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178篇 您的检索式:作者名="Wrighton"
    题名 作者 年代 出处 被引量
1Phospho-control of TGF-β superfamily signaling显示文摘转变生长因素的成员 -- 尾(TGF- 尾) 家庭经由 autocrine, paracrine,和内分泌的模式在后生动物的有机体控制大量细胞的回答。因此,发信号的异常 TGF- 尾能在几疾病的致病起一个关键作用,包括癌症。TGF- 尾发信号小径被短 phospho 串联激活,从受体 phosphorylation 到随后的 phosphorylation,下游的信号变换器的激活叫了 R-Smads。R-Smad phosphorylation 状态决定 Smad 复杂集会 / 拆卸,原子进口 / 出口, transcriptional 活动和稳定性,并且因此是在 TGF- 尾发信号的最批评的事件。由特定的磷酸酶的 R-Smads 的 Dephosphorylation 阻止或终止 TGF- 尾发信号,加亮需要认为 Smad (de ) 是 phosphorylation 作为一紧控制了并且动态事件。这篇文章在控制 TGF- 尾发信号和随后的生理的回答的力量和持续时间说明可逆 phosphorylation 的必要角色。Katharine H Wrighton Xia Lin Xin-Hua Feng 2009Cell Research2009,19,1:25
2OneGeology:Making Geological Map Data for the Earth Accessible显示文摘OneGeology is an international initiative of the geological surveys of the world and a flagship project of the'International Year of Planet Earth'.Its aim is to create a digital geological map of the world and to make it available via the web to all.The target scale is l:l million but the project is pragmatic and accepts a range of scales and the best available data.To date, 102 countries are participating in the project and。Chloe Wrighton Catherine Pennington 2009地学前缘2009,16,S1:3
3Fluorescence studies of poly(p-phenyleneethynylene)s: The effect of antheancene substitution显示文摘Swager T M Gil C J Wrighton M S 1995J Phys Chem 991995,,:2
4Small peptides as potent mimetics of the protein hormone erythropoietin 显示文摘Wrighton N C Farrell F X Chang R 1996Science1996,273,5274:1
5Sensitivity of a new commercial enzyme - linked inmunospot assay (T SPOT TB) for diagno- sis of tuberculosis in clinical practice 显示文摘Meier T Eulenbruch HP Wrighton - Smith P 2005Eur J Clin Microbiol Infect Dis2005,24,:1
6The human drug metabolizing cytochromes P450显示文摘Wrighton SA VandenBranden M Ring BJ 1996J Pharmacokinet Biopharm1996,24,5:1
7查看详情显示文摘Bolts J M Wrighton M S 0,,:1
8Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs显示文摘Wang D Guo Y Wrighton SA 2011Pharmacogenomics J2011,11,4:1
9Small peptides as potent mimetics of the protein hormone erythropoietin 显示文摘Wrighton NC Farrel FX Chang R 1996Science1996,273,5274:1
10A novel ecological role of the firmicutes identified in thermophilic microbial fuel cells显示文摘Wrighton K C Agbo P Warnecke F 2008Isme Journal2008,2,11:1
11Intronic polymorphism in CYP3A4affects hepatic expression and response to statin drugs 显示文摘Wang D Guo Y Wrighton SA 2011Pharmacogenomics2011,11,4:1
12Selective electrochemical deposition of polyaniline via photopatterning of a monolayermodified substrate 显示文摘ROZSNYAI L F WRIGHTON M S 1994Journal of the American Chemical Society1994,116,:1
13Fluorescence studies of poly(p-phenyleneethynylene)s: The effect of anthracene substitution显示文摘Swager T M Gil C J Wrighton M S 1995The Journal of Physical Chemistry1995,99,14:1
14Electrocatalytic oxidation of methanol by assemblies of platinum/tin catalyst particles in a conducting polyaniline matrix 显示文摘HABLE C T WRIGHTON M S 1991Langmuir1991,7,:1
15The human drug metabolizing cytochrome P450显示文摘Wrighton SA Van der Branden M Ring BJ 1996J Pharmacokinet Biopharm1996,24,5:1
16Comparison of human and monkey peptide transporters: PEPT1 and PEPT2 显示文摘Zhang EY Emerick RM Pak YA Wrighton SA Hillgren KM 2004Mol Pharm2004,1,3:1
17Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans显示文摘FARID NA KURIHARA A WRIGHTON SA 2010J Clin Pharm2010,50,2:1
18The human hepatic cytochromesP450 involved in drug metabolism显示文摘Wrighton SA Stevens JC 1992Critical Reviews inToxicology1992,22,:1
19Wavelength-dependent primary photoprocesses of Os3(CO)12 in fluid solution and in rigid alkane glasses at low temperature 显示文摘Bentsen J G Wrighton M S 1987J Am Chem Soc1987,109,15:1
20Isolation and characterization of human liver cytochrome P450 2C 19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation显示文摘Wrighton SA Stevens JC Becker GW 1993Arch Bioehem Biophys1993,306,1:1
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