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| 1 | 粗饲料种类、可代谢蛋白质浓度、碳水化合物来源对奶牛养分消化率及生产性能的影响显示文摘本试验采用中心组合试验设计对粗饲料来源、可代谢蛋白质(MP)浓度、碳水化合物种类及其互作效应对奶牛养分消化率和生产性能的影响进行了评价。所有日粮(干物质基础)均有50%由苜蓿青贮、玉米青贮构成的粗饲料、10.7%的瘤胃降解蛋白质(RDP)、4.1%~7.1%的瘤胃未降解蛋白质(RUP)、8.8%~12%的MP和22%~30%的淀粉组成。本试验共有15种日粮,试验牛分为6个区组,每个区组6头荷斯坦奶牛,分别进行3个为期21 d的试验。每期按特定顺序饲喂3种日粮后测定试验牛的产奶量、乳成分、采食量及主要营养物质消化率,还考虑了几个主要影响因素间的互作效应。结果表明:日粮淀粉浓度对奶牛养分消化率和生产性能影响较小;用苜蓿青贮代替玉米青贮可降低奶牛的氮消化率、提高中性洗涤纤维(NDF)消化率,还能增加奶牛对日粮干物质(DM)和日粮消化能(DE)摄入量,从而提高能量校正乳(ECM)、乳脂及乳蛋白产量;增加日粮MP浓度可提高奶牛对氮的消化率、ECM和乳蛋白产量,但乳蛋白含量的变化远小于NRC所推荐模型的预测值;DE浓度随淀粉浓度升高呈线性升高,但同时受粗饲料种类和MP浓度互作的影响,即日粮MP浓度较低时,DE浓度会随苜蓿青贮比例升高而降低,而日粮MP浓度较高时,DE浓度会随苜蓿青贮比例升高而升高。 | 郑宇慧 李胜利 Weiss WP St-Pierre N R Willett L B | 2018 | 中国畜牧杂志2018，54，11： | 4 |
| 2 | Immunohistochemical analysis of the Wnt/β-catenin signaling pathway in pancreatic neuroendocrine neoplasms显示文摘AIM: To investigate the role of the Wnt/β-catenin pathway in pancreatic neuroendocrine neoplasms(PanN ENs). METHODS: Tissue microarrays containing 88 PanN ENs were immunohistochemically labeled with antibodies to β-catenin, E-cadherin, adenomatous polyposis coli(APC), chromogranin and synaptophysin. One case had only metastatic tumors resected, whereas others(n = 87) received pancreatectomy with or without partial hepatectomy. Pathology slides, demographic, clinicopathologic, and follow up data were reviewed. Patients' demographics, clinicopathologic features, and immunohistochemical results from 87 primary tumors were compared between patients with low stage(stage Ⅰ/Ⅱ) and high stage(stage Ⅲ/Ⅳ) tumors. In addition, correlation of immunohistochemical results from primary tumors with disease-specific survival(DSS) was evaluated. RESULTS: Strong membranous β-catenin staining in the primary tumor was observed in all 13 stage Ⅲ/Ⅳ Pan NENs as compared to 47%(35/74) of stage Ⅰ/Ⅱtumors(P < 0.01). However, the strong membranous β-catenin staining was unassociated with tumor grade or DSS. Decreased membranous β-catenin staining was associated with decreased membranous E-cadherin labeling. Nuclear β-catenin staining was seen in 15%(2/13) of stage Ⅲ/Ⅳ Pan NENs as compared to 0%(0/74) of stage Ⅰ/Ⅱ tumors(P = 0.02). The case with metastasectomy only also showed nuclear β-catenin staining. Two of the three cases with nuclear β-catenin staining were familial adenomatous polyposis(FAP) patients. Lack of APC expression was seen in 70%(57/81) of the cases, including the 3 cases with nuclear β-catenin staining. Expression of E-cadherin and APC in primary tumor was not correlated with tumor grade, tumor stage, or disease specific survival. CONCLUSION: The Wnt/β-catenin pathway was altered in some PanN ENs, but did not Impact DSS. PanN ENs in FAP patients demonstrated nuclear β-catenin accumulation and loss of APC. | Vivian Weiss Julie Dueber Jesse P Wright Justin Cates Frank Revetta Alexander A Parikh Nipun B Merchant Chanjuan Shi | 2016 | World Journal of Gastrointestinal Oncology2016，8，8： | 3 |
| 3 | Direction finding in the presence of mutual coupling显示文摘 | B Friendlander Anthony J Weiss | 1991 | IEEE Trans on AP1991，39，3： | 2 |
