CHENG Jintang HE Juan | 2012 | Fitoterapia2012,83,: | 1 |
| 11 | Effeet of cur- cumin the Gene Expression of Low Density Lipoprotein Receptors显示文摘 | Fan Chunlei Qian Ying Wo Xingde | 2005 | Chin J Integer Med2005,11,3: | 1 |
| 12 | Repairing segmental bone defects with living porous ceramics cylinders:an experi mental study in dog femoral femora显示文摘 | Cong Zhang Jianx Wang Xingd Zhang | 2001 | J Biomed Mater Res2001,55,: | 1 |
| 13 | Construction of compactly supported M-band wavelet显示文摘 | Dai Xingde Sun Qiyu | 1999 | Appl Comp Harmonic Anal1999,6,: | 1 |
| 14 | Imaging of subsquamous Barrett’s epithelium with ultrahigh-resolution optical coherence tomography: a histologic correlation study显示文摘 | Michael J. Cobb Joo Ha Hwang Melissa P. Upton Yuchuan Chen Brant K. Oelschlager Douglas E. Wood Michael B. Kimmey Xingde Li | 2010 | Gastrointestinal Endoscopy2010,,: | 1 |
| 15 | Imaging needle for optical coherence tomography 显示文摘 | Xingde Li Christian Chudoba Tony Ko | 2000 | Optical Let- ters2000,25,20: | 1 |
| 16 | AN MRA YIELDS AN ORTHONORMAL WAVELET BASIS——AN OPERATOR THEORETIC PROOF显示文摘Abstract. In this paper we show how to construct a scaling function and an orthonormal wavelet basis from a multiresolution approximation using an operator theoretic method. | DAI XINGDE LU SHIJIE Department of Mathematics, UNCC, Charlotte, UN 28223, USA. Department of Applied Mathematics, Zhejiang University Hangzhou 310027 | 1996 | Applied Mathematics(A Journal of Chinese Universities)1996,11,1: | 1 |
| 17 | Effect of curcumin on the expression of LDL receptor in mouse macrophages 显示文摘 | Chunlei F Xingde W Ying Q | 2006 | J Ethnopharmacol2006,105,12: | 1 |
| 18 | Wavelet sets in RN显示文摘 | Dai Xingde Larnson David R Speegle Darrin M | 1997 | Fourier Anal Appl1997,,3: | 1 |
| 19 | Effect of curcumin on the expression of LDL receptor in mouse macrophages显示文摘 | Chunlei Fan Xingde Wo Ying Qian | 2006 | J Ethnopharmacol2006,105,12: | 1 |
| 20 | Wandering vectors for unitary systems and orthogonal wavelets显示文摘 | Dai Xingde Larson D R | 1998 | NemAmer Math Soc1998,134,640: | 1 |