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	题名	作者	年代	出处	被引量
1	Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus显示文摘AIM To propose several alternatives treatment of type 1 hepatorenal syndrome(HRS-1) what is the most severe expression of circulatory dysfunction on patients with portal hypertension.METHODS A group of eleven gastroenterologists and nephrologists performed a structured analysis of available literature.Each expert was designated to review and answer a question.They generated draft statements for evaluation by all the experts.Additional input was obtained from medical community.In order to reach consensus,a modified three-round Delphi technique method was used.According to United States Preventive Services Task Force criteria,the quality of the evidence and level of recommendation supporting each statement was graded.RESULTS Nine questions were formulated.The available evidence was evaluated considering its quality,number of patients included in the studies and the consistency of its results.The generated questions were answered by the expert panel with a high level of agreement.Thus,a therapeutic algorithm was generated.The role of terlipressin and norepinephrine was confirmed as the pharmacologic treatment of choice.On the other hand the use of the combination of octreotide,midodrine and albumin without vasoconstrictors was discouraged.The role of several other options was also evaluated and the available evidence was explored and discussed.Liver transplantation is considered the definitive treatment for HRS-1.The present consensus is an important effort that intends to organize the available strategies based on the available evidence in the literature,the quality of the evidence and the benefits,adverse effects and availability of the therapeutic tools described.CONCLUSION Based on the available evidence the expert panel was able to discriminate the most appropriate therapeutic alternatives for the treatment of HRS-1.	Juan P Arab Juan C Claro Juan P Arancibia Jorge Contreras Fernando Gomez Cristian Munoz Leyla Nazal Eric Roessler Rodrigo Wolff Marco Arrese Carlos Benítez	2016	World Journal of Hepatology2016，8，25：	3
2	Epigenetics : regulation through repression 显示文摘	WOLFFE A P MATZKE M A	1999	Science1999，286，：	1
3	Bound magnetic polarons in semimagnetic semiconductors显示文摘	Wolff P A	1985	Acta Phys A1985，67，2：	1
4	Direct gene transfer into mouse muscle in vivo 显示文摘	Wolff J A Malone R W Williams P	1990	Science1990，247，：	1
5	Direct gene transfer into mouse muscle in vivo显示文摘	Wolff J A Malone R W Williams P	1990	Science1990，247，：	1
6	Endografting increases total volume of AAA repairs but not at the expense of open surgery:experience in more than 1000 patients显示文摘	Wolff KS Prusa AM Polterauer P	2005	J Endovasc Ther2005，12，3：	1
7	UV curing systems for automotive refinish applications 显示文摘	Stropp J P Wolff U Kernaghan S	2006	Progress in Organic Coatings2006，55，2：	1
8	Polymerase chain reaction versus culture for detection of Ureaplasma urealyticum and Mycoplasma hominis in the urogenital tract of adults and the respiratory tract of newborns显示文摘	Abele-Horn M Wolff C Dressel P	1996	Eur J Clin Microbiol Infect Dis1996，15，7：	1
9	Direct gene transfer into mouse muscle in vivo显示文摘	WOLFF J A MALONE R W WILLIANMS P	1990	Science1990，247，：	1
10	Direct gene transfer into mouse muscle in vivo 显示文摘	Wolff JA Malone RW Williams P	1990	Science1990，247，49491：	1
11	Polymerase chain reactionversus culture for detection of Ureaplasma urealyticum and My coplasmahomin is i n the urogenital tract of adults and the respiratory tract of new--borns 显示文摘	Abele--Hom M Wolff C Dressel P	1996	Eur J Clin Microbiol Infect Dis1996，15，：	1
12	Direct gene transfer into mouse in vivo显示文摘	Wolff J A Malone R W Williams P	1990	Science1990，247，：	1
13	Blood levels of organochlorine residues and risk of breast cancer显示文摘	Wolff M S Toniolo P G Lee E W	1994	J Natl Cancer Inst1994，86，21：	1
14	Direct gene transfer into mouse muscle in vivo显示文摘	Wolff JA Malone RW Williams P	1990	Science1990，247，3：	1
15	The Y-box factors: a family of nucleic acid binding proteins conserved from Escherichia coli to man 显示文摘	Wolffe A P Tafuri S Ranjan M	1992	The New Biologist1992，4，4：	1
16	Polymerase chain reaction versus culture for detection of Ureaplasma urealyticumand Mycoplasma hominis in the urogenital tract of adults and the respiratory of newborns 显示文摘	Abele-Hom M Wolff C Dressel P	1996	Eur J Clin Microbiol Infect Dis1996，15，7：	1
17	The coefficient of haze as a measure of particulate elemental carbon显示文摘	Wolff G T Stroup C M Stroup D P	1983	Air Pollu Control Associ1983，33，8：	1
18	Developmental Regulation of Chromatin Structure and Function显示文摘	Wolffe A P	1991	Trends Cell Biol1991，1，23：	1
19	Masking mRNA from translation in somatic cells 显示文摘	Ranjan M Tafuri S R Wolffe A P	1993	Genes & Development1993，7，9：	1
20	Reprogramming nuclei : insight from cloning, nuclear transfer and heterokaryons 显示文摘	KIKYO N WOLFFE A P	2000	J Cell Sci2000，113，：	1

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