| 4 | Assessing Residual Stress Development and Stress Relaxation in Restrained Concrete Ring Specimens显示文摘 | Hossain A B Weiss J | 2004 | Cement & Concrete Composite2004，26，： | 1 |
| 5 | Zn and Cu isotopic variability in the Alexan- drinka volcanic-hosted massive sulphide (VHMS) ore deposit,Urals,Russia显示文摘 | MASON T F D WEISS D J CHAPMAN J B | 2005 | Chemical Geology2005，221，34： | 1 |
| 6 | Preparation of conductive polypyrrole/polyurethane compositefoams by in situ polymerization of pyrrole显示文摘 | Wang Y B sotzing G A Weiss R A | 2008 | Chem Mater2008，20，7： | 1 |
| 7 | Residual stresses in ceramic plasma - sprayed thermal barrier coatings: Measurement and calculation显示文摘 | Levit M Grimberc I Weiss B Z | 1996 | Materials Science & Engineering A1996，206，1： | 1 |
| 8 | Effect of interdiffusion on the subbands in an Alx Ga1-xAs single quantum-well structure显示文摘 | Li E H Weiss B L Chan K S | 1992 | Phys Rev B1992，46，15： | 1 |
| 9 | Preparation and mechanical properties of ultrafine grained metals显示文摘 | Gunther B Baal man A Weiss H | 1990 | Journal of materials research1990，5，： | 1 |
| 10 | Direction finding using spatial smoothing with interpolated arrays 显示文摘 | FRIEDLANDER B WEISS A J | 1993 | IEEE Transaction on Signal Processing1993，41，4： | 1 |
| 11 | Eigenstructure methods for direction finding with sensor gain and phase uncertainties 显示文摘 | Weiss A J Friedlander B | 1990 | Circutis Systems Signal Process1990，9，3： | 1 |
| 12 | Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996 显示文摘 | Weiss BM Zemp L Seifert B | 1998 | J Am Coll Cardiol1998，31，： | 1 |
| 13 | Cross-linking of interfacial layers affects the salt and temperature stability of multilayered emulsions consisting of fish gelatin and sugar beet pectin显示文摘 | Zeeb B Fischer L Weiss J | 2011 | J Agr Food Chem2011，59，10： | 1 |
| 14 | Multicomponent Ti-Zr-N and Ti-Nb-N coatings deposited by vacuum arc显示文摘 | GRIMBERG I ZHITOMIRSKY V M BOXMAN R L GOLDSMITH S WEISS B Z | 1998 | Surface and Coatings Technology1998，，： | 1 |
| 15 | Ursodeoxycholate stabilizes phospholipid- rich membranes and mimics the effect of cholesterol: investigations on large unilamellar vesicles 显示文摘 | Deisinger B Weiss A | 1997 | Biochim Biophys Acta1997，1326，2： | 1 |
| 16 | Eigenstructure methods for direction finding with sensor gain and phase uncertainties显示文摘 | WEISS A J FRIEDLANDER B | 1990 | Circuits Syst Signal Processing1990，9，2： | 1 |
| 17 | Bubbleless fiber aerator for surface waters显示文摘 | WEISS P T OAKLEY B T GULLIVER J S | 1996 | Journal of Environmental Engineering1996，122，： | 1 |
| 18 | Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system显示文摘 | Reynolds B A Weiss S | 1992 | Science1992，27，5052： | 1 |
| 19 | Vulnerability of children and the developing brain toneurotoxi chazards显示文摘 | Weiss B | 2000 | Environ Health Perspect2000，108，： | 1 |
| 20 | Reduction of postharvest decay in organic citrus fruits by a short hot water brushing treatment显示文摘 | PORAT R DAUS A WEISS B | 2000 | Postharvest Biol Technol2000，18，： | 1 |
